Rat brain CYP2B-enzymatic activation of chlorpyrifos to the oxon mediates cholinergic neurotoxicity

Toxicological Sciences

Volumn 126, Issue 2, 2012, Pages 325-335

  Khokhar, Jibran Y ^a   Tyndale, Rachel F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Brain; Chlorpyrifos; CYP2B; Inhibition; Neurotoxicity; Oxon

Indexed keywords

ACETYLCHOLINESTERASE; CHLORPYRIFOS;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; BEHAVIOR; BODY TEMPERATURE; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVATION; GAIT; IN VITRO STUDY; MALE; METABOLISM; NEUROTOXICITY; NONHUMAN; PHYSIOLOGY; RAT; RIGHTING REFLEX;

RATTUS;

EID: 84859090862     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs029     Document Type: Article

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