메뉴 건너뛰기




Volumn 180, Issue 7, 2009, Pages 674-683

Dissection of regenerating T-cell responses against tuberculosis in HIV-infected adults sensitized by Mycobacterium tuberculosis

Author keywords

Bacterial infections; Drug therapy; RNA viruses

Indexed keywords

CD27 ANTIGEN; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; CYTOKINE; GAMMA INTERFERON; LYMPHOCYTE SURFACE MARKER; TUBERCULIN;

EID: 70349439285     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200904-0568OC     Document Type: Article
Times cited : (54)

References (74)
  • 1
    • 84859744467 scopus 로고    scopus 로고
    • Harrison SBR, Ntuli A, editors. Durban: Health Systems Trust
    • Harrison SBR, Ntuli A, editors. South African health review 2007. Durban: Health Systems Trust; 2007.
    • (2007) South African Health Review 2007
  • 5
    • 33644835815 scopus 로고    scopus 로고
    • Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: Comparison between low-income and high-income countries
    • Braitstein P, Brinkhof MW, Dabis F, Schechter M, Boulle A, Miotti P, Wood R, Laurent C, Sprinz E, Seyler C, et al. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries. Lancet 2006;367:817-824.
    • (2006) Lancet , vol.367 , pp. 817-824
    • Braitstein, P.1    Brinkhof, M.W.2    Dabis, F.3    Schechter, M.4    Boulle, A.5    Miotti, P.6    Wood, R.7    Laurent, C.8    Sprinz, E.9    Seyler, C.10
  • 6
    • 0032490305 scopus 로고    scopus 로고
    • Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease
    • DOI 10.1016/S0140-6736(97)10291-4
    • Li TS, Tubiana R, Katlama C, Calvez V, Ait Mohand H, Autran B. Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease. Lancet 1998;351:1682-1686. (Pubitemid 28254528)
    • (1998) Lancet , vol.351 , Issue.9117 , pp. 1682-1686
    • Li, T.S.1    Tubiana, R.2    Katlama, C.3    Calvez, V.4    Mohand, H.A.5    Autran, B.6
  • 7
    • 0031881026 scopus 로고    scopus 로고
    • Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1
    • Komanduri KV, Viswanathan MN, Wieder ED, Schmidt DK, Bredt BM, Jacobson MA, McCune JM. Restoration of cytomegalovirus-specific CD4+ T-lymphocyte responses after ganciclovir and highly active antiretroviral therapy in individuals infected with HIV-1. Nat Med 1998;4:953-956.
    • (1998) Nat Med , vol.4 , pp. 953-956
    • Komanduri, K.V.1    Viswanathan, M.N.2    Wieder, E.D.3    Schmidt, D.K.4    Bredt, B.M.5    Jacobson, M.A.6    McCune, J.M.7
  • 8
    • 0030868897 scopus 로고    scopus 로고
    • + T cell homeostasis and function in advanced HIV disease
    • DOI 10.1126/science.277.5322.112
    • Autran B, Carcelain G, Li TS, Blanc C, Mathez D, Tubiana R, Katlama C, Debre P, Leibowitch J. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997;277:112-116. (Pubitemid 27450659)
    • (1997) Science , vol.277 , Issue.5322 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Li, T.S.3    Blanc, C.4    Mathez, D.5    Tubiana, R.6    Katlama, C.7    Debre, P.8    Leibowitch, J.9
  • 9
    • 0032732511 scopus 로고    scopus 로고
    • HAART in HIV-infected patients: Restoration of antigen-specific CD4 T-cell responses in vitro is correlated with CD4 memory T-cell reconstitution, whereas improvement in delayed type hypersensitivity is related to a decrease in viraemia
    • DOI 10.1097/00002030-199910010-00007
    • Wendland T, Furrer H, Vernazza PL, Frutig K, Christen A, Matter L, Malinverni R, Pichler WJ. Haart in HIV-infected patients: restoration of antigen-specific CD4 T-cell responses in vitro is correlated with CD4 memory T-cell reconstitution, whereas improvement in delayed type hypersensitivity is related to a decrease in viraemia. AIDS 1999;13:1857-1862. (Pubitemid 29509544)
    • (1999) AIDS , vol.13 , Issue.14 , pp. 1857-1862
