메뉴 건너뛰기




Volumn 237, Issue 1, 2013, Pages 164-171

The neuroprotective effects of GLP-1: Possible treatments for cognitive deficits in individuals with mood disorders

Author keywords

Cognition; GLP 1; Incretins; Mood disorders; Neuroprotection

Indexed keywords

EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; INCRETIN; LIRAGLUTIDE; PLACEBO;

EID: 84867435685     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2012.09.021     Document Type: Review
Times cited : (81)

References (66)
  • 1
    • 77954667232 scopus 로고    scopus 로고
    • Diagnostic features, prevalence, and impact of bipolar disorder
    • June
    • Ketter T.A. Diagnostic features, prevalence, and impact of bipolar disorder. Journal of Clinical Psychiatry 2010, 71(June (6)):e14.
    • (2010) Journal of Clinical Psychiatry , vol.71 , Issue.6
    • Ketter, T.A.1
  • 3
    • 84856472879 scopus 로고    scopus 로고
    • Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy
    • Millan M.J., Agid Y., Brune M., Bullmore E.T., Carter C.S., Clayton N.S., et al. Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nature Reviews Drug Discovery 2012, 11(2):141-168.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.2 , pp. 141-168
    • Millan, M.J.1    Agid, Y.2    Brune, M.3    Bullmore, E.T.4    Carter, C.S.5    Clayton, N.S.6
  • 4
    • 74949104026 scopus 로고    scopus 로고
    • Effect of second-generation antipsychotics on cognition: current issues and future challenges
    • January
    • Hill S.K., Bishop J.R., Palumbo D., Sweeney J.A. Effect of second-generation antipsychotics on cognition: current issues and future challenges. Expert Review of Neurotherapeutics 2010, 10(January (1)):43-57.
    • (2010) Expert Review of Neurotherapeutics , vol.10 , Issue.1 , pp. 43-57
    • Hill, S.K.1    Bishop, J.R.2    Palumbo, D.3    Sweeney, J.A.4
  • 5
    • 0346216156 scopus 로고    scopus 로고
    • Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI
    • December
    • den H.T., Vermeer S.E., van Dijk E.J., Prins N.D., Koudstaal P.J., Hofman A., et al. Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia 2003, 46(December (12)):1604-1610.
    • (2003) Diabetologia , vol.46 , Issue.12 , pp. 1604-1610
    • den, H.T.1    Vermeer, S.E.2    van Dijk, E.J.3    Prins, N.D.4    Koudstaal, P.J.5    Hofman, A.6
  • 6
    • 0030741609 scopus 로고    scopus 로고
    • Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease
    • March
    • Convit A., De Leon M.J., Tarshish C., De S.S., Tsui W., Rusinek H., et al. Specific hippocampal volume reductions in individuals at risk for Alzheimer's disease. Neurobiology of Aging 1997, 18(March (2)):131-138.
    • (1997) Neurobiology of Aging , vol.18 , Issue.2 , pp. 131-138
    • Convit, A.1    De Leon, M.J.2    Tarshish, C.3    De, S.S.4    Tsui, W.5    Rusinek, H.6
  • 7
    • 33644764957 scopus 로고    scopus 로고
    • Effects of type 1 diabetes on gray matter density as measured by voxel-based morphometry
    • February
    • Musen G., Lyoo I.K., Sparks C.R., Weinger K., Hwang J., Ryan C.M., et al. Effects of type 1 diabetes on gray matter density as measured by voxel-based morphometry. Diabetes 2006, 55(February (2)):326-333.
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 326-333
    • Musen, G.1    Lyoo, I.K.2    Sparks, C.R.3    Weinger, K.4    Hwang, J.5    Ryan, C.M.6
  • 8
    • 0345118198 scopus 로고    scopus 로고
    • Neurocognitive impairment in drug-free patients with major depressive disorder
    • March
    • Porter R.J., Gallagher P., Thompson J.M., Young A.H. Neurocognitive impairment in drug-free patients with major depressive disorder. British Journal of Psychiatry 2003, 182(March):214-220.
