메뉴 건너뛰기




Volumn 12, Issue 10, 2010, Pages 891-899

Four weeks administration of Liraglutide improves memory and learning as well as glycaemic control in mice with high fat dietary-induced obesity and insulin resistance

Author keywords

Cognitive function; GLP 1; Insulin resistance; Liraglutide; LTP; Obesity

Indexed keywords

GLUCOSE; INSULIN; LIRAGLUTIDE; SODIUM CHLORIDE;

EID: 77956134398     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2010.01259.x     Document Type: Article
Times cited : (132)

References (41)
  • 1
    • 0034108646 scopus 로고    scopus 로고
    • Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once-daily administration.
    • Knudsen LB, Nielsen PF, Huusfeldt PO. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once-daily administration. J Med Chem 2001, 43:1664-1669..
    • (2001) J Med Chem , vol.43
    • Knudsen, L.B.1    Nielsen, P.F.2    Huusfeldt, P.O.3
  • 2
    • 0037844361 scopus 로고    scopus 로고
    • Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative.
    • Agersø H, Vicini P. Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative. Eur J Pharmacol 2003, 19:141-150..
    • (2003) Eur J Pharmacol , vol.19
    • Agersø, H.1    Vicini, P.2
  • 3
    • 3843121153 scopus 로고    scopus 로고
    • Glucagon-like peptide-1: the basis of a new class of treatment for type 2 diabetes.
    • Knudsen LB. Glucagon-like peptide-1: the basis of a new class of treatment for type 2 diabetes. J Med Chem 2004, 47:4128-4134..
    • (2004) J Med Chem , vol.47
    • Knudsen, L.B.1
  • 4
    • 73349106529 scopus 로고    scopus 로고
    • The effects of glucagon-like peptide-1 on the beta cell.
    • Vilsbøll T. The effects of glucagon-like peptide-1 on the beta cell. Diabetes Obes Metab 2009, 11:11-18..
    • (2009) Diabetes Obes Metab , vol.11
    • Vilsbøll, T.1
  • 5
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus.
    • Lovshin JA, Drucker DJ. Incretin-based therapies for type 2 diabetes mellitus. Nat Rev Endocrinol 2009, 5:262-269..
    • (2009) Nat Rev Endocrinol , vol.5
    • Lovshin, J.A.1    Drucker, D.J.2
  • 6
    • 0036784675 scopus 로고    scopus 로고
    • The long-acting GLP-1 derivative NN2211 ameliorates glycaemia and increases beta-cell mass in diabetic mice.
    • Rolin B, Larsen MO, Gotfredsen CF. The long-acting GLP-1 derivative NN2211 ameliorates glycaemia and increases beta-cell mass in diabetic mice. Am J Physiol Endocrinol Metab 2002, 283:745-752..
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • Rolin, B.1    Larsen, M.O.2    Gotfredsen, C.F.3
  • 7
    • 15744381238 scopus 로고    scopus 로고
    • The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro.
    • Bregenholt S, Møldrup A, Blume N. The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro. Biochem Biophys Res Commun 2005, 330:577-584..
    • (2005) Biochem Biophys Res Commun , vol.330
    • Bregenholt, S.1    Møldrup, A.2    Blume, N.3
  • 8
    • 65549144889 scopus 로고    scopus 로고
    • Recent advances in antidiabetic drug therapies targeting the enteroinsular axis.
    • Flatt PR, Bailey CJ, Green BD. Recent advances in antidiabetic drug therapies targeting the enteroinsular axis. Curr Drug Metab 2009, 10:125-137..
    • (2009) Curr Drug Metab , vol.10
    • Flatt, P.R.1    Bailey, C.J.2    Green, B.D.3
  • 9
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain-barrier.
    • Kastin AJ, Akerstrom V, Pan W. Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain-barrier. J Mol Neurosci 2002, 18:7-14..
    • (2002) J Mol Neurosci , vol.18
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 10
    • 0037349072 scopus 로고    scopus 로고
    • Entry of exendin-4 into brain is rapid but may be limited at high doses.