    • Wendland, T.1    Furrer, H.2    Vernazza, P.L.3    Frutig, K.4    Christen, A.5    Matter, L.6    Malinverni, R.7    Pichler, W.J.8
  • 10
    • 0036036459 scopus 로고    scopus 로고
    • Reconstitution of immune responses to tuberculosis in patients with HIV infection who receive antiretroviral therapy
    • DOI 10.1378/chest.122.2.597
    • Schluger NW, Perez D, Liu YM. Reconstitution of immune responses to tuberculosis in patients with HIV infection who receive antiretroviral therapy. Chest 2002;122:597-602. (Pubitemid 35002142)
    • (2002) Chest , vol.122 , Issue.2 , pp. 597-602
    • Schluger, N.W.1    Perez, D.2    Liu, Y.M.3
  • 11
    • 33646052566 scopus 로고    scopus 로고
    • Immunological recovery and antiretroviral therapy in HIV-1 infection
    • Battegay M, Nuesch R, Hirschel B, Kaufmann GR. Immunological recovery and antiretroviral therapy in HIV-1 infection. Lancet Infect Dis 2006;6:280-287.
    • (2006) Lancet Infect Dis , vol.6 , pp. 280-287
    • Battegay, M.1    Nuesch, R.2    Hirschel, B.3    Kaufmann, G.R.4
  • 12
    • 0035808787 scopus 로고    scopus 로고
    • The relative importance of T cell subsets in immunity and immunopathology of airborne Mycobacterium tuberculosis infection in mice
    • DOI 10.1084/jem.193.3.271
    • Mogues T, Goodrich ME, Ryan L, LaCourse R, North RJ. The relative importance of T cell subsets in immunity and immunopathology of airborne mycobacterium tuberculosis infection in mice. J Exp Med 2001;193:271-280. (Pubitemid 32524511)
    • (2001) Journal of Experimental Medicine , vol.193 , Issue.3 , pp. 271-280
    • Mogues, T.1    Goodrich, M.E.2    Ryan, L.3    Lacourse, R.4    North, R.J.5
  • 14
    • 0024566140 scopus 로고
    • The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection
    • DOI 10.1016/0092-8674(89)90676-4
    • Kindler V, Sappino AP, Grau GE, Piguet PF, Vassalli P. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 1989;56:731-740. (Pubitemid 19082507)
    • (1989) Cell , vol.56 , Issue.5 , pp. 731-740
    • Kindler, V.1    Sappino, A.-P.2    Grau, G.E.3    Piguet, P.-F.4    Vassalli, P.5
  • 16
    • 0042834294 scopus 로고    scopus 로고
    • Reactivation of latent tuberculosis infection in TNF-deficient mice
    • Botha T, Ryffel B. Reactivation of latent tuberculosis infection in TNF-deficient mice. J Immunol 2003;171:3110-3118. (Pubitemid 37093534)
    • (2003) Journal of Immunology , vol.171 , Issue.6 , pp. 3110-3118
    • Botha, T.1    Ryffel, B.2
  • 22
    • 0034463153 scopus 로고    scopus 로고
    • Correlates of protective immunity to Mycobacterium tuberculosis in humans
    • DOI 10.1086/313874
    • Ellner JJ, Hirsch CS, Whalen CC. Correlates of protective immunity to mycobacterium tuberculosis in humans. Clin Infect Dis 2000;30:S279-S282. (Pubitemid 32250422)
    • (2000) Clinical Infectious Diseases , vol.30 , Issue.SUPPL. 3
    • Ellner, J.J.1    Hirsch, C.S.2    Whalen, C.C.3
  • 23
    • 0037111049 scopus 로고    scopus 로고
    • Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity
    • DOI 10.1086/344359
    • Hoft DF, Worku S, Kampmann B, Whalen CC, Ellner JJ, Hirsch CS, Brown RB, Larkin R, Li Q, Yun H, et al. Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective mycobacterium tuberculosis immunity. J Infect Dis 2002;186:1448-1457. (Pubitemid 35286112)
    • (2002) Journal of Infectious Diseases , vol.186 , Issue.10 , pp. 1448-1457
    • Hoft, D.F.1    Worku, S.2    Kampmann, B.3    Whalen, C.C.4    Ellner, J.J.5    Hirsch, C.S.6    Brown, R.B.7    Larkin, R.8    Li, Q.9    Yun, H.10    Silver, R.F.11
  • 24
    • 36749092454 scopus 로고    scopus 로고
    • Rational design of vaccines against tuberculosis directed by basic immunology
    • Reece ST, Kaufmann SH. Rational design of vaccines against tuberculosis directed by basic immunology. Int J Med Microbiol 2008;298:143-150.
