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Volumn 8, Issue 5, 2012, Pages

Vaccines against tuberculosis: Where are we and where do we need to go?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B7 ANTIGEN; BCG VACCINE; CD137 ANTIGEN; CD27 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 22; INTERLEUKIN 23; LIVE VACCINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84863690353     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002607     Document Type: Review
Times cited : (396)

References (145)
  • 1
    • 68149098007 scopus 로고    scopus 로고
    • Overcoming the global crisis: "yes, we can", but also for TB...?
    • Ottenhoff TH, (2009) Overcoming the global crisis: "yes, we can", but also for TB...? Eur J Immunol 39: 2014-2020.
    • (2009) Eur J Immunol , vol.39 , pp. 2014-2020
    • Ottenhoff, T.H.1
  • 2
    • 27544505415 scopus 로고    scopus 로고
    • From bacteriology to immunology: the dualism of specificity
    • Kaufmann SH, Winau F, (2005) From bacteriology to immunology: the dualism of specificity. Nat Immunol 6: 1063-1066.
    • (2005) Nat Immunol , vol.6 , pp. 1063-1066
    • Kaufmann, S.H.1    Winau, F.2
  • 3
  • 5
    • 77952542701 scopus 로고    scopus 로고
    • Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
    • Gandhi NR, Nunn P, Dheda K, Schaaf HS, Zignol M, et al. (2010) Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis. Lancet 375: 1830-1843.
    • (2010) Lancet , vol.375 , pp. 1830-1843
    • Gandhi, N.R.1    Nunn, P.2    Dheda, K.3    Schaaf, H.S.4    Zignol, M.5
  • 6
    • 68849127471 scopus 로고    scopus 로고
    • Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in iran
    • Velayati AA, Masjedi MR, Farnia P, Tabarsi P, Ghanavi J, et al. (2009) Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in iran. Chest 136: 420-425.
    • (2009) Chest , vol.136 , pp. 420-425
    • Velayati, A.A.1    Masjedi, M.R.2    Farnia, P.3    Tabarsi, P.4    Ghanavi, J.5
  • 7
    • 0003552576 scopus 로고
    • La vaccination préventive contre la tuberculose par le "BCG"
    • Calmette A, Guérin C, Boquet A, Négre L, (1927) La vaccination préventive contre la tuberculose par le "BCG". Masson.
    • (1927) Masson
    • Calmette, A.1    Guérin, C.2    Boquet, A.3    Négre, L.4
  • 9
    • 33847723035 scopus 로고    scopus 로고
    • Changing funding patterns in tuberculosis
    • Kaufmann SH, Parida SK, (2007) Changing funding patterns in tuberculosis. Nat Med 13: 299-303.
    • (2007) Nat Med , vol.13 , pp. 299-303
    • Kaufmann, S.H.1    Parida, S.K.2
  • 10
    • 0032508046 scopus 로고    scopus 로고
    • Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
    • Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
    • (1998) Nature , vol.393 , pp. 537-544
    • Cole, S.T.1    Brosch, R.2    Parkhill, J.3    Garnier, T.4    Churcher, C.5
  • 11
    • 2342584774 scopus 로고    scopus 로고
    • Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: a 60-year follow-up study
    • Aronson NE, Santosham M, Comstock GW, Howard RS, Moulton LH, et al. (2004) Long-term efficacy of BCG vaccine in American Indians and Alaska Natives: a 60-year follow-up study. JAMA 291: 2086-2091.
    • (2004) JAMA , vol.291 , pp. 2086-2091
    • Aronson, N.E.1    Santosham, M.2    Comstock, G.W.3    Howard, R.S.4    Moulton, L.H.5
  • 12
    • 33845197461 scopus 로고    scopus 로고
    • The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children
    • Hesseling AC, Marais BJ, Gie RP, Schaaf HS, Fine PE, et al. (2007) The risk of disseminated Bacille Calmette-Guerin (BCG) disease in HIV-infected children. Vaccine 25: 14-18.
    • (2007) Vaccine , vol.25 , pp. 14-18
    • Hesseling, A.C.1    Marais, B.J.2    Gie, R.P.3    Schaaf, H.S.4    Fine, P.E.5
  • 13
    • 0036727746 scopus 로고    scopus 로고
    • Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae
    • Ottenhoff TH, Verreck FA, Lichtenauer-Kaligis EG, Hoeve MA, Sanal O, et al. (2002) Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae. Nat Genet 32: 97-105.
    • (2002) Nat Genet , vol.32 , pp. 97-105
    • Ottenhoff, T.H.1    Verreck, F.A.2    Lichtenauer-Kaligis, E.G.3    Hoeve, M.A.4    Sanal, O.5
  • 14
    • 9644265521 scopus 로고    scopus 로고
    • Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae
    • Vosse Evd, Hoeve MA, Ottenhoff TH, (2004) Human genetics of intracellular infectious diseases: molecular and cellular immunity against mycobacteria and salmonellae. Lancet Infect Dis 4: 739-749.
    • (2004) Lancet Infect Dis , vol.4 , pp. 739-749
    • Vosse, E.1    Hoeve, M.A.2    Ottenhoff, T.H.3
  • 15
    • 33750874082 scopus 로고    scopus 로고
    • The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guerin vaccination in southern England and northern Malawi
    • Weir RE, Black GF, Nazareth B, Floyd S, Stenson S, et al. (2006) The influence of previous exposure to environmental mycobacteria on the interferon-gamma response to bacille Calmette-Guerin vaccination in southern England and northern Malawi. Clin Exp Immunol 146: 390-399.
    • (2006) Clin Exp Immunol , vol.146 , pp. 390-399
    • Weir, R.E.1    Black, G.F.2    Nazareth, B.3    Floyd, S.4    Stenson, S.5
  • 16
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
    • Barry CE III, Boshoff HI, Dartois V, Dick T, Ehrt S, et al. (2009) The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat Rev Microbiol 7: 845-855.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 845-855
    • Barry III, C.E.1    Boshoff, H.I.2    Dartois, V.3    Dick, T.4    Ehrt, S.5
  • 17
    • 73349135673 scopus 로고    scopus 로고
    • Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
    • Cobat A, Gallant CJ, Simkin L, Black GF, Stanley K, et al. (2009) Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis. J Exp Med 206: 2583-2591.
    • (2009) J Exp Med , vol.206 , pp. 2583-2591
    • Cobat, A.1    Gallant, C.J.2    Simkin, L.3    Black, G.F.4    Stanley, K.5
  • 19
    • 0036311078 scopus 로고    scopus 로고
    • Persistent high incidence of tuberculosis in immigrants in a low-incidence country
    • Lillebaek T, Andersen AB, Dirksen A, Smith E, Skovgaard LT, et al. (2002) Persistent high incidence of tuberculosis in immigrants in a low-incidence country. Emerg Infect Dis 8: 679-684.
    • (2002) Emerg Infect Dis , vol.8 , pp. 679-684
    • Lillebaek, T.1    Andersen, A.B.2    Dirksen, A.3    Smith, E.4    Skovgaard, L.T.5
  • 20
    • 0012746992 scopus 로고    scopus 로고
    • The growing burden of tuberculosis: global trends and interactions with the HIV epidemic
    • Corbett EL, Watt CJ, Walker N, Maher D, Williams BG, et al. (2003) The growing burden of tuberculosis: global trends and interactions with the HIV epidemic. Arch Intern Med 163: 1009-1021.
    • (2003) Arch Intern Med , vol.163 , pp. 1009-1021
    • Corbett, E.L.1    Watt, C.J.2    Walker, N.3    Maher, D.4    Williams, B.G.5
  • 21
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
    • Keane J, Gershon S, Wise RP, Mirabile-Levens E, Kasznica J, et al. (2001) Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 345: 1098-104.
