메뉴 건너뛰기




Volumn 252, Issue 1-2, 2012, Pages 66-74

Therapeutic effects of anti-Delta1 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease

Author keywords

Delta like 1 (Delta1); Demyelinating disease; Multiple sclerosis (MS); Notch signaling; Theiler's murine encephalomyelitis virus (TMEV)

Indexed keywords

CD4 ANTIGEN; CELL PROTEIN; DELTA LIKE 1 MONOCLONAL ANTIBODY; DELTA LIKE 1 PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; MESSENGER RNA; MONOCLONAL ANTIBODY; NOTCH RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84867140232     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2012.08.003     Document Type: Article
Times cited : (9)

References (57)
  • 1
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • Amsen D., Blander J.M., Lee G.R., Tanigaki K., Honjo T., Flavell R.A. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 2004, 117:515-526.
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1    Blander, J.M.2    Lee, G.R.3    Tanigaki, K.4    Honjo, T.5    Flavell, R.A.6
  • 3
    • 0030970058 scopus 로고    scopus 로고
    • Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
    • Benveniste E.N. Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J. Mol. Med. 1997, 75:165-173.
    • (1997) J. Mol. Med. , vol.75 , pp. 165-173
    • Benveniste, E.N.1
  • 4
    • 0025304856 scopus 로고
    • Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV)
    • Clatch R.J., Miller S.D., Metzner R., Dal Canto M.C., Lipton H.L. Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV). Virology 1990, 176:244-254.
    • (1990) Virology , vol.176 , pp. 244-254
    • Clatch, R.J.1    Miller, S.D.2    Metzner, R.3    Dal Canto, M.C.4    Lipton, H.L.5
  • 5
    • 0038282518 scopus 로고    scopus 로고
    • Toll-like receptors and T-helper-1/T-helper-2 responses
    • Dabbagh K., Lewis D.B. Toll-like receptors and T-helper-1/T-helper-2 responses. Curr. Opin. Infect. Dis. 2003, 16:199-204.
    • (2003) Curr. Opin. Infect. Dis. , vol.16 , pp. 199-204
    • Dabbagh, K.1    Lewis, D.B.2
  • 6
  • 9
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis-the plaque and its pathogenesis
    • Frohman E.M., Racke M.K., Raine C.S. Multiple sclerosis-the plaque and its pathogenesis. N. Engl. J. Med. 2006, 354:942-955.
    • (2006) N. Engl. J. Med. , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 10
    • 0028212497 scopus 로고
    • Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice
    • Gerety S.J., Karpus W.J., Cubbon A.R., Goswami R.G., Rundell M.K., Peterson J.D., Miller S.D. Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice. J. Immunol. 1994, 152:908-918.
    • (1994) J. Immunol. , vol.152 , pp. 908-918
    • Gerety, S.J.1    Karpus, W.J.2    Cubbon, A.R.3    Goswami, R.G.4    Rundell, M.K.5    Peterson, J.D.6    Miller, S.D.7
  • 11
    • 0030018923 scopus 로고    scopus 로고
    • The level of tumor necrosis factor-alpha producing cells in the spinal cord correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Inoue A., Koh C.S., Yahikozawa H., Yanagisawa N., Yagita H., Ishihara Y., Kim B.S. The level of tumor necrosis factor-alpha producing cells in the spinal cord correlates with the degree of Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int. Immunol. 1996, 8:1001-1008.
    • (1996) Int. Immunol. , vol.8 , pp. 1001-1008
    • Inoue, A.1    Koh, C.S.2    Yahikozawa, H.3    Yanagisawa, N.4    Yagita, H.5    Ishihara, Y.6    Kim, B.S.7
  • 12
    • 79958721221 scopus 로고    scopus 로고
    • Th17 cell, the new player of neuroinflammatory process in multiple sclerosis
    • Jadidi-Niaragh F., Mirshafiey A. Th17 cell, the new player of neuroinflammatory process in multiple sclerosis. Scand. J. Immunol. 2011, 74:1-13.
    • (2011) Scand. J. Immunol. , vol.74 , pp. 1-13
    • Jadidi-Niaragh, F.1    Mirshafiey, A.2
  • 13
    • 70350289945 scopus 로고    scopus 로고
    • + T cell response to RNA polymerase in susceptible SJL/J mice
    • + T cell response to RNA polymerase in susceptible SJL/J mice. J. Virol. 2009, 83:10981-10992.