    • (2008) Int J Med Microbiol , vol.298 , pp. 143-150
    • Reece, S.T.1    Kaufmann, S.H.2
  • 25
    • 33646562881 scopus 로고    scopus 로고
    • Tuberculosis vaccines: Current status and future prospects
    • DOI 10.1517/14728214.11.2.207
    • Fletcher H, McShane H. Tuberculosis vaccines: current status and future prospects. Expert Opin Emerg Drugs 2006;11:207-215. (Pubitemid 43723304)
    • (2006) Expert Opinion on Emerging Drugs , vol.11 , Issue.2 , pp. 207-215
    • Fletcher, H.1    McShane, H.2
  • 27
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999;401:708-712. (Pubitemid 129515761)
    • (1999) Nature , vol.401 , Issue.6754 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 30
    • 0041381363 scopus 로고    scopus 로고
    • + effector and memory T cell generation
    • DOI 10.1038/ni969
    • Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol 2003;4:835-842. (Pubitemid 37098653)
    • (2003) Nature Immunology , vol.4 , Issue.9 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 31
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • DOI 10.1146/annurev.immunol.22.012703.104702
    • Sallusto F, Geginat J, Lanzavecchia A. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol 2004;22:745-763. (Pubitemid 38680440)
    • (2004) Annual Review of Immunology , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 32
    • 0034007686 scopus 로고    scopus 로고
    • Risk factors for developing tuberculosis in HIV-1-infected adults from communities with a low or very high incidence of tuberculosis
    • Wood R, Maartens G, Lombard CJ. Risk factors for developing tuberculosis in HIV-1-infected adults from communities with a low or very high incidence of tuberculosis. J Acquir Immune Defic Syndr 2000;23:75-80.
    • (2000) J Acquir Immune Defic Syndr , vol.23 , pp. 75-80
    • Wood, R.1    Maartens, G.2    Lombard, C.J.3
  • 33
    • 17844374605 scopus 로고    scopus 로고
    • + T cells in multiple tissues during acute SIV infection
    • DOI 10.1038/nature03501
    • Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute siv infection. Nature 2005;434:1093-1097. (Pubitemid 40663481)
    • (2005) Nature , vol.434 , Issue.7037 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5    Roederer, M.6
  • 34
    • 0033833932 scopus 로고    scopus 로고
    • Infections with mycobacterium tuberculosis and mycobacterium avium among HIV-infected patients after the introduction of highly active antiretroviral therapy
    • Eurosida study group jd
    • Kirk O, Gatell JM, Mocroft A, Pedersen C, Proenca R, Brettle RP, Barton SE, Sudre P, Phillips AN. Infections with mycobacterium tuberculosis and mycobacterium avium among HIV-infected patients after the introduction of highly active antiretroviral therapy. Eurosida study group jd. Am J Respir Crit Care Med 2000;162:865-872.
