메뉴 건너뛰기




Volumn 1473, Issue , 2012, Pages 204-213

Effects of the glucagon-like polypeptide-1 analogue (Val8)GLP-1 on learning, progenitor cell proliferation and neurogenesis in the C57B/16 mouse brain

Author keywords

Alzheimer's disease; Cognition; Diabetes; Incretin; Insulin; Neurodegenerative disease; Neurogenesis

Indexed keywords

(VAL 8)GLUCAGON LIKE POLYPEPTIDE 1; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; UNCLASSIFIED DRUG; VALINE;

EID: 84865521108     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.07.029     Document Type: Article
Times cited : (34)

References (34)
  • 1
    • 69549138878 scopus 로고    scopus 로고
    • Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease
    • T. Abbas, E. Faivre, and C. Hlscher Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: interaction between type 2 diabetes and Alzheimer's disease Behav. Brain Res. 205 2009 265 271
    • (2009) Behav. Brain Res. , vol.205 , pp. 265-271
    • Abbas, T.1    Faivre, E.2    Hlscher, C.3
  • 4
    • 44149122563 scopus 로고    scopus 로고
    • GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
    • V.A. Gault, and C. Holscher GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid Eur. J. Pharmacol. 587 2008 112 117
    • (2008) Eur. J. Pharmacol. , vol.587 , pp. 112-117
    • Gault, V.A.1    Holscher, C.2
  • 5
    • 82755176046 scopus 로고    scopus 로고
    • Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice
    • S. Gengler, P. McClean, R. McCurtin, V. Gault, and C. Holscher Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice Neurobiol. Aging 33 2012 265 276
    • (2012) Neurobiol. Aging , vol.33 , pp. 265-276
    • Gengler, S.1    McClean, P.2    McCurtin, R.3    Gault, V.4    Holscher, C.5
  • 6
    • 33745937115 scopus 로고    scopus 로고
    • Novel GLP-1 analogue (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta cell function after 3 weeks daily administration in obese diabetic (ob/ob) mice
    • B.D. Green, K.S. Lavery, N. Irwin, F.P. O'Harte, P. Harriott, B. Greer, C.J. Bailey, and P.R. Flatt Novel GLP-1 analogue (Val8)GLP-1 results in significant improvements of glucose tolerance and pancreatic beta cell function after 3 weeks daily administration in obese diabetic (ob/ob) mice J. Pharmacol. Exp. Ther. 318 2006 914 921
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 914-921
    • Green, B.D.1    Lavery, K.S.2    Irwin, N.3    O'Harte, F.P.4    Harriott, P.5    Greer, B.6    Bailey, C.J.7    Flatt, P.R.8
  • 7
    • 33645882245 scopus 로고    scopus 로고
    • Neurodegeneration and neurogenesis: Focus on Alzheimer's disease
    • D.A. Greenberg, and K. Jin Neurodegeneration and neurogenesis: focus on Alzheimer's disease Curr. Alzheimer Res. 3 2006 25 28
    • (2006) Curr. Alzheimer Res. , vol.3 , pp. 25-28
    • Greenberg, D.A.1    Jin, K.2
  • 8
    • 79751479118 scopus 로고    scopus 로고
    • Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain
    • A. Hamilton, S. Patterson, D. Porter, V.A. Gault, and C. Holscher Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain J. Neurosci. Res. 89 2011 481 489
    • (2011) J. Neurosci. Res. , vol.89 , pp. 481-489
    • Hamilton, A.1    Patterson, S.2    Porter, D.3    Gault, V.A.4    Holscher, C.5
  • 9
    • 0026607117 scopus 로고
