-
1
-
-
34948848572
-
Platelet glycoprotein VI-related clinical defects
-
Arthur JF, Dunkley S, Andrews RK (2007b) Platelet glycoprotein VI-related clinical defects. Br J Haematol 139:363-372
-
(2007)
Br J Haematol
, vol.139
, pp. 363-372
-
-
Arthur, J.F.1
Dunkley, S.2
Andrews, R.K.3
-
2
-
-
35649019167
-
Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane
-
Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE (2007a) Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem 282:30434-30441
-
(2007)
J Biol Chem
, vol.282
, pp. 30434-30441
-
-
Arthur, J.F.1
Shen, Y.2
Kahn, M.L.3
Berndt, M.C.4
Andrews, R.K.5
Gardiner, E.E.6
-
3
-
-
0034877518
-
Production and characterization of saratin, an inhibitor of von Willebrand factordependent platelet adhesion to collagen
-
Barnes CS, Krafft B, Frech M, Hofmann UR, Papendieck A, Dahlems U, Gellissen G, Hoylaerts MF (2001) Production and characterization of saratin, an inhibitor of von Willebrand factordependent platelet adhesion to collagen. Semin Thromb Hemost 27:337-348
-
(2001)
Semin Thromb Hemost
, vol.27
, pp. 337-348
-
-
Barnes, C.S.1
Krafft, B.2
Frech, M.3
Hofmann, U.R.4
Papendieck, A.5
Dahlems, U.6
Gellissen, G.7
Hoylaerts, M.F.8
-
4
-
-
78049387105
-
Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases
-
Bender M, Hofmann S, Stegner D, Chalaris A, Bosl M, Braun A, Scheller J, Rose-John S, Nieswandt B (2010) Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases. Blood 116:3347-3355
-
(2010)
Blood
, vol.116
, pp. 3347-3355
-
-
Bender, M.1
Hofmann, S.2
Stegner, D.3
Chalaris, A.4
Bosl, M.5
Braun, A.6
Scheller, J.7
Rose-John, S.8
Nieswandt, B.9
-
5
-
-
34247869049
-
Glycoprotein VI oligomerization in cell lines and platelets
-
Berlanga O, Bori-Sanz T, James JR, Frampton J, Davis SJ, Tomlinson MG, Watson SP (2007) Glycoprotein VI oligomerization in cell lines and platelets. J Thromb Haemost 5:1026-1033
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1026-1033
-
-
Berlanga, O.1
Bori-Sanz, T.2
James, J.R.3
Frampton, J.4
Davis, S.J.5
Tomlinson, M.G.6
Watson, S.P.7
-
6
-
-
67349237179
-
Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS)
-
Bigalke B, Stellos K, Weig HJ, Geisler T, Seizer P, Kremmer E, Potz O, Joos T, May AE, Lindemann S, Gawaz M (2009) Regulation of platelet glycoprotein VI (GPVI) surface expression and of soluble GPVI in patients with atrial fibrillation (AF) and acute coronary syndrome (ACS). Basic Res Cardiol 104:352-357
-
(2009)
Basic Res Cardiol
, vol.104
, pp. 352-357
-
-
Bigalke, B.1
Stellos, K.2
Weig, H.J.3
Geisler, T.4
Seizer, P.5
Kremmer, E.6
Potz, O.7
Joos, T.8
May, A.E.9
Lindemann, S.10
Gawaz, M.11
-
7
-
-
73449086712
-
Expression of platelet glycoprotein VI is associated with transient ischemic attack and stroke
-
Bigalke B, Stellos K, Geisler T, Kremmer E, Seizer P, May AE, Lindemann S, Melms A, Luft A, Gawaz M (2010a) Expression of platelet glycoprotein VI is associated with transient ischemic attack and stroke. Eur J Neurol 17:111-117
-
(2010)
Eur J Neurol
, vol.17
, pp. 111-117
-
-
Bigalke, B.1
Stellos, K.2
Geisler, T.3
Kremmer, E.4
Seizer, P.5
May, A.E.6
Lindemann, S.7
Melms, A.8
Luft, A.9
Gawaz, M.10
-
8
-
-
77950861828
-
Glycoprotein VI as a prognostic biomarker for cardiovascular death in patients with symptomatic coronary artery disease
-
Bigalke B, Stellos K, Geisler T, Lindemann S, May AE, Gawaz M (2010b) Glycoprotein VI as a prognostic biomarker for cardiovascular death in patients with symptomatic coronary artery disease. Clin Res Cardiol 99:227-233
-
(2010)
Clin Res Cardiol
, vol.99
, pp. 227-233
-
-
Bigalke, B.1
Stellos, K.2
Geisler, T.3
Lindemann, S.4
May, A.E.5
Gawaz, M.6
-
9
-
-
33748775203
-
Expression of platelet collagen receptor glycoprotein VI is associated with acute coronary syndrome
-
Bigalke B, Lindemann S, Ehlers R, Seizer P, Daub K, Langer H, Schonberger T, Kremmer E, Siegel-Axel D, May AE, Gawaz M (2006) Expression of platelet collagen receptor glycoprotein VI is associated with acute coronary syndrome. Eur Heart J 27:2165-2169
-
(2006)
Eur Heart J
, vol.27
, pp. 2165-2169
-
-
Bigalke, B.1
Lindemann, S.2
Ehlers, R.3
Seizer, P.4
Daub, K.5
Langer, H.6
Schonberger, T.7
Kremmer, E.8
Siegel-Axel, D.9
May, A.E.10
Gawaz, M.11
-
10
-
-
45849149636
-
Platelet collagen receptor glycoprotein VI as a possible novel indicator for the acute coronary syndrome
-
Bigalke B, Geisler T, Stellos K, Langer H, Daub K, Kremmer E, Seizer P, May AE, Lindemann S, GawazM(2008) Platelet collagen receptor glycoprotein VI as a possible novel indicator for the acute coronary syndrome. Am Heart J 156:193-200
-
(2008)
Am Heart J
, vol.156
, pp. 193-200
-
-
Bigalke, B.1
Geisler, T.2
Stellos, K.3
Langer, H.4
Daub, K.5
Kremmer, E.6
Seizer, P.7
May, A.E.8
Lindemann, S.9
Gawaz, M.10
-
11
-
-
75749139265
-
Platelets amplify inflammation in arthritis via collagen-dependent microparticle production
-
Boilard E, Nigrovic PA, Larabee K, Watts GF, Coblyn JS, Weinblatt ME, Massarotti EM, Remold-O'Donnell E, Farndale RW, Ware J, Lee DM (2010) Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science 327:580-583
-
(2010)
Science
, vol.327
, pp. 580-583
-
-
Boilard, E.1
Nigrovic, P.A.2
Larabee, K.3
Watts, G.F.4
Coblyn, J.S.5
Weinblatt, M.E.6
Massarotti, E.M.7
Remold-O'Donnell, E.8
Farndale, R.W.9
Ware, J.10
Lee, D.M.11
-
12
-
-
77955276576
-
Impact of glycoprotein VI and platelet adhesion on atherosclerosis-A possible role of fibronectin
-
Bultmann A, Li Z, Wagner S, Peluso M, Schonberger T, Weis C, Konrad I, Stellos K, Massberg S, Nieswandt B, Gawaz M, Ungerer M, Munch G (2010) Impact of glycoprotein VI and platelet adhesion on atherosclerosis-a possible role of fibronectin. J Mol Cell Cardiol 49:532-542
-
(2010)
J Mol Cell Cardiol
, vol.49
, pp. 532-542
-
-
Bultmann, A.1
Li, Z.2
Wagner, S.3
Peluso, M.4
Schonberger, T.5
Weis, C.6
Konrad, I.7
Stellos, K.8
Massberg, S.9
Nieswandt, B.10
Gawaz, M.11
Ungerer, M.12
Munch, G.13
-
13
-
-
74549171003
-
Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo
-
Calvo E, Tokumasu F, Mizurini DM, McPhie P, Narum DL, Ribeiro JM, Monteiro RQ, Francischetti IM (2010) Aegyptin displays high-affinity for the von Willebrand factor binding site (RGQOGVMGF) in collagen and inhibits carotid thrombus formation in vivo. FEBS J 277:413-427
-
(2010)
FEBS J
, vol.277
, pp. 413-427
-
-
Calvo, E.1
Tokumasu, F.2
Mizurini, D.M.3
McPhie, P.4
Narum, D.L.5
Ribeiro, J.M.6
Monteiro, R.Q.7
Francischetti, I.M.8
-
14
-
-
0033137302
-
The alpha2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha2beta1 might be a genetic risk factor for the development of stroke in younger patients
-
Carlsson LE, Santoso S, Spitzer C, Kessler C, Greinacher A (1999) The alpha2 gene coding sequence T807/A873 of the platelet collagen receptor integrin alpha2beta1 might be a genetic risk factor for the development of stroke in younger patients. Blood 93:3583-3586
-
(1999)
Blood
, vol.93
, pp. 3583-3586
-
-
Carlsson, L.E.1
Santoso, S.2
Spitzer, C.3
Kessler, C.4
Greinacher, A.5
-
15
-
-
0033013065
-
The hookworm platelet inhibitor: Functional blockade of integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1) inhibits platelet aggregation and adhesion in vitro
-
Chadderdon RC, Cappello M (1999) The hookworm platelet inhibitor: functional blockade of integrins GPIIb/IIIa (alphaIIbbeta3) and GPIa/IIa (alpha2beta1) inhibits platelet aggregation and adhesion in vitro. J Infect Dis 179:1235-1241
-
(1999)
J Infect Dis
, vol.179
, pp. 1235-1241
-
-
Chadderdon, R.C.1
Cappello, M.2
-
16
-
-
34548079309
-
Cardiovascular effects of Danshen
-
Cheng TO (2007) Cardiovascular effects of Danshen. Int J Cardiol 121:9-22
-
(2007)
Int J Cardiol
, vol.121
, pp. 9-22
-
-
Cheng, T.O.1
-
17
-
-
0037144399
-
Cloning, characterization, and functional studies of a 47-kDa platelet receptor for type III collagen
-
Chiang TM, Cole F, Woo-Rasberry V (2002) Cloning, characterization, and functional studies of a 47-kDa platelet receptor for type III collagen. J Biol Chem 277:34896-34901