    • (2000) Am J Respir Crit Care Med , vol.162 , pp. 865-872
    • Kirk, O.1    Gatell, J.M.2    Mocroft, A.3    Pedersen, C.4    Proenca, R.5    Brettle, R.P.6    Barton, S.E.7    Sudre, P.8    Phillips, A.N.9
  • 35
    • 0033757450 scopus 로고    scopus 로고
    • HIV-associated tuberculosis in the era of highly active antiretroviral therapy
    • The adult/adolescent spectrum of HIV disease group
    • Jones JL, Hanson DL, Dworkin MS, DeCock KM. HIV-associated tuberculosis in the era of highly active antiretroviral therapy. The adult/adolescent spectrum of HIV disease group. Int J Tuberc Lung Dis 2000;4:1026-1031.
    • (2000) Int J Tuberc Lung Dis , vol.4 , pp. 1026-1031
    • Jones, J.L.1    Hanson, D.L.2    Dworkin, M.S.3    DeCock, K.M.4
  • 36
    • 0037097002 scopus 로고    scopus 로고
    • Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: A cohort study
    • DOI 10.1016/S0140-6736(02)08904-3
    • Badri M, Wilson D, Wood R. Effect of highly active antiretroviral therapy on incidence of tuberculosis in South Africa: A cohort study. Lancet 2002;359:2059-2064. (Pubitemid 34680968)
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2059-2064
    • Badri, M.1    Wilson, D.2    Wood, R.3
  • 37
    • 34250822376 scopus 로고    scopus 로고
    • The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil
    • DOI 10.1097/QAD.0b013e328216f441, PII 0000203020070711000007
    • Golub JE, Saraceni V, Cavalcante SC, Pacheco AG, Moulton LH, King BS, Efron A, Moore RD, Chaisson RE, Durovni B. The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil. AIDS 2007;21:1441-1448. (Pubitemid 46988004)
    • (2007) AIDS , vol.21 , Issue.11 , pp. 1441-1448
    • Golub, J.E.1    Saraceni, V.2    Cavalcante, S.C.3    Pacheco, A.G.4    Moulton, L.H.5    King, B.S.6    Efron, A.7    Moore, R.D.8    Chaisson, R.E.9    Durovni, B.10
  • 41
    • 27144461645 scopus 로고    scopus 로고
    • + T cells are predominantly distributed among six phenotypically and functionally distinct subsets
    • Amyes E, McMichael AJ, Callan MF. Human CD4+ T cells are predominantly distributed among six phenotypically and functionally distinct subsets. J Immunol 2005;175:5765-5773. (Pubitemid 41508060)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 5765-5773
    • Amyes, E.1    McMichael, A.J.2    Callan, M.F.C.3
  • 46
    • 0035905477 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1084/jem.194.12.1711
    • Geginat J, Sallusto F, Lanzavecchia A. Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells. J Exp Med 2001;194:1711-1719. (Pubitemid 34028651)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.12 , pp. 1711-1719
    • Geginat, J.1    Sallusto, F.2    Lanzavecchia, A.3
  • 48
    • 0033554677 scopus 로고    scopus 로고
    • Dual personality of memory T cells
    • Mackay CR. Dual personality of memory T cells. Nature 1999;401:659-660.
    • (1999) Nature , vol.401 , pp. 659-660
    • Mackay, C.R.1
  • 52
    • 33745512339 scopus 로고    scopus 로고
    • The immune response to BCG vaccination of newborns
    • Hanekom WA. The immune response to BCG vaccination of newborns. Ann N Y Acad Sci 2005;1062:69-78.
