메뉴 건너뛰기




Volumn 16, Issue 11, 2012, Pages 1424-1432

The knowns and unknowns of the immunopathogenesis of tuberculosis

Author keywords

Immunopathogenic mechanisms; Immunopathology; Mycobacterium tuberculosis

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; REGION OF DIFFERENCE 1 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84867198092     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: 10.5588/ijtld.12.0479     Document Type: Review
Times cited : (42)

References (91)
  • 2
    • 84863690353 scopus 로고    scopus 로고
    • Vaccines against tuberculosis: Where are we and where do we need to go?
    • Ottenhoff T H, Kaufmann S H. Vaccines against tuberculosis: where are we and where do we need to go? PLoS Pathog 2012; 8: e1002607.
    • (2012) PLoS Pathog , vol.8
    • Ottenhoff, T.H.1    Kaufmann, S.H.2
  • 5
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
    • Keane J, Gershon S, Wise R P, et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 2001; 345: 1098-1104.
    • (2001) N Engl J Med , vol.345 , pp. 1098-1104
    • Keane, J.1    Gershon, S.2    Wise, R.P.3
  • 6
    • 73349135673 scopus 로고    scopus 로고
    • Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
    • Cobat A, Gallant C J, Simkin L, et al. Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis. J Exp Med 2009; 206: 2583-2591.
    • (2009) J Exp Med , vol.206 , pp. 2583-2591
    • Cobat, A.1    Gallant, C.J.2    Simkin, L.3
  • 8
    • 79955101596 scopus 로고    scopus 로고
    • Initiation and regulation of T-cell responses in tuberculosis
    • Urdahl K B, Shafiani S, Ernst J D. Initiation and regulation of T-cell responses in tuberculosis. Mucosal Immunol 2011; 4: 288-293.
    • (2011) Mucosal Immunol , vol.4 , pp. 288-293
    • Urdahl, K.B.1    Shafiani, S.2    Ernst, J.D.3
  • 9
    • 38749138163 scopus 로고    scopus 로고
    • Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
    • DOI 10.1084/jem.20071367
    • Wolf A J, Desvignes L, Linas B, et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med 2008; 205: 105-115. (Pubitemid 351185719)
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.1 , pp. 105-115
    • Wolf, A.J.1    Desvignes, L.2    Linas, B.3    Banaiee, N.4    Tamura, T.5    Takatsu, K.6    Ernst, J.D.7
  • 10
    • 49449098413 scopus 로고    scopus 로고
    • ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
    • Reiley W W, Calayag M D, Wittmer S T, et al. ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes. Proc Natl Acad Sci USA 2008; 105: 10961-10966.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 10961-10966
    • Reiley, W.W.1    Calayag, M.D.2    Wittmer, S.T.3
  • 11
    • 53349118087 scopus 로고    scopus 로고
    • Delayed protection by ESAT-6-specific effector CD4+ T-cells after airborne M. tuberculosis infection
    • Gallegos A M, Pamer E G, Glickman M S. Delayed protection by ESAT-6-specific effector CD4+ T-cells after airborne M. tuberculosis infection. J Exp Med 2008; 205: 2359-2368.
    • (2008) J Exp Med , vol.205 , pp. 2359-2368
    • Gallegos, A.M.1    Pamer, E.G.2    Glickman, M.S.3
  • 12
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
    • Gutierrez M G, Master S S, Singh S B, Taylor G A, Colombo M I, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004; 119: 753-766. (Pubitemid 40017683)
    • (2004) Cell , vol.119 , Issue.6 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 13
    • 33745357459 scopus 로고    scopus 로고
    • Autophagy as an immune defense mechanism
    • DOI 10.1016/j.coi.2006.05.019, PII S095279150600094X
    • Deretic V. Autophagy as an immune defense mechanism. Curr Opin Immunol 2006; 18: 375-382. (Pubitemid 43947574)
    • (2006) Current Opinion in Immunology , vol.18 , Issue.4 , pp. 375-382
    • Deretic, V.1
  • 14
    • 34548591486 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the environment within the phagosome
    • DOI 10.1111/j.1600-065X.2007.00547.x
    • Rohde K, Yates R M, Purdy G E, Russell D G. Mycobacterium tuberculosis and the environment within the phagosome. I mmunol Rev 2007; 219: 37-54. (Pubitemid 47390002)
    • (2007) Immunological Reviews , vol.219 , Issue.1 , pp. 37-54
    • Rohde, K.1    Yates, R.M.2    Purdy, G.E.3    Russell, D.G.4
  • 16
    • 34250716965 scopus 로고    scopus 로고
    • M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
    • DOI 10.1016/j.cell.2007.05.059, PII S0092867407007829
    • van der Wel N, Hava D, Houben D, et al. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 2007; 129: 1287-1298. (Pubitemid 46962098)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1287-1298
    • Van Der Wel, N.1    Hava, D.2    Houben, D.3    Fluitsma, D.4    Van Zon, M.5    Pierson, J.6    Brenner, M.7    Peters, P.J.8
  • 17
    • 84865792720 scopus 로고    scopus 로고
    • New pathways of protective and pathological host defense to mycobacteria discovered in tuberculosis and leprosy
    • Ottenhoff T H. New pathways of protective and pathological host defense to mycobacteria discovered in tuberculosis and leprosy. Trends Microbiol 2012; 20: 419-428.