    • (2003) British Journal of Psychiatry , vol.182 , pp. 214-220
    • Porter, R.J.1    Gallagher, P.2    Thompson, J.M.3    Young, A.H.4
  • 9
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus
    • November
    • Gispen W.H., Biessels G.J. Cognition and synaptic plasticity in diabetes mellitus. Trends in Neurosciences 2000, 23(November (11)):542-549.
    • (2000) Trends in Neurosciences , vol.23 , Issue.11 , pp. 542-549
    • Gispen, W.H.1    Biessels, G.J.2
  • 12
    • 78650753885 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications
    • January
    • Nauck M.A. Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications. American Journal of Medicine 2011, 124(January (1 Suppl.)):S3-S18.
    • (2011) American Journal of Medicine , vol.124 , Issue.1 SUPPL.
    • Nauck, M.A.1
  • 13
    • 79960262492 scopus 로고    scopus 로고
    • Management of type 2 diabetes: new and future developments in treatment
    • July
    • Tahrani A.A., Bailey C.J., Del P.S., Barnett A.H. Management of type 2 diabetes: new and future developments in treatment. Lancet 2011, 378(July (9786)):182-197.
    • (2011) Lancet , vol.378 , Issue.9786 , pp. 182-197
    • Tahrani, A.A.1    Bailey, C.J.2    Del, P.S.3    Barnett, A.H.4
  • 14
    • 0026775150 scopus 로고
    • Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
    • September
    • Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proceedings of the National Academy of Sciences of the United States of America 1992, 89(September (18)):8641-8645.
    • (1992) Proceedings of the National Academy of Sciences of the United States of America , vol.89 , Issue.18 , pp. 8641-8645
    • Thorens, B.1
  • 15
    • 3042792777 scopus 로고    scopus 로고
    • Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid
    • August
    • Green B.D., Gault V.A., Flatt P.R., Harriott P., Greer B., O'Harte F.P. Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid. Archives of Biochemistry and Biophysics 2004, 428(August (2)):136-143.
    • (2004) Archives of Biochemistry and Biophysics , vol.428 , Issue.2 , pp. 136-143
    • Green, B.D.1    Gault, V.A.2    Flatt, P.R.3    Harriott, P.4    Greer, B.5    O'Harte, F.P.6
  • 16
    • 13344282056 scopus 로고    scopus 로고
    • A role for glucagon-like peptide-1 in the central regulation of feeding
    • January
    • Turton M.D., O'Shea D., Gunn I., Beak S.A., Edwards C.M., Meeran K., et al. A role for glucagon-like peptide-1 in the central regulation of feeding. Nature 1996, 379(January (6560)):69-72.
    • (1996) Nature , vol.379 , Issue.6560 , pp. 69-72
    • Turton, M.D.1    O'Shea, D.2    Gunn, I.3    Beak, S.A.4    Edwards, C.M.5    Meeran, K.6
  • 17
    • 10244241840 scopus 로고    scopus 로고
    • Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake
    • November
    • Navarro M., Rodriquez de F.F., Alvarez E., Chowen J.A., Zueco J.A., Gomez R., et al. Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake. Journal of Neurochemistry 1996, 67(November (5)):1982-1991.
    • (1996) Journal of Neurochemistry , vol.67 , Issue.5 , pp. 1982-1991
    • Navarro, M.1    Rodriquez de, F.F.2    Alvarez, E.3    Chowen, J.A.4    Zueco, J.A.5    Gomez, R.6
  • 18
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • November
    • Goke R., Larsen P.J., Mikkelsen J.D., Sheikh S.P. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. European Journal of Neuroscience 1995, 7(November (11)):2294-2300.
    • (1995) European Journal of Neuroscience , vol.7 , Issue.11 , pp. 2294-2300
    • Goke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 19
    • 57649192347 scopus 로고    scopus 로고
    • Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity
    • October
    • Cabou C., Campistron G., Marsollier N., Leloup C., Cruciani-Guglielmacci C., Penicaud L., et al. Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity. Diabetes 2008, 57(October (10)):2577-2587.
