-
1
-
-
79955407461
-
Towards a synthetic chloroplast
-
Agapakis CM, Niederholtmeyer H, Noche RR, Lieberman TD, Megason SG, Way JC, Silver PA. 2011. Towards a synthetic chloroplast. PLoS ONE 6: e18877.
-
(2011)
PLoS ONE
, vol.6
-
-
Agapakis, C.M.1
Niederholtmeyer, H.2
Noche, R.R.3
Lieberman, T.D.4
Megason, S.G.5
Way, J.C.6
Silver, P.A.7
-
2
-
-
34548856538
-
Rational design of memory in eukaryotic cells
-
Ajo-Franklin CM, Drubin DA, Eskin JA, Gee EPS, Landgraf D, Phillips I, Silver PA. 2007. Rational design of memory in eukaryotic cells. Genes Dev 21: 2271-2276.
-
(2007)
Genes Dev
, vol.21
, pp. 2271-2276
-
-
Ajo-Franklin, C.M.1
Drubin, D.A.2
Eskin, J.A.3
Gee, E.P.S.4
Landgraf, D.5
Phillips, I.6
Silver, P.A.7
-
3
-
-
29144482539
-
Environmentally controlled invasion of cancer cells by engineered bacteria
-
Anderson JC, Clarke EJ, Arkin AP, Voigt CA. 2006. Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol 355: 619-627.
-
(2006)
J Mol Biol
, vol.355
, pp. 619-627
-
-
Anderson, J.C.1
Clarke, E.J.2
Arkin, A.P.3
Voigt, C.A.4
-
4
-
-
34547916832
-
Environmental signal integration by a modular AND gate
-
Anderson JC, Voigt CA, Arkin AP. 2007. Environmental signal integration by a modular AND gate. Mol Syst Biol 3: 133.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 133
-
-
Anderson, J.C.1
Voigt, C.A.2
Arkin, A.P.3
-
5
-
-
84859771131
-
Smart medication through combination of synthetic biology and cell microencapsulation
-
doi: 10.1016/j.ymben.2011.06.003.
-
Ausländer S, Wieland M, Fussenegger M. 2011. Smart medication through combination of synthetic biology and cell microencapsulation. Metab Eng doi: 10.1016/j.ymben.2011.06.003.
-
(2011)
Metab Eng
-
-
Ausländer, S.1
Wieland, M.2
Fussenegger, M.3
-
6
-
-
42749092251
-
Insulin-secreting L-cells for the treatment of insulin-dependent diabetes
-
Bara H, Sambanis A. 2008. Insulin-secreting L-cells for the treatment of insulin-dependent diabetes. Biochem Biophys Res Commun 371: 39-43.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 39-43
-
-
Bara, H.1
Sambanis, A.2
-
7
-
-
21444457242
-
Programmable ligand-controlled riboregulators of eukaryotic gene expression
-
Bayer TS, Smolke CD. 2005. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat Biotechnol 23: 337-343.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 337-343
-
-
Bayer, T.S.1
Smolke, C.D.2
-
8
-
-
54949106632
-
Modelguided design of ligand-regulated RNAi for programmable control of gene expression
-
Beisel CL, Bayer TS, Hoff KG, Smolke CD. 2008. Modelguided design of ligand-regulated RNAi for programmable control of gene expression. Mol Syst Biol 4: 224.
-
(2008)
Mol Syst Biol
, vol.4
, pp. 224
-
-
Beisel, C.L.1
Bayer, T.S.2
Hoff, K.G.3
Smolke, C.D.4
-
9
-
-
34247492871
-
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors
-
Beltran A, Parikh S, Liu Y, Cuevas BD, Johnson GL, Futscher BW, Blancafort P. 2007. Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors. Oncogene 26: 2791-2798.
-
(2007)
Oncogene
, vol.26
, pp. 2791-2798
-
-
Beltran, A.1
Parikh, S.2
Liu, Y.3
Cuevas, B.D.4
Johnson, G.L.5
Futscher, B.W.6
Blancafort, P.7
-
10
-
-
27944464545
-
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus
-
Berk AJ. 2005. Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene 24: 7673-7685.