    • (2001) N Engl J Med , vol.345 , pp. 1098-1104
    • Keane, J.1    Gershon, S.2    Wise, R.P.3    Mirabile-Levens, E.4    Kasznica, J.5
  • 22
    • 77951091847 scopus 로고    scopus 로고
    • New and improved tuberculosis diagnostics: evidence, policy, practice, and impact
    • Pai M, Minion J, Steingart K, Ramsay A, (2010) New and improved tuberculosis diagnostics: evidence, policy, practice, and impact. Curr Opin Pulm Med 16: 271-284.
    • (2010) Curr Opin Pulm Med , vol.16 , pp. 271-284
    • Pai, M.1    Minion, J.2    Steingart, K.3    Ramsay, A.4
  • 23
    • 75149133148 scopus 로고    scopus 로고
    • The quest for biomarkers in tuberculosis
    • Parida SK, Kaufmann SH, (2010) The quest for biomarkers in tuberculosis. Drug Discov Today 15: 148-157.
    • (2010) Drug Discov Today , vol.15 , pp. 148-157
    • Parida, S.K.1    Kaufmann, S.H.2
  • 24
    • 34547624348 scopus 로고    scopus 로고
    • Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis
    • Mittrucker HW, Steinhoff U, Kohler A, Krause M, Lazar D, et al. (2007) Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis. Proc Natl Acad Sci U S A 104: 12434-12439.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12434-12439
    • Mittrucker, H.W.1    Steinhoff, U.2    Kohler, A.3    Krause, M.4    Lazar, D.5
  • 25
    • 77958481160 scopus 로고    scopus 로고
    • Future vaccination strategies against tuberculosis: thinking outside the box
    • Kaufmann SH, (2010) Future vaccination strategies against tuberculosis: thinking outside the box. Immunity 33: 567-577.
    • (2010) Immunity , vol.33 , pp. 567-577
    • Kaufmann, S.H.1
  • 26
    • 78650088377 scopus 로고    scopus 로고
    • The global plan to stop TB 2011-2015
    • Stop TB Partnership Working Group on New TB Vaccines 2, Stop TB Partnership
    • Stop TB Partnership Working Group on New TB Vaccines 2 (2010) The global plan to stop TB 2011-2015. Stop TB Partnership.
    • (2010)
  • 27
    • 79958724193 scopus 로고    scopus 로고
    • Treatment of multi-drug-resistant tuberculosis in mice with DNA vaccines alone or in combination with chemotherapeutic drugs
    • Liang Y, Wu X, Zhang J, Yang Y, Wang L, et al. (2011) Treatment of multi-drug-resistant tuberculosis in mice with DNA vaccines alone or in combination with chemotherapeutic drugs. Scand J Immunol 74: 42-46.
    • (2011) Scand J Immunol , vol.74 , pp. 42-46
    • Liang, Y.1    Wu, X.2    Zhang, J.3    Yang, Y.4    Wang, L.5
  • 28
    • 22944433876 scopus 로고    scopus 로고
    • The success and failure of BCG - implications for a novel tuberculosis vaccine
    • Andersen P, Doherty TM, (2005) The success and failure of BCG- implications for a novel tuberculosis vaccine. Nat Rev Microbiol 3: 656-62.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 656-662
    • Andersen, P.1    Doherty, T.M.2
  • 29
    • 67650257191 scopus 로고    scopus 로고
    • The potential impact of helminth infection on trials of novel tuberculosis vaccines
    • Hatherill M, Adams V, Hughes J, de KM, Mavakla W, et al. (2009) The potential impact of helminth infection on trials of novel tuberculosis vaccines. Vaccine 27: 4743-4744.
    • (2009) Vaccine , vol.27 , pp. 4743-4744
    • Hatherill, M.1    Adams, V.2    Hughes, J.3    de, K.M.4    Mavakla, W.5
  • 30
    • 80052086428 scopus 로고    scopus 로고
    • Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway
    • Potian JA, Rafi W, Bhatt K, McBride A, Gause WC, et al. (2011) Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway. J Exp Med 208: 1863-1874.
    • (2011) J Exp Med , vol.208 , pp. 1863-1874
    • Potian, J.A.1    Rafi, W.2    Bhatt, K.3    McBride, A.4    Gause, W.C.5
  • 31
    • 79955101596 scopus 로고    scopus 로고
    • Initiation and regulation of T-cell responses in tuberculosis
    • Urdahl KB, Shafiani S, Ernst JD, (2011) Initiation and regulation of T-cell responses in tuberculosis. Mucosal Immunol 4: 288-293.
    • (2011) Mucosal Immunol , vol.4 , pp. 288-293
    • Urdahl, K.B.1    Shafiani, S.2    Ernst, J.D.3
  • 32
    • 38749138163 scopus 로고    scopus 로고
    • Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
    • Wolf AJ, Desvignes L, Linas B, Banaiee N, Tamura T, et al. (2008) Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med 205: 105-115.
    • (2008) J Exp Med , vol.205 , pp. 105-115
    • Wolf, A.J.1    Desvignes, L.2    Linas, B.3    Banaiee, N.4    Tamura, T.5
  • 33
    • 49449098413 scopus 로고    scopus 로고
    • ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
    • Reiley WW, Calayag MD, Wittmer ST, Huntington JL, Pearl JE, et al. (2008) ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes. Proc Natl Acad Sci U S A 105: 10961-10966.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10961-10966
    • Reiley, W.W.1    Calayag, M.D.2    Wittmer, S.T.3    Huntington, J.L.4    Pearl, J.E.5
  • 34
    • 53349118087 scopus 로고    scopus 로고
    • Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection
    • Gallegos AM, Pamer EG, Glickman MS, (2008) Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection. J Exp Med 205: 2359-2368.
    • (2008) J Exp Med , vol.205 , pp. 2359-2368
    • Gallegos, A.M.1    Pamer, E.G.2    Glickman, M.S.3
  • 35
    • 31144446585 scopus 로고    scopus 로고
    • New insights into the function of granulomas in human tuberculosis
    • Ulrichs T, Kaufmann SH, (2006) New insights into the function of granulomas in human tuberculosis. J Pathol 208: 261-269.
    • (2006) J Pathol , vol.208 , pp. 261-269
    • Ulrichs, T.1    Kaufmann, S.H.2
  • 36
    • 77953316728 scopus 로고    scopus 로고
    • Secondary lymphoid organs are dispensable for the development of T-cell-mediated immunity during tuberculosis
    • Day TA, Koch M, Nouailles G, Jacobsen M, Kosmiadi GA, et al. (2010) Secondary lymphoid organs are dispensable for the development of T-cell-mediated immunity during tuberculosis. Eur J Immunol 40: 1663-1673.
    • (2010) Eur J Immunol , vol.40 , pp. 1663-1673
    • Day, T.A.1    Koch, M.2    Nouailles, G.3    Jacobsen, M.4    Kosmiadi, G.A.5
  • 37
    • 33745812070 scopus 로고    scopus 로고
    • Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
    • Khader SA, Partida-Sanchez S, Bell G, Jelley-Gibbs DM, Swain S, et al. (2006) Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med 203: 1805-1815.
    • (2006) J Exp Med , vol.203 , pp. 1805-1815
    • Khader, S.A.1    Partida-Sanchez, S.2    Bell, G.3    Jelley-Gibbs, D.M.4    Swain, S.5
  • 38
    • 84856083753 scopus 로고    scopus 로고
    • Floating between the poles of pathology and protection: can we pin down the granuloma in tuberculosis?
    • Reece ST, Kaufmann SH, (2012) Floating between the poles of pathology and protection: can we pin down the granuloma in tuberculosis? Curr Opin Microbiol 15: 63-70.