    • (2012) Trends Microbiol , vol.20 , pp. 419-428
    • Ottenhoff, T.H.1
  • 18
    • 84860247190 scopus 로고    scopus 로고
    • Revisiting the role of the granuloma in tuberculosis
    • Ramakrishnan L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol 2012; 12: 352-366.
    • (2012) Nat Rev Immunol , vol.12 , pp. 352-366
    • Ramakrishnan, L.1
  • 19
    • 79951899229 scopus 로고    scopus 로고
    • For better or for worse: The immune response against Mycobacterium tuberculosis balances pathology and protection
    • Dorhoi A, Reece S T, Kaufmann S H. For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection. Immunol Rev 2011; 240: 235-251.
    • (2011) Immunol Rev , vol.240 , pp. 235-251
    • Dorhoi, A.1    Reece, S.T.2    Kaufmann, S.H.3
  • 20
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: The human model
    • DOI 10.1146/annurev.immunol.20.081501.125851
    • Casanova J L, Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002; 20: 581-620. (Pubitemid 34293435)
    • (2002) Annual Review of Immunology , vol.20 , pp. 581-620
    • Casanova, J.-L.1    Abel, L.2
  • 21
    • 0023000278 scopus 로고
    • Molecular localization and polymorphism of HLA class II restriction determinants defined by Mycobacterium leprae-reactive helper T cell clones from leprosy patients
    • Ottenhoff T H, Neuteboom S, Elferink D G, de Vries R R. Molecular localization and polymorphism of HLA class II restriction determinants defined by Mycobacterium leprae-reactive helper T cell clones from leprosy patients. J Exp Med 1986; 164: 1923-1939. (Pubitemid 17217974)
    • (1986) Journal of Experimental Medicine , vol.164 , Issue.6 , pp. 1923-1939
    • Ottenhoff, T.H.M.1    Neuteboom, S.2    Elferink, D.G.3    De Vries, R.R.P.4
  • 22
    • 0026516797 scopus 로고
    • Binding of a major T-cell epitope of mycobacteria to a specific pocket within HLA-DRw17(DR3) molecules
    • Geluk A, Bloemhoff W, de Vries R R, Ottenhoff T H. Binding of a major T-cell epitope of mycobacteria to a specific pocket within HLA-DRw17(DR3) molecules. Eur J Immunol 1992; 22: 107-113.
    • (1992) Eur J Immunol , vol.22 , pp. 107-113
    • Geluk, A.1    Bloemhoff, W.2    De Vries, R.R.3    Ottenhoff, T.H.4
  • 23
    • 0028987317 scopus 로고
    • Immune response to Mycobacterium bovis bacille Calmette Guérin infection in major histocompatibility complex class I- And II-deficient knockout mice: Contribution of CD4 and CD8 T cells to acquired resistance
    • Ladel C H, Daugelat S, Kaufmann S H. Immune response to Mycobacterium bovis bacille Calmette Guérin infection in major histocompatibility complex class I- and II-deficient knockout mice: contribution of CD4 and CD8 T cells to acquired resistance. Eur J Immunol 1995; 25: 377-384.
    • (1995) Eur J Immunol , vol.25 , pp. 377-384
    • Ladel, C.H.1    Daugelat, S.2    Kaufmann, S.H.3
  • 24
    • 79956302280 scopus 로고    scopus 로고
    • Intravital imaging reveals limited antigen presentation and T-cell effector function in mycobacterial granulomas
    • Egen J G, Rothfuchs A G, Feng C G, Horwitz M A, Sher A, Germain R N. Intravital imaging reveals limited antigen presentation and T-cell effector function in mycobacterial granulomas. Immunity 2011; 34: 807-819.