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 69-78
    • Hanekom, W.A.1
  • 53
    • 0032192342 scopus 로고    scopus 로고
    • + T cell population with memory rather than naive cells
    • DOI 10.1016/S0166-3542(98)00035-7, PII S0166354298000357
    • Evans TG, Bonnez W, Soucier HR, Fitzgerald T, Gibbons DC, Reichman RC. Highly active antiretroviral therapy results in a decrease in CD8+ T cell activation and preferential reconstitution of the peripheral CD4+ T cell population with memory rather than naive cells. Antiviral Res 1998;39:163-173. (Pubitemid 28495572)
    • (1998) Antiviral Research , vol.39 , Issue.3 , pp. 163-173
    • Evans, T.G.1    Bonnez, W.2    Soucier, H.R.3    Fitzgerald, T.4    Gibbons, D.C.5    Reichman, R.C.6
  • 54
    • 0034125406 scopus 로고    scopus 로고
    • Decreased CD95 expression on naive T cells from HIV-infected persons undergoing highly active anti-retroviral therapy (HAART) and the influence of IL-2 low dose administration
    • Irhan study group
    • Amendola A, Poccia F, Martini F, Gioia C, Galati V, Pierdominici M, Marziali M, Pandolfi F, Colizzi V, Piacentini M, et al. Decreased CD95 expression on naive T cells from HIV-infected persons undergoing highly active anti-retroviral therapy (HAART) and the influence of IL-2 low dose administration. Irhan study group. Clin Exp Immunol 2000;120:324-332.
    • (2000) Clin Exp Immunol , vol.120 , pp. 324-332
    • Amendola, A.1    Poccia, F.2    Martini, F.3    Gioia, C.4    Galati, V.5    Pierdominici, M.6    Marziali, M.7    Pandolfi, F.8    Colizzi, V.9    Piacentini, M.10
  • 58
    • 0032980441 scopus 로고    scopus 로고
    • Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection
    • DOI 10.1016/S0165-2478(98)00160-6, PII S0165247898001606
    • Pontesilli O, Kerkhof-Garde S, Pakker NG, Notermans DW, Roos MT, Klein MR, Danner SA, Miedema F. Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection. Immunol Lett 1999;66:213-217. (Pubitemid 29136841)
    • (1999) Immunology Letters , vol.66 , Issue.1-3 , pp. 213-217
    • Pontesilli, O.1    Kerkhof-Garde, S.2    Pakker, N.G.3    Notermans, D.W.4    Roos, M.T.L.5    Klein, M.R.6    Danner, S.A.7    Miedema, F.8
  • 60
    • 33646679177 scopus 로고    scopus 로고
    • Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART
    • DOI 10.1097/01.aids.0000218545.31716.a4, PII 0000203020060404000005
    • Sutherland R, Yang H, Scriba TJ, Ondondo B, Robinson N, Conlon C, Suttill A, McShane H, Fidler S, McMichael A, et al. Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART. AIDS 2006;20:821-829. (Pubitemid 43731563)
    • (2006) AIDS , vol.20 , Issue.6 , pp. 821-829
    • Sutherland, R.1    Yang, H.2    Scriba, T.J.3    Ondondo, B.4    Robinson, N.5    Conlon, C.6    Suttill, A.7    McShane, H.8    Fidler, S.9    McMichael, A.10    Dorrell, L.11
  • 61
    • 34548485563 scopus 로고    scopus 로고
    • Deficient in vitro anti-mycobacterial immunity despite successful long-term highly active antiretroviral therapy in HIV-infected patients with past history of tuberculosis infection or disease
    • DOI 10.1016/j.clim.2007.06.002, PII S1521661607012508
    • Mendonca M, Tanji MM, Silva LC, Silveira GG, Oliveira SC, Duarte AJ, Benard G. Deficient in vitro anti-mycobacterial immunity despite successful long-term highly active antiretroviral therapy in HIV-infected patients with past history of tuberculosis infection or disease. Clin Immunol 2007;125:60-66. (Pubitemid 47376923)
    • (2007) Clinical Immunology , vol.125 , Issue.1 , pp. 60-66
    • Mendonca, M.1    Tanji, M.M.2    Silva, L.C.R.3    Silveira, G.G.4    Oliveira, S.C.5    Duarte, A.J.S.6    Benard, G.7
  • 62
    • 33745746961 scopus 로고    scopus 로고
    • Tuberculosis control in South Africa - Will HAART help?