    • Hyperactivity, hyper-reactivity, and sensimotor deficits induced by low doses of the N-methyl-d-aspartate non-competitive channel blocker MK801
    • E.L. Hargreaves, and D.P. Cain Hyperactivity, hyper-reactivity, and sensimotor deficits induced by low doses of the N-methyl-d-aspartate non-competitive channel blocker MK801 Behav. Brain Res. 47 1992 23 33
    • (1992) Behav. Brain Res. , vol.47 , pp. 23-33
    • Hargreaves, E.L.1    Cain, D.P.2
  • 10
    • 45549108268 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease
    • A. Harkavyi, A. Abuirmeileh, R. Lever, A.E. Kingsbury, C.S. Biggs, and P.S. Whitton Glucagon-like peptide 1 receptor stimulation reverses key deficits in distinct rodent models of Parkinson's disease J. Neuroinflammation 5 2008 19
    • (2008) J. Neuroinflammation , vol.5 , pp. 19
    • Harkavyi, A.1    Abuirmeileh, A.2    Lever, R.3    Kingsbury, A.E.4    Biggs, C.S.5    Whitton, P.S.6
  • 12
    • 79960881826 scopus 로고    scopus 로고
    • Diabetes as a risk factor for Alzheimer's disease: Insulin signalling impairment in the brain as an alternative model of Alzheimer's disease
    • C. Holscher Diabetes as a risk factor for Alzheimer's disease: insulin signalling impairment in the brain as an alternative model of Alzheimer's disease Biochem. Soc. Trans. 39 2011 891 897
    • (2011) Biochem. Soc. Trans. , vol.39 , pp. 891-897
    • Holscher, C.1
  • 13
    • 0030297441 scopus 로고    scopus 로고
    • L-AP4 (l-()-2-amino-4-phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2-methy l-4-phosphonobutanoic acid)
    • C. Hlscher, L. McGlinchey, and M.J. Rowan l-AP4 (l-()-2-amino-4- phosphonobutyric acid) induced impairment of spatial learning in the rat is antagonized by MAP4 ((S)-2-amino-2-methy l-4-phosphonobutanoic acid) Behav. Brain Res. 81 1996 69 79
    • (1996) Behav. Brain Res. , vol.81 , pp. 69-79
    • Hlscher, C.1    McGlinchey, L.2    Rowan, M.J.3
  • 14
    • 2642519637 scopus 로고    scopus 로고
    • Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors
    • J.J. Holst Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors Expert Opin. Emerg. Drugs 9 2004 155 166
    • (2004) Expert Opin. Emerg. Drugs , vol.9 , pp. 155-166
    • Holst, J.J.1
  • 15
    • 84858713174 scopus 로고    scopus 로고
    • Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis
    • K. Hunter, and C. Holscher Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis BMC Neurosci. 13 2012 33 38
    • (2012) BMC Neurosci. , vol.13 , pp. 33-38
    • Hunter, K.1    Holscher, C.2
  • 16
    • 79955608846 scopus 로고    scopus 로고
    • Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia
    • C. Hyun Lee, B. Yan, K.Y. Yoo, J.H. Choi, S.H. Kwon, S. Her, Y. Sohn, I.K. Hwang, J.H. Cho, Y.M. Kim, and M.H. Won Ischemia-induced changes in glucagon-like peptide-1 receptor and neuroprotective effect of its agonist, exendin-4, in experimental transient cerebral ischemia J. Neurosci. Res. 89 2011 1103 1113
    • (2011) J. Neurosci. Res. , vol.89 , pp. 1103-1113
    • Hyun Lee, C.1    Yan, B.2    Yoo, K.Y.3    Choi, J.H.4    Kwon, S.H.5    Her, S.6    Sohn, Y.7    Hwang, I.K.8    Cho, J.H.9    Kim, Y.M.10    Won, M.H.11
  • 17
    • 0036198285 scopus 로고    scopus 로고
    • Interactions of glucagon-like peptide-1 (GLP-1) with the bloodbrain barrier
