Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum

Journal of Neurochemistry

Volumn 119, Issue 2, 2011, Pages 303-313

  Torres Altoro, Melissa I ^a   Mathur, Brian N ^b   Drerup, Justin M ^a   Thomas, Rachel ^a   Lovinger, David M ^b   O'Callaghan, James P ^c   Bibb, James A ^a,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

chlorpyrifos; dopamine; Gulf War illness; insecticide; neurotoxicity; organophosphate

Indexed keywords

AMPA RECEPTOR; CHLORPYRIFOS; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE 5; DIETHYLTOLUAMIDE; DOPAMINE; DYFLOS; GLUTAMATE RECEPTOR 1; ORGANOPHOSPHATE PESTICIDE; PHOSPHOPROTEIN DARPP 32; PYRIDOSTIGMINE; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; FEMALE; MOUSE; NERVE CELL NECROSIS; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; RAT; TOXICITY TESTING;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CHLORPYRIFOS; CHOLINESTERASE INHIBITORS; CORPUS STRIATUM; CYCLIN-DEPENDENT KINASE 5; DOPAMINE; FEMALE; GLUTAMIC ACID; MALE; MICE; MICE, INBRED C57BL; NEURONS; NEUROTOXICITY SYNDROMES; PATCH-CLAMP TECHNIQUES; PHOSPHORIC ACID ESTERS; PHOSPHORYLATION; PYRIDOSTIGMINE BROMIDE; RECEPTORS, DOPAMINE D1; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION; TAU PROTEINS;

ANIMALIA; RATTUS;

EID: 80053572218     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07428.x     Document Type: Article

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