    • (2008) Diabetes , vol.57 , Issue.10 , pp. 2577-2587
    • Cabou, C.1    Campistron, G.2    Marsollier, N.3    Leloup, C.4    Cruciani-Guglielmacci, C.5    Penicaud, L.6
  • 20
    • 0141446228 scopus 로고    scopus 로고
    • Enhancing incretin action for the treatment of type 2 diabetes
    • October
    • Drucker D.J. Enhancing incretin action for the treatment of type 2 diabetes. Diabetes Care 2003, 26(October (10)):2929-2940.
    • (2003) Diabetes Care , vol.26 , Issue.10 , pp. 2929-2940
    • Drucker, D.J.1
  • 21
    • 0141461415 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
    • September
    • During M.J., Cao L., Zuzga D.S., Francis J.S., Fitzsimons H.L., Jiao X., et al. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nature Medicine 2003, 9(September (9)):1173-1179.
    • (2003) Nature Medicine , vol.9 , Issue.9 , pp. 1173-1179
    • During, M.J.1    Cao, L.2    Zuzga, D.S.3    Francis, J.S.4    Fitzsimons, H.L.5    Jiao, X.6
  • 22
    • 77649187436 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease
    • March
    • McClean P.L., Gault V.A., Harriott P., Holscher C. Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease. European Journal of Pharmacology 2010, 630(March (1-3)):158-162.
    • (2010) European Journal of Pharmacology , vol.630 , Issue.1-3 , pp. 158-162
    • McClean, P.L.1    Gault, V.A.2    Harriott, P.3    Holscher, C.4
  • 23
    • 78649385516 scopus 로고    scopus 로고
    • The role of GLP-1 in neuronal activity and neurodegeneration
    • Holscher C. The role of GLP-1 in neuronal activity and neurodegeneration. Vitamins and Hormones 2010, 84:331-354.
    • (2010) Vitamins and Hormones , vol.84 , pp. 331-354
    • Holscher, C.1
  • 24
    • 34248223285 scopus 로고    scopus 로고
    • Biology of incretins: GLP-1 and GIP
    • May
    • Baggio L.L., Drucker D.J. Biology of incretins: GLP-1 and GIP. Gastroenterology 2007, 132(May (6)):2131-2157.
    • (2007) Gastroenterology , vol.132 , Issue.6 , pp. 2131-2157
    • Baggio, L.L.1    Drucker, D.J.2
  • 25
    • 84855257784 scopus 로고    scopus 로고
    • Evolving treatment strategies for the management of type 2 diabetes
    • January
    • Cefalu W.T. Evolving treatment strategies for the management of type 2 diabetes. American Journal of the Medical Sciences 2012, 343(January (1)):21-26.
    • (2012) American Journal of the Medical Sciences , vol.343 , Issue.1 , pp. 21-26
    • Cefalu, W.T.1
  • 26
    • 0028803336 scopus 로고
    • Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects
    • September
    • Deacon C.F., Nauck M.A., Toft-Nielsen M., Pridal L., Willms B., Holst J.J. Both subcutaneously and intravenously administered glucagon-like peptide I are rapidly degraded from the NH2-terminus in type II diabetic patients and in healthy subjects. Diabetes 1995, 44(September (9)):1126-1131.
    • (1995) Diabetes , vol.44 , Issue.9 , pp. 1126-1131
    • Deacon, C.F.1    Nauck, M.A.2    Toft-Nielsen, M.3    Pridal, L.4    Willms, B.5    Holst, J.J.6
  • 28
    • 77953613604 scopus 로고    scopus 로고
    • Once-weekly GLP-1 agonists: how do they differ from exenatide and liraglutide?
    • April
    • Christensen M., Knop F.K. Once-weekly GLP-1 agonists: how do they differ from exenatide and liraglutide?. Current Diabetes Reports 2010, 10(April (2)):124-132.