    • (2012) Curr Opin Microbiol , vol.15 , pp. 63-70
    • Reece, S.T.1    Kaufmann, S.H.2
  • 39
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, et al. (2004) Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119: 753-766.
    • (2004) Cell , vol.119 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5
  • 40
    • 33745357459 scopus 로고    scopus 로고
    • Autophagy as an immune defense mechanism
    • Deretic V, (2006) Autophagy as an immune defense mechanism. Curr Opin Immunol 18: 375-382.
    • (2006) Curr Opin Immunol , vol.18 , pp. 375-382
    • Deretic, V.1
  • 41
    • 34548591486 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the environment within the phagosome
    • Rohde K, Yates RM, Purdy GE, Russell DG, (2007) Mycobacterium tuberculosis and the environment within the phagosome. Immunol Rev 219: 37-54.
    • (2007) Immunol Rev , vol.219 , pp. 37-54
    • Rohde, K.1    Yates, R.M.2    Purdy, G.E.3    Russell, D.G.4
  • 42
    • 33846818409 scopus 로고    scopus 로고
    • Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment
    • Sahiratmadja E, Alisjahbana B, de BT, Adnan I, Maya A, et al. (2007) Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment. Infect Immun 75: 820-829.
    • (2007) Infect Immun , vol.75 , pp. 820-829
    • Sahiratmadja, E.1    Alisjahbana, B.2    de, B.T.3    Adnan, I.4    Maya, A.5
  • 43
    • 34250716965 scopus 로고    scopus 로고
    • M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells
    • van der Wel N, Hava D, Houben D, Fluitsma D, van ZM, et al. (2007) M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129: 1287-1298.
    • (2007) Cell , vol.129 , pp. 1287-1298
    • van der Wel, N.1    Hava, D.2    Houben, D.3    Fluitsma, D.4    van, Z.M.5
  • 44
    • 79951899229 scopus 로고    scopus 로고
    • For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection
    • Dorhoi A, Reece ST, Kaufmann SH, (2011) For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection. Immunol Rev 240: 235-251.
    • (2011) Immunol Rev , vol.240 , pp. 235-251
    • Dorhoi, A.1    Reece, S.T.2    Kaufmann, S.H.3
  • 45
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: the human model
    • Casanova JL, Abel L, (2002) Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 20: 581-620.
    • (2002) Annu Rev Immunol , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 46
    • 0023000278 scopus 로고
    • Molecular localization and polymorphism of HLA class II restriction determinants defined by Mycobacterium leprae-reactive helper T cell clones from leprosy patients
    • Ottenhoff TH, Neuteboom S, Elferink DG, de Vries RR, (1986) Molecular localization and polymorphism of HLA class II restriction determinants defined by Mycobacterium leprae-reactive helper T cell clones from leprosy patients. J Exp Med 164: 1923-1939.
    • (1986) J Exp Med , vol.164 , pp. 1923-1939
    • Ottenhoff, T.H.1    Neuteboom, S.2    Elferink, D.G.3    de Vries, R.R.4
  • 47
    • 0026516797 scopus 로고
    • Binding of a major T cell epitope of mycobacteria to a specific pocket within HLA-DRw17(DR3) molecules
    • Geluk A, Bloemhoff W, de Vries RR, Ottenhoff TH, (1992) Binding of a major T cell epitope of mycobacteria to a specific pocket within HLA-DRw17(DR3) molecules. Eur J Immunol 22: 107-113.
    • (1992) Eur J Immunol , vol.22 , pp. 107-113
    • Geluk, A.1    Bloemhoff, W.2    de Vries, R.R.3    Ottenhoff, T.H.4
  • 48
    • 0028987317 scopus 로고
    • Immune response to Mycobacterium bovis bacille Calmette Guerin infection in major histocompatibility complex class I- and II-deficient knock-out mice: contribution of CD4 and CD8 T cells to acquired resistance
    • Ladel CH, Daugelat S, Kaufmann SH, (1995) Immune response to Mycobacterium bovis bacille Calmette Guerin infection in major histocompatibility complex class I- and II-deficient knock-out mice: contribution of CD4 and CD8 T cells to acquired resistance. Eur J Immunol 25: 377-384.
    • (1995) Eur J Immunol , vol.25 , pp. 377-384
    • Ladel, C.H.1    Daugelat, S.2    Kaufmann, S.H.3
  • 49
    • 79956302280 scopus 로고    scopus 로고
    • Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas
    • Egen JG, Rothfuchs AG, Feng CG, Horwitz MA, Sher A, et al. (2011) Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity 34: 807-819.
    • (2011) Immunity , vol.34 , pp. 807-819
    • Egen, J.G.1    Rothfuchs, A.G.2    Feng, C.G.3    Horwitz, M.A.4    Sher, A.5
  • 50
    • 70249100293 scopus 로고    scopus 로고
    • Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity
    • Sallusto F, Lanzavecchia A, (2009) Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity. Eur J Immunol 39: 2076-2082.
    • (2009) Eur J Immunol , vol.39 , pp. 2076-2082
    • Sallusto, F.1    Lanzavecchia, A.2
  • 51
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, et al. (2007) IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 8: 369-377.
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1    Bell, G.K.2    Pearl, J.E.3    Fountain, J.J.4    Rangel-Moreno, J.5
  • 52
    • 67650932256 scopus 로고    scopus 로고
    • Cell-mediated immune responses in tuberculosis
    • Cooper AM, (2009) Cell-mediated immune responses in tuberculosis. Annu Rev Immunol 27: 393-422.
    • (2009) Annu Rev Immunol , vol.27 , pp. 393-422
    • Cooper, A.M.1
  • 53
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel-Moreno J, et al. (2007) IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 8: 369-377.
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1    Bell, G.K.2    Pearl, J.E.3    Fountain, J.J.4    Rangel-Moreno, J.5
  • 54
    • 77952774172 scopus 로고    scopus 로고
    • Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung
    • Okamoto YY, Umemura M, Yahagi A, O'Brien RL, Ikuta K, et al. (2010) Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung. J Immunol 184: 4414-4422.
    • (2010) J Immunol , vol.184 , pp. 4414-4422
    • Okamoto, Y.Y.1    Umemura, M.2    Yahagi, A.3    O'Brien, R.L.4    Ikuta, K.5
  • 55
    • 77955390095 scopus 로고    scopus 로고
    • Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis
    • Cruz A, Fraga AG, Fountain JJ, Rangel-Moreno J, Torrado E, et al. (2010) Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. J Exp Med 207: 1609-1616.
    • (2010) J Exp Med , vol.207 , pp. 1609-1616
    • Cruz, A.1    Fraga, A.G.2    Fountain, J.J.3    Rangel-Moreno, J.4    Torrado, E.5
  • 56
    • 79751529842 scopus 로고    scopus 로고
    • Cellular response to mycobacteria: balancing protection and pathology
    • Torrado E, Robinson RT, Cooper AM, (2011) Cellular response to mycobacteria: balancing protection and pathology. Trends Immunol 32: 66-72.
    • (2011) Trends Immunol , vol.32 , pp. 66-72
    • Torrado, E.1    Robinson, R.T.2    Cooper, A.M.3
  • 57
    • 77958189493 scopus 로고    scopus 로고
    • Human CD4 and CD8 T cell responses to Mycobacterium tuberculosis: antigen specificity, function, implications and applications
    • Weinheim, Germany, Wiley-VCH Verlag GmbH & Co.KGaA
    • Ottenhoff TH, Lewinsohn DA, Lewinsohn DM, (2008) Human CD4 and CD8 T cell responses to Mycobacterium tuberculosis: antigen specificity, function, implications and applications. Handbook of tuberculosis. Immunology and cell biology Weinheim, Germany Wiley-VCH Verlag GmbH & Co.KGaA pp. 119-156.