-
(2002)
J Biol Chem
, vol.277
, pp. 34896-34901
-
-
Chiang, T.M.1
Cole, F.2
Woo-Rasberry, V.3
-
18
-
-
0030727354
-
A synthetic peptide derived from the sequence of a type i collagen receptor inhibits type i collagen-mediated platelet aggregation
-
Chiang TM, Kang AH (1997) A synthetic peptide derived from the sequence of a type I collagen receptor inhibits type I collagen-mediated platelet aggregation. J Clin Invest 100:2079-2084
-
(1997)
J Clin Invest
, vol.100
, pp. 2079-2084
-
-
Chiang, T.M.1
Kang, A.H.2
-
19
-
-
0030742053
-
Cloning, characterization, and functional studies of a nonintegrin platelet receptor for type i collagen
-
Chiang TM, Rinaldy A, Kang AH (1997) Cloning, characterization, and functional studies of a nonintegrin platelet receptor for type I collagen. J Clin Invest 100:514-521
-
(1997)
J Clin Invest
, vol.100
, pp. 514-521
-
-
Chiang, T.M.1
Rinaldy, A.2
Kang, A.H.3
-
20
-
-
0027316934
-
Collagen-platelet interaction: Separate receptor sites for types i and III collagen
-
Chiang TM, Seyer JM, Kang AH (1993) Collagen-platelet interaction: separate receptor sites for types I and III collagen. Thromb Res 71:443-456
-
(1993)
Thromb Res
, vol.71
, pp. 443-456
-
-
Chiang, T.M.1
Seyer, J.M.2
Kang, A.H.3
-
21
-
-
0032828086
-
The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors
-
Clemetson JM, Polgar J, Magnenat E, Wells TN, Clemetson KJ (1999) The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors. J Biol Chem 274:29019-29024
-
(1999)
J Biol Chem
, vol.274
, pp. 29019-29024
-
-
Clemetson, J.M.1
Polgar, J.2
Magnenat, E.3
Wells, T.N.4
Clemetson, K.J.5
-
22
-
-
0024321318
-
Collagen-platelet interactions: Evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins
-
Coller BS, Beer JH, Scudder LE, Steinberg MH (1989) Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins. Blood 74:182-192
-
(1989)
Blood
, vol.74
, pp. 182-192
-
-
Coller, B.S.1
Beer, J.H.2
Scudder, L.E.3
Steinberg, M.H.4
-
23
-
-
0026733452
-
An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization
-
Connolly TM, Jacobs JW, Condra C (1992) An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization. J Biol Chem 267:6893-6898
-
(1992)
J Biol Chem
, vol.267
, pp. 6893-6898
-
-
Connolly, T.M.1
Jacobs, J.W.2
Condra, C.3
-
24
-
-
0035949498
-
Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction
-
Croft SA, Samani NJ, Hampton KK, Steeds RP, Channer KS, Daly ME (2001) Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction. Circulation 104:1459-1463
-
(2001)
Circulation
, vol.104
, pp. 1459-1463
-
-
Croft, S.A.1
Samani, N.J.2
Hampton, K.K.3
Steeds, R.P.4
Channer, K.S.5
Daly, M.E.6
-
25
-
-
0035491108
-
Saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion, decreases platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model
-
Cruz CP, Eidt J, Drouilhet J, Brown AT, Wang Y, Barnes CS, Moursi MM (2001) Saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion, decreases platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg 34:724-729
-
(2001)
J Vasc Surg
, vol.34
, pp. 724-729
-
-
Cruz, C.P.1
Eidt, J.2
Drouilhet, J.3
Brown, A.T.4
Wang, Y.5
Barnes, C.S.6
Moursi, M.M.7
-
26
-
-
0028212628
-
Collagen induces normal signal transduction in platelets deficient in CD36 (platelet glycoprotein IV)
-
Daniel JL, Dangelmaier C, Strouse R, Smith JB (1994) Collagen induces normal signal transduction in platelets deficient in CD36 (platelet glycoprotein IV). Thromb Haemost 71:353-356
-
(1994)
Thromb Haemost
, vol.71
, pp. 353-356
-
-
Daniel, J.L.1
Dangelmaier, C.2
Strouse, R.3
Smith, J.B.4
-
27
-
-
0025042513
-
Lack of platelet response to collagen associated with an autoantibody against glycoprotein Ia: A novel cause of acquired qualitative platelet dysfunction
-
Deckmyn H, Chew SL, Vermylen J (1990) Lack of platelet response to collagen associated with an autoantibody against glycoprotein Ia: a novel cause of acquired qualitative platelet dysfunction. Thromb Haemost 64:74-79
-
(1990)
Thromb Haemost
, vol.64
, pp. 74-79
-
-
Deckmyn, H.1
Chew, S.L.2
Vermylen, J.3
-
28
-
-
0028931844
-
Calin from Hirudo medicinalis, an inhibitor of platelet adhesion to collagen, prevents platelet-rich thrombosis in hamsters
-
Deckmyn H, Stassen JM, Vreys I, Van Houtte E, Sawyer RT, Vermylen J (1995) Calin from Hirudo medicinalis, an inhibitor of platelet adhesion to collagen, prevents platelet-rich thrombosis in hamsters. Blood 85:712-719
-
(1995)
Blood
, vol.85
, pp. 712-719
-
-
Deckmyn, H.1
Stassen, J.M.2
Vreys, I.3
Van Houtte, E.4
Sawyer, R.T.5
Vermylen, J.6
-
29
-
-
0032865278
-
The collagen-binding leech products rLAPP and calin prevent both von Willebrand factor and alpha2beta1(GPIa/IIa)-I-domain binding to collagen in a different manner
-
Depraetere H, Kerekes A, Deckmyn H (1999) The collagen-binding leech products rLAPP and calin prevent both von Willebrand factor and alpha2beta1(GPIa/IIa)-I-domain binding to collagen in a different manner. Thromb Haemost 82:1160-1163
-
(1999)
Thromb Haemost
, vol.82
, pp. 1160-1163
-
-
Depraetere, H.1
Kerekes, A.2
Deckmyn, H.3
-
30
-
-
0027255014
-
Platelets lacking functional CD36 (glycoprotein IV) show reduced adhesion to collagen in flowing whole blood
-
Diaz-Ricart M, Tandon NN, Carretero M, Ordinas A, Bastida E, Jamieson GA (1993) Platelets lacking functional CD36 (glycoprotein IV) show reduced adhesion to collagen in flowing whole blood. Blood 82:491-496
-
(1993)
Blood
, vol.82
, pp. 491-496
-
-
Diaz-Ricart, M.1
Tandon, N.N.2
Carretero, M.3
Ordinas, A.4
Bastida, E.5
Jamieson, G.A.6
-
31
-
-
84855836837
-
Platelet type III collagen binding protein (TIIICBP) presents high biochemical and functional similarities with kindlin-3
-
Djaafri I, Maurice P, Labas V, Vinh J, Lemesle M, Arbeille B, Legrand C, Mourah S, Fauvel- Lafeve F (2011) Platelet type III collagen binding protein (TIIICBP) presents high biochemical and functional similarities with kindlin-3. Biochimie 94(2):416-426
-
(2011)
Biochimie
, vol.94
, Issue.2
, pp. 416-426
-
-
Djaafri, I.1
Maurice, P.2
Labas, V.3
Vinh, J.4
Lemesle, M.5
Arbeille, B.6
Legrand, C.7
Mourah, S.8
Fauvel- Lafeve, F.9
-
32
-
-
37749025513
-
A recombinant protein and a chemically synthesized peptide containing the active peptides of the platelet collagen receptors inhibit ferric chloride-induced thrombosis in a rat model
-
Du H, Zawaski JA, Gaber MW, Chiang TM (2007) A recombinant protein and a chemically synthesized peptide containing the active peptides of the platelet collagen receptors inhibit ferric chloride-induced thrombosis in a rat model. Thromb Res 121:419-426
-
(2007)
Thromb Res
, vol.121
, pp. 419-426
-
-
Du, H.1
Zawaski, J.A.2
Gaber, M.W.3
Chiang, T.M.4
-
33
-
-
33646587380
-
Glycoprotein VIdependent and -independent pathways of thrombus formation in vivo
-
Dubois C, Panicot-Dubois L, Merrill-Skoloff G, Furie B, Furie BC (2006) Glycoprotein VIdependent and -independent pathways of thrombus formation in vivo. Blood 107:3902-3906
-
(2006)
Blood
, vol.107
, pp. 3902-3906
-
-
Dubois, C.1
Panicot-Dubois, L.2
Merrill-Skoloff, G.3
Furie, B.4
Furie, B.C.5
-
34
-
-
70349263950
-
Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations
-
Dumont B, Lasne D, Rothschild C, Bouabdelli M, Ollivier V, Oudin C, Ajzenberg N, Grandchamp B, Jandrot-Perrus M (2009) Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations. Blood 114:1900-1903
-
(2009)
Blood
, vol.114
, pp. 1900-1903
-
-
Dumont, B.1
Lasne, D.2
Rothschild, C.3
Bouabdelli, M.4
Ollivier, V.5
Oudin, C.6
Ajzenberg, N.7
Grandchamp, B.8
Jandrot-Perrus, M.9
-
35
-
-
0035853796
-
Alpha 2beta 1 integrin is not recognized by rhodocytin but is the specific, high affinity target of rhodocetin, an RGDindependent disintegrin and potent inhibitor of cell adhesion to collagen
-