-
(2005)
Oncogene
, vol.24
, pp. 7673-7685
-
-
Berk, A.J.1
-
11
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, et al. 2010. The landscape of somatic copy-number alteration across human cancers. Nature 463: 899-905.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
Wei, G.4
Raychaudhuri, S.5
Donovan, J.6
Barretina, J.7
Boehm, J.S.8
Dobson, J.9
Urashima, M.10
-
12
-
-
67650671869
-
Harnessing nature's toolbox: Regulatory elements for synthetic biology
-
Boyle PM, Silver PA. 2009. Harnessing nature's toolbox: Regulatory elements for synthetic biology. J R Soc Interface 6 (Suppl 4): S535-S546.
-
(2009)
J R Soc Interface
, vol.6
, Issue.SUPPL. 4
-
-
Boyle, P.M.1
Silver, P.A.2
-
13
-
-
0027465481
-
A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins
-
Braselmann S, Graninger P, Busslinger M. 1993. A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins. Proc Natl Acad Sci 90: 1657-1661.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 1657-1661
-
-
Braselmann, S.1
Graninger, P.2
Busslinger, M.3
-
14
-
-
33644832381
-
In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production
-
Bro C, Regenberg B, Förster J, Nielsen J. 2006. In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. Metab Eng 8: 102-111.
-
(2006)
Metab Eng
, vol.8
, pp. 102-111
-
-
Bro, C.1
Regenberg, B.2
Förster, J.3
Nielsen, J.4
-
15
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
Bubber P, Haroutunian V, Fisch G, Blass JP, Gibson GE. 2005. Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications. Ann Neurol 57: 695-703.
-
(2005)
Ann Neurol
, vol.57
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
16
-
-
0242487787
-
Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
-
Burgard AP, Pharkya P, Maranas CD. 2003. Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization. Biotechnol Bioeng 84: 647-657.
-
(2003)
Biotechnol Bioeng
, vol.84
, pp. 647-657
-
-
Burgard, A.P.1
Pharkya, P.2
Maranas, C.D.3
-
17
-
-
73149084398
-
Making cellular memories
-
Burrill DR, Silver PA. 2010. Making cellular memories. Cell 140: 13-18.
-
(2010)
Cell
, vol.140
, pp. 13-18
-
-
Burrill, D.R.1
Silver, P.A.2
-
18
-
-
79952214973
-
Synthetic circuit identifies subpopulations with sustained memory of DNA damage
-
Burrill DR, Silver PA. 2011. Synthetic circuit identifies subpopulations with sustained memory of DNA damage. Genes Dev 25: 434-439.
-
(2011)
Genes Dev
, vol.25
, pp. 434-439
-
-
Burrill, D.R.1
Silver, P.A.2
-
19
-
-
43749102294
-
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand
-
Cironi P, Swinburne IA, Silver PA. 2008. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J Biol Chem 283: 8469-8476.
-
(2008)
J Biol Chem
, vol.283
, pp. 8469-8476
-
-
Cironi, P.1
Swinburne, I.A.2
Silver, P.A.3
-
20
-
-
78649429678
-
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins
-
Culler SJ, Hoff KG, Smolke CD. 2010. Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins. Science 330: 1251-1255.
-
(2010)
Science
, vol.330
, pp. 1251-1255
-
-
Culler, S.J.1
Hoff, K.G.2
Smolke, C.D.3
-
21
-
-
66049143446
-
Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt
-
Dean JT, Tran L, Beaven S, Tontonoz P, Reue K, Dipple KM, Liao JC. 2009. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab 9: 525-536.
-
(2009)
Cell Metab
, vol.9
, pp. 525-536
-
-
Dean, J.T.1
Tran, L.2
Beaven, S.3
Tontonoz, P.4
Reue, K.5
Dipple, K.M.6
Liao, J.C.7
-
22
-
-
34447505900
-
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells
-
Deans TL, Cantor CR, Collins JJ. 2007. A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell 130: 363-372.
-
(2007)
Cell
, vol.130
, pp. 363-372
-
-
Deans, T.L.1
Cantor, C.R.2
Collins, J.J.3
-
23
-
-
23144432213
-
Optimality and evolutionary tuning of the expression level of a protein
-
Dekel E, Alon U. 2005. Optimality and evolutionary tuning of the expression level of a protein. Nature 436: 588-592.
-
(2005)
Nature
, vol.436
, pp. 588-592
-
-
Dekel, E.1
Alon, U.2
-
24
-
-
80052321503
-
Introduction to gene therapy: A clinical aftermath
-
Denèfle PP. 2011. Introduction to gene therapy: A clinical aftermath. Meth Mol Biol 737: 27-44.