    • (2011) Immunity , vol.34 , pp. 807-819
    • Egen, J.G.1    Rothfuchs, A.G.2    Feng, C.G.3    Horwitz, M.A.4    Sher, A.5    Germain, R.N.6
  • 26
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper A M. Cell-mediated immune responses in tuberculosis. Annu Rev Immunol 2009; 27: 393-422.
    • (2009) Annu Rev Immunol , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 27
    • 77952774172 scopus 로고    scopus 로고
    • Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung
    • Okamoto Y Y, Umemura M, Yahagi A, et al. Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung. J Immunol 2010; 184: 4414-4422.
    • (2010) J Immunol , vol.184 , pp. 4414-4422
    • Okamoto, Y.Y.1    Umemura, M.2    Yahagi, A.3
  • 28
    • 77955390095 scopus 로고    scopus 로고
    • Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis
    • Cruz A, Fraga A G, Fountain J J, et al. Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J Exp Med 2010; 207: 1609-1616.
    • (2010) J Exp Med , vol.207 , pp. 1609-1616
    • Cruz, A.1    Fraga, A.G.2    Fountain, J.J.3
  • 29
    • 79751529842 scopus 로고    scopus 로고
    • Cellular response to mycobacteria: Balancing protection and pathology
    • Torrado E, Robinson R T, Cooper A M. Cellular response to mycobacteria: balancing protection and pathology. Trends Immunol 2011; 32: 66-72.
    • (2011) Trends Immunol , vol.32 , pp. 66-72
    • Torrado, E.1    Robinson, R.T.2    Cooper, A.M.3
  • 30
    • 77958189493 scopus 로고    scopus 로고
    • Human CD4 and CD8 T-cell responses to Mycobacterium tuberculosis: Antigen specificity, function, implications and applications
    • Kaufmann S H E, Britton W J, eds. Weinheim, Germany: Wiley-VCH Verlag
    • Ottenhoff T H, Lewinsohn D A, Lewinsohn D M. Human CD4 and CD8 T-cell responses to Mycobacterium tuberculosis: antigen specificity, function, implications and applications. In: Kaufmann S H E, Britton W J, eds. Handbook of tuberculosis. Weinheim, Germany: Wiley-VCH Verlag, 2008: pp 119-156.
    • (2008) Handbook of Tuberculosis , pp. 119-156
    • Ottenhoff, T.H.1    Lewinsohn, D.A.2    Lewinsohn, D.M.3
  • 33
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin H W. Autophagy in immunity and inflammation. Nature 2011; 469: 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 34
    • 77951256153 scopus 로고    scopus 로고
    • Autophagy in infection
    • Deretic V. Autophagy in infection. Curr Opin Cell Biol 2010; 22: 252-262.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 252-262
    • Deretic, V.1
  • 35
    • 77649260171 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity
    • Joosten S A, van Meijgaarden K E, van Weeren P C, et al. Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity. PLoS Pathog 2010; 6: e1000782.
    • (2010) PLoS Pathog , vol.6
    • Joosten, S.A.1    Van Meijgaarden, K.E.2    Van Weeren, P.C.3
  • 37
    • 77954701928 scopus 로고    scopus 로고
    • Human mucosal associated invariant T-cells detect bacterially infected cells
    • Gold M C, Cerri S, Smyk-Pearson S, et al. Human mucosal associated invariant T-cells detect bacterially infected cells. PLoS Biol 2010; 8: e1000407.
    • (2010) PLoS Biol , vol.8
    • Gold, M.C.1    Cerri, S.2    Smyk-Pearson, S.3
  • 38
    • 66149179356 scopus 로고    scopus 로고
    • Antigen presentation by CD1 lipids, T-cells, and NKT cells in microbial immunity
    • Cohen N R, Garg S, Brenner M B. Antigen presentation by CD1 lipids, T-cells, and NKT cells in microbial immunity. Adv Immunol 2009; 102: 1-94.
    • (2009) Adv Immunol , vol.102 , pp. 1-94
    • Cohen, N.R.1    Garg, S.2    Brenner, M.B.3
  • 39
    • 66349110544 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle
    • Grotzke J E, Harriff M J, Siler A C, et al. The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. PLoS Pathog 2009; 5: e1000374.