Eble JA, Beermann B, Hinz HJ, Schmidt-Hederich A (2001) alpha 2beta 1 integrin is not recognized by rhodocytin but is the specific, high affinity target of rhodocetin, an RGDindependent disintegrin and potent inhibitor of cell adhesion to collagen. J Biol Chem 276:12274-12284
-
(2001)
J Biol Chem
, vol.276
, pp. 12274-12284
-
-
Eble, J.A.1
Beermann, B.2
Hinz, H.J.3
Schmidt-Hederich, A.4
-
36
-
-
0344309120
-
The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site
-
Eble JA, Tuckwell DS (2003) The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site. Biochem J 376:77-85
-
(2003)
Biochem J
, vol.376
, pp. 77-85
-
-
Eble, J.A.1
Tuckwell, D.S.2
-
37
-
-
0038036093
-
Vipera lebetina venom contains two disintegrins inhibiting laminin-binding beta1 integrins
-
Eble JA, Bruckner P, Mayer U (2003) Vipera lebetina venom contains two disintegrins inhibiting laminin-binding beta1 integrins. J Biol Chem 278:26488-26496
-
(2003)
J Biol Chem
, vol.278
, pp. 26488-26496
-
-
Eble, J.A.1
Bruckner, P.2
Mayer, U.3
-
38
-
-
73849131692
-
Platelets contribute to postnatal occlusion of the ductus arteriosus
-
Echtler K, Stark K, Lorenz M, Kerstan S, Walch A, Jennen L, Rudelius M, Seidl S, Kremmer E, Emambokus NR, von BruehlML, Frampton J, Isermann B, Genzel-Boroviczeny O, Schreiber C, Mehilli J, Kastrati A, Schwaiger M, Shivdasani RA, Massberg S (2010) Platelets contribute to postnatal occlusion of the ductus arteriosus. Nat Med 16:75-82
-
(2010)
Nat Med
, vol.16
, pp. 75-82
-
-
Echtler, K.1
Stark, K.2
Lorenz, M.3
Kerstan, S.4
Walch, A.5
Jennen, L.6
Rudelius, M.7
Seidl, S.8
Kremmer, E.9
Emambokus, N.R.10
Von Bruehlml Frampton, J.11
Isermann, B.12
Genzel-Boroviczeny, O.13
Schreiber, C.14
Mehilli, J.15
Kastrati, A.16
Schwaiger, M.17
Shivdasani, R.A.18
Massberg, S.19
-
39
-
-
0347123535
-
Structure of the integrin alpha2beta1- binding collagen peptide
-
Emsley J, Knight CG, Farndale RW, Barnes MJ (2004) Structure of the integrin alpha2beta1- binding collagen peptide. J Mol Biol 335:1019-1028
-
(2004)
J Mol Biol
, vol.335
, pp. 1019-1028
-
-
Emsley, J.1
Knight, C.G.2
Farndale, R.W.3
Barnes, M.J.4
-
40
-
-
0034737296
-
Structural basis of collagen recognition by integrin alpha2beta1
-
Emsley J, Knight CG, Farndale RW, Barnes MJ, Liddington RC (2000) Structural basis of collagen recognition by integrin alpha2beta1. Cell 101:47-56
-
(2000)
Cell
, vol.101
, pp. 47-56
-
-
Emsley, J.1
Knight, C.G.2
Farndale, R.W.3
Barnes, M.J.4
Liddington, R.C.5
-
42
-
-
0033544849
-
Functional analysis of a recombinant glycoprotein Ia/IIa (Integrin alpha(2)beta(1)) i domain that inhibits platelet adhesion to collagen and endothelial matrix under flow conditions
-
Estavillo D, Ritchie A, Diacovo TG, Cruz MA (1999) Functional analysis of a recombinant glycoprotein Ia/IIa (Integrin alpha(2)beta(1)) I domain that inhibits platelet adhesion to collagen and endothelial matrix under flow conditions. J Biol Chem 274:35921-35926
-
(1999)
J Biol Chem
, vol.274
, pp. 35921-35926
-
-
Estavillo, D.1
Ritchie, A.2
Diacovo, T.G.3
Cruz, M.A.4
-
43
-
-
0036192238
-
Influence of platelet collagen receptor polymorphisms on risk for arterial thrombosis
-
Furihata K, Nugent DJ, Kunicki TJ (2002) Influence of Platelet Collagen Receptor Polymorphisms on Risk for Arterial Thrombosis. Arch Pathol Lab Med 126:305-309
-
(2002)
Arch Pathol Lab Med
, vol.126
, pp. 305-309
-
-
Furihata, K.1
Nugent, D.J.2
Kunicki, T.J.3
-
44
-
-
48449085875
-
Structure of the leech protein saratin and characterization of its binding to collagen
-
Gronwald W, Bomke J, Maurer T, Domogalla B, Huber F, Schumann F, Kremer W, Fink F, Rysiok T, Frech M, Kalbitzer HR (2008) Structure of the leech protein saratin and characterization of its binding to collagen. J Mol Biol 381:913-927
-
(2008)
J Mol Biol
, vol.381
, pp. 913-927
-
-
Gronwald, W.1
Bomke, J.2
Maurer, T.3
Domogalla, B.4
Huber, F.5
Schumann, F.6
Kremer, W.7
Fink, F.8
Rysiok, T.9
Frech, M.10
Kalbitzer, H.R.11
-
45
-
-
34247372574
-
EXP3179 inhibits collagendependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: Potential impact on atherothrombosis
-
Grothusen C, Umbreen S, Konrad I, Stellos K, Schulz C, Schmidt B, Kremmer E, Teebken O, Massberg S, Luchtefeld M, Schieffer B, Gawaz M (2007) EXP3179 inhibits collagendependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: potential impact on atherothrombosis. Arterioscler Thromb Vasc Biol 27:1184-1190
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1184-1190
-
-
Grothusen, C.1
Umbreen, S.2
Konrad, I.3
Stellos, K.4
Schulz, C.5
Schmidt, B.6
Kremmer, E.7
Teebken, O.8
Massberg, S.9
Luchtefeld, M.10
Schieffer, B.11
Gawaz, M.12
-
46
-
-
13544270777
-
Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice
-
Gruner S, Prostredna M, Koch M, Miura Y, Schulte V, Jung SM, Moroi M, Nieswandt B (2005) Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice. Blood 105:1492-1499
-
(2005)
Blood
, vol.105
, pp. 1492-1499
-
-
Gruner, S.1
Prostredna, M.2
Koch, M.3
Miura, Y.4
Schulte, V.5
Jung, S.M.6
Moroi, M.7
Nieswandt, B.8
-
47
-
-
0345257356
-
Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo
-
Gruner S, Prostredna M, Schulte V, Krieg T, Eckes B, Brakebusch C, Nieswandt B (2003) Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo. Blood 102:4021-4027
-
(2003)
Blood
, vol.102
, pp. 4021-4027
-
-
Gruner, S.1
Prostredna, M.2
Schulte, V.3
Krieg, T.4
Eckes, B.5
Brakebusch, C.6
Nieswandt, B.7
-
48
-
-
38349123913
-
Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion
-
Han JY, Fan JY, Horie Y, Miura S, Cui DH, Ishii H, Hibi T, Tsuneki H, Kimura I (2008) Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion. Pharmacol Ther 117:280-295
-
(2008)
Pharmacol Ther
, vol.117
, pp. 280-295
-
-
Han, J.Y.1
Fan, J.Y.2
Horie, Y.3
Miura, S.4
Cui, D.H.5
Ishii, H.6
Hibi, T.7
Tsuneki, H.8
Kimura, I.9
-
49
-
-
0028957133
-
Platelet unresponsiveness to collagen: Involvement of glycoprotein Ia- IIa (alpha 2 beta 1 integrin) deficiency associated with a myeloproliferative disorder
-
Handa M, Watanabe K, Kawai Y, Kamata T, Koyama T, Nagai H, Ikeda Y (1995) Platelet unresponsiveness to collagen: involvement of glycoprotein Ia- IIa (alpha 2 beta 1 integrin) deficiency associated with a myeloproliferative disorder. Thromb Haemost 73:521-528
-
(1995)
Thromb Haemost
, vol.73
, pp. 521-528
-
-
Handa, M.1
Watanabe, K.2
Kawai, Y.3
Kamata, T.4
Koyama, T.5
Nagai, H.6
Ikeda, Y.7
-
50
-
-
0028928893
-
Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions
-
Harsfalvi J, Stassen JM, Hoylaerts MF, Van Houtte E, Sawyer RT, Vermylen J, Deckmyn H (1995) Calin from Hirudo medicinalis, an inhibitor of von Willebrand factor binding to collagen under static and flow conditions. Blood 85:705-711
-
(1995)
Blood
, vol.85
, pp. 705-711
-
-
Harsfalvi, J.1
Stassen, J.M.2
Hoylaerts, M.F.3
Van Houtte, E.4
Sawyer, R.T.5
Vermylen, J.6
Deckmyn, H.7
-
51
-
-
0033135750
-
Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines
-
Hebert C, Norris K, Della CR, Reynolds M, Ordonez J, Sauk JJ (1999) Cell surface colligin/Hsp47 associates with tetraspanin protein CD9 in epidermoid carcinoma cell lines. J Cell Biochem 73:248-258
-
(1999)
J Cell Biochem
, vol.73
, pp. 248-258
-
-
Hebert, C.1
Norris, K.2
Della Reynolds, C.R.M.3
Ordonez, J.4
Sauk, J.J.5
-
52
-
-
0242494878
-
The contributions of the alpha (2)beta (1) integrin to vascular thrombosis in vivo
-
He L, Pappan LK, Grenache DG, Li ZZ, Tollefsen DM, Santoro SA, Zutter MM (2003) The contributions of the alpha(2)beta(1) integrin to vascular thrombosis in vivo. Blood 102:3652-3657
-
(2003)
Blood
, vol.102
, pp. 3652-3657
-
-
He, L.1
Pappan, L.K.2
Grenache, D.G.3
Li, Z.Z.4
Tollefsen, D.M.5
Santoro, S.A.6
Zutter, M.M.7
-
53
-
-
73049103413
-
Arterial thrombosis: Relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization
-
Hechler B, Nonne C, Eckly A, Magnenat S, Rinckel JY, Denis CV, Freund M, Cazenave JP, Lanza F, Gachet C (2010) Arterial thrombosis: relevance of a model with two levels of severity assessed by histologic, ultrastructural and functional characterization. J Thromb Haemost 8:173-184