-
(2011)
Meth Mol Biol
, vol.737
, pp. 27-44
-
-
Denèfle, P.P.1
-
25
-
-
77954920911
-
Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model
-
Duan F, March JC. 2010. Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model. Proc Natl Acad Sci 107: 11260-11264.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 11260-11264
-
-
Duan, F.1
March, J.C.2
-
26
-
-
57149095846
-
Secretion of insulinotropic proteins by commensal bacteria: Rewiring the gut to treat diabetes
-
Duan F, Curtis KL, March JC. 2008. Secretion of insulinotropic proteins by commensal bacteria: Rewiring the gut to treat diabetes. Appl Environ Microbiol 74: 7437-7438.
-
(2008)
Appl Environ Microbiol
, vol.74
, pp. 7437-7438
-
-
Duan, F.1
Curtis, K.L.2
March, J.C.3
-
27
-
-
3843128481
-
Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model
-
Duarte NC, Herrga°rd MJ, Palsson BO. 2004. Reconstruction and validation of Saccharomyces cerevisiae iND750, a fully compartmentalized genome-scale metabolic model. Genome Res 14: 1298-1309.
-
(2004)
Genome Res
, vol.14
, pp. 1298-1309
-
-
Duarte, N.C.1
Herrga°rd, M.J.2
Palsson, B.O.3
-
28
-
-
33846910173
-
Global reconstruction of the human metabolic network based on genomic and bibliomic data
-
Duarte NC, Becker SA, Jamshidi N, Thiele I, Mo ML, Vo TD, Srivas R, Palsson BO. 2007. Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc Natl Acad Sci 104: 1777-1782.
-
(2007)
Proc Natl Acad Sci
, vol.104
, pp. 1777-1782
-
-
Duarte, N.C.1
Becker, S.A.2
Jamshidi, N.3
Thiele, I.4
Mo, M.L.5
Vo, T.D.6
Srivas, R.7
Palsson, B.O.8
-
29
-
-
0036001069
-
Metabolic modelling of microbes: The flux-balance approach
-
Edwards JS, Covert M, Palsson B. 2002. Metabolic modelling of microbes: The flux-balance approach. Environ Microbiol 4: 133-140.
-
(2002)
Environ Microbiol
, vol.4
, pp. 133-140
-
-
Edwards, J.S.1
Covert, M.2
Palsson, B.3
-
32
-
-
66349125024
-
Synthetic gene networks that count
-
Friedland AE, Lu TK, Wang X, Shi D, Church G, Collins JJ. 2009. Synthetic gene networks that count. Science 324: 1199-1202.
-
(2009)
Science
, vol.324
, pp. 1199-1202
-
-
Friedland, A.E.1
Lu, T.K.2
Wang, X.3
Shi, D.4
Church, G.5
Collins, J.J.6
-
33
-
-
80052261503
-
Managing risk in developing transplant immunosuppressive agents: The new regulatory environment
-
Gabardi S, Halloran PF, Friedewald J. 2011. Managing risk in developing transplant immunosuppressive agents: The new regulatory environment. Am J Transplant 11: 1803-1809.
-
(2011)
Am J Transplant
, vol.11
, pp. 1803-1809
-
-
Gabardi, S.1
Halloran, P.F.2
Friedewald, J.3
-
35
-
-
52649173346
-
Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch
-
Greber D, El-Baba MD, Fussenegger M. 2008. Intronically encoded siRNAs improve dynamic range of mammalian gene regulation systems and toggle switch. Nucl Acids Res 36: e101.
-
(2008)
Nucl Acids Res
, vol.36
-
-
Greber, D.1
El-Baba, M.D.2
Fussenegger, M.3
-
36
-
-
55549103314
-
A model for transmission of the H3K27me3 epigenetic mark
-
Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, Rappsilber J, Lerdrup M, Helin K. 2008. A model for transmission of the H3K27me3 epigenetic mark. Nature 10: 1291-1300.
-
(2008)
Nature
, vol.10
, pp. 1291-1300
-
-
Hansen, K.H.1
Bracken, A.P.2
Pasini, D.3
Dietrich, N.4
Gehani, S.S.5
Monrad, A.6
Rappsilber, J.7
Lerdrup, M.8
Helin, K.9
-
37
-
-
74049088689
-
Eukaryotic systems broaden the scope of synthetic biology
-
Haynes KA, Silver PA. 2009. Eukaryotic systems broaden the scope of synthetic biology. J Cell Biol 187: 589-596.