    • (2009) PLoS Pathog , vol.5
    • Grotzke, J.E.1    Harriff, M.J.2    Siler, A.C.3
  • 40
    • 0034502343 scopus 로고    scopus 로고
    • Persistence of DNA from Mycobacterium tuberculosis in superfi cially normal lung tissue during latent infection
    • Hernandez-Pando R, Jeyanathan M, Mengistu G, et al. Persistence of DNA from Mycobacterium tuberculosis in superfi cially normal lung tissue during latent infection. Lancet 2000; 356: 2133-2138.
    • (2000) Lancet , vol.356 , pp. 2133-2138
    • Hernandez-Pando, R.1    Jeyanathan, M.2    Mengistu, G.3
  • 42
    • 33746214785 scopus 로고    scopus 로고
    • Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens
    • Caccamo N, Meraviglia S, La M C, Guggino G, Dieli F, Salerno A. Phenotypical and functional analysis of memory and effector human CD8 T-cells specific for mycobacterial antigens. J Immunol 2006; 177: 1780-1785. (Pubitemid 44092515)
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1780-1785
    • Caccamo, N.1    Meraviglia, S.2    La, M.C.3    Guggino, G.4    Dieli, F.5    Salerno, A.6
  • 44
    • 79954486176 scopus 로고    scopus 로고
    • Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals
    • Commandeur S, van Meijgaarden K E, Lin M Y, et al. Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals. Clin Vaccine Immunol 2011; 18: 676-683.
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 676-683
    • Commandeur, S.1    Van Meijgaarden, K.E.2    Lin, M.Y.3
  • 45
    • 0033842323 scopus 로고    scopus 로고
    • Role of CD8(+) T cells in mycobacterial infections
    • DOI 10.1046/j.1440-1711.2000.00936.x
    • Smith S M, Dockrell H M. Role of CD8 T-cells in mycobacterial infections. Immunol Cell Biol 2000; 78: 325-333. (Pubitemid 30655558)
    • (2000) Immunology and Cell Biology , vol.78 , Issue.4 , pp. 325-333
    • Smith, S.M.1    Dockrell, H.M.2
  • 47
    • 65849488547 scopus 로고    scopus 로고
    • Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection
    • Caccamo N, Guggino G, Meraviglia S, et al. Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection. PLoS ONE 2009; 4: e5528.
    • (2009) PLoS ONE , vol.4
    • Caccamo, N.1    Guggino, G.2    Meraviglia, S.3
  • 48
    • 64049113596 scopus 로고    scopus 로고
    • How B cells shape the immune response against Mycobacterium tuberculosis
    • Maglione P J, Chan J. How B cells shape the immune response against Mycobacterium tuberculosis. Eur J Immunol 2009; 39: 676-686.
    • (2009) Eur J Immunol , vol.39 , pp. 676-686
    • Maglione, P.J.1    Chan, J.2
  • 49
    • 77955894773 scopus 로고    scopus 로고
    • An interferoni nducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry M P, Graham C M, McNab F W, et al. An interferoni nducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010; 466: 973-977.
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3
  • 50
    • 78751648792 scopus 로고    scopus 로고
    • Human gene expression profiles of susceptibility and resistance in tuberculosis
    • Maertzdorf J, Repsilber D, Parida S K, et al. Human gene expression profiles of susceptibility and resistance in tuberculosis. Genes Immun 2011; 12: 15-22.
    • (2011) Genes Immun , vol.12 , pp. 15-22
    • Maertzdorf, J.1    Repsilber, D.2    Parida, S.K.3
  • 51
    • 84861035952 scopus 로고    scopus 로고
    • Common patterns and disease-related signatures in tuberculosis and sarcoidosis
    • Maertzdorf J, Weiner J III, Mollenkopf H J, et al. Common patterns and disease-related signatures in tuberculosis and sarcoidosis. Proc Natl Acad Sci USA 2012; 109: 7853-7858.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 7853-7858
    • Maertzdorf, J.1    Weiner III, J.2    Mollenkopf, H.J.3
  • 52
    • 77954390239 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T-cells delay the arrival of effector T-cells in the lung during early tuberculosis
    • Shafiani S, Tucker-Heard G, Kariyone A, Takatsu K, Urdahl K B. Pathogen-specific regulatory T-cells delay the arrival of effector T-cells in the lung during early tuberculosis. J Exp Med 2010; 207: 1409-1420.