    • Kastin AJ, Akerstrom V. Entry of exendin-4 into brain is rapid but may be limited at high doses. Int J Obes Relat Metab Disord 2003, 27:313-318..
    • (2003) Int J Obes Relat Metab Disord , vol.27
    • Kastin, A.J.1    Akerstrom, V.2
  • 11
    • 77649187436 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease.
    • McClean PL, Gault VA, Harriott P, Hölscher C. Glucagon-like peptide-1 analogues enhance synaptic plasticity in the brain: a link between diabetes and Alzheimer's disease. Eur J Pharmacol 2010, 630:158-162..
    • (2010) Eur J Pharmacol , vol.630
    • McClean, P.L.1    Gault, V.A.2    Harriott, P.3    Hölscher, C.4
  • 12
    • 0141461415 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor is involved in learning and neuroprotection.
    • During MJ, Cao L, Zuzga DS. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med 2003, 9:1173-1179..
    • (2003) Nat Med , vol.9
    • During, M.J.1    Cao, L.2    Zuzga, D.S.3
  • 13
    • 69549128161 scopus 로고    scopus 로고
    • Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system.
    • Hamilton A, Hölscher C. Receptors for the incretin glucagon-like peptide-1 are expressed on neurons in the central nervous system. Neuroreport 2009, 20:1161-1166..
    • (2009) Neuroreport , vol.20
    • Hamilton, A.1    Hölscher, C.2
  • 14
    • 13644268431 scopus 로고    scopus 로고
    • The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem.
    • Alvarez E, Martínez MD, Roncero I. The expression of GLP-1 receptor mRNA and protein allows the effect of GLP-1 on glucose metabolism in the human hypothalamus and brainstem. J Neurochem 2005, 92:798-806..
    • (2005) J Neurochem , vol.92
    • Alvarez, E.1    Martínez, M.D.2    Roncero, I.3
  • 15
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease.
    • Abbas T, Faivre E, Hölscher C. Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease. Behav Brain Res 2009, 205:265-271..
    • (2009) Behav Brain Res , vol.205
    • Abbas, T.1    Faivre, E.2    Hölscher, C.3
  • 16
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid.
    • Gault VA, Hölscher C. GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid. Eur J Pharmacol 2008, 587:112-117..
    • (2008) Eur J Pharmacol , vol.587
    • Gault, V.A.1    Hölscher, C.2
  • 17
    • 0027476024 scopus 로고
    • A synaptic model of memory: long-term potentiation in the hippocampus.
    • Bliss TV, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993, 361:31-39..
    • (1993) Nature , vol.361
    • Bliss, T.V.1    Collingridge, G.L.2
  • 18
    • 33745685529 scopus 로고    scopus 로고
    • Plasticity in the human central nervous system.
    • Cooke SF, Bliss TV. Plasticity in the human central nervous system. Brain 2006, 129:1659-1673..
    • (2006) Brain , vol.129
    • Cooke, S.F.1    Bliss, T.V.2
  • 19
    • 33947262557 scopus 로고    scopus 로고
    • Soluble beta-amyoid [25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning.
    • Hölscher C, Gengler S, Gault VA, Harriott P, Mallot HA. Soluble beta-amyoid [25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning. Eur J Pharmacol 2007, 56:85-90..
    • (2007) Eur J Pharmacol , vol.56
    • Hölscher, C.1    Gengler, S.2    Gault, V.A.3    Harriott, P.4    Mallot, H.A.5
  • 20
    • 34249024370 scopus 로고    scopus 로고
    • Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid [25-35] are dependent on stimulation-protocol and genetic background.
    • Gengler S, Gault VA, Harriott P, Hölscher C. Impairments of hippocampal synaptic plasticity induced by aggregated beta-amyloid [25-35] are dependent on stimulation-protocol and genetic background. Exp Brain Res 2007, 179:621-630..
    • (2007) Exp Brain Res , vol.179