-
(2010)
J Thromb Haemost
, vol.8
, pp. 173-184
-
-
Hechler, B.1
Nonne, C.2
Eckly, A.3
Magnenat, S.4
Rinckel, J.Y.5
Denis, C.V.6
Freund, M.7
Cazenave, J.P.8
Lanza, F.9
Gachet, C.10
-
54
-
-
67949091190
-
A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder
-
Hermans C, Wittevrongel C, Thys C, Smethurst PA, Van GC, Freson K (2009) A compound heterozygous mutation in glycoprotein VI in a patient with a bleeding disorder. J Thromb Haemost 7:1356-1363
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1356-1363
-
-
Hermans, C.1
Wittevrongel, C.2
Thys, C.3
Smethurst, P.A.4
Van Gc Freson, K.5
-
55
-
-
67749124481
-
Structural insights into the interactions between platelet receptors and fibrillar collagen
-
Herr AB, Farndale RW (2009) Structural insights into the interactions between platelet receptors and fibrillar collagen. J Biol Chem 284:19781-19785
-
(2009)
J Biol Chem
, vol.284
, pp. 19781-19785
-
-
Herr, A.B.1
Farndale, R.W.2
-
56
-
-
0038640337
-
Pathophysiology of human genetic CD36 deficiency
-
Hirano K, Kuwasako T, Nakagawa-Toyama Y, Janabi M, Yamashita S, Matsuzawa Y (2003) Pathophysiology of human genetic CD36 deficiency. Trends Cardiovasc Med 13:136-141
-
(2003)
Trends Cardiovasc Med
, vol.13
, pp. 136-141
-
-
Hirano, K.1
Kuwasako, T.2
Nakagawa-Toyama, Y.3
Janabi, M.4
Yamashita, S.5
Matsuzawa, Y.6
-
57
-
-
0037192771
-
Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen
-
Holtkotter O, Nieswandt B, Smyth N, Muller W, Hafner M, Schulte V, Krieg T, Eckes B (2002) Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem 277:10789-10794
-
(2002)
J Biol Chem
, vol.277
, pp. 10789-10794
-
-
Holtkotter, O.1
Nieswandt, B.2
Smyth, N.3
Muller, W.4
Hafner, M.5
Schulte, V.6
Krieg, T.7
Eckes, B.8
-
58
-
-
33746658013
-
Structural basis for platelet collagen responses by the immunetype receptor glycoprotein VI
-
Horii K, Kahn ML, Herr AB (2006) Structural basis for platelet collagen responses by the immunetype receptor glycoprotein VI. Blood 108:936-942
-
(2006)
Blood
, vol.108
, pp. 936-942
-
-
Horii, K.1
Kahn, M.L.2
Herr, A.B.3
-
59
-
-
0005201628
-
Aggregation of rabbit blood platelets produced in vitro by saline extract of tendons
-
Hovig T (1963) Aggregation of rabbit blood platelets produced in vitro by saline extract of tendons. Thromb Diath Haemorrh 143:248-263
-
(1963)
Thromb Diath Haemorrh
, vol.143
, pp. 248-263
-
-
Hovig, T.1
-
60
-
-
49849103616
-
A snake venom metalloproteinase, kistomin, cleaves platelet glycoprotein VI and impairs platelet functions
-
Hsu CC, Wu WB, Huang TF (2008) A snake venom metalloproteinase, kistomin, cleaves platelet glycoprotein VI and impairs platelet functions. J Thromb Haemost 6:1578-1585
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1578-1585
-
-
Hsu, C.C.1
Wu, W.B.2
Huang, T.F.3
-
61
-
-
32644435352
-
Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI
-
Inoue O, Suzuki-Inoue K, McCarty OJ, Moroi M, Ruggeri ZM, Kunicki TJ, Ozaki Y, Watson SP (2006) Laminin stimulates spreading of platelets through integrin alpha6beta1-dependent activation of GPVI. Blood 107:1405-1412
-
(2006)
Blood
, vol.107
, pp. 1405-1412
-
-
Inoue, O.1
Suzuki-Inoue, K.2
McCarty, O.J.3
Moroi, M.4
Ruggeri, Z.M.5
Kunicki, T.J.6
Ozaki, Y.7
Watson, S.P.8
-
62
-
-
0034284219
-
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: A platelet-specific collagen receptor from the immunoglobulin superfamily
-
Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL (2000) Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily. Blood 96:1798-1807
-
(2000)
Blood
, vol.96
, pp. 1798-1807
-
-
Jandrot-Perrus, M.1
Busfield, S.2
Lagrue, A.H.3
Xiong, X.4
Debili, N.5
Chickering, T.6
Le Couedic, J.P.7
Goodearl, A.8
Dussault, B.9
Fraser, C.10
Vainchenker, W.11
Villeval, J.L.12
-
63
-
-
46749100659
-
Identification of a major GpVI-binding locus in human type III collagen
-
Jarvis GE, Raynal N, Langford JP, Onley DJ, Andrews A, Smethurst PA, Farndale RW (2008) Identification of a major GpVI-binding locus in human type III collagen. Blood 111:4986-4996
-
(2008)
Blood
, vol.111
, pp. 4986-4996
-
-
Jarvis, G.E.1
Raynal, N.2
Langford, J.P.3
Onley, D.J.4
Andrews, A.5
Smethurst, P.A.6
Farndale, R.W.7
-
64
-
-
0038819123
-
The lowfrequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression
-
Joutsi-Korhonen L, Smethurst PA, Rankin A, Gray E, Ijsseldijk M, Onley CM, Watkins NA, Williamson LM, Goodall AH, de Groot PG, Famdale RW, Ouwehand WH (2003) The lowfrequency allele of the platelet collagen signaling receptor glycoprotein VI is associated with reduced functional responses and expression. Blood 101:4372-4379
-
(2003)
Blood
, vol.101
, pp. 4372-4379
-
-
Joutsi-Korhonen, L.1
Smethurst, P.A.2
Rankin, A.3
Gray, E.4
Ijsseldijk, M.5
Onley, C.M.6
Watkins, N.A.7
Williamson, L.M.8
Goodall, A.H.9
De Groot, P.G.10
Famdale, R.W.11
Ouwehand, W.H.12
-
65
-
-
0034678129
-
Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha (2)beta (1)
-
Jung SM, Moroi M (2000) Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin alpha(2)beta(1). J Biol Chem 275:8016-8026
-
(2000)
J Biol Chem
, vol.275
, pp. 8016-8026
-
-
Jung, S.M.1
Moroi, M.2
-
66
-
-
67949089731
-
Glycoprotein (GP) VI dimer as a major collagen-binding site of native platelets: Direct evidence obtained with dimeric GPVI-specific Fabs
-
Jung SM, Tsuji K, MoroiM(2009) Glycoprotein (GP) VI dimer as a major collagen-binding site of native platelets: direct evidence obtained with dimeric GPVI-specific Fabs. J Thromb Haemost 7:1347-1355
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1347-1355
-
-
Jung, S.M.1
Tsuji, K.2
Moroi, M.3
-
67
-
-
67049125717
-
A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets
-
Kaiser WJ, Holbrook LM, Tucker KL, Stanley RG, Gibbins JM (2009) A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets. J Proteome Res 8:2903-2914
-
(2009)
J Proteome Res
, vol.8
, pp. 2903-2914
-
-
Kaiser, W.J.1
Holbrook, L.M.2
Tucker, K.L.3
Stanley, R.G.4
Gibbins, J.M.5
-
68
-
-
0028225987
-
Identification of putative ligand binding sites within i domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29)
-
Kamata T, Puzon W, Takada Y (1994) Identification of putative ligand binding sites within I domain of integrin alpha 2 beta 1 (VLA-2, CD49b/CD29). J Biol Chem 269:9659-9663
-
(1994)
J Biol Chem
, vol.269
, pp. 9659-9663
-
-
Kamata, T.1
Puzon, W.2
Takada, Y.3
-
69
-
-
0031283167
-
Proteolytic cleavage of the beta1 subunit of platelet alpha2beta1 integrin by the metalloproteinase jararhagin compromises collagen-stimulated phosphorylation of pp72
-
Kamiguti AS, Markland FS, Zhou Q, Laing GD, Theakston RD, Zuzel M (1997) Proteolytic cleavage of the beta1 subunit of platelet alpha2beta1 integrin by the metalloproteinase jararhagin compromises collagen-stimulated phosphorylation of pp72. J Biol Chem 272:32599-32605
-
(1997)
J Biol Chem
, vol.272
, pp. 32599-32605
-
-
Kamiguti, A.S.1
Markland, F.S.2
Zhou, Q.3
Laing, G.D.4
Theakston, R.D.5
Zuzel, M.6
-
70
-
-
34250155581
-
Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function
-
Kapyla J, Pentikainen OT, Nyronen T, Nissinen L, Lassander S, Jokinen J, Lahti M, Marjamaki A, Johnson MS, Heino J (2007) Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function. J Med Chem 50:2742-2746
-
(2007)
J Med Chem
, vol.50
, pp. 2742-2746
-
-
Kapyla, J.1
Pentikainen, O.T.2
Nyronen, T.3
Nissinen, L.4
Lassander, S.5
Jokinen, J.6
Lahti, M.7
Marjamaki, A.8
Johnson, M.S.9
Heino, J.10
-
71
-
-
0042442163
-
The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion
-
Kato K, Kanaji T, Russell S, Kunicki TJ, Furihata K, Kanaji S, Marchese P, Reininger A, Ruggeri ZM, Ware J (2003) The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion. Blood 102:1701-1707
-
(2003)
Blood
, vol.102
, pp. 1701-1707
-
-
Kato, K.1
Kanaji, T.2
Russell, S.3
Kunicki, T.J.4
Furihata, K.5
Kanaji, S.6
Marchese, P.7
Reininger, A.8
Ruggeri, Z.M.9
Ware, J.10
-
72
-
-
0026705756
-