    • (2010) J Exp Med , vol.207 , pp. 1409-1420
    • Shafiani, S.1    Tucker-Heard, G.2    Kariyone, A.3    Takatsu, K.4    Urdahl, K.B.5
  • 55
    • 57649090701 scopus 로고    scopus 로고
    • Human CD4 and CD8 regulatory T-cells in infectious diseases and vaccination
    • Joosten S A, Ottenhoff T H. Human CD4 and CD8 regulatory T-cells in infectious diseases and vaccination. Hum Immunol 2008; 69: 760-770.
    • (2008) Hum Immunol , vol.69 , pp. 760-770
    • Joosten, S.A.1    Ottenhoff, T.H.2
  • 57
    • 22944433876 scopus 로고    scopus 로고
    • The success and failure of BCG - Implications for a novel tuberculosis vaccine
    • DOI 10.1038/nrmicro1211
    • Andersen P, Doherty T M. The success and failure of BCG- implications for a novel tuberculosis vaccine. Nat Rev Microbiol 2005; 3: 656-662. (Pubitemid 41052152)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.8 , pp. 656-662
    • Andersen, P.1    Doherty, T.M.2
  • 59
    • 77958475885 scopus 로고    scopus 로고
    • Specific T-cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns
    • Kagina B M, Abel B, Scriba T J, et al. Specific T-cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns. Am J Respir Crit Care Med 2010; 182: 1073-1079.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1073-1079
    • Kagina, B.M.1    Abel, B.2    Scriba, T.J.3
  • 60
    • 64049095274 scopus 로고    scopus 로고
    • Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease
    • Sutherland J S, Adetifa I M, Hill P C, Adegbola R A, Ota M O. Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol 2009; 39: 723-729.
    • (2009) Eur J Immunol , vol.39 , pp. 723-729
    • Sutherland, J.S.1    Adetifa, I.M.2    Hill, P.C.3    Adegbola, R.A.4    Ota, M.O.5
  • 61
    • 77956108181 scopus 로고    scopus 로고
    • Multifunctional CD4(+) T-cells correlate with active Mycobacterium tuberculosis infection
    • Caccamo N, Guggino G, Joosten S A, et al. Multifunctional CD4(+) T-cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 2010; 40: 2211-2220.
    • (2010) Eur J Immunol , vol.40 , pp. 2211-2220
    • Caccamo, N.1    Guggino, G.2    Joosten, S.A.3
  • 62
    • 77954288837 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
    • Smith S G, Lalor M K, Gorak-Stolinska P, et al. Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining. BMC Immunol 2010; 11: 35.
    • (2010) BMC Immunol , vol.11 , pp. 35
    • Smith, S.G.1    Lalor, M.K.2    Gorak-Stolinska, P.3
  • 64
    • 80052086428 scopus 로고    scopus 로고
    • Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway
    • Potian J A, RafiW, Bhatt K, McBride A, Gause W C, Salgame P. Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway. J Exp Med 2011; 208: 1863-1874.
    • (2011) J Exp Med , vol.208 , pp. 1863-1874
    • Potian, J.A.1    Rafi, W.2    Bhatt, K.3    McBride, A.4    Gause, W.C.5    Salgame, P.6
  • 65
    • 68149098007 scopus 로고    scopus 로고
    • Overcoming the global crisis: 'yes, we can', but also for TB...?
    • Ottenhoff T H. Overcoming the global crisis: 'yes, we can', but also for TB . . . ? Eur J Immunol 2009; 39: 2014-2020.
    • (2009) Eur J Immunol , vol.39 , pp. 2014-2020
    • Ottenhoff, T.H.1
  • 66
    • 45749106329 scopus 로고    scopus 로고
    • Not to wake a sleeping giant: New insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection
    • DOI 10.1515/BC.2008.057
    • Lin M Y, Ottenhoff T H. Not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection. Biol Chem 2008; 389: 497-511. (Pubitemid 351874191)
    • (2008) Biological Chemistry , vol.389 , Issue.5 , pp. 497-511
    • Lin, M.Y.1    Ottenhoff, T.H.M.2
  • 69
    • 40749159713 scopus 로고    scopus 로고
    • Distinct, specific IL-17- And IL-22-producing CD4+ T-cell subsets contribute to the human anti-mycobacterial immune response
    • Scriba T J, Kalsdorf B, Abrahams D A, et al. Distinct, specific IL-17- and IL-22-producing CD4+ T-cell subsets contribute to the human anti-mycobacterial immune response. J Immunol 2008; 180: 1962-1970.