    • (2008) Handbook of Tuberculosis. Immunology and Cell Biology , pp. 119-156
    • Ottenhoff, T.H.1    Lewinsohn, D.A.2    Lewinsohn, D.M.3
  • 58
    • 0041965927 scopus 로고    scopus 로고
    • Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis
    • Schaible UE, Winau F, Sieling PA, Fischer K, Collins HL, et al. (2003) Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Nat Med 9: 1039-1046.
    • (2003) Nat Med , vol.9 , pp. 1039-1046
    • Schaible, U.E.1    Winau, F.2    Sieling, P.A.3    Fischer, K.4    Collins, H.L.5
  • 59
    • 30444457915 scopus 로고    scopus 로고
    • Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
    • Winau F, Weber S, Sad S, de DJ, Hoops SL, et al. (2006) Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis. Immunity 24: 105-117.
    • (2006) Immunity , vol.24 , pp. 105-117
    • Winau, F.1    Weber, S.2    Sad, S.3    de, D.J.4    Hoops, S.L.5
  • 60
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine B, Mizushima N, Virgin HW, (2011) Autophagy in immunity and inflammation. Nature 469: 323-335.
    • (2011) Nature , vol.469 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 61
    • 77951256153 scopus 로고    scopus 로고
    • Autophagy in infection
    • Deretic V, (2010) Autophagy in infection. Curr Opin Cell Biol 22: 252-262.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 252-262
    • Deretic, V.1
  • 62
    • 0034743547 scopus 로고    scopus 로고
    • MHC class Ia-restricted T cells partially account for beta2-microglobulin-dependent resistance to Mycobacterium tuberculosis
    • Rolph MS, Raupach B, Kobernick HH, Collins HL, Perarnau B, et al. (2001) MHC class Ia-restricted T cells partially account for beta2-microglobulin-dependent resistance to Mycobacterium tuberculosis. Eur J Immunol 31: 1944-1949.
    • (2001) Eur J Immunol , vol.31 , pp. 1944-1949
    • Rolph, M.S.1    Raupach, B.2    Kobernick, H.H.3    Collins, H.L.4    Perarnau, B.5
  • 63
    • 0037011071 scopus 로고    scopus 로고
    • Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis
    • Schaible UE, Collins HL, Priem F, Kaufmann SH, (2002) Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. J Exp Med 196: 1507-1513.
    • (2002) J Exp Med , vol.196 , pp. 1507-1513
    • Schaible, U.E.1    Collins, H.L.2    Priem, F.3    Kaufmann, S.H.4
  • 64
    • 77649260171 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity
    • 10.1371/journal.ppat.1000782
    • Joosten SA, van Meijgaarden KE, van Weeren PC, Kazi F, Geluk A, et al. (2010) Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity. PLoS Pathog 6: e1000782 doi:10.1371/journal.ppat.1000782.
    • (2010) PLoS Pathog , vol.6
    • Joosten, S.A.1    van Meijgaarden, K.E.2    van Weeren, P.C.3    Kazi, F.4    Geluk, A.5
  • 65
    • 0037011066 scopus 로고    scopus 로고
    • HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells
    • Heinzel AS, Grotzke JE, Lines RA, Lewinsohn DA, McNabb AL, et al. (2002) HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells. J Exp Med 196: 1473-1481.
    • (2002) J Exp Med , vol.196 , pp. 1473-1481
    • Heinzel, A.S.1    Grotzke, J.E.2    Lines, R.A.3    Lewinsohn, D.A.4    McNabb, A.L.5
  • 66
    • 77954701928 scopus 로고    scopus 로고
    • Human mucosal associated invariant T cells detect bacterially infected cells
    • 10.1371/journal.pbio.1000407
    • Gold MC, Cerri S, Smyk-Pearson S, Cansler ME, Vogt TM, et al. (2010) Human mucosal associated invariant T cells detect bacterially infected cells. PLoS Biol 8: e1000407 doi:10.1371/journal.pbio.1000407.
    • (2010) PLoS Biol , vol.8
    • Gold, M.C.1    Cerri, S.2    Smyk-Pearson, S.3    Cansler, M.E.4    Vogt, T.M.5
  • 67
    • 0034502343 scopus 로고    scopus 로고
    • Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection
    • Hernandez-Pando R, Jeyanathan M, Mengistu G, Aguilar D, Orozco H, et al. (2000) Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 356: 2133-2138.
    • (2000) Lancet , vol.356 , pp. 2133-2138
    • Hernandez-Pando, R.1    Jeyanathan, M.2    Mengistu, G.3    Aguilar, D.4    Orozco, H.5
  • 68
    • 0034651738 scopus 로고    scopus 로고
    • Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages
    • Keane J, Remold HG, Kornfeld H, (2000) Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages. J Immunol 164: 2016-2020.
    • (2000) J Immunol , vol.164 , pp. 2016-2020
    • Keane, J.1    Remold, H.G.2    Kornfeld, H.3
  • 69
    • 0032475823 scopus 로고    scopus 로고
    • An antimicrobial activity of cytolytic T cells mediated by granulysin
    • Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, et al. (1998) An antimicrobial activity of cytolytic T cells mediated by granulysin. Science 282: 121-125.
    • (1998) Science , vol.282 , pp. 121-125
    • Stenger, S.1    Hanson, D.A.2    Teitelbaum, R.3    Dewan, P.4    Niazi, K.R.5
  • 70
    • 33746214785 scopus 로고    scopus 로고
    • Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens
    • Caccamo N, Meraviglia S, La MC, Guggino G, Dieli F, et al. (2006) Phenotypical and functional analysis of memory and effector human CD8 T cells specific for mycobacterial antigens. J Immunol 177: 1780-1785.
    • (2006) J Immunol , vol.177 , pp. 1780-1785
    • Caccamo, N.1    Meraviglia, S.2    La, M.C.3    Guggino, G.4    Dieli, F.5
  • 71
    • 77956928418 scopus 로고    scopus 로고
    • TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice
    • Tang H, Pang S, Wang M, Xiao X, Rong Y, et al. (2010) TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol 185: 2563-2569.
    • (2010) J Immunol , vol.185 , pp. 2563-2569
    • Tang, H.1    Pang, S.2    Wang, M.3    Xiao, X.4    Rong, Y.5
  • 72
    • 77958475885 scopus 로고    scopus 로고
    • Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns
    • Kagina BM, Abel B, Scriba TJ, Hughes EJ, Keyser A, et al. (2010) Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guerin vaccination of newborns. Am J Respir Crit Care Med 182: 1073-1079.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1073-1079
    • Kagina, B.M.1    Abel, B.2    Scriba, T.J.3    Hughes, E.J.4    Keyser, A.5
  • 73
    • 74549183647 scopus 로고    scopus 로고
    • Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501, and DRB1*0401
    • Gaseitsiwe S, Valentini D, Mahdavifar S, Reilly M, Ehrnst A, et al. (2010) Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501, and DRB1*0401. Clin Vaccine Immunol 17: 168-175.
    • (2010) Clin Vaccine Immunol , vol.17 , pp. 168-175
    • Gaseitsiwe, S.1    Valentini, D.2    Mahdavifar, S.3    Reilly, M.4    Ehrnst, A.5
  • 74
    • 34848873722 scopus 로고    scopus 로고
    • Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B
    • 10.1371/journal.ppat.0030127
    • Lewinsohn DA, Winata E, Swarbrick GM, Tanner KE, Cook MS, et al. (2007) Immunodominant tuberculosis CD8 antigens preferentially restricted by HLA-B. PLoS Pathog 3: e127 doi:10.1371/journal.ppat.0030127.