    • Gengler, S.1    Gault, V.A.2    Harriott, P.3    Hölscher, C.4
  • 21
    • 0015038855 scopus 로고
    • Determination of glucose by an automated analyser.
    • Stevens JF. Determination of glucose by an automated analyser. Clin Chem Acta 1971, 32:199-201..
    • (1971) Clin Chem Acta , vol.32
    • Stevens, J.F.1
  • 22
    • 0019471997 scopus 로고
    • Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice.
    • Flatt PR, Bailey CJ. Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice. Diabetologia 1981, 20:573-577..
    • (1981) Diabetologia , vol.20
    • Flatt, P.R.1    Bailey, C.J.2
  • 23
    • 34247574175 scopus 로고    scopus 로고
    • The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents.
    • Dere E, Huston JP, De Souza Silva MA. The pharmacology, neuroanatomy and neurogenetics of one-trial object recognition in rodents. Neurosci Biobehav Rev 2007, 31:673-704..
    • (2007) Neurosci Biobehav Rev , vol.31
    • Dere, E.1    Huston, J.P.2    De Souza Silva, M.A.3
  • 24
    • 0343742511 scopus 로고    scopus 로고
    • Stimulation on the positive phase of hippocampal theta rhythm induces long-term potentiation which can be depotentiated by stimulation on the negative phase in area CA1 in vivo.
    • Hölscher C, Anwyl R, Rowan MJ. Stimulation on the positive phase of hippocampal theta rhythm induces long-term potentiation which can be depotentiated by stimulation on the negative phase in area CA1 in vivo. J Neurosci 1997, 17:6470-6477..
    • (1997) J Neurosci , vol.17
    • Hölscher, C.1    Anwyl, R.2    Rowan, M.J.3
  • 25
  • 27
    • 34447127048 scopus 로고    scopus 로고
    • Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose tolerance and associated disturbances in mice fed high-fat and cafeteria diets.
    • Gault VA, McClean PL, Cassidy RS, Irwin N, Flatt PR. Chemical gastric inhibitory polypeptide receptor antagonism protects against obesity, insulin resistance, glucose tolerance and associated disturbances in mice fed high-fat and cafeteria diets. Diabetologia 2007, 50:1752-1762..
    • (2007) Diabetologia , vol.50
    • Gault, V.A.1    McClean, P.L.2    Cassidy, R.S.3    Irwin, N.4    Flatt, P.R.5
  • 28
    • 0032010997 scopus 로고    scopus 로고
    • Effect of chronic central administration of glucagon-like peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats.
    • Davis HR, Mullins DE, Pines JM. Effect of chronic central administration of glucagon-like peptide-1 (7-36) amide on food consumption and body weight in normal and obese rats. Obes Res 1998, 6:147-156..
    • (1998) Obes Res , vol.6
    • Davis, H.R.1    Mullins, D.E.2    Pines, J.M.3
  • 29
    • 0035516188 scopus 로고    scopus 로고
    • Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats.
    • Larsen PJ, Fledelius C, Knudsen LB, Tang-Christensen M. Systemic administration of the long-acting GLP-1 derivative NN2211 induces lasting and reversible weight loss in both normal and obese rats. Diabetes 2001, 50:2530-2539..
    • (2001) Diabetes , vol.50
    • Larsen, P.J.1    Fledelius, C.2    Knudsen, L.B.3    Tang-Christensen, M.4
  • 30
    • 70349151817 scopus 로고    scopus 로고
    • Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signalling in obesity.
    • Ernst MB, Wunderlich CM, Hess S. Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signalling in obesity. J Neurosci 2009, 29:11582-11593..
    • (2009) J Neurosci , vol.29
    • Ernst, M.B.1    Wunderlich, C.M.2    Hess, S.3
  • 31
    • 0034333018 scopus 로고    scopus 로고
    • Cognition and synaptic plasticity in diabetes mellitus.
    • Gispen WH, Biessels GJ. Cognition and synaptic plasticity in diabetes mellitus. Trends Neurosci 2000, 23:542-549..
    • (2000) Trends Neurosci , vol.23