    • (2008) J Immunol , vol.180 , pp. 1962-1970
    • Scriba, T.J.1    Kalsdorf, B.2    Abrahams, D.A.3
  • 70
    • 75249086006 scopus 로고    scopus 로고
    • Complex cytokine profi les induced by BCG vaccination in UK infants
    • Lalor M K, Smith S G, Floyd S, et al. Complex cytokine profi les induced by BCG vaccination in UK infants. Vaccine 2010; 28: 1635-1641.
    • (2010) Vaccine , vol.28 , pp. 1635-1641
    • Lalor, M.K.1    Smith, S.G.2    Floyd, S.3
  • 71
    • 84867210478 scopus 로고    scopus 로고
    • Human genetic susceptibility to Candida infections
    • Jun 4. [Epub ahead of print]
    • Plantinga T S, Johnson M D, Scott W K, et al. Human genetic susceptibility to Candida infections. Med Mycol 2012; Jun 4. [Epub ahead of print]
    • (2012) Med Mycol
    • Plantinga, T.S.1    Johnson, M.D.2    Scott, W.K.3
  • 73
    • 84856003520 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T-cells
    • Blomgran R, Desvignes L, Briken V, Ernst J D. Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T-cells. Cell Host Microbe 2012; 11: 81-90.
    • (2012) Cell Host Microbe , vol.11 , pp. 81-90
    • Blomgran, R.1    Desvignes, L.2    Briken, V.3    Ernst, J.D.4
  • 74
    • 77954623962 scopus 로고    scopus 로고
    • Airway luminal T-cells: A newcomer on the stage of TB vaccination strategies
    • Jeyanathan M, Heriazon A, Xing Z. Airway luminal T-cells: a newcomer on the stage of TB vaccination strategies. Trends Immunol 2010; 31: 247-252.
    • (2010) Trends Immunol , vol.31 , pp. 247-252
    • Jeyanathan, M.1    Heriazon, A.2    Xing, Z.3
  • 75
    • 77953070464 scopus 로고    scopus 로고
    • Murine airway luminal anti-tuberculosis memory CD8 T-cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment
    • Jeyanathan M, Mu J, McCormick S, et al. Murine airway luminal anti-tuberculosis memory CD8 T-cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment. Am J Respir Crit Care Med 2010; 181: 862-872.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 862-872
    • Jeyanathan, M.1    Mu, J.2    McCormick, S.3
  • 76
    • 77949532239 scopus 로고    scopus 로고
    • Immunization of mice with a recombinant adenovirus vaccine inhibits the early growth of Mycobacterium tuberculosis after infection
    • Ronan E O, Lee L N, Beverley P C, Tchilian E Z. Immunization of mice with a recombinant adenovirus vaccine inhibits the early growth of Mycobacterium tuberculosis after infection. PLoS ONE 2009; 4: e8235.
    • (2009) PLoS ONE , vol.4
    • Ronan, E.O.1    Lee, L.N.2    Beverley, P.C.3    Tchilian, E.Z.4
  • 77
    • 81155131557 scopus 로고    scopus 로고
    • Simultaneous immunization against tuberculosis
    • Tchilian E Z, Ronan E O, de Lara C, et al. Simultaneous immunization against tuberculosis. PLoS ONE 2011; 6: e27477.
    • (2011) PLoS ONE , vol.6
    • Tchilian, E.Z.1    Ronan, E.O.2    De Lara, C.3
  • 78
    • 79961117289 scopus 로고    scopus 로고
    • CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis
    • Lee L N, Ronan E O, de Lara C, et al. CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis. Infect Immun 2011; 79: 3328-3337.
    • (2011) Infect Immun , vol.79 , pp. 3328-3337
    • Lee, L.N.1    Ronan, E.O.2    De Lara, C.3
  • 79
    • 0034651738 scopus 로고    scopus 로고
    • Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages
    • Keane J, Remold H G, Kornfeld H. Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages. J Immunol 2000; 164: 2016-2020. (Pubitemid 30108758)
    • (2000) Journal of Immunology , vol.164 , Issue.4 , pp. 2016-2020
    • Keane, J.1    Remold, H.G.2    Kornfeld, H.3
  • 81
    • 84856693171 scopus 로고    scopus 로고
    • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
    • Tobin D M, Roca F J, Oh S F, et al. Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 2012; 148: 434-446.
