Neural differentiation of mouse embryonic stem cells as a tool to assess developmental neurotoxicity in vitro

NeuroToxicology

Volumn 33, Issue 5, 2012, Pages 1135-1146

  Visan, Anke ^a   Hayess, Katrin ^a   Sittner, Dana ^a   Pohl, Elena E ^b,c   Riebeling, Christian ^a   Slawik, Birgitta ^a   Gulich, Konrad ^a   Oelgeschläger, Michael ^a   Luch, Andreas ^a   Seiler, Andrea E M ^a  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

Developmental neurotoxicity; Embryonic stem cells; In vitro developmental neurotoxicity testing

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM ION; CHLORPYRIFOS; DOPAMINE RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE SODIUM; LEAD ACETATE; METHYLMERCURIC CHLORIDE; MICROTUBULE ASSOCIATED PROTEIN 2; POSTSYNAPTIC DENSITY PROTEIN 95; SEROTONIN; SYNAPTOPHYSIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL STRUCTURE; CELL TYPE; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; EMBRYO; EMBRYONIC STEM CELL; FLOW CYTOMETRY; GLIA CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE MICROSCOPY; IN VITRO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPRODUCIBILITY; TOXICITY TESTING;

2',3'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; ASTROCYTES; CALCIUM; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHLORPYRIFOS; DOPAMINE; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; GUANYLATE KINASE; MEMBRANE PROTEINS; METHYLMERCURY COMPOUNDS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; N-METHYLASPARTATE; NEURONS; OLIGODENDROGLIA; ORGANOMETALLIC COMPOUNDS; SODIUM GLUTAMATE; TIME FACTORS; TUBULIN; TYROSINE 3-MONOOXYGENASE;

EID: 84867231149     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.06.006     Document Type: Article

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