An inhibitor of collagenstimulated platelet activation from the salivary glands of the Haementeria officinalis leech. II. Cloning of the cDNA and expression
-
Keller PM, Schultz LD, Condra C, Karczewski J, Connolly TM (1992) An inhibitor of collagenstimulated platelet activation from the salivary glands of the Haementeria officinalis leech. II. Cloning of the cDNA and expression. J Biol Chem 267:6899-6904
-
(1992)
J Biol Chem
, vol.267
, pp. 6899-6904
-
-
Keller, P.M.1
Schultz, L.D.2
Condra, C.3
Karczewski, J.4
Connolly, T.M.5
-
73
-
-
0025159429
-
Alpha 2 beta 1 integrins from different cell types show different binding specificities
-
Kirchhofer D, Languino LR, Ruoslahti E, Pierschbacher MD (1990) Alpha 2 beta 1 integrins from different cell types show different binding specificities. J Biol Chem 265:615-618
-
(1990)
J Biol Chem
, vol.265
, pp. 615-618
-
-
Kirchhofer, D.1
Languino, L.R.2
Ruoslahti, E.3
Pierschbacher, M.D.4
-
74
-
-
34247643257
-
Targeting platelets in acute experimental stroke: Impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding
-
Kleinschnitz C, Pozgajova M, Pham M, Bendszus M, Nieswandt B, Stoll G (2007) Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding. Circulation 115:2323-2330
-
(2007)
Circulation
, vol.115
, pp. 2323-2330
-
-
Kleinschnitz, C.1
Pozgajova, M.2
Pham, M.3
Bendszus, M.4
Nieswandt, B.5
Stoll, G.6
-
75
-
-
0037177026
-
Platelets activated by collagen through immunoreceptor tyrosine-based activation motif play pivotal role in initiation and generation of neointimal hyperplasia after vascular injury
-
Konishi H, Katoh Y, Takaya N, Kashiwakura Y, Itoh S, Ra C, Daida H (2002) Platelets activated by collagen through immunoreceptor tyrosine-based activation motif play pivotal role in initiation and generation of neointimal hyperplasia after vascular injury. Circulation 105:912-916
-
(2002)
Circulation
, vol.105
, pp. 912-916
-
-
Konishi, H.1
Katoh, Y.2
Takaya, N.3
Kashiwakura, Y.4
Itoh, S.5
Ra, C.6
Daida, H.7
-
76
-
-
33747175371
-
Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis
-
Konstantinides S, Ware J, Marchese P, mus-Jacobs F, Loskutoff DJ, Ruggeri ZM (2006) Distinct antithrombotic consequences of platelet glycoprotein Ibalpha and VI deficiency in a mouse model of arterial thrombosis. J Thromb Haemost 4:2014-2021
-
(2006)
J Thromb Haemost
, vol.4
, pp. 2014-2021
-
-
Konstantinides, S.1
Ware, J.2
Marchese, P.3
Mus-Jacobs, F.4
Loskutoff, D.J.5
Ruggeri, Z.M.6
-
77
-
-
0032173427
-
Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density
-
Kritzik M, Savage B, Nugent DJ, Santoso S, Ruggeri ZM, Kunicki TJ (1998) Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density. Blood 92:2382-2388
-
(1998)
Blood
, vol.92
, pp. 2382-2388
-
-
Kritzik, M.1
Savage, B.2
Nugent, D.J.3
Santoso, S.4
Ruggeri, Z.M.5
Kunicki, T.J.6
-
78
-
-
36048964007
-
Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: Contribution of thromboxane A2
-
Kuijpers MJ, Pozgajova M, Cosemans JM, Munnix IC, Eckes B, Nieswandt B, Heemskerk JW (2007) Role of murine integrin alpha2beta1 in thrombus stabilization and embolization: contribution of thromboxane A2. Thromb Haemost 98:1072-1080
-
(2007)
Thromb Haemost
, vol.98
, pp. 1072-1080
-
-
Kuijpers, M.J.1
Pozgajova, M.2
Cosemans, J.M.3
Munnix, I.C.4
Eckes, B.5
Nieswandt, B.6
Heemskerk, J.W.7
-
79
-
-
79956148120
-
The metalloprotease, NN-PF3 from Naja naja venom inhibits platelet aggregation primarily by affecting alpha2beta1 integrin
-
Kumar MS, Girish KS, Vishwanath BS, Kemparaju K (2011) The metalloprotease, NN-PF3 from Naja naja venom inhibits platelet aggregation primarily by affecting alpha2beta1 integrin. Ann Hematol 90:569-577
-
(2011)
Ann Hematol
, vol.90
, pp. 569-577
-
-
Kumar, M.S.1
Girish, K.S.2
Vishwanath, B.S.3
Kemparaju, K.4
-
80
-
-
0027431790
-
Variability of integrin alpha 2 beta 1 activity on human platelets
-
Kunicki TJ, Orchekowski R, Annis D, Honda Y (1993) Variability of integrin alpha 2 beta 1 activity on human platelets. Blood 82:2693-2703
-
(1993)
Blood
, vol.82
, pp. 2693-2703
-
-
Kunicki, T.J.1
Orchekowski, R.2
Annis, D.3
Honda, Y.4
-
81
-
-
33745043235
-
Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1
-
Lebbink RJ, de RT, Adelmeijer J, Brenkman AB, van Helvoort JM, Koch M, Farndale RW, Lisman T, Sonnenberg A, Lenting PJ, Meyaard L (2006) Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1. J Exp Med 203:1419-1425
-
(2006)
J Exp Med
, vol.203
, pp. 1419-1425
-
-
Lebbink, R.J.1
De Rt Adelmeijer, J.2
Brenkman, A.B.3
Van Helvoort, J.M.4
Koch, M.5
Farndale, R.W.6
Lisman, T.7
Sonnenberg, A.8
Lenting, P.J.9
Meyaard, L.10
-
82
-
-
1542755135
-
Human platelet glycoprotein VI function is antagonized by monoclonal anti bodyderived Fab fragments
-
Lecut C, Feeney LA, Kingsbury G, Hopkins J, Lanza F, Gachet C, Villeval JL, Jandrot-Perrus M (2003) Human platelet glycoprotein VI function is antagonized by monoclonal anti bodyderived Fab fragments. J Thromb Haemost 1:2653-2662
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2653-2662
-
-
Lecut, C.1
Feeney, L.A.2
Kingsbury, G.3
Hopkins, J.4
Lanza, F.5
Gachet, C.6
Villeval, J.L.7
Jandrot-Perrus, M.8
-
83
-
-
77957867626
-
Efficient inhibition of collagen-induced platelet activation and adhesion by LAIR-2, a soluble Ig-like receptor family member
-
Lenting PJ, Westerlaken GH, Denis CV, Akkerman JW, Meyaard L (2010) Efficient inhibition of collagen-induced platelet activation and adhesion by LAIR-2, a soluble Ig-like receptor family member. PLoS One 5:e12174
-
(2010)
PLoS One
, vol.5
-
-
Lenting, P.J.1
Westerlaken, G.H.2
Denis, C.V.3
Akkerman, J.W.4
Meyaard, L.5
-
84
-
-
34247398257
-
The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats
-
Li H, Lockyer S, Concepcion A, Gong X, Takizawa H, Guertin M, Matsumoto Y, Kambayashi J, Tandon NN, Liu Y (2007) The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats. Arterioscler Thromb Vasc Biol 27:1199-1205
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1199-1205
-
-
Li, H.1
Lockyer, S.2
Concepcion, A.3
Gong, X.4
Takizawa, H.5
Guertin, M.6
Matsumoto, Y.7
Kambayashi, J.8
Tandon, N.N.9
Liu, Y.10
-
85
-
-
0037166284
-
Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI
-
Locke D, Chen H, Liu Y, Liu C, Kahn ML (2002) Lipid rafts orchestrate signaling by the platelet receptor glycoprotein VI. J Biol Chem 277:18801-18809
-
(2002)
J Biol Chem
, vol.277
, pp. 18801-18809
-
-
Locke, D.1
Chen, H.2
Liu, Y.3
Liu, C.4
Kahn, M.L.5
-
86
-
-
33746028224
-
GPVI-deficient mice lack collagen responses and are protected against experimentally induced pulmonary thromboembolism
-
Lockyer S, Okuyama K, Begum S, Le S, Sun B, Watanabe T, Matsumoto Y, Yoshitake M, Kambayashi J, Tandon NN (2006) GPVI-deficient mice lack collagen responses and are protected against experimentally induced pulmonary thromboembolism. Thromb Res 118:371-380
-
(2006)
Thromb Res
, vol.118
, pp. 371-380
-
-
Lockyer, S.1
Okuyama, K.2
Begum, S.3
Le Sun, S.B.4
Watanabe, T.5
Matsumoto, Y.6
Yoshitake, M.7
Kambayashi, J.8
Tandon, N.N.9
-
87
-
-
34247891506
-
Structural basis of integrin regulation and signaling
-
Luo BH, Carman CV, Springer TA (2007) Structural basis of integrin regulation and signaling. Annu Rev Immunol 25:619-647
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 619-647
-
-
Luo, B.H.1
Carman, C.V.2
Springer, T.A.3
-
88
-
-
33744455164
-
Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency
-
Mangin P, Yap CL, Nonne C, Sturgeon SA, Goncalves I, Yuan Y, Schoenwaelder SM, Wright CE, Lanza F, Jackson SP (2006) Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency. Blood 107:4346-4353
-
(2006)
Blood
, vol.107
, pp. 4346-4353
-
-
Mangin, P.1
Yap, C.L.2
Nonne, C.3
Sturgeon, S.A.4
Goncalves, I.5
Yuan, Y.6
Schoenwaelder, S.M.7
Wright, C.E.8
Lanza, F.9
Jackson, S.P.10
-
89
-
-
1442290149
-
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo
-