    • (2012) Cell , vol.148 , pp. 434-446
    • Tobin, D.M.1    Roca, F.J.2    Oh, S.F.3
  • 83
    • 0031750080 scopus 로고    scopus 로고
    • A combination of thalidomide plus antibiotics protects rabbits from mycobacterial meningitis-Associated death
    • Tsenova L, Sokol K, Freedman V H, Kaplan G. A combination of thalidomide plus antibiotics protects rabbits from mycobacterial meningitis-associated death. J Infect Dis 1998; 177: 1563-1572. (Pubitemid 28243580)
    • (1998) Journal of Infectious Diseases , vol.177 , Issue.6 , pp. 1563-1572
    • Tsenova, L.1    Sokol, K.2    Freedman, V.H.3    Kaplan, G.4
  • 84
    • 77649128120 scopus 로고    scopus 로고
    • The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
    • Tobin D M, Vary J C Jr, Ray J P, et al. The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 2010; 140: 717-730.
    • (2010) Cell , vol.140 , pp. 717-730
    • Tobin, D.M.1    Vary Jr., J.C.2    Ray, J.P.3
  • 85
    • 84861039988 scopus 로고    scopus 로고
    • Pathogenesis of the immune reconstitution inflammatory syndrome in HIVi nfected patients
    • Martin-Blondel G, Mars L T, Liblau R S. Pathogenesis of the immune reconstitution inflammatory syndrome in HIVi nfected patients. Curr Opin Infect Dis 2012; 25: 312-320.
    • (2012) Curr Opin Infect Dis , vol.25 , pp. 312-320
    • Martin-Blondel, G.1    Mars, L.T.2    Liblau, R.S.3
  • 87
    • 70349439285 scopus 로고    scopus 로고
    • Dissection of regenerating T-cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis
    • Wilkinson K A, Seldon R, Meintjes G, et al. Dissection of regenerating T-cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis. Am J Respir Crit Care Med 2009; 180: 674-683.
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 674-683
    • Wilkinson, K.A.1    Seldon, R.2    Meintjes, G.3
  • 88
    • 84859186806 scopus 로고    scopus 로고
    • Selective expansion of polyfunctional pathogen-specific CD4(+) T-cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome
    • Mahnke Y D, Greenwald J H, DerSimonian R, et al. Selective expansion of polyfunctional pathogen-specific CD4(+) T-cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome. Blood 2012; 119: 3105-3112.
    • (2012) Blood , vol.119 , pp. 3105-3112
    • Mahnke, Y.D.1    Greenwald, J.H.2    DerSimonian, R.3
  • 89
    • 57349186692 scopus 로고    scopus 로고
    • Type 1-helper T-cells and FoxP3-positive T-cells in HIV-tuberculosis- associated immune reconstitution inflammatory syndrome
    • Meintjes G, Wilkinson K A, Rangaka M X, et al. Type 1-helper T-cells and FoxP3-positive T-cells in HIV-tuberculosis-associated immune reconstitution inflammatory syndrome. Am J Respir Crit Care Med 2008; 178: 1083-1089.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 1083-1089
    • Meintjes, G.1    Wilkinson, K.A.2    Rangaka, M.X.3
  • 90
    • 79955657919 scopus 로고    scopus 로고
    • Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome
    • Tadokera R, Meintjes G, Skolimowska K H, et al. Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome. Eur Respir J 2011; 37: 1248-1259.
    • (2011) Eur Respir J , vol.37 , pp. 1248-1259
    • Tadokera, R.1    Meintjes, G.2    Skolimowska, K.H.3
  • 91
    • 19344378561 scopus 로고    scopus 로고
    • Dendritic cell numbers in the blood of HIV-1 infected patients before and after changes in antiretroviral therapy
    • DOI 10.1007/s10875-004-6250-5
    • Finke J S, Shodell M, Shah K, Siegal F P, Steinman R M. Dendritic cell numbers in the blood of HIV-1 infected patients before and after changes in antiretroviral therapy. J Clin Immunol 2004; 24: 647-652. (Pubitemid 40933116)
    • (2004) Journal of Clinical Immunology , vol.24 , Issue.6 , pp. 647-652
    • Finke, J.S.1    Shodell, M.2    Shah, K.3    Siegal, F.P.4    Steinman, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.