    • (2010) Current Diabetes Reports , vol.10 , Issue.2 , pp. 124-132
    • Christensen, M.1    Knop, F.K.2
  • 30
    • 13644268431 scopus 로고    scopus 로고
    • The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem
    • February
    • Alvarez E., Martinez M.D., Roncero I., Chowen J.A., Garcia-Cuartero B., Gispert J.D., et al. The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem. Journal of Neurochemistry 2005, 92(February (4)):798-806.
    • (2005) Journal of Neurochemistry , vol.92 , Issue.4 , pp. 798-806
    • Alvarez, E.1    Martinez, M.D.2    Roncero, I.3    Chowen, J.A.4    Garcia-Cuartero, B.5    Gispert, J.D.6
  • 31
    • 0033545166 scopus 로고    scopus 로고
    • Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
    • January
    • Merchenthaler I., Lane M., Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. Journal of Comparative Neurology 1999, 403(January (2)):261-280.
    • (1999) Journal of Comparative Neurology , vol.403 , Issue.2 , pp. 261-280
    • Merchenthaler, I.1    Lane, M.2    Shughrue, P.3
  • 33
    • 50949094723 scopus 로고    scopus 로고
    • Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake
    • August
    • Sandoval D.A., Bagnol D., Woods S.C., D'Alessio D.A., Seeley R.J. Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake. Diabetes 2008, 57(August (8)):2046-2054.
    • (2008) Diabetes , vol.57 , Issue.8 , pp. 2046-2054
    • Sandoval, D.A.1    Bagnol, D.2    Woods, S.C.3    D'Alessio, D.A.4    Seeley, R.J.5
  • 34
    • 0032830989 scopus 로고    scopus 로고
    • Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus
    • August
    • Rinaman L. Interoceptive stress activates glucagon-like peptide-1 neurons that project to the hypothalamus. American Journal of Physiology 1999, 277(August (2 Pt 2)):R582-R590.
    • (1999) American Journal of Physiology , vol.277 , Issue.2 PART 2
    • Rinaman, L.1
  • 35
    • 0036307872 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
    • July
    • Yamamoto H., Lee C.E., Marcus J.N., Williams T.D., Overton J.M., Lopez M.E., et al. Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons. Journal of Clinical Investigation 2002, 110(July (1)):43-52.
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.1 , pp. 43-52
    • Yamamoto, H.1    Lee, C.E.2    Marcus, J.N.3    Williams, T.D.4    Overton, J.M.5    Lopez, M.E.6
  • 37
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier
    • February
    • Kastin A.J., Akerstrom V., Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier. Journal of Molecular Neuroscience 2002, 18(February (1-2)):7-14.
    • (2002) Journal of Molecular Neuroscience , vol.18 , Issue.1-2 , pp. 7-14
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 38
    • 0345726358 scopus 로고    scopus 로고
    • Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites
    • April
    • Yamamoto H., Kishi T., Lee C.E., Choi B.J., Fang H., Hollenberg A.N., et al. Glucagon-like peptide-1-responsive catecholamine neurons in the area postrema link peripheral glucagon-like peptide-1 with central autonomic control sites. Journal of Neuroscience 2003, 23(April (7)):2939-2946.
    • (2003) Journal of Neuroscience , vol.23 , Issue.7 , pp. 2939-2946
    • Yamamoto, H.1    Kishi, T.2    Lee, C.E.3    Choi, B.J.4    Fang, H.5    Hollenberg, A.N.6
  • 39
    • 2342429486 scopus 로고    scopus 로고
    • Passage of VIP/PACAP/secretin family across the blood-brain barrier: therapeutic effects
    • Dogrukol-Ak D., Tore F., Tuncel N. Passage of VIP/PACAP/secretin family across the blood-brain barrier: therapeutic effects. Current Pharmaceutical Design 2004, 10(12):1325-1340.