Massberg S, Konrad I, Bultmann A, Schulz C, Munch G, Peluso M, Lorenz M, Schneider S, Besta F, Muller I, Hu B, Langer H, Kremmer E, Rudelius M, Heinzmann U, Ungerer M, Gawaz M (2004) Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. FASEB J 18:397-399
-
(2004)
FASEB J
, vol.18
, pp. 397-399
-
-
Massberg, S.1
Konrad, I.2
Bultmann, A.3
Schulz, C.4
Munch, G.5
Peluso, M.6
Lorenz, M.7
Schneider, S.8
Besta, F.9
Muller, I.10
Hu, B.11
Langer, H.12
Kremmer, E.13
Rudelius, M.14
Heinzmann, U.15
Ungerer, M.16
Gawaz, M.17
-
90
-
-
0037240588
-
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo
-
Massberg S, Gawaz M, Gruner S, Schulte V, Konrad I, Zohlnhofer D, Heinzmann U, Nieswandt B (2003) A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. J Exp Med 197:41-49
-
(2003)
J Exp Med
, vol.197
, pp. 41-49
-
-
Massberg, S.1
Gawaz, M.2
Gruner, S.3
Schulte, V.4
Konrad, I.5
Zohlnhofer, D.6
Heinzmann, U.7
Nieswandt, B.8
-
91
-
-
32044458448
-
Ex vivo evaluation of anti-GPVI antibody in cynomolgus monkeys: Dissociation between antiplatelet aggregatory effect and bleeding time
-
Matsumoto Y, Takizawa H, Nakama K, Gong X, Yamada Y, Tandon NN, Kambayashi J (2006) Ex vivo evaluation of anti-GPVI antibody in cynomolgus monkeys: dissociation between antiplatelet aggregatory effect and bleeding time. Thromb Haemost 96:167-175
-
(2006)
Thromb Haemost
, vol.96
, pp. 167-175
-
-
Matsumoto, Y.1
Takizawa, H.2
Nakama, K.3
Gong, X.4
Yamada, Y.5
Tandon, N.N.6
Kambayashi, J.7
-
92
-
-
29144432855
-
Antithrombotic effect of the type III collagen-related octapeptide (KOGEOGPK) in the mouse
-
Maurice P, Pires V, Amant C, Kauskot A, Da NS, Sonnet P, Rochette J, Legrand C, Fauvel-Lafeve F, Bonnefoy A (2006) Antithrombotic effect of the type III collagen-related octapeptide (KOGEOGPK) in the mouse. Vascul Pharmacol 44:42-49
-
(2006)
Vascul Pharmacol
, vol.44
, pp. 42-49
-
-
Maurice, P.1
Pires, V.2
Amant, C.3
Kauskot, A.4
Da Sonnet, N.S.P.5
Rochette, J.6
Legrand, C.7
Fauvel-Lafeve, F.8
Bonnefoy, A.9
-
93
-
-
58849165421
-
Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism
-
Miller MW, Basra S, Kulp DW, Billings PC, Choi S, Beavers MP, McCarty OJ, Zou Z, Kahn ML, Bennett JS, DeGrado WF (2009) Small-molecule inhibitors of integrin alpha2beta1 that prevent pathological thrombus formation via an allosteric mechanism. Proc Natl Acad Sci U S A 106:719-724
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 719-724
-
-
Miller, M.W.1
Basra, S.2
Kulp, D.W.3
Billings, P.C.4
Choi, S.5
Beavers, M.P.6
McCarty, O.J.7
Zou, Z.8
Kahn, M.L.9
Bennett, J.S.10
Degrado, W.F.11
-
94
-
-
0026643696
-
Distribution of the collagen binding heatshock protein in chicken tissues
-
Miyaishi O, Sakata K, Matsuyama M, Saga S (1992) Distribution of the collagen binding heatshock protein in chicken tissues. J Histochem Cytochem 40:1021-1029
-
(1992)
J Histochem Cytochem
, vol.40
, pp. 1021-1029
-
-
Miyaishi, O.1
Sakata, K.2
Matsuyama, M.3
Saga, S.4
-
95
-
-
0034646596
-
A new platelet receptor specific to type III collagen. Type III collagen-binding protein
-
Monnet E, Fauvel-Lafeve F (2000) A new platelet receptor specific to type III collagen. Type III collagen-binding protein. J Biol Chem 275:10912-10917
-
(2000)
J Biol Chem
, vol.275
, pp. 10912-10917
-
-
Monnet, E.1
Fauvel-Lafeve, F.2
-
96
-
-
0034910567
-
A monoclonal antibody to platelet type III collagen-binding protein (TIIICBP) binds to blood and vascular cells, and inhibits platelet vessel-wall interactions
-
Monnet E, Depraetere H, Legrand C, Deckmyn H, Fauvel-Lafeve F (2001) A monoclonal antibody to platelet type III collagen-binding protein (TIIICBP) binds to blood and vascular cells, and inhibits platelet vessel-wall interactions. Thromb Haemost 86:694-701
-
(2001)
Thromb Haemost
, vol.86
, pp. 694-701
-
-
Monnet, E.1
Depraetere, H.2
Legrand, C.3
Deckmyn, H.4
Fauvel-Lafeve, F.5
-
97
-
-
0035883095
-
Platelet glycoprotein v binds to collagen and participates in platelet adhesion and aggregation
-
Moog S, Mangin P, Lenain N, Strassel C, Ravanat C, Schuhler S, Freund M, Santer M, Kahn M, Nieswandt B, Gachet C, Cazenave JP, Lanza F (2001) Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation. Blood 98:1038-1046
-
(2001)
Blood
, vol.98
, pp. 1038-1046
-
-
Moog, S.1
Mangin, P.2
Lenain, N.3
Strassel, C.4
Ravanat, C.5
Schuhler, S.6
Freund, M.7
Santer, M.8
Kahn, M.9
Nieswandt, B.10
Gachet, C.11
Cazenave, J.P.12
Lanza, F.13
-
98
-
-
0001218842
-
Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: A case-control study
-
Moshfegh K, Wuillemin WA, Redondo M, Lammle B, Beer JH, Liechti-Gallati S, Meyer BJ (1999) Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: a case-control study. Lancet 353:351-354
-
(1999)
Lancet
, vol.353
, pp. 351-354
-
-
Moshfegh, K.1
Wuillemin, W.A.2
Redondo, M.3
Lammle, B.4
Beer, J.H.5
Liechti-Gallati, S.6
Meyer, B.J.7
-
99
-
-
39149086659
-
Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases
-
Moura-da-Silva AM, Ramos OH, Baldo C, Niland S, Hansen U, Ventura JS, Furlan S, Butera D, la-Casa MS, Tanjoni I, Clissa PB, Fernandes I, Chudzinski-Tavassi AM, Eble JA (2008) Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases. Biochimie 90:484-492
-
(2008)
Biochimie
, vol.90
, pp. 484-492
-
-
Moura-Da-Silva, A.M.1
Ramos, O.H.2
Baldo, C.3
Niland, S.4
Hansen, U.5
Ventura, J.S.6
Furlan, S.7
Butera, D.8
La-Casa, M.S.9
Tanjoni, I.10
Clissa, P.B.11
Fernandes, I.12
Chudzinski-Tavassi, A.M.13
Eble, J.A.14
-
100
-
-
68149163242
-
Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro
-
Muzard J, Bouabdelli M, Zahid M, Ollivier V, Lacapere JJ, Jandrot-Perrus M, Billiald P (2009) Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro. FEBS J 276:4207-4222
-
(2009)
FEBS J
, vol.276
, pp. 4207-4222
-
-
Muzard, J.1
Bouabdelli, M.2
Zahid, M.3
Ollivier, V.4
Lacapere, J.J.5
Jandrot-Perrus, M.6
Billiald, P.7
-
101
-
-
17744381152
-
Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen
-
Nieswandt B, Brakebusch C, Bergmeier W, Schulte V, Bouvard D, Mokhtari-Nejad R, Lindhout T, Heemskerk JW, Zirngibl H, Fassler R (2001b) Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen. EMBO J 20:2120-2130
-
(2001)
EMBO J
, vol.20
, pp. 2120-2130
-
-
Nieswandt, B.1
Brakebusch, C.2
Bergmeier, W.3
Schulte, V.4
Bouvard, D.5
Mokhtari-Nejad, R.6
Lindhout, T.7
Heemskerk, J.W.8
Zirngibl, H.9
Fassler, R.10
-
102
-
-
0035910757
-
Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice
-
Nieswandt B, Schulte V, Bergmeier W, Mokhtari-Nejad R, Rackebrandt K, Cazenave JP, Ohlmann P, Gachet C, Zirngibl H (2001a) Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice. J Exp Med 193:459-469
-
(2001)
J Exp Med
, vol.193
, pp. 459-469
-
-
Nieswandt, B.1
Schulte, V.2
Bergmeier, W.3
Mokhtari-Nejad, R.4
Rackebrandt, K.5
Cazenave, J.P.6
Ohlmann, P.7
Gachet, C.8
Zirngibl, H.9
-
103
-
-
0022353697
-
Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia
-
Nieuwenhuis HK, Akkerman JW, Houdijk WP, Sixma JJ (1985) Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia. Nature 318:470-472
-
(1985)
Nature
, vol.318
, pp. 470-472
-
-
Nieuwenhuis, H.K.1
Akkerman, J.W.2
Houdijk, W.P.3
Sixma, J.J.4
-
104
-
-
75749147056
-
A small-molecule inhibitor of integrin alpha2 beta1 introduces a new strategy for antithrombotic therapy
-
Nissinen L, Pentikainen OT, Jouppila A, Kapyla J, Ojala M, Nieminen J, Lipsanen A, Lappalainen H, Eckes B, Johnson MS, Lassila R, Marjamaki A, Heino J (2010) A small-molecule inhibitor of integrin alpha2 beta1 introduces a new strategy for antithrombotic therapy. Thromb Haemost 103:387-397
-
(2010)
Thromb Haemost
, vol.103
, pp. 387-397
-
-
Nissinen, L.1
Pentikainen, O.T.2
Jouppila, A.3
Kapyla, J.4
Ojala, M.5
Nieminen, J.6
Lipsanen, A.7
Lappalainen, H.8
Eckes, B.9
Johnson, M.S.10
Lassila, R.11
Marjamaki, A.12
Heino, J.13
-
105
-
-
4043152900
-
Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men
-
Ollikainen E, Mikkelsson J, Perola M, Penttila A, Karhunen PJ (2004) Platelet membrane collagen receptor glycoprotein VI polymorphism is associated with coronary thrombosis and fatal myocardial infarction in middle-aged men. Atherosclerosis 176:95-99