-
(2009)
J Cell Biol
, vol.187
, pp. 589-596
-
-
Haynes, K.A.1
Silver, P.A.2
-
38
-
-
79961005102
-
Synthetic reversal of epigenetic silencing
-
Haynes KA, Silver PA. 2011. Synthetic reversal of epigenetic silencing. J Biol Chem 286: 27176-27182.
-
(2011)
J Biol Chem
, vol.286
, pp. 27176-27182
-
-
Haynes, K.A.1
Silver, P.A.2
-
39
-
-
77951891440
-
pcDNA3.1(2)-mediated ribozyme targeting of HER-2 suppresses breast cancer tumor growth
-
He P, Zhu D, Hu J-J, Peng J, Chen L-S, Lu G-X. 2010. pcDNA3.1(2)-mediated ribozyme targeting of HER-2 suppresses breast cancer tumor growth. Mol Biol Rep 37: 1597-1604.
-
(2010)
Mol Biol Rep
, vol.37
, pp. 1597-1604
-
-
He, P.1
Zhu, D.2
Hu, J.-J.3
Peng, J.4
Chen, L.-S.5
Lu, G.-X.6
-
40
-
-
0037079023
-
Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth
-
Ibarra RU, Edwards JS, Palsson BO. 2002. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature 420: 186-189.
-
(2002)
Nature
, vol.420
, pp. 186-189
-
-
Ibarra, R.U.1
Edwards, J.S.2
Palsson, B.O.3
-
41
-
-
77956417789
-
Computational reconstruction of tissue-specific metabolic models: Application to human liver metabolism
-
Jerby L, Shlomi T, Ruppin E. 2010. Computational reconstruction of tissue-specific metabolic models: Application to human liver metabolism. Mol Syst Biol 6: 401.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 401
-
-
Jerby, L.1
Shlomi, T.2
Ruppin, E.3
-
42
-
-
70350443611
-
Systems-level engineering of nonfermentative metabolism in yeast
-
Kennedy CJ, Boyle PM, Waks Z, Silver PA. 2009. Systems-level engineering of nonfermentative metabolism in yeast. Genetics 183: 385-397.
-
(2009)
Genetics
, vol.183
, pp. 385-397
-
-
Kennedy, C.J.1
Boyle, P.M.2
Waks, Z.3
Silver, P.A.4
-
43
-
-
77951107086
-
Synthetic biology: Applications come of age
-
Khalil AS, Collins JJ. 2010. Synthetic biology: Applications come of age. Nat Rev Genet 11: 367-379.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
44
-
-
80054955393
-
Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus
-
Lagenaur LA, Sanders-Beer BE, Brichacek B, Pal R, Liu X, Liu Y, Yu R, Venzon D, Lee PP, Hamer DH. 2011. Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus. Mucosal Immunol 4: 648-657.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 648-657
-
-
Lagenaur, L.A.1
Sanders-Beer, B.E.2
Brichacek, B.3
Pal, R.4
Liu, X.5
Liu, Y.6
Yu, R.7
Venzon, D.8
Lee, P.P.9
Hamer, D.H.10
-
45
-
-
35448996504
-
Immunomodulation by mesenchymal stem cells and clinical experience
-
Le Blanc K, Ringdèn O. 2007. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 262: 509-525.
-
(2007)
J Intern Med
, vol.262
, pp. 509-525
-
-
Le Blanc, K.1
Ringdèn, O.2
-
46
-
-
78650002545
-
Large-scale in silico modeling of metabolic interactions between cell types in the human brain
-
Lewis NE, Schramm G, Bordbar A, Schellenberger J, Andersen MP, Cheng JK, Patel N, Yee A, Lewis RA, Eils R, et al. 2010. Large-scale in silico modeling of metabolic interactions between cell types in the human brain. Nat Biotechnol 28: 1279-1285.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1279-1285
-
-
Lewis, N.E.1
Schramm, G.2
Bordbar, A.3
Schellenberger, J.4
Andersen, M.P.5
Cheng, J.K.6
Patel, N.7
Yee, A.8
Lewis, R.A.9
Eils, R.10
-
47
-
-
79959268547
-
The implications of relationships between human diseases and metabolic subpathways
-
Li X, Li C, Shang D, Li J, Han J, Miao Y, Wang Y, Wang Q, Li W, Wu C, et al. 2011. The implications of relationships between human diseases and metabolic subpathways. PLoS ONE 6: e21131.