    • Gispen, W.H.1    Biessels, G.J.2
  • 32
    • 1842785174 scopus 로고    scopus 로고
    • Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus.
    • Trudeau F, Gagnon S, Massicotte G. Hippocampal synaptic plasticity and glutamate receptor regulation: influences of diabetes mellitus. Eur J Pharmacol 2004, 490:177-186..
    • (2004) Eur J Pharmacol , vol.490
    • Trudeau, F.1    Gagnon, S.2    Massicotte, G.3
  • 33
    • 1842734649 scopus 로고    scopus 로고
    • Modulation of memory by insulin and glucose: neuropsychologial observations in Alzheimer's disease.
    • Watson GS, Craft S. Modulation of memory by insulin and glucose: neuropsychologial observations in Alzheimer's disease. Eur J Pharmacol 2004, 490:97-113..
    • (2004) Eur J Pharmacol , vol.490
    • Watson, G.S.1    Craft, S.2
  • 34
    • 27844578300 scopus 로고    scopus 로고
    • Insulin and cognitive function in humans: experimental data and therapeutic considerations.
    • Strachan MW. Insulin and cognitive function in humans: experimental data and therapeutic considerations. Biochem Soc Trans 2005, 33:1037-1040..
    • (2005) Biochem Soc Trans , vol.33
    • Strachan, M.W.1
  • 35
    • 64249126355 scopus 로고    scopus 로고
    • The influences of juvenile diabetes on memory and hippocampal plasticity in rats: improving effects of glucagon-like peptide-1.
    • Iwai T, Suzuki M, Kobayashi K, Mori K, Mogi Y, Oka JI. The influences of juvenile diabetes on memory and hippocampal plasticity in rats: improving effects of glucagon-like peptide-1. Neurosci Res 2009, 64:67-74..
    • (2009) Neurosci Res , vol.64
    • Iwai, T.1    Suzuki, M.2    Kobayashi, K.3    Mori, K.4    Mogi, Y.5    Oka, J.I.6
  • 36
    • 23844470857 scopus 로고    scopus 로고
    • Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner.
    • van der Heide LP, Kamal A, Artola A, Gispen WH, Ramakers GM. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. J Neurosci 2005, 94:1158-1166..
    • (2005) J Neurosci , vol.94
    • van der Heide, L.P.1    Kamal, A.2    Artola, A.3    Gispen, W.H.4    Ramakers, G.M.5
  • 38
    • 36448936053 scopus 로고    scopus 로고
    • Common pathological processes in Alzheimer's disease and type 2 diabetes: a review.
    • Li L, Hölscher C. Common pathological processes in Alzheimer's disease and type 2 diabetes: a review. Brain Res Rev 2007, 56:384-402..
    • (2007) Brain Res Rev , vol.56
    • Li, L.1    Hölscher, C.2
  • 39
    • 76749116176 scopus 로고    scopus 로고
    • Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice.
    • D'Amico M, Di Filippo C, Marfella R. Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice. Exp Gerontol 2010, 45:202-207..
    • (2010) Exp Gerontol , vol.45
    • D'Amico, M.1    Di Filippo, C.2    Marfella, R.3
  • 40
    • 77955470617 scopus 로고    scopus 로고
    • Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet., (Lond)
    • Gault VA, Porter WD, Flatt PR, Holscher C. Int J Obes 2010, 34:1341-1344. Actions of exendin-4 therapy on cognitive function and hippocampal synaptic plasticity in mice fed a high-fat diet., (Lond)
    • (2010) Int J Obes , vol.34 , pp. 1341-1344
    • Gault, V.A.1    Porter, W.D.2    Flatt, P.R.3    Holscher, C.4
  • 41
    • 84878636551 scopus 로고    scopus 로고
    • Restitution of brain responses to food stimuli and feeding in Type 2 diabetes by GLP-1 receptor agonist exenatide.
    • Nathan Y, Lee S, Ashoor G. Restitution of brain responses to food stimuli and feeding in Type 2 diabetes by GLP-1 receptor agonist exenatide. Diabetic Med 2010, 27(Suppl. 1):2..
    • (2010) Diabetic Med , vol.27 , Issue.SUPPL. 1
    • Nathan, Y.1    Lee, S.2    Ashoor, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.