Not to wake a sleeping giant: New insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection

Biological Chemistry

Volumn 389, Issue 5, 2008, Pages 497-511

  Lin, May Young ^a   Ottenhoff, Tom H M ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Bacille Calmette Gu rin (BCG); Dormancy; dosR regulon; M. bovis persistence; Post exposure vaccines; T cells

Indexed keywords

ALPHA CRYSTALLIN; BACTERIAL DNA; BCG VACCINE; CALCIUM BINDING PROTEIN; CALMODULIN; EARLY ANTIGEN; EARLY ANTIGEN AG85A; EARLY ANTIGEN AG85B; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; GUANOSINE TRIPHOSPHATASE; HLA DR ANTIGEN; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 10; INTERLEUKIN 12; LIVE VACCINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MESSENGER RNA; MYCOBACTERIUM VACCINE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 1; NITRIC OXIDE; PROTEIN KINASE B; SUBUNIT VACCINE; TOLL LIKE RECEPTOR; TUBERCULOSTATIC AGENT; TUMOR NECROSIS FACTOR ALPHA; VITAMIN D RECEPTOR;

ACG GENE; ACR GENE; ADAPTIVE IMMUNITY; ANTIGEN EXPRESSION; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BCG VACCINATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL KILLING; CELLULAR IMMUNITY; CHEMICAL GENETICS; COST EFFECTIVENESS ANALYSIS; CROHN DISEASE; CTPF GENE; CYTOKINE PRODUCTION; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DEVR GENE; DEVS GENE; DOSR GENE; DOSS GENE; DRUG TARGETING; FDXA GENE; GENETIC POLYMORPHISM; GRANULOMA; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HSPX GENE; HUMAN; IMMUNE RESPONSE GENE; IMMUNOREGULATION; INFECTION RESISTANCE; INFECTION SENSITIVITY; INNATE IMMUNITY; LIPID METABOLISM; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MEMORY T LYMPHOCYTE; MESSENGER RNA SYNTHESIS; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM TUBERCULOSIS; NARK2 GENE; NARX GENE; NDRZ GENE; NONHUMAN; OTSB1 GENE; PERSISTENT INFECTION; PFKB GENE; POPULATION GENETICS; POSTPRIMARY TUBERCULOSIS; PRIORITY JOURNAL; RECEPTOR GENE; REGULON; REVIEW; SYMPTOM; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TGS GENE; TUBERCULOSIS; TUBERCULOSIS CONTROL;

ANIMALS; ANTITUBERCULAR AGENTS; GENOME; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, CELLULAR; MYCOBACTERIUM TUBERCULOSIS; REGULON; TUBERCULOSIS; TUBERCULOSIS VACCINES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 45749106329     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2008.057     Document Type: Review

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