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.12 , pp. 1325-1340
    • Dogrukol-Ak, D.1    Tore, F.2    Tuncel, N.3
  • 41
    • 84865521108 scopus 로고    scopus 로고
    • Effects of the glucagon-like polypeptide-1 analogue (Val(8))GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain
    • September
    • McGovern S.F., Hunter K., Holscher C. Effects of the glucagon-like polypeptide-1 analogue (Val(8))GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain. Brain Research 2012, 1473(September):204-213.
    • (2012) Brain Research , vol.1473 , pp. 204-213
    • McGovern, S.F.1    Hunter, K.2    Holscher, C.3
  • 42
    • 84858713174 scopus 로고    scopus 로고
    • Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
    • Hunter K., Holscher C. Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis. BMC Neuroscience 2012, 13:33.
    • (2012) BMC Neuroscience , vol.13 , pp. 33
    • Hunter, K.1    Holscher, C.2
  • 43
    • 0038248960 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron
    • June
    • Perry T., Lahiri D.K., Sambamurti K., Chen D., Mattson M.P., Egan J.M., et al. Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron. Journal of Neuroscience Research 2003, 72(June (5)):603-612.
    • (2003) Journal of Neuroscience Research , vol.72 , Issue.5 , pp. 603-612
    • Perry, T.1    Lahiri, D.K.2    Sambamurti, K.3    Chen, D.4    Mattson, M.P.5    Egan, J.M.6
  • 45
    • 67949112601 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway
    • September
    • Kimura R., Okouchi M., Fujioka H., Ichiyanagi A., Ryuge F., Mizuno T., et al. Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway. Neuroscience 2009, 162(September (4)):1212-1219.
    • (2009) Neuroscience , vol.162 , Issue.4 , pp. 1212-1219
    • Kimura, R.1    Okouchi, M.2    Fujioka, H.3    Ichiyanagi, A.4    Ryuge, F.5    Mizuno, T.6
  • 46
    • 48349144982 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction
    • September
    • Biswas S.C., Buteau J., Greene L.A. Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. Neurochemical Research 2008, 33(September (9)):1845-1851.
    • (2008) Neurochemical Research , vol.33 , Issue.9 , pp. 1845-1851
    • Biswas, S.C.1    Buteau, J.2    Greene, L.A.3
  • 47
    • 79955749452 scopus 로고    scopus 로고
    • The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
    • April
    • McClean P.L., Parthsarathy V., Faivre E., Holscher C. The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease. Journal of Neuroscience 2011, 31(April (17)):6587-6594.
    • (2011) Journal of Neuroscience , vol.31 , Issue.17 , pp. 6587-6594
    • McClean, P.L.1    Parthsarathy, V.2    Faivre, E.3    Holscher, C.4
  • 48
    • 82755176046 scopus 로고    scopus 로고
    • Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
    • February
    • Gengler S., McClean P.L., McCurtin R., Gault V.A., Holscher C. Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice. Neurobiology of Aging 2012, 33(February (2)):265-276.
    • (2012) Neurobiology of Aging , vol.33 , Issue.2 , pp. 265-276
    • Gengler, S.1    McClean, P.L.2    McCurtin, R.3    Gault, V.A.4    Holscher, C.5
  • 49
    • 0345305844 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons
    • December
    • Gilman C.P., Perry T., Furukawa K., Grieg N.H., Egan J.M., Mattson M.P. Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. Journal of Neurochemistry 2003, 87(December (5)):1137-1144.
    • (2003) Journal of Neurochemistry , vol.87 , Issue.5 , pp. 1137-1144
    • Gilman, C.P.1    Perry, T.2    Furukawa, K.3    Grieg, N.H.4    Egan, J.M.5    Mattson, M.P.6
  • 50
    • 77950352189 scopus 로고    scopus 로고
    • GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease
    • Li Y., Duffy K.B., Ottinger M.A., Ray B., Bailey J.A., Holloway H.W., et al. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. Journal of Alzheimer's Disease 2010, 19(4):1205-1219.
