Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 8, 2010, Pages 1073-1079

  Kagina, Benjamin M N ^a   Abel, Brian ^a   Scriba, Thomas J ^a   Hughes, Elizabeth J ^a   Keyser, Alana ^a   Soares, Andreia ^a   Gamieldien, Hoyam ^a   Sidibana, Mzwandile ^a   Hatherill, Mark ^a   Gelderbloem, Sebastian ^b   Mahomed, Hassan ^a   Hawkridge, Anthony ^b   Hussey, Gregory ^a   Kaplan, Gilla ^c   Hanekom, Willem A ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b Aeras Global TB Vaccine Foundation   (United States)

^c PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

Mycobacteria immunity; Pediatric settings

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BCG VACCINATION; BLOOD SAMPLING; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL EVALUATION; CORRELATION ANALYSIS; CRYOPRESERVATION; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HUMAN; IMMUNITY; IMMUNOGENICITY; IMMUNOSTIMULATION; INFANT; MAJOR CLINICAL STUDY; NEWBORN; PRIORITY JOURNAL; T LYMPHOCYTE; TUBERCULOSIS;

BCG VACCINE; CASE-CONTROL STUDIES; CD4 LYMPHOCYTE COUNT; CYTOKINES; HUMANS; IMMUNOPHENOTYPING; INFANT, NEWBORN; INTERFERON-GAMMA; PROSPECTIVE STUDIES; SOUTH AFRICA; TUBERCULOSIS;

EID: 77958475885     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201003-0334OC     Document Type: Article

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