    • (2007) PLoS Pathog , vol.3
    • Lewinsohn, D.A.1    Winata, E.2    Swarbrick, G.M.3    Tanner, K.E.4    Cook, M.S.5
  • 75
    • 79954486176 scopus 로고    scopus 로고
    • Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals
    • Commandeur S, van Meijgaarden KE, Lin MY, Franken KL, Friggen AH, et al. (2011) Identification of human T-cell responses to Mycobacterium tuberculosis resuscitation-promoting factors in long-term latently infected individuals. Clin Vaccine Immunol 18: 676-683.
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 676-683
    • Commandeur, S.1    van Meijgaarden, K.E.2    Lin, M.Y.3    Franken, K.L.4    Friggen, A.H.5
  • 76
    • 64049113596 scopus 로고    scopus 로고
    • How B cells shape the immune response against Mycobacterium tuberculosis
    • Maglione PJ, Chan J, (2009) How B cells shape the immune response against Mycobacterium tuberculosis. Eur J Immunol 39: 676-686.
    • (2009) Eur J Immunol , vol.39 , pp. 676-686
    • Maglione, P.J.1    Chan, J.2
  • 77
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, et al. (2010) An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466: 973-977.
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.5
  • 78
    • 78751648792 scopus 로고    scopus 로고
    • Human gene expression profiles of susceptibility and resistance in tuberculosis
    • Maertzdorf J, Repsilber D, Parida SK, Stanley K, Roberts T, et al. (2011) Human gene expression profiles of susceptibility and resistance in tuberculosis. Genes Immun 12: 15-22.
    • (2011) Genes Immun , vol.12 , pp. 15-22
    • Maertzdorf, J.1    Repsilber, D.2    Parida, S.K.3    Stanley, K.4    Roberts, T.5
  • 79
    • 65849488547 scopus 로고    scopus 로고
    • Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection
    • 10.1371/journal.pone.0005528
    • Caccamo N, Guggino G, Meraviglia S, Gelsomino G, Di CP, et al. (2009) Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection. PLoS ONE 4: e5528 doi:10.1371/journal.pone.0005528.
    • (2009) PLoS ONE , vol.4
    • Caccamo, N.1    Guggino, G.2    Meraviglia, S.3    Gelsomino, G.4    Di, C.P.5
  • 80
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13: 843-850.
    • (2007) Nat Med , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    De Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5
  • 81
    • 79953189362 scopus 로고    scopus 로고
    • Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4 T cells
    • Derrick SC, Yabe IM, Yang A, Morris SL, (2011) Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4 T cells. Vaccine 29: 2902-2909.
    • (2011) Vaccine , vol.29 , pp. 2902-2909
    • Derrick, S.C.1    Yabe, I.M.2    Yang, A.3    Morris, S.L.4
  • 82
    • 64049095274 scopus 로고    scopus 로고
    • Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease
    • Sutherland JS, Adetifa IM, Hill PC, Adegbola RA, Ota MO, (2009) Pattern and diversity of cytokine production differentiates between Mycobacterium tuberculosis infection and disease. Eur J Immunol 39: 723-729.
    • (2009) Eur J Immunol , vol.39 , pp. 723-729
    • Sutherland, J.S.1    Adetifa, I.M.2    Hill, P.C.3    Adegbola, R.A.4    Ota, M.O.5
  • 83
    • 77956108181 scopus 로고    scopus 로고
    • Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection
    • Caccamo N, Guggino G, Joosten SA, Gelsomino G, Di CP, et al. (2010) Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 40: 2211-2220.
    • (2010) Eur J Immunol , vol.40 , pp. 2211-2220
    • Caccamo, N.1    Guggino, G.2    Joosten, S.A.3    Gelsomino, G.4    Di, C.P.5
  • 84
    • 77954288837 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
    • Smith SG, Lalor MK, Gorak-Stolinska P, Blitz R, Beveridge NE, et al. (2010) Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining. BMC Immunol 11: 35.
    • (2010) BMC Immunol , vol.11 , pp. 35
    • Smith, S.G.1    Lalor, M.K.2    Gorak-Stolinska, P.3    Blitz, R.4    Beveridge, N.E.5
  • 86
    • 77954390239 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
    • Shafiani S, Tucker-Heard G, Kariyone A, Takatsu K, Urdahl KB, (2010) Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis. J Exp Med 207: 1409-1420.
    • (2010) J Exp Med , vol.207 , pp. 1409-1420
    • Shafiani, S.1    Tucker-Heard, G.2    Kariyone, A.3    Takatsu, K.4    Urdahl, K.B.5
  • 87
    • 33847344205 scopus 로고    scopus 로고
    • Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis
    • Kursar M, Koch M, Mittrucker HW, Nouailles G, Bonhagen K, et al. (2007) Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. J Immunol 178: 2661-2665.
    • (2007) J Immunol , vol.178 , pp. 2661-2665
    • Kursar, M.1    Koch, M.2    Mittrucker, H.W.3    Nouailles, G.4    Bonhagen, K.5
  • 88
    • 34249944837 scopus 로고    scopus 로고
    • Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4
    • Joosten SA, van Meijgaarden KE, Savage ND, de BT, Triebel F, et al. (2007) Identification of a human CD8+ regulatory T cell subset that mediates suppression through the chemokine CC chemokine ligand 4. Proc Natl Acad Sci U S A 104: 8029-8034.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 8029-8034
    • Joosten, S.A.1    van Meijgaarden, K.E.2    Savage, N.D.3    de, B.T.4    Triebel, F.5
  • 89
    • 57649090701 scopus 로고    scopus 로고
    • Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination
    • Joosten SA, Ottenhoff TH, (2008) Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination. Hum Immunol 69: 760-770.
    • (2008) Hum Immunol , vol.69 , pp. 760-770
    • Joosten, S.A.1    Ottenhoff, T.H.2
  • 90
    • 78751676191 scopus 로고    scopus 로고
    • First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses
    • Ottenhoff TH, Doherty TM, van Dissel JT, Bang P, Lingnau K, et al. (2010) First in humans: a new molecularly defined vaccine shows excellent safety and strong induction of long-lived Mycobacterium tuberculosis-specific Th1-cell like responses. Hum Vaccin 6: 1007-1015.
    • (2010) Hum Vaccin , vol.6 , pp. 1007-1015
    • Ottenhoff, T.H.1    Doherty, T.M.2    van Dissel, J.T.3    Bang, P.4    Lingnau, K.5
  • 91
    • 3042769443 scopus 로고    scopus 로고
    • Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens
    • Brodin P, Majlessi L, Brosch R, Smith D, Bancroft G, et al. (2004) Enhanced protection against tuberculosis by vaccination with recombinant Mycobacterium microti vaccine that induces T cell immunity against region of difference 1 antigens. J Infect Dis 190: 115-122.
    • (2004) J Infect Dis , vol.190 , pp. 115-122
    • Brodin, P.1    Majlessi, L.2    Brosch, R.3    Smith, D.4    Bancroft, G.5
  • 92
    • 80053963965 scopus 로고    scopus 로고
    • A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
    • Sweeney KA, Dao DN, Goldberg MF, Hsu T, Venkataswamy MM, et al. (2011) A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis. Nat Med 17: 1261-1268.
    • (2011) Nat Med , vol.17 , pp. 1261-1268
    • Sweeney, K.A.1    Dao, D.N.2    Goldberg, M.F.3    Hsu, T.4    Venkataswamy, M.M.5
  • 93
    • 55849112610 scopus 로고    scopus 로고
    • A Replication-Limited Recombinant Mycobacterium bovis BCG vaccine against tuberculosis designed for human immunodeficiency virus-positive persons is safer and more efficacious than BCG
    • Tullius MV, Harth G, Maslesa-Galic S, Dillon BJ, Horwitz MA, (2008) A Replication-Limited Recombinant Mycobacterium bovis BCG vaccine against tuberculosis designed for human immunodeficiency virus-positive persons is safer and more efficacious than BCG. Infect Immun 76: 5200-5214.
