Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro

FEBS Journal

Volumn 276, Issue 15, 2009, Pages 4207-4222

  Muzard, Julien ^a,b   Bouabdelli, Maxime ^b   Zahid, Muhammad ^c   Ollivier, Véronique ^b   Lacapère, Jean Jacques ^b   Jandrot Perrus, Martine ^b   Billiald, Philippe ^a,c  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Antibody humanization; Arterial thrombosis; Collagen; Platelet

Indexed keywords

COLLAGEN; GLYCOPROTEIN VI; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 9012; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTERY BLOOD FLOW; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BINDING; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PURIFICATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION;

MURINAE;

EID: 68149163242     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07129.x     Document Type: Article

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