    • Lawn SD, Wood R. Tuberculosis control in South Africa - will HAART help? S Afr Med J 2006;96:502-504.
    • (2006) S Afr Med J , vol.96 , pp. 502-504
    • Lawn, S.D.1    Wood, R.2
  • 63
    • 27944451480 scopus 로고    scopus 로고
    • Tuberculosis among HIV-infected patients receiving HAART: Long term incidence and risk factors in a South African cohort
    • Lawn SD, Badri M, Wood R. Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort. AIDS 2005;19:2109-2116. (Pubitemid 41668999)
    • (2005) AIDS , vol.19 , Issue.18 , pp. 2109-2116
    • Lawn, S.D.1    Badri, M.2    Wood, R.3
  • 64
    • 0030801512 scopus 로고    scopus 로고
    • Pathways of T-cell regeneration in mice and humans: Implications for bone marrow transplantation and immunotherapy
    • Mackall CL, Gress RE. Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy. Immunol Rev 1997;157:61-72.
    • (1997) Immunol Rev , vol.157 , pp. 61-72
    • Mackall, C.L.1    Gress, R.E.2
  • 67
    • 52049086987 scopus 로고    scopus 로고
    • The contribution of the thymus to the recovery of peripheral naive T-cell numbers during antiretroviral treatment for HIV infection
    • Ribeiro RM, de Boer RJ. The contribution of the thymus to the recovery of peripheral naive T-cell numbers during antiretroviral treatment for HIV infection. J Acquir Immune Defic Syndr 2008;49:1-8.
    • (2008) J Acquir Immune Defic Syndr , vol.49 , pp. 1-8
    • Ribeiro, R.M.1    De Boer, R.J.2
  • 69
    • 35748956419 scopus 로고    scopus 로고
    • Enhanced ex vivo stimulation of mycobacterium tuberculosis-specific T cells in HIV-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector
    • Connell TG, Shey MS, Seldon R, Rangaka MX, van Cutsem G, Simsova M, Marcekova Z, Sebo P, Curtis N, Diwakar L, et al. Enhanced ex vivo stimulation of mycobacterium tuberculosis-specific T cells in HIV-infected persons via antigen delivery by the Bordetella pertussis adenylate cyclase vector. Clin Vaccine Immunol 2007;14:847-854.
    • (2007) Clin Vaccine Immunol , vol.14 , pp. 847-854
    • Connell, T.G.1    Shey, M.S.2    Seldon, R.3    Rangaka, M.X.4    Van Cutsem, G.5    Simsova, M.6    Marcekova, Z.7    Sebo, P.8    Curtis, N.9    Diwakar, L.10
  • 71
    • 0035500638 scopus 로고    scopus 로고
    • Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in mycobacterium tuberculosis-infected individuals: Associations with clinical disease state and effect of treatment
    • Pathan AA, Wilkinson KA, Klenerman P, McShane H, Davidson RN, Pasvol G, Hill AV, Lalvani A. Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment. J Immunol 2001;167:5217-5225. (Pubitemid 33009758)
    • (2001) Journal of Immunology , vol.167 , Issue.9 , pp. 5217-5225
    • Pathan, A.A.1    Wilkinson, K.A.2    Klenerman, P.3    McShane, H.4    Davidson, R.N.5    Pasvol, G.6    Hill, A.V.S.7    Lalvani, A.8
  • 74
    • 42549163830 scopus 로고    scopus 로고
    • Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons
    • DOI 10.1086/529048
    • Day CL, Mkhwanazi N, Reddy S, Mncube Z, van der Stok M, Klenerman P, Walker BD. Detection of polyfunctional mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons. J Infect Dis 2008;197:990-999. (Pubitemid 351590027)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.7 , pp. 990-999
    • Day, C.L.1    Mkhwanazi, N.2    Reddy, S.3    Mncube, Z.4    Van Der Stok, M.5    Klenerman, P.6    Walker, B.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.