    • (2008) Infect Immun , vol.76 , pp. 5200-5214
    • Tullius, M.V.1    Harth, G.2    Maslesa-Galic, S.3    Dillon, B.J.4    Horwitz, M.A.5
  • 94
    • 54949108635 scopus 로고    scopus 로고
    • A new recombinant bacille Calmette-Guerin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers
    • Hoft DF, Blazevic A, Abate G, Hanekom WA, Kaplan G, et al. (2008) A new recombinant bacille Calmette-Guerin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers. J Infect Dis 198: 1491-1501.
    • (2008) J Infect Dis , vol.198 , pp. 1491-1501
    • Hoft, D.F.1    Blazevic, A.2    Abate, G.3    Hanekom, W.A.4    Kaplan, G.5
  • 95
    • 0038751936 scopus 로고    scopus 로고
    • Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis
    • Pym AS, Brodin P, Majlessi L, Brosch R, Demangel C, et al. (2003) Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis. Nat Med 9: 533-539.
    • (2003) Nat Med , vol.9 , pp. 533-539
    • Pym, A.S.1    Brodin, P.2    Majlessi, L.3    Brosch, R.4    Demangel, C.5
  • 96
    • 67649321241 scopus 로고    scopus 로고
    • Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis
    • Sun R, Skeiky YA, Izzo A, Dheenadhayalan V, Imam Z, et al. (2009) Novel recombinant BCG expressing perfringolysin O and the over-expression of key immunodominant antigens; pre-clinical characterization, safety and protection against challenge with Mycobacterium tuberculosis. Vaccine 27: 4412-4423.
    • (2009) Vaccine , vol.27 , pp. 4412-4423
    • Sun, R.1    Skeiky, Y.A.2    Izzo, A.3    Dheenadhayalan, V.4    Imam, Z.5
  • 97
    • 22344433382 scopus 로고    scopus 로고
    • Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin
    • Grode L, Seiler P, Baumann S, Hess J, Brinkmann V, et al. (2005) Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin. J Clin Invest 115: 2472-2479.
    • (2005) J Clin Invest , vol.115 , pp. 2472-2479
    • Grode, L.1    Seiler, P.2    Baumann, S.3    Hess, J.4    Brinkmann, V.5
  • 98
    • 0034602312 scopus 로고    scopus 로고
    • A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity
    • Decatur AL, Portnoy DA, (2000) A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity. Science 290: 992-995.
    • (2000) Science , vol.290 , pp. 992-995
    • Decatur, A.L.1    Portnoy, D.A.2
  • 99
    • 0034877296 scopus 로고    scopus 로고
    • The family of thiol-activated, cholesterol-binding cytolysins
    • Palmer M, (2001) The family of thiol-activated, cholesterol-binding cytolysins. Toxicon 39: 1681-1689.
    • (2001) Toxicon , vol.39 , pp. 1681-1689
    • Palmer, M.1
  • 100
    • 61949472508 scopus 로고    scopus 로고
    • Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation
    • Torchinsky MB, Garaude J, Martin AP, Blander JM, (2009) Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation. Nature 458: 78-82.
    • (2009) Nature , vol.458 , pp. 78-82
    • Torchinsky, M.B.1    Garaude, J.2    Martin, A.P.3    Blander, J.M.4
  • 101
    • 80054745408 scopus 로고    scopus 로고
    • Recombinant BCG {Delta}ureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses
    • Desel C, Dorhoi A, Bandermann S, Grode L, Eisele B, et al. (2011) Recombinant BCG {Delta}ureC hly+ Induces Superior Protection Over Parental BCG by Stimulating a Balanced Combination of Type 1 and Type 17 Cytokine Responses. J Infect Dis 204: 1573-1584.
    • (2011) J Infect Dis , vol.204 , pp. 1573-1584
    • Desel, C.1    Dorhoi, A.2    Bandermann, S.3    Grode, L.4    Eisele, B.5
  • 102
    • 7044270950 scopus 로고    scopus 로고
    • Application of mycobacterial proteomics to vaccine design: improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis
    • Mollenkopf HJ, Grode L, Mattow J, Stein M, Mann P, et al. (2004) Application of mycobacterial proteomics to vaccine design: improved protection by Mycobacterium bovis BCG prime-Rv3407 DNA boost vaccination against tuberculosis. Infect Immun 72: 6471-6479.
    • (2004) Infect Immun , vol.72 , pp. 6471-6479
    • Mollenkopf, H.J.1    Grode, L.2    Mattow, J.3    Stein, M.4    Mann, P.5
  • 103
    • 83755163040 scopus 로고    scopus 로고
    • Infectious disease. Taking a new shot at a TB vaccine
    • Kupferschmidt K, (2011) Infectious disease. Taking a new shot at a TB vaccine. Science 334: 1488-1490.
    • (2011) Science , vol.334 , pp. 1488-1490
    • Kupferschmidt, K.1
  • 105
    • 33747371997 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis
    • Sambandamurthy VK, Derrick SC, Hsu T, Chen B, Larsen MH, et al. (2006) Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis. Vaccine 24: 6309-6320.
    • (2006) Vaccine , vol.24 , pp. 6309-6320
    • Sambandamurthy, V.K.1    Derrick, S.C.2    Hsu, T.3    Chen, B.4    Larsen, M.H.5
  • 106
    • 33645314357 scopus 로고    scopus 로고
    • The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs
    • Martin C, Williams A, Hernandez-Pando R, Cardona PJ, Gormley E, et al. (2006) The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs. Vaccine 24: 3408-3419.
    • (2006) Vaccine , vol.24 , pp. 3408-3419
    • Martin, C.1    Williams, A.2    Hernandez-Pando, R.3    Cardona, P.J.4    Gormley, E.5
  • 107
    • 38849102911 scopus 로고    scopus 로고
    • Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain
    • Lee JS, Krause R, Schreiber J, Mollenkopf HJ, Kowall J, et al. (2008) Mutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain. Cell Host Microbe 3: 97-103.
    • (2008) Cell Host Microbe , vol.3 , pp. 97-103
    • Lee, J.S.1    Krause, R.2    Schreiber, J.3    Mollenkopf, H.J.4    Kowall, J.5
  • 108
    • 9144267735 scopus 로고    scopus 로고
    • Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans
    • McShane H, Pathan AA, Sander CR, Keating SM, Gilbert SC, et al. (2004) Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nat Med 10: 1240-1244.
    • (2004) Nat Med , vol.10 , pp. 1240-1244
    • McShane, H.1    Pathan, A.A.2    Sander, C.R.3    Keating, S.M.4    Gilbert, S.C.5
  • 109
    • 74249099784 scopus 로고    scopus 로고
    • Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
    • Scriba TJ, Tameris M, Mansoor N, Smit E, van der Merwe L, et al. (2010) Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells. Eur J Immunol 40: 279-290.
    • (2010) Eur J Immunol , vol.40 , pp. 279-290
    • Scriba, T.J.1    Tameris, M.2    Mansoor, N.3    Smit, E.4    van der Merwe, L.5
  • 110
    • 34547634035 scopus 로고    scopus 로고
    • Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon
    • Radosevic K, Wieland CW, Rodriguez A, Weverling GJ, Mintardjo R, et al. (2007) Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect Immun 75: 4105-4115.