    • A.J. Kastin, V. Akerstrom, and W. Pan Interactions of glucagon-like peptide-1 (GLP-1) with the bloodbrain barrier J. Mol. Neurosci. 18 2002 7 14
    • (2002) J. Mol. Neurosci. , vol.18 , pp. 7-14
    • Kastin, A.J.1    Akerstrom, V.2    Pan, W.3
  • 18
    • 0037349072 scopus 로고    scopus 로고
    • Entry of exendin-4 into brain is rapid but may be limited at high doses
    • A.J. Kastin, and V. Akerstrom Entry of exendin-4 into brain is rapid but may be limited at high doses Int. J. Obes. Relat. Metab. Disord. 27 2003 313 318
    • (2003) Int. J. Obes. Relat. Metab. Disord. , vol.27 , pp. 313-318
    • Kastin, A.J.1    Akerstrom, V.2
  • 19
    • 79751472143 scopus 로고    scopus 로고
    • Chronic treatment of exendin-4 affects cell proliferation and neuroblast differentiation in the adult mouse Hippocampal dentate gyrus
    • H. Li, C.H. Lee, K.Y. Yoo, J.H. Choi, O.K. Park, B.C. Yan, K. Byun, B. Lee, I.K. Hwang, and M.H. Won Chronic treatment of exendin-4 affects cell proliferation and neuroblast differentiation in the adult mouse Hippocampal dentate gyrus Neurosci. Lett. 19 2010 1205 1219
    • (2010) Neurosci. Lett. , vol.19 , pp. 1205-1219
    • Li, H.1    Lee, C.H.2    Yoo, K.Y.3    Choi, J.H.4    Park, O.K.5    Yan, B.C.6    Byun, K.7    Lee, B.8    Hwang, I.K.9    Won, M.H.10
  • 20
    • 84865456155 scopus 로고    scopus 로고
    • (Val(8)) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains
    • L. Li, Z.F. Zhang, C. Holscher, C. Gao, Y.H. Jiang, and Y.Z. Liu (Val(8)) glucagon-like peptide-1 prevents tau hyperphosphorylation, impairment of spatial learning and ultra-structural cellular damage induced by streptozotocin in rat brains Eur. J. Pharmacol 2011
    • (2011) Eur. J. Pharmacol
    • Li, L.1    Zhang, Z.F.2    Holscher, C.3    Gao, C.4    Jiang, Y.H.5    Liu, Y.Z.6
  • 22
    • 77953726744 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 protects NSC-34 motor neurons against glucosamine through Epac-mediated glucose uptake enhancement
    • J.G. Lim, J.J. Lee, S.H. Park, J.H. Park, S.J. Kim, H.C. Cho, W.K. Baek, D.K. Kim, and D.K. Song Glucagon-like peptide-1 protects NSC-34 motor neurons against glucosamine through Epac-mediated glucose uptake enhancement Neurosci. Lett. 479 2010 13 17
    • (2010) Neurosci. Lett. , vol.479 , pp. 13-17
    • Lim, J.G.1    Lee, J.J.2    Park, S.H.3    Park, J.H.4    Kim, S.J.5    Cho, H.C.6    Baek, W.K.7    Kim, D.K.8    Song, D.K.9
  • 23
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus
    • J.A. Lovshin, and D.J. Drucker Incretin-based therapies for type 2 diabetes mellitus Nat. Rev. Endocrinol. 5 2009 262 269
    • (2009) Nat. Rev. Endocrinol. , vol.5 , pp. 262-269
    • Lovshin, J.A.1    Drucker, D.J.2
  • 24
    • 5344256250 scopus 로고    scopus 로고
    • Hyperinsulinemia and risk of Alzheimer disease
    • J.A. Luchsinger, M.X. Tang, S. Shea, and R. Mayeux Hyperinsulinemia and risk of Alzheimer disease Neurology 63 2004 1187 1192
    • (2004) Neurology , vol.63 , pp. 1187-1192
    • Luchsinger, J.A.1    Tang, M.X.2    Shea, S.3    Mayeux, R.4
  • 25
    • 79955749452 scopus 로고    scopus 로고
    • The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease
    • P. McClean, V. Parthsarathy, E. Faivre, and C. Hlscher The diabetes drug Liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease J. Neurosci. 31 2011 6587 6594
    • (2011) J. Neurosci. , vol.31 , pp. 6587-6594
    • McClean, P.1    Parthsarathy, V.2    Faivre, E.3    Hlscher, C.4
  • 26
    • 71349085957 scopus 로고    scopus 로고
    • Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
    • A.M. Moloney, R.J. Griffin, S. Timmons, R. O'Connor, R. Ravid, and C. O'Neill Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling Neurobiol. Aging 31 2010 224 243
    • (2010) Neurobiol. Aging , vol.31 , pp. 224-243
    • Moloney, A.M.1    Griffin, R.J.2    Timmons, S.3    O'Connor, R.4    Ravid, R.5    O'Neill, C.6
  • 28
    • 0036182251 scopus 로고    scopus 로고
    • A novel neurotrophic property of glucagon-like peptide 1: A promoter of nerve growth factor-mediated differentiation in PC12 cells
    • T. Perry, D.K. Lahiri, D. Chen, J. Zhou, K.T. Shaw, J.M. Egan, and N.H. Greig A novel neurotrophic property of glucagon-like peptide 1: a promoter of nerve growth factor-mediated differentiation in PC12 cells J. Pharmacol. Exp. Ther. 300 2002 958 966
    • (2002) J. Pharmacol. Exp. Ther. , vol.300 , pp. 958-966
    • Perry, T.1    Lahiri, D.K.2    Chen, D.3    Zhou, J.4    Shaw, K.T.5    Egan, J.M.6    Greig, N.H.7
  • 29
    • 33846501672 scopus 로고    scopus 로고
    • Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy
    • T. Perry, H.W. Holloway, A. Weerasuriya, P.R. Mouton, K. Duffy, J.A. Mattison, and N.H. Greig Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy Exp. Neurol. 203 2007 293 301
    • (2007) Exp. Neurol. , vol.203 , pp. 293-301
    • Perry, T.1    Holloway, H.W.2    Weerasuriya, A.3    Mouton, P.R.4    Duffy, K.5    Mattison, J.A.6    Greig, N.H.7
  • 31
    • 0036035521 scopus 로고    scopus 로고
    • Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans
    • A. Vella, P. Shah, A.S. Reed, A.S. Adkins, R. Basu, and R.A. Rizza Lack of effect of exendin-4 and glucagon-like peptide-1-(7,36)-amide on insulin action in non-diabetic humans Diabetologia 45 2002 1410 1415
    • (2002) Diabetologia , vol.45 , pp. 1410-1415
    • Vella, A.1    Shah, P.2    Reed, A.S.3    Adkins, A.S.4    Basu, R.5    Rizza, R.A.6
  • 32
    • 77956301808 scopus 로고    scopus 로고
    • Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: Role of peripherally secreted and centrally produced peptides
    • N. Vrang, and P.J. Larsen Preproglucagon derived peptides GLP-1, GLP-2 and oxyntomodulin in the CNS: role of peripherally secreted and centrally produced peptides Prog. Neurobiol. 92 2010 442 462
    • (2010) Prog. Neurobiol. , vol.92 , pp. 442-462
    • Vrang, N.1    Larsen, P.J.2
  • 33
    • 77957126457 scopus 로고    scopus 로고
    • Val8-glucagon-like peptide-1 protects against Abeta1-40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats
    • X.H. Wang, L. Li, C. Holscher, Y.F. Pan, X.R. Chen, and J.S. Qi Val8-glucagon-like peptide-1 protects against Abeta1-40-induced impairment of hippocampal late-phase long-term potentiation and spatial learning in rats Neuroscience 170 2010 1239 1248
    • (2010) Neuroscience , vol.170 , pp. 1239-1248
    • Wang, X.H.1    Li, L.2    Holscher, C.3    Pan, Y.F.4    Chen, X.R.5    Qi, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.