    • (2010) Journal of Alzheimer's Disease , vol.19 , Issue.4 , pp. 1205-1219
    • Li, Y.1    Duffy, K.B.2    Ottinger, M.A.3    Ray, B.4    Bailey, J.A.5    Holloway, H.W.6
  • 52
    • 0033519562 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus
    • June
    • Oka J.I., Goto N., Kameyama T. Glucagon-like peptide-1 modulates neuronal activity in the rat's hippocampus. Neuroreport 1999, 10(June (8)):1643-1646.
    • (1999) Neuroreport , vol.10 , Issue.8 , pp. 1643-1646
    • Oka, J.I.1    Goto, N.2    Kameyama, T.3
  • 53
    • 77957126457 scopus 로고    scopus 로고
    • Val8-glucagon-like peptide-1 protects against Abeta1-40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats
    • November
    • Wang X.H., Li L., Holscher C., Pan Y.F., Chen X.R., Qi J.S. Val8-glucagon-like peptide-1 protects against Abeta1-40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats. Neuroscience 2010, 170(November (4)):1239-1248.
    • (2010) Neuroscience , vol.170 , Issue.4 , pp. 1239-1248
    • Wang, X.H.1    Li, L.2    Holscher, C.3    Pan, Y.F.4    Chen, X.R.5    Qi, J.S.6
  • 54
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • June
    • Gault V.A., Holscher C. GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. European Journal of Pharmacology 2008, 587(June (1-3)):112-117.
    • (2008) European Journal of Pharmacology , vol.587 , Issue.1-3 , pp. 112-117
    • Gault, V.A.1    Holscher, C.2
  • 55
    • 77956134398 scopus 로고    scopus 로고
    • Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance
    • October
    • Porter D.W., Kerr B.D., Flatt P.R., Holscher C., Gault V.A. Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance. Diabetes, Obesity and Metabolism 2010, 12(October (10)):891-899.
    • (2010) Diabetes, Obesity and Metabolism , vol.12 , Issue.10 , pp. 891-899
    • Porter, D.W.1    Kerr, B.D.2    Flatt, P.R.3    Holscher, C.4    Gault, V.A.5
  • 56
    • 77955470617 scopus 로고    scopus 로고
    • Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet
    • August
    • Gault V.A., Porter W.D., Flatt P.R., Holscher C. Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet. International Journal of Obesity (London) 2010, 34(August (8)):1341-1344.
    • (2010) International Journal of Obesity (London) , vol.34 , Issue.8 , pp. 1341-1344
    • Gault, V.A.1    Porter, W.D.2    Flatt, P.R.3    Holscher, C.4
  • 57
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease
    • December
    • Abbas T., Faivre E., Holscher C. Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease. Behavioural Brain Research 2009, 205(December (1)):265-271.
    • (2009) Behavioural Brain Research , vol.205 , Issue.1 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Holscher, C.3
  • 58
    • 0036182251 scopus 로고    scopus 로고
    • A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells
    • March
    • Perry T., Lahiri D.K., Chen D., Zhou J., Shaw K.T., Egan J.M., et al. A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells. Journal of Pharmacology and Experimental Therapeutics 2002, 300(March (3)):958-966.
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.300 , Issue.3 , pp. 958-966
    • Perry, T.1    Lahiri, D.K.2    Chen, D.3    Zhou, J.4    Shaw, K.T.5    Egan, J.M.6
  • 59
    • 38849196303 scopus 로고    scopus 로고
    • Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease
    • February
    • Bertilsson G., Patrone C., Zachrisson O., Andersson A., Dannaeus K., Heidrich J., et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. Journal of Neuroscience Research 2008, 86(February (2)):326-338.
    • (2008) Journal of Neuroscience Research , vol.86 , Issue.2 , pp. 326-338
    • Bertilsson, G.1    Patrone, C.2    Zachrisson, O.3    Andersson, A.4    Dannaeus, K.5    Heidrich, J.6
  • 60
    • 79751479118 scopus 로고    scopus 로고
    • Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
    • April
    • Hamilton A., Patterson S., Porter D., Gault V.A., Holscher C. Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain. Journal of Neuroscience Research 2011, 89(April (4)):481-489.