    • (2007) Infect Immun , vol.75 , pp. 4105-4115
    • Radosevic, K.1    Wieland, C.W.2    Rodriguez, A.3    Weverling, G.J.4    Mintardjo, R.5
  • 111
    • 77951826915 scopus 로고    scopus 로고
    • The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults
    • Abel B, Tameris M, Mansoor N, Gelderbloem S, Hughes J, et al. (2010) The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults. Am J Respir Crit Care Med 181: 1407-1417.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 1407-1417
    • Abel, B.1    Tameris, M.2    Mansoor, N.3    Gelderbloem, S.4    Hughes, J.5
  • 112
    • 68349130410 scopus 로고    scopus 로고
    • Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells
    • Hutnick NA, Carnathan DG, Dubey SA, Makedonas G, Cox KS, et al. (2009) Baseline Ad5 serostatus does not predict Ad5 HIV vaccine-induced expansion of adenovirus-specific CD4+ T cells. Nat Med 15: 876-878.
    • (2009) Nat Med , vol.15 , pp. 876-878
    • Hutnick, N.A.1    Carnathan, D.G.2    Dubey, S.A.3    Makedonas, G.4    Cox, K.S.5
  • 113
    • 77949275849 scopus 로고    scopus 로고
    • Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity
    • Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, et al. (2010) Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity. Nat Med 16: 339-345.
    • (2010) Nat Med , vol.16 , pp. 339-345
    • Flatz, L.1    Hegazy, A.N.2    Bergthaler, A.3    Verschoor, A.4    Claus, C.5
  • 114
    • 77950690752 scopus 로고    scopus 로고
    • Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers
    • van Dissel JT, Arend SM, Prins C, Bang P, Tingskov PN, et al. (2010) Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naive human volunteers. Vaccine 28: 3571-3581.
    • (2010) Vaccine , vol.28 , pp. 3571-3581
    • van Dissel, J.T.1    Arend, S.M.2    Prins, C.3    Bang, P.4    Tingskov, P.N.5
  • 115
    • 79951811069 scopus 로고    scopus 로고
    • Ag85B-ESAT-6 adjuvanted with IC31(R) promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection
    • van Dissel JT, Soonawala D, Joosten SA, Prins C, Arend SM, et al. (2011) Ag85B-ESAT-6 adjuvanted with IC31(R) promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection. Vaccine 29: 2100-2109.
    • (2011) Vaccine , vol.29 , pp. 2100-2109
    • van Dissel, J.T.1    Soonawala, D.2    Joosten, S.A.3    Prins, C.4    Arend, S.M.5
  • 116
    • 70349551599 scopus 로고    scopus 로고
    • The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans
    • Von Eschen K, Morrison R, Braun M, Ofori-Anyinam O, De KE, et al. (2009) The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans. Hum Vaccin 5: 475-482.
    • (2009) Hum Vaccin , vol.5 , pp. 475-482
    • von Eschen, K.1    Morrison, R.2    Braun, M.3    Ofori-Anyinam, O.4    De, K.E.5
  • 117
    • 28144437548 scopus 로고    scopus 로고
    • Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6′-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses
    • Davidsen J, Rosenkrands I, Christensen D, Vangala A, Kirby D, et al. (2005) Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6′-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses. Biochim Biophys Acta 1718: 22-31.
    • (2005) Biochim Biophys Acta , vol.1718 , pp. 22-31
    • Davidsen, J.1    Rosenkrands, I.2    Christensen, D.3    Vangala, A.4    Kirby, D.5
  • 118
    • 52349119606 scopus 로고    scopus 로고
    • Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements
    • 10.1371/journal.pone.0003116
    • Agger EM, Rosenkrands I, Hansen J, Brahimi K, Vandahl BS, et al. (2008) Cationic liposomes formulated with synthetic mycobacterial cordfactor (CAF01): a versatile adjuvant for vaccines with different immunological requirements. PLoS ONE 3: e3116 doi:10.1371/journal.pone.0003116.
    • (2008) PLoS ONE , vol.3
    • Agger, E.M.1    Rosenkrands, I.2    Hansen, J.3    Brahimi, K.4    Vandahl, B.S.5
  • 119
    • 73949117849 scopus 로고    scopus 로고
    • Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle
    • Ishikawa E, Ishikawa T, Morita YS, Toyonaga K, Yamada H, et al. (2009) Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J Exp Med 206: 2879-2888.
    • (2009) J Exp Med , vol.206 , pp. 2879-2888
    • Ishikawa, E.1    Ishikawa, T.2    Morita, Y.S.3    Toyonaga, K.4    Yamada, H.5
  • 120
    • 70349759312 scopus 로고    scopus 로고
    • Subcutaneous boosting with heparin binding haemagglutinin increases BCG-induced protection against tuberculosis
    • Rouanet C, Debrie AS, Lecher S, Locht C, (2009) Subcutaneous boosting with heparin binding haemagglutinin increases BCG-induced protection against tuberculosis. Microbes Infect 11: 995-1001.
    • (2009) Microbes Infect , vol.11 , pp. 995-1001
    • Rouanet, C.1    Debrie, A.S.2    Lecher, S.3    Locht, C.4
  • 121
    • 33646199047 scopus 로고    scopus 로고
    • Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis
    • Locht C, Hougardy JM, Rouanet C, Place S, Mascart F, (2006) Heparin-binding hemagglutinin, from an extrapulmonary dissemination factor to a powerful diagnostic and protective antigen against tuberculosis. Tuberculosis (Edinb) 86: 303-309.
    • (2006) Tuberculosis (Edinb) , vol.86 , pp. 303-309
    • Locht, C.1    Hougardy, J.M.2    Rouanet, C.3    Place, S.4    Mascart, F.5
  • 122
    • 0035849873 scopus 로고    scopus 로고
    • The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination
    • Pethe K, Alonso S, Biet F, Delogu G, Brennan MJ, et al. (2001) The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination. Nature 412: 190-194.
    • (2001) Nature , vol.412 , pp. 190-194
    • Pethe, K.1    Alonso, S.2    Biet, F.3    Delogu, G.4    Brennan, M.J.5
  • 123
    • 0043142536 scopus 로고    scopus 로고
    • Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment
    • Schnappinger D, Ehrt S, Voskuil MI, Liu Y, Mangan JA, et al. (2003) Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment. J Exp Med 198: 693-704.
    • (2003) J Exp Med , vol.198 , pp. 693-704
    • Schnappinger, D.1    Ehrt, S.2    Voskuil, M.I.3    Liu, Y.4    Mangan, J.A.5
  • 124
    • 33748194116 scopus 로고    scopus 로고
    • Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis
    • Leyten EM, Lin MY, Franken KL, Friggen AH, Prins C, et al. (2006) Human T-cell responses to 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis. Microbes Infect 8: 2052-2060.
    • (2006) Microbes Infect , vol.8 , pp. 2052-2060
    • Leyten, E.M.1    Lin, M.Y.2    Franken, K.L.3    Friggen, A.H.4    Prins, C.5
  • 125
    • 68149132300 scopus 로고    scopus 로고
    • Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa
    • Black GF, Thiel BA, Ota MO, Parida SK, Adegbola R, et al. (2009) Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa. Clin Vaccine Immunol 16: 1203-1212.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 1203-1212
    • Black, G.F.1    Thiel, B.A.2    Ota, M.O.3    Parida, S.K.4    Adegbola, R.5
  • 126
    • 65949089610 scopus 로고    scopus 로고
    • Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection
    • 10.1371/journal.pone.0005590
    • Schuck SD, Mueller H, Kunitz F, Neher A, Hoffmann H, et al. (2009) Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection. PLoS ONE 4: e5590 doi:10.1371/journal.pone.0005590.
    • (2009) PLoS ONE , vol.4
    • Schuck, S.D.1    Mueller, H.2    Kunitz, F.3    Neher, A.4    Hoffmann, H.5
  • 127
    • 45749106329 scopus 로고    scopus 로고
    • Not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection
    • Lin MY, Ottenhoff TH, (2008) Not to wake a sleeping giant: new insights into host-pathogen interactions identify new targets for vaccination against latent Mycobacterium tuberculosis infection. Biol Chem 389: 497-511.