-
(2011)
PLoS ONE
, vol.6
-
-
Li, X.1
Li, C.2
Shang, D.3
Li, J.4
Han, J.5
Miao, Y.6
Wang, Y.7
Wang, Q.8
Li, W.9
Wu, C.10
-
48
-
-
33749532310
-
Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N
-
Liu X, Lagenaur LA, Simpson DA, Essenmacher KP, Frazier-Parker CL, Liu Y, Tsai D, Rao SS, Hamer DH, Parks TP, et al. 2006. Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N. Antimicrob Agents Chemother 50: 3250-3259.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 3250-3259
-
-
Liu, X.1
Lagenaur, L.A.2
Simpson, D.A.3
Essenmacher, K.P.4
Frazier-Parker, C.L.5
Liu, Y.6
Tsai, D.7
Rao, S.S.8
Hamer, D.H.9
Parks, T.P.10
-
49
-
-
0033579358
-
Clinical Trials: Gene therapy death prompts review of adenovirus vector
-
Marshall E. 1999. Clinical Trials: Gene therapy death prompts review of adenovirus vector. Science 286: 2244-2245.
-
(1999)
Science
, vol.286
, pp. 2244-2245
-
-
Marshall, E.1
-
50
-
-
77956651992
-
Systems biology of the gut: The interplay of food, microbiota and host at the mucosal interface
-
Martins Dos Santos V, Müller M, de Vos WM. 2010. Systems biology of the gut: The interplay of food, microbiota and host at the mucosal interface. Curr Opin Biotechnol 21: 539-550.
-
(2010)
Curr Opin Biotechnol
, vol.21
, pp. 539-550
-
-
Martins Dos Santos, V.1
Müller, M.2
de Vos, W.M.3
-
51
-
-
65249167505
-
DNA binding site sequence directs glucocorticoid receptor structure and activity
-
Meijsing SH, Pufall MA, So AY, Bates DL, Chen L, Yamamoto KR. 2009. DNA binding site sequence directs glucocorticoid receptor structure and activity. Science 324: 407-410.
-
(2009)
Science
, vol.324
, pp. 407-410
-
-
Meijsing, S.H.1
Pufall, M.A.2
So, A.Y.3
Bates, D.L.4
Chen, L.5
Yamamoto, K.R.6
-
52
-
-
78149361554
-
Metabolic control analysis indicates a change of strategy in the treatment of cancer
-
Moreno-Sànchez R, Saavedra E, Rodrìguez-Enrìquez S, Gallardo-Pèrez JC, Quezada H, Westerhoff HV. 2010. Metabolic control analysis indicates a change of strategy in the treatment of cancer. Mitochondrion 10: 626-639.
-
(2010)
Mitochondrion
, vol.10
, pp. 626-639
-
-
Moreno-Sànchez, R.1
Saavedra, E.2
Rodrìguez-Enrìquez, S.3
Gallardo-Pèrez, J.C.4
Quezada, H.5
Westerhoff, H.V.6
-
53
-
-
77954079519
-
Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways
-
Mulhbacher J, Brouillette E, Allard M, Fortier L-C, Malouin F, Lafontaine DA. 2010. Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. PLoS Pathog 6: e1000865.
-
(2010)
PLoS Pathog
, vol.6
-
-
Mulhbacher, J.1
Brouillette, E.2
Allard, M.3
Fortier, L.-C.4
Malouin, F.5
Lafontaine, D.A.6
-
54
-
-
14744303077
-
Cellular engineering for the treatment of metabolic disorders: Prospects for therapy in diabetes
-
Newgard CB. 1992. Cellular engineering for the treatment of metabolic disorders: Prospects for therapy in diabetes. Biotechnology (NY) 10: 1112-1120.
-
(1992)
Biotechnology (NY)
, vol.10
, pp. 1112-1120
-
-
Newgard, C.B.1
-
56
-
-
53249113140
-
A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals
-
Ohno K, Ishihata K, Tanaka-Azuma Y, Yamada T. 2008. A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals. Mutat Res 656: 27-35.
-
(2008)
Mutat Res
, vol.656
, pp. 27-35
-
-
Ohno, K.1
Ishihata, K.2
Tanaka-Azuma, Y.3
Yamada, T.4
-
57
-
-
79751505371
-
Fecal matters
-
Palmer R. 2011. Fecal matters. Nat Med 17: 150-152.