    • (2011) Journal of Neuroscience Research , vol.89 , Issue.4 , pp. 481-489
    • Hamilton, A.1    Patterson, S.2    Porter, D.3    Gault, V.A.4    Holscher, C.5
  • 61
    • 33846501672 scopus 로고    scopus 로고
    • Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy
    • February
    • Perry T., Holloway H.W., Weerasuriya A., Mouton P.R., Duffy K., Mattison J.A., et al. Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy. Experimental Neurology 2007, 203(February (2)):293-301.
    • (2007) Experimental Neurology , vol.203 , Issue.2 , pp. 293-301
    • Perry, T.1    Holloway, H.W.2    Weerasuriya, A.3    Mouton, P.R.4    Duffy, K.5    Mattison, J.A.6
  • 62
    • 72749091486 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons
    • December
    • Belsham D.D., Fick L.J., Dalvi P.S., Centeno M.L., Chalmers J.A., Lee P.K., et al. Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons. FASEB Journal 2009, 23(December (12)):4256-4265.
    • (2009) FASEB Journal , vol.23 , Issue.12 , pp. 4256-4265
    • Belsham, D.D.1    Fick, L.J.2    Dalvi, P.S.3    Centeno, M.L.4    Chalmers, J.A.5    Lee, P.K.6
  • 63
    • 55549139200 scopus 로고    scopus 로고
    • Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats
    • Stranahan A.M., Norman E.D., Lee K., Cutler R.G., Telljohann R.S., Egan J.M., et al. Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats. Hippocampus 2008, 18(11):1085-1088.
    • (2008) Hippocampus , vol.18 , Issue.11 , pp. 1085-1088
    • Stranahan, A.M.1    Norman, E.D.2    Lee, K.3    Cutler, R.G.4    Telljohann, R.S.5    Egan, J.M.6
  • 64
    • 78649745810 scopus 로고    scopus 로고
    • The glucagon-like peptide 1 receptor agonist exendin-4 improves reference memory performance and decreases immobility in the forced swim test
    • January
    • Isacson R., Nielsen E., Dannaeus K., Bertilsson G., Patrone C., Zachrisson O., et al. The glucagon-like peptide 1 receptor agonist exendin-4 improves reference memory performance and decreases immobility in the forced swim test. European Journal of Pharmacology 2011, 650(January (1)):249-255.
    • (2011) European Journal of Pharmacology , vol.650 , Issue.1 , pp. 249-255
    • Isacson, R.1    Nielsen, E.2    Dannaeus, K.3    Bertilsson, G.4    Patrone, C.5    Zachrisson, O.6
  • 65
    • 64249126355 scopus 로고    scopus 로고
    • The influences of juvenile diabetes on memory and hippocampal plasticity in rats: improving effects of glucagon-like peptide-1
    • May
    • Iwai T., Suzuki M., Kobayashi K., Mori K., Mogi Y., Oka J. The influences of juvenile diabetes on memory and hippocampal plasticity in rats: improving effects of glucagon-like peptide-1. Neuroscience Research 2009, 64(May (1)):67-74.
    • (2009) Neuroscience Research , vol.64 , Issue.1 , pp. 67-74
    • Iwai, T.1    Suzuki, M.2    Kobayashi, K.3    Mori, K.4    Mogi, Y.5    Oka, J.6
  • 66
    • 0038382373 scopus 로고    scopus 로고
    • CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors
    • July
    • Kinzig K.P., D'Alessio D.A., Herman J.P., Sakai R.R., Vahl T.P., Figueiredo H.F., et al. CNS glucagon-like peptide-1 receptors mediate endocrine and anxiety responses to interoceptive and psychogenic stressors. Journal of Neuroscience 2003, 23(July (15)):6163-6170.
    • (2003) Journal of Neuroscience , vol.23 , Issue.15 , pp. 6163-6170
    • Kinzig, K.P.1    D'Alessio, D.A.2    Herman, J.P.3    Sakai, R.R.4    Vahl, T.P.5    Figueiredo, H.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.