    • (2008) Biol Chem , vol.389 , pp. 497-511
    • Lin, M.Y.1    Ottenhoff, T.H.2
  • 128
    • 45549098065 scopus 로고    scopus 로고
    • Host-pathogen interactions in latent Mycobacterium tuberculosis infection: identification of new targets for tuberculosis intervention
    • Lin MY, Ottenhoff TH, (2008) Host-pathogen interactions in latent Mycobacterium tuberculosis infection: identification of new targets for tuberculosis intervention. Endocr Metab Immune Disord Drug Targets 8: 15-29.
    • (2008) Endocr Metab Immune Disord Drug Targets , vol.8 , pp. 15-29
    • Lin, M.Y.1    Ottenhoff, T.H.2
  • 129
    • 43049182981 scopus 로고    scopus 로고
    • The enduring hypoxic response of Mycobacterium tuberculosis
    • 10.1371/journal.pone.0001502
    • Rustad TR, Harrell MI, Liao R, Sherman DR, (2008) The enduring hypoxic response of Mycobacterium tuberculosis. PLoS ONE 3: e1502 doi:10.1371/journal.pone.0001502.
    • (2008) PLoS ONE , vol.3
    • Rustad, T.R.1    Harrell, M.I.2    Liao, R.3    Sherman, D.R.4
  • 130
    • 79751497607 scopus 로고    scopus 로고
    • A multistage tuberculosis vaccine that confers efficient protection before and after exposure
    • Aagaard C, Hoang T, Dietrich J, Cardona PJ, Izzo A, et al. (2011) A multistage tuberculosis vaccine that confers efficient protection before and after exposure. Nat Med 17: 189-194.
    • (2011) Nat Med , vol.17 , pp. 189-194
    • Aagaard, C.1    Hoang, T.2    Dietrich, J.3    Cardona, P.J.4    Izzo, A.5
  • 131
    • 78649693679 scopus 로고    scopus 로고
    • Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease
    • Govender L, Abel B, Hughes EJ, Scriba TJ, Kagina BM, et al. (2010) Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease. Vaccine 29: 51-57.
    • (2010) Vaccine , vol.29 , pp. 51-57
    • Govender, L.1    Abel, B.2    Hughes, E.J.3    Scriba, T.J.4    Kagina, B.M.5
  • 132
    • 84855467363 scopus 로고    scopus 로고
    • The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection
    • Lin PL, Dietrich J, Tan E, Abalos RM, Burgos J, et al. (2012) The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection. J Clin Invest 122: 303-314.
    • (2012) J Clin Invest , vol.122 , pp. 303-314
    • Lin, P.L.1    Dietrich, J.2    Tan, E.3    Abalos, R.M.4    Burgos, J.5
  • 133
    • 0028936650 scopus 로고
    • Geographic latitude and the efficacy of bacillus Calmette-Guerin vaccine
    • Wilson ME, Fineberg HV, Colditz GA, (1995) Geographic latitude and the efficacy of bacillus Calmette-Guerin vaccine. Clin Infect Dis 20: 982-991.
    • (1995) Clin Infect Dis , vol.20 , pp. 982-991
    • Wilson, M.E.1    Fineberg, H.V.2    Colditz, G.A.3
  • 134
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu PT, Stenger S, Li H, Wenzel L, Tan BH, et al. (2006) Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 311: 1770-1773.
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3    Wenzel, L.4    Tan, B.H.5
  • 135
    • 80054046948 scopus 로고    scopus 로고
    • Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages
    • Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, et al. (2011) Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages. Sci Transl Med 3: 104ra102.
    • (2011) Sci Transl Med , vol.3
    • Fabri, M.1    Stenger, S.2    Shin, D.M.3    Yuk, J.M.4    Liu, P.T.5
  • 137
    • 33749138039 scopus 로고    scopus 로고
    • IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection
    • Lockhart E, Green AM, Flynn JL, (2006) IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection. J Immunol 177: 4662-4669.
    • (2006) J Immunol , vol.177 , pp. 4662-4669
    • Lockhart, E.1    Green, A.M.2    Flynn, J.L.3
  • 138
    • 84855968010 scopus 로고    scopus 로고
    • Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay
    • Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, et al. (2012) Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay. Genes Immun 13: 71-82.
    • (2012) Genes Immun , vol.13 , pp. 71-82
    • Joosten, S.A.1    Goeman, J.J.2    Sutherland, J.S.3    Opmeer, L.4    de Boer, K.G.5
  • 139
    • 76249095169 scopus 로고    scopus 로고
    • Development of monocytes, macrophages, and dendritic cells
    • Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, et al. (2010) Development of monocytes, macrophages, and dendritic cells. Science 327: 656-661.
    • (2010) Science , vol.327 , pp. 656-661
    • Geissmann, F.1    Manz, M.G.2    Jung, S.3    Sieweke, M.H.4    Merad, M.5
  • 140
    • 33645775989 scopus 로고    scopus 로고
    • Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine
    • Schuurhuis DH, van MN, Ioan-Facsinay A, Jiawan R, Camps M, et al. (2006) Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine. J Immunol 176: 4573-4580.
    • (2006) J Immunol , vol.176 , pp. 4573-4580
    • Schuurhuis, D.H.1    van, M.N.2    Ioan-Facsinay, A.3    Jiawan, R.4    Camps, M.5
  • 142
    • 77954623962 scopus 로고    scopus 로고
    • Airway luminal T cells: a newcomer on the stage of TB vaccination strategies
    • Jeyanathan M, Heriazon A, Xing Z, (2010) Airway luminal T cells: a newcomer on the stage of TB vaccination strategies. Trends Immunol 31: 247-252.
    • (2010) Trends Immunol , vol.31 , pp. 247-252
    • Jeyanathan, M.1    Heriazon, A.2    Xing, Z.3
  • 143
    • 77953070464 scopus 로고    scopus 로고
    • Murine airway luminal antituberculosis memory CD8 T cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment
    • Jeyanathan M, Mu J, McCormick S, Damjanovic D, Small CL, et al. (2010) Murine airway luminal antituberculosis memory CD8 T cells by mucosal immunization are maintained via antigen-driven in situ proliferation, independent of peripheral T cell recruitment. Am J Respir Crit Care Med 181: 862-872.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 862-872
    • Jeyanathan, M.1    Mu, J.2    McCormick, S.3    Damjanovic, D.4    Small, C.L.5
  • 144
    • 81155131557 scopus 로고    scopus 로고
    • Simultaneous immunization against tuberculosis
    • 10.1371/journal.pone.0027477
    • Tchilian EZ, Ronan EO, de Lara C, Lee LN, Franken KL, et al. (2011) Simultaneous immunization against tuberculosis. PLoS ONE 6: e27477 doi:10.1371/journal.pone.0027477.
    • (2011) PLoS ONE , vol.6
    • Tchilian, E.Z.1    Ronan, E.O.2    de Lara, C.3    Lee, L.N.4    Franken, K.L.5
  • 145
    • 79961117289 scopus 로고    scopus 로고
    • CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis
    • Lee LN, Ronan EO, de LC, Franken KL, Ottenhoff TH, et al. (2011) CXCR6 is a marker for protective antigen-specific cells in the lungs after intranasal immunization against Mycobacterium tuberculosis. Infect Immun 79: 3328-3337.
    • (2011) Infect Immun , vol.79 , pp. 3328-3337
    • Lee, L.N.1    Ronan, E.O.2    de, L.C.3    Franken, K.L.4    Ottenhoff, T.H.5


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