-
(2011)
Nat Med
, vol.17
, pp. 150-152
-
-
Palmer, R.1
-
58
-
-
8744224466
-
OptStrain: A computational framework for redesign of microbial production systems
-
Pharkya P, Burgard AP, Maranas CD. 2004. OptStrain: A computational framework for redesign of microbial production systems. Genome Res 14: 2367-2376.
-
(2004)
Genome Res
, vol.14
, pp. 2367-2376
-
-
Pharkya, P.1
Burgard, A.P.2
Maranas, C.D.3
-
59
-
-
77950251400
-
A human gut microbial gene catalogue established by metagenomic sequencing
-
Qin J, Li R, Raes J, Arumugam M, Burgdorf KS, Manichanh C, Nielsen T, Pons N, Levenez F, Yamada T, et al. 2010. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464: 59-65.
-
(2010)
Nature
, vol.464
, pp. 59-65
-
-
Qin, J.1
Li, R.2
Raes, J.3
Arumugam, M.4
Burgdorf, K.S.5
Manichanh, C.6
Nielsen, T.7
Pons, N.8
Levenez, F.9
Yamada, T.10
-
60
-
-
24644446235
-
Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide
-
Rao S, Hu S, McHugh L, Lueders K, Henry K, Zhao Q, Fekete RA, Kar S, Adhya S, Hamer DH. 2005. Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide. Proc Natl Acad Sci 102: 11993-11998.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 11993-11998
-
-
Rao, S.1
Hu, S.2
McHugh, L.3
Lueders, K.4
Henry, K.5
Zhao, Q.6
Fekete, R.A.7
Kar, S.8
Adhya, S.9
Hamer, D.H.10
-
61
-
-
0033564230
-
How aneuploidy affects metabolic control and causes cancer
-
Rasnick D, Duesberg PH. 1999. How aneuploidy affects metabolic control and causes cancer. Biochem J 340 (Pt 3): 621-630.
-
(1999)
Biochem J
, vol.340
, Issue.PART 3
, pp. 621-630
-
-
Rasnick, D.1
Duesberg, P.H.2
-
62
-
-
34447310821
-
A universal RNAi-based logic evaluator that operates in mammalian cells
-
Rinaudo K, Bleris L, Maddamsetti R, Subramanian S, Weiss R, Benenson Y. 2007. A universal RNAi-based logic evaluator that operates in mammalian cells. Nat Biotechnol 25: 795-801.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 795-801
-
-
Rinaudo, K.1
Bleris, L.2
Maddamsetti, R.3
Subramanian, S.4
Weiss, R.5
Benenson, Y.6
-
63
-
-
77950960250
-
OptFlux: An open-source software platform for in silico metabolic engineering
-
Rocha I, Maia P, Evangelista P, Vilaca P, Soares S, Pinto JP, Nielsen J, Patil KR, Ferreira EC, Rocha M. 2010. OptFlux: An open-source software platform for in silico metabolic engineering. BMC Syst Biol 4: 45.
-
(2010)
BMC Syst Biol
, vol.4
, pp. 45
-
-
Rocha, I.1
Maia, P.2
Evangelista, P.3
Vilaca, P.4
Soares, S.5
Pinto, J.P.6
Nielsen, J.7
Patil, K.R.8
Ferreira, E.C.9
Rocha, M.10
-
64
-
-
84934438895
-
Systems biology approaches and tools for analysis of interactomes and multitarget drugs
-
Schrattenholz A, Groebe K, Soskic V. 2010. Systems biology approaches and tools for analysis of interactomes and multitarget drugs. Meth Mol Biol 662: 29-58.
-
(2010)
Meth Mol Biol
, vol.662
, pp. 29-58
-
-
Schrattenholz, A.1
Groebe, K.2
Soskic, V.3
-
65
-
-
0037069467
-
Analysis of optimality in natural and perturbed metabolic networks
-
Segrè D, Vitkup D, Church GM. 2002. Analysis of optimality in natural and perturbed metabolic networks. Proc Natl Acad Sci 99: 15112-15117.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 15112-15117
-
-
Segrè, D.1
Vitkup, D.2
Church, G.M.3
-
66
-
-
51349092391
-
Network-based prediction of human tissue-specific metabolism
-
Shlomi T, Cabili MN, Herrga°rd MJ, Palsson BO, Ruppin E. 2008. Network-based prediction of human tissue-specific metabolism. Nat Biotechnol 26: 1003-1010.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1003-1010
-
-
Shlomi, T.1
Cabili, M.N.2
Herrga°rd, M.J.3
Palsson, B.O.4
Ruppin, E.5
-
67
-
-
84867435330
-
Regulating gene expression through engineered RNA technologies
-
CRC Press, San Diego.