-
(2004)
Atherosclerosis
, vol.176
, pp. 95-99
-
-
Ollikainen, E.1
Mikkelsson, J.2
Perola, M.3
Penttila, A.4
Karhunen, P.J.5
-
106
-
-
0039552136
-
"rKKH" peptides from the snake venom metalloproteinase of Bothrops jararaca bind near the metal iondependent adhesion site of the human integrin alpha(2) I-domain
-
Pentikainen O, Hoffren AM, Ivaska J, Kapyla J, Nyronen T, Heino J, Johnson MS (1999) "RKKH" peptides from the snake venom metalloproteinase of Bothrops jararaca bind near the metal iondependent adhesion site of the human integrin alpha(2) I-domain. J Biol Chem 274:31493-31505
-
(1999)
J Biol Chem
, vol.274
, pp. 31493-31505
-
-
Pentikainen, O.1
Hoffren, A.M.2
Ivaska, J.3
Kapyla, J.4
Nyronen, T.5
Heino, J.6
Johnson, M.S.7
-
107
-
-
20444431568
-
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI
-
Penz S, Reininger AJ, Brandl R, Goyal P, Rabie T, Bernlochner I, Rother E, Goetz C, Engelmann B, Smethurst PA, Ouwehand WH, Farndale R, Nieswandt B, Siess W (2005) Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI. FASEB J 19:898-909
-
(2005)
FASEB J
, vol.19
, pp. 898-909
-
-
Penz, S.1
Reininger, A.J.2
Brandl, R.3
Goyal, P.4
Rabie, T.5
Bernlochner, I.6
Rother, E.7
Goetz, C.8
Engelmann, B.9
Smethurst, P.A.10
Ouwehand, W.H.11
Farndale, R.12
Nieswandt, B.13
Siess, W.14
-
108
-
-
77953922179
-
Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood
-
Pugh N, Simpson AM, Smethurst PA, de Groot PG, Raynal N, Farndale RW (2010) Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood. Blood 115:5069-5079
-
(2010)
Blood
, vol.115
, pp. 5069-5079
-
-
Pugh, N.1
Simpson, A.M.2
Smethurst, P.A.3
De Groot, P.G.4
Raynal, N.5
Farndale, R.W.6
-
109
-
-
0034672357
-
Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
-
Quek LS, Pasquet JM, Hers I, Cornall R, Knight G, Barnes M, Hibbs ML, Dunn AR, Lowell CA, Watson SP (2000) Fyn and Lyn phosphorylate the Fc receptor gamma chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway. Blood 96:4246-4253
-
(2000)
Blood
, vol.96
, pp. 4246-4253
-
-
Quek, L.S.1
Pasquet, J.M.2
Hers, I.3
Cornall, R.4
Knight, G.5
Barnes, M.6
Hibbs, M.L.7
Dunn, A.R.8
Lowell, C.A.9
Watson, S.P.10
-
110
-
-
17644419365
-
Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein v
-
Rabie T, Strehl A, Ludwig A, Nieswandt B (2005) Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V. J Biol Chem 280:14462-14468
-
(2005)
J Biol Chem
, vol.280
, pp. 14462-14468
-
-
Rabie, T.1
Strehl, A.2
Ludwig, A.3
Nieswandt, B.4
-
111
-
-
33645218408
-
Use of synthetic peptides to locate novel integrin alpha (2) beta (1)-binding motifs in human collagen III
-
Raynal N, Hamaia SW, Siljander PRM, Maddox B, Peachey AR, Fernandez R, Foley LJ, Slatter DA, Jarvis GE, Farndale RW (2006) Use of synthetic peptides to locate novel integrin alpha(2) beta(1)-binding motifs in human collagen III. J Biol Chem 281:3821-3831
-
(2006)
J Biol Chem
, vol.281
, pp. 3821-3831
-
-
Raynal, N.1
Hamaia, S.W.2
Prm, S.3
Maddox, B.4
Peachey, A.R.5
Fernandez, R.6
Foley, L.J.7
Slatter, D.A.8
Jarvis, G.E.9
Farndale, R.W.10
-
112
-
-
43749115532
-
Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex
-
Riba R, Hughes CE, Graham A, Watson SP, Naseem KM (2008) Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex. J Thromb Haemost 6:1012-1020
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1012-1020
-
-
Riba, R.1
Hughes, C.E.2
Graham, A.3
Watson, S.P.4
Naseem, K.M.5
-
113
-
-
0027972576
-
Platelet adhesion to collagen types i through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)
-
Saelman EU, Nieuwenhuis HK, Hese KM, de Groot PG, Heijnen HF, Sage EH, Williams S, McKeown L, Gralnick HR, Sixma JJ (1994) Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin). Blood 83:1244-1250
-
(1994)
Blood
, vol.83
, pp. 1244-1250
-
-
Saelman, E.U.1
Nieuwenhuis, H.K.2
Hese, K.M.3
De Groot, P.G.4
Heijnen, H.F.5
Sage, E.H.6
Williams, S.7
McKeown, L.8
Gralnick, H.R.9
Sixma, J.J.10
-
114
-
-
0033561354
-
Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients
-
Santoso S, Kunicki TJ, Kroll H, Haberbosch W, Gardemann A (1999) Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood 93:2449-2453
-
(1999)
Blood
, vol.93
, pp. 2449-2453
-
-
Santoso, S.1
Kunicki, T.J.2
Kroll, H.3
Haberbosch, W.4
Gardemann, A.5
-
115
-
-
33744954589
-
A new nucleoside derivative, AJP117510, as an inhibitor of integrin alpha2beta1-collagen binding
-
Sato S, Futaki F, Fukuchi N, Kaida K, Hiraga M, Kobaru S, Tsuji T (2006) A new nucleoside derivative, AJP117510, as an inhibitor of integrin alpha2beta1-collagen binding. J Antibiot (Tokyo) 59:251-253
-
(2006)
J Antibiot (Tokyo)
, vol.59
, pp. 251-253
-
-
Sato, S.1
Futaki, F.2
Fukuchi, N.3
Kaida, K.4
Hiraga, M.5
Kobaru, S.6
Tsuji, T.7
-
116
-
-
0027421698
-
Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons
-
Schaffer LW, Davidson JT, Siegl PK, Gould RJ, Nutt RF, Brady SF, Connolly TM (1993) Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons. Arterioscler Thromb 13:1593-1601
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 1593-1601
-
-
Schaffer, L.W.1
Davidson, J.T.2
Siegl, P.K.3
Gould, R.J.4
Nutt, R.F.5
Brady, S.F.6
Connolly, T.M.7
-
117
-
-
75849146048
-
Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role
-
Schmaier AA, Zou Z, Kazlauskas A, Emert-Sedlak L, Fong KP, Neeves KB, Maloney SF, Diamond SL, Kunapuli SP, Ware J, Brass LF, Smithgall TE, Saksela K, Kahn ML (2009) Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proc Natl Acad Sci USA 106:21167-21172
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21167-21172
-
-
Schmaier, A.A.1
Zou, Z.2
Kazlauskas, A.3
Emert-Sedlak, L.4
Fong, K.P.5
Neeves, K.B.6
Maloney, S.F.7
Diamond, S.L.8
Kunapuli, S.P.9
Ware, J.10
Brass, L.F.11
Smithgall, T.E.12
Saksela, K.13
Kahn, M.L.14
-
118
-
-
33745939987
-
Two-phase antithrombotic protection after anti-glycoprotein VI treatment in mice
-
Schulte V, Reusch HP, Pozgajova M, Varga-Szabo D, Gachet C, Nieswandt B (2006) Two-phase antithrombotic protection after anti-glycoprotein VI treatment in mice. Arterioscler Thromb Vasc Biol 26:1640-1647
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 1640-1647
-
-
Schulte, V.1
Reusch, H.P.2
Pozgajova, M.3
Varga-Szabo, D.4
Gachet, C.5
Nieswandt, B.6
-
119
-
-
0842328842
-
Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood
-
Siljander PRM, Munnix ICA, Smethurst PA, Deckmyn H, Lindhout T, Ouwehand WH, Farndale RW, Heemskerk JWM (2004) Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood. Blood 103:1333-1341
-
(2004)
Blood
, vol.103
, pp. 1333-1341
-
-
Prm, S.1
Munnix, I.C.A.2
Smethurst, P.A.3
Deckmyn, H.4
Lindhout, T.5
Ouwehand, W.H.6
Farndale, R.W.7
Heemskerk, J.W.M.8
-
120
-
-
33847736329
-
Structural basis for the platelet-collagen interaction: The smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycineproline- hydroxyproline triplets
-
Smethurst PA, Onley DJ, Jarvis GE, O'Connor MN, Knight CG, Herr AB, Ouwehand WH, Farndale RW (2007) Structural basis for the platelet-collagen interaction: the smallest motif within collagen that recognizes and activates platelet Glycoprotein VI contains two glycineproline- hydroxyproline triplets. J Biol Chem 282:1296-1304
-
(2007)
J Biol Chem
, vol.282
, pp. 1296-1304
-
-
Smethurst, P.A.1
Onley, D.J.2
Jarvis, G.E.3
O'Connor, M.N.4
Knight, C.G.5
Herr, A.B.6
Ouwehand, W.H.7
Farndale, R.W.8
-
121
-
-
9144271618
-
Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
-
Smethurst PA, Joutsi-Korhonen L, O'Connor MN, Wilson E, Jennings NS, Garner SF, Zhang Y, Knight CG, Dafforn TR, Buckle A, Ijsseldijk MJ, de Groot PG, Watkins NA, Farndale RW, Ouwehand WH (2004) Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood 103:903-911
-
(2004)
Blood
, vol.103
, pp. 903-911
-
-
Smethurst, P.A.1
Joutsi-Korhonen, L.2
O'Connor, M.N.3
Wilson, E.4
Jennings, N.S.5
Garner, S.F.6
Zhang, Y.7