-
Smolke CD, Win MN. 2010. Regulating gene expression through engineered RNA technologies. In The metabolic pathway engineering hand book. CRC Press, San Diego.
-
(2010)
The metabolic pathway engineering hand book
-
-
Smolke, C.D.1
Win, M.N.2
-
68
-
-
33947276100
-
Metabolic modeling of a mutualistic microbial community
-
Stolyar S, Van Dien S, Hillesland KL, Pinel N, Lie TJ, Leigh JA, Stahl DA. 2007. Metabolic modeling of a mutualistic microbial community. Mol Syst Biol 3: 92.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 92
-
-
Stolyar, S.1
Van Dien, S.2
Hillesland, K.L.3
Pinel, N.4
Lie, T.J.5
Leigh, J.A.6
Stahl, D.A.7
-
69
-
-
1842324170
-
A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression
-
Strähle U, Klock G, Schütz G. 1987. A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc Natl Acad Sci 84: 7871-7875.
-
(1987)
Proc Natl Acad Sci
, vol.84
, pp. 7871-7875
-
-
Strähle, U.1
Klock, G.2
Schütz, G.3
-
70
-
-
80052398214
-
Human metabolic individuality in biomedical and pharmaceutical research
-
CARDIoGRAM
-
Suhre K, Shin S-Y, Petersen A-K, Mohney RP, Meredith D, Wägele B, Altmaier E, CARDIoGRAM, Deloukas P, Erdmann J, et al. 2011. Human metabolic individuality in biomedical and pharmaceutical research. Nature 477: 54-60.
-
(2011)
Nature
, vol.477
, pp. 54-60
-
-
Suhre, K.1
Shin, S.-Y.2
Petersen, A.-K.3
Mohney, R.P.4
Meredith, D.5
Wägele, B.6
Altmaier, E.7
Deloukas, P.8
Erdmann, J.9
-
71
-
-
0037628628
-
Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulinproducing cells
-
Suzuki A, Nakauchi H, Taniguchi H. 2003. Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulinproducing cells. Proc Natl Acad Sci 100: 5034-5039.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 5034-5039
-
-
Suzuki, A.1
Nakauchi, H.2
Taniguchi, H.3
-
72
-
-
51149102891
-
Intron length increases oscillatory periods of gene expression in animal cells
-
Swinburne IA, Miguez DG, Landgraf D, Silver PA. 2008. Intron length increases oscillatory periods of gene expression in animal cells. Genes Dev 22: 2342-2346.
-
(2008)
Genes Dev
, vol.22
, pp. 2342-2346
-
-
Swinburne, I.A.1
Miguez, D.G.2
Landgraf, D.3
Silver, P.A.4
-
73
-
-
23744451791
-
A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia
-
Tang YL, Tang Y, Zhang YC, Agarwal A, Kasahara H, Qian K, Shen L, Phillips MI. 2005. A hypoxia-inducible vigilant vector system for activating therapeutic genes in ischemia. Gene Ther 12: 1163-1170.
-
(2005)
Gene Ther
, vol.12
, pp. 1163-1170
-
-
Tang, Y.L.1
Tang, Y.2
Zhang, Y.C.3
Agarwal, A.4
Kasahara, H.5
Qian, K.6
Shen, L.7
Phillips, M.I.8
-
75
-
-
0030574067
-
Design of metabolic control for large flux changes
-
Thomas S, Fell DA. 1996. Design of metabolic control for large flux changes. J Theor Biol 182: 285-298.
-
(1996)
J Theor Biol
, vol.182
, pp. 285-298
-
-
Thomas, S.1
Fell, D.A.2
-
77
-
-
79957902145
-
Gut microbiome, obesity, and metabolic dysfunction
-
Tilg H, Kaser A. 2011. Gut microbiome, obesity, and metabolic dysfunction. J Clin Invest 121: 2126-2132.
-
(2011)
J Clin Invest
, vol.121
, pp. 2126-2132
-
-
Tilg, H.1
Kaser, A.2
|