Knight, C.G.8
Dafforn, T.R.9
Buckle, A.10
Ijsseldijk, M.J.11
De Groot, P.G.12
Watkins, N.A.13
Farndale, R.W.14
Ouwehand, W.H.15
-
122
-
-
0023185207
-
A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia
-
Sugiyama T, Okuma M, Ushikubi F, Sensaki S, Kanaji K, Uchino H (1987) A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia. Blood 69:1712-1720
-
(1987)
Blood
, vol.69
, pp. 1712-1720
-
-
Sugiyama, T.1
Okuma, M.2
Ushikubi, F.3
Sensaki, S.4
Kanaji, K.5
Uchino, H.6
-
123
-
-
0037077263
-
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling
-
Suzuki-Inoue K, Tulasne D, Shen Y, Bori-Sanz T, Inoue O, Jung SM, Moroi M, Andrews RK, Berndt MC, Watson SP (2002) Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem 277:21561-21566
-
(2002)
J Biol Chem
, vol.277
, pp. 21561-21566
-
-
Suzuki-Inoue, K.1
Tulasne, D.2
Shen, Y.3
Bori-Sanz, T.4
Inoue, O.5
Jung, S.M.6
Moroi, M.7
Andrews, R.K.8
Berndt, M.C.9
Watson, S.P.10
-
124
-
-
43049116482
-
A novel antiplatelet antibody therapy that induces cAMP-dependent endocytosis of the GPVI/Fc receptor gamma-chain complex
-
Takayama H, Hosaka Y, Nakayama K, Shirakawa K, Naitoh K, Matsusue T, Shinozaki M, Honda M, Yatagai Y, Kawahara T, Hirose J, Yokoyama T, Kurihara M, Furusako S (2008) A novel antiplatelet antibody therapy that induces cAMP-dependent endocytosis of the GPVI/Fc receptor gamma-chain complex. J Clin Invest 118:1785-1795
-
(2008)
J Clin Invest
, vol.118
, pp. 1785-1795
-
-
Takayama, H.1
Hosaka, Y.2
Nakayama, K.3
Shirakawa, K.4
Naitoh, K.5
Matsusue, T.6
Shinozaki, M.7
Honda, M.8
Yatagai, Y.9
Kawahara, T.10
Hirose, J.11
Yokoyama, T.12
Kurihara, M.13
Furusako, S.14
-
125
-
-
77649335773
-
Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to alpha2beta1 integrin and collagen
-
Tanjoni I, Evangelista K, la-Casa MS, Butera D, Magalhaes GS, Baldo C, Clissa PB, Fernandes I, Eble J, Moura-da-Silva AM (2010) Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to alpha2beta1 integrin and collagen. Toxicon 55:1093-1099
-
(2010)
Toxicon
, vol.55
, pp. 1093-1099
-
-
Tanjoni, I.1
Evangelista, K.2
La-Casa, M.S.3
Butera, D.4
Magalhaes, G.S.5
Baldo, C.6
Clissa, P.B.7
Fernandes, I.8
Eble, J.9
Moura-Da-Silva, A.M.10
-
126
-
-
0032883044
-
Adhesive domains in the collagen III fragment alpha1(III)CB4 that support alpha2beta1- and von Willebrand factor-mediated platelet adhesion under flow conditions
-
Verkleij MW, Ijsseldijk MJ, Heijnen-Snyder GJ, Huizinga EG, Morton LF, Knight CG, Sixma JJ, de Groot PG, Barnes MJ (1999) Adhesive domains in the collagen III fragment alpha1(III)CB4 that support alpha2beta1- and von Willebrand factor-mediated platelet adhesion under flow conditions. Thromb Haemost 82:1137-1144
-
(1999)
Thromb Haemost
, vol.82
, pp. 1137-1144
-
-
Verkleij, M.W.1
Ijsseldijk, M.J.2
Heijnen-Snyder, G.J.3
Huizinga, E.G.4
Morton, L.F.5
Knight, C.G.6
Sixma, J.J.7
De Groot, P.G.8
Barnes, M.J.9
-
127
-
-
0032525269
-
Simple collagenlike peptides support platelet adhesion under static but not under flow conditions: Interaction via alpha2 beta1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces
-
Verkleij MW, Morton LF, Knight CG, de Groot PG, Barnes MJ, Sixma JJ (1998) Simple collagenlike peptides support platelet adhesion under static but not under flow conditions: interaction via alpha2 beta1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces. Blood 91:3808-3816
-
(1998)
Blood
, vol.91
, pp. 3808-3816
-
-
Verkleij, M.W.1
Morton, L.F.2
Knight, C.G.3
De Groot, P.G.4
Barnes, M.J.5
Sixma, J.J.6
-
128
-
-
3543012561
-
Antithrombotic effects of saratin on human atherosclerotic plaques
-
Vilahur G, Duran X, Juan-Babot O, Casani L, Badimon L (2004) Antithrombotic effects of saratin on human atherosclerotic plaques. Thromb Haemost 92:191-200
-
(2004)
Thromb Haemost
, vol.92
, pp. 191-200
-
-
Vilahur, G.1
Duran, X.2
Juan-Babot, O.3
Casani, L.4
Badimon, L.5
-
129
-
-
67651162031
-
Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation
-
Walker A, Pugh N, Garner SF, Stephens J, Maddox B, Ouwehand WH, Farndale RW, Steward M (2009) Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation. Platelets 20:268-276
-
(2009)
Platelets
, vol.20
, pp. 268-276
-
-
Walker, A.1
Pugh, N.2
Garner, S.F.3
Stephens, J.4
Maddox, B.5
Ouwehand, W.H.6
Farndale, R.W.7
Steward, M.8
-
130
-
-
27644597567
-
Primary structure and antiplatelet mechanism of a snake venom metalloproteinase, acurhagin, from Agkistrodon acutus venom
-
Wang WJ, Shih CH, Huang TF (2005) Primary structure and antiplatelet mechanism of a snake venom metalloproteinase, acurhagin, from Agkistrodon acutus venom. Biochimie 87:1065-1077
-
(2005)
Biochimie
, vol.87
, pp. 1065-1077
-
-
Wang, W.J.1
Shih, C.H.2
Huang, T.F.3
-
132
-
-
36949021367
-
Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI
-
Wijeyewickrema LC, Gardiner EE, Moroi M, Berndt MC, Andrews RK (2007) Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI. Thromb Haemost 98:1285-1290
-
(2007)
Thromb Haemost
, vol.98
, pp. 1285-1290
-
-
Wijeyewickrema, L.C.1
Gardiner, E.E.2
Moroi, M.3
Berndt, M.C.4
Andrews, R.K.5
-
133
-
-
18444401417
-
Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets
-
Wonerow P, Obergfell A, Wilde JI, Bobe R, Asazuma N, Brdicka T, Leo A, Schraven B, Horejsi V, Shattil SJ, Watson SP (2002) Differential role of glycolipid-enriched membrane domains in glycoprotein VI- and integrin-mediated phospholipase Cgamma2 regulation in platelets. Biochem J 364:755-765
-
(2002)
Biochem J
, vol.364
, pp. 755-765
-
-
Wonerow, P.1
Obergfell, A.2
Wilde, J.I.3
Bobe, R.4
Asazuma, N.5
Brdicka, T.6
Leo, A.7
Schraven, B.8
Horejsi, V.9
Shattil, S.J.10
Watson, S.P.11
-
134
-
-
55549097424
-
Salvianolic acid B inhibits platelet adhesion under conditions of flow by a mechanism involving the collagen receptor alpha2beta1
-
Wu YP, Zhao XM, Pan SD, Guo dA, Wei R, Han JJ, Kainoh M, Xia ZL, de Groot PG, Lisman T (2008) Salvianolic acid B inhibits platelet adhesion under conditions of flow by a mechanism involving the collagen receptor alpha2beta1. Thromb Res 123:298-305
-
(2008)
Thromb Res
, vol.123
, pp. 298-305
-
-
Wu, Y.P.1
Zhao, X.M.2
Pan, S.D.3
Da, G.4
Wei, R.5
Han, J.J.6
Kainoh, M.7
Xia, Z.L.8
De Groot, P.G.9
Lisman, T.10
-
135
-
-
33646852781
-
Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type i collagen interaction
-
Yin H, Gerlach LO, Miller MW, Moore DT, Liu D, Vilaire G, Bennett JS, DeGrado WF (2006) Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction. Bioorg Med Chem Lett 16:3380-3382
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 3380-3382
-
-
Yin, H.1
Gerlach, L.O.2
Miller, M.W.3
Moore, D.T.4
Liu, D.5
Vilaire, G.6
Bennett, J.S.7
Degrado, W.F.8
-
136
-
-
74249089187
-
A new oral antiplatelet agent with potent antithrombotic properties: Comparison of DZ-697b with clopidogrel a randomised phase i study
-
Zafar MU, Ibanez B, Choi BG, Vorchheimer DA, Pinero A, Jin X, Sharma RK, Badimon JJ (2010) A new oral antiplatelet agent with potent antithrombotic properties: comparison of DZ-697b with clopidogrel a randomised phase I study. Thromb Haemost 103:205-212
-
(2010)
Thromb Haemost
, vol.103
, pp. 205-212
-
-
Zafar, M.U.1
Ibanez, B.2
Choi, B.G.3
Vorchheimer, D.A.4
Pinero, A.5
Jin, X.6
Sharma, R.K.7
Badimon, J.J.8
-
137
-
-
33750798089
-
Type i and type III collagen-platelet interaction: Inhibition by type specific receptor peptides
-
Zhu J, Cole F, Woo-Rasberry V, Fang XR, Chiang TM (2007) Type I and type III collagen-platelet interaction: inhibition by type specific receptor peptides. Thromb Res 119:111-119
-
(2007)
Thromb Res
, vol.119
, pp. 111-119
-
-
Zhu, J.1
Cole, F.2
Woo-Rasberry, V.3
Fang, X.R.4
Chiang, T.M.5
-
138
-
-
27844567043
-
Platelet viscous metamorphosis produced by connective tissue particles
-
Zucker MB, Borrelli J (1961) Platelet viscous metamorphosis produced by connective tissue particles. Fed Proc 20:61
-
(1961)
Fed Proc
, vol.20
, pp. 61
-
-
Zucker, M.B.1
Borrelli, J.2
|