    • (2009) J. Virol. , vol.83 , pp. 10981-10992
    • Jin, Y.H.1    Kang, B.2    Kim, B.S.3
  • 14
    • 0016646546 scopus 로고
    • The possible viral etiology of multiple sclerosis
    • Johnson R.T. The possible viral etiology of multiple sclerosis. Adv. Neurol. 1975, 13:1-46.
    • (1975) Adv. Neurol. , vol.13 , pp. 1-46
    • Johnson, R.T.1
  • 15
    • 77956917268 scopus 로고    scopus 로고
    • Tranilast modulates fibrosis, epithelial-mesenchymal transition and peritubular capillary injury in unilateral ureteral obstruction rats
    • Kaneyama T., Kobayashi S., Aoyagi D., Ehara T. Tranilast modulates fibrosis, epithelial-mesenchymal transition and peritubular capillary injury in unilateral ureteral obstruction rats. Pathology 2003, 42:564-573.
    • (2003) Pathology , vol.42 , pp. 564-573
    • Kaneyama, T.1    Kobayashi, S.2    Aoyagi, D.3    Ehara, T.4
  • 18
    • 34248217573 scopus 로고    scopus 로고
    • Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T cell suppression
    • Kostianovsky A.M., Maier L.M., Baecher-Allan C., Anderson A.C., Anderson D.E. Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T cell suppression. J. Immunol. 2007, 178:6158-6163.
    • (2007) J. Immunol. , vol.178 , pp. 6158-6163
    • Kostianovsky, A.M.1    Maier, L.M.2    Baecher-Allan, C.3    Anderson, A.C.4    Anderson, D.E.5
  • 19
    • 0021256645 scopus 로고
    • Theiler's virus antigen detected in mouse spinal cord 2 1/2 years after infection
    • Lipton H.L., Kratochvil J., Sethi P., Dal Canto M.C. Theiler's virus antigen detected in mouse spinal cord 2 1/2 years after infection. Neurology 1984, 34:1117-1119.
    • (1984) Neurology , vol.34 , pp. 1117-1119
    • Lipton, H.L.1    Kratochvil, J.2    Sethi, P.3    Dal Canto, M.C.4
  • 20
    • 7244219941 scopus 로고    scopus 로고
    • Quantitative, not qualitative, differences in CD8(+) T cell responses to Theiler's murine encephalomyelitis virus between resistant C57BL/6 and susceptible SJL/J mice
    • Lyman M.A., Myoung J., Mohindru M., Kim B.S. Quantitative, not qualitative, differences in CD8(+) T cell responses to Theiler's murine encephalomyelitis virus between resistant C57BL/6 and susceptible SJL/J mice. Eur. J. Immunol. 2004, 34:2730-2739.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2730-2739
    • Lyman, M.A.1    Myoung, J.2    Mohindru, M.3    Kim, B.S.4
  • 22
    • 17644382970 scopus 로고    scopus 로고
    • Regulation of lymphoid development, differentiation, and function by the Notch pathway
    • Maillard I., Fang T., Pear W.S. Regulation of lymphoid development, differentiation, and function by the Notch pathway. Annu. Rev. Immunol. 2005, 23:945-974.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 945-974
    • Maillard, I.1    Fang, T.2    Pear, W.S.3
  • 24
    • 33645976866 scopus 로고    scopus 로고
    • Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity
    • Monsalve E., Perez M.A., Rubio A., Ruiz-Hidalgo M.J., Baladron V., Garcia-Ramirez J.J., Gomez J.C., Laborda J., Diaz-Guerra M.J. Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. J. Immunol. 2006, 176:5362-5373.
    • (2006) J. Immunol. , vol.176 , pp. 5362-5373
    • Monsalve, E.1    Perez, M.A.2    Rubio, A.3    Ruiz-Hidalgo, M.J.4    Baladron, V.5    Garcia-Ramirez, J.J.6    Gomez, J.C.7    Laborda, J.8    Diaz-Guerra, M.J.9
  • 26
    • 43949122908 scopus 로고    scopus 로고
    • Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice
    • Myoung J., Bahk Y.Y., Kang H.S., Dal Canto M.C., Kim B.S. Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice. J. Virol. 2008, 82:5606-5617.
    • (2008) J. Virol. , vol.82 , pp. 5606-5617
    • Myoung, J.1    Bahk, Y.Y.2    Kang, H.S.3    Dal Canto, M.C.4    Kim, B.S.5
  • 27
    • 34247895422 scopus 로고    scopus 로고
    • Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
    • Nakae S., Iwakura Y., Suto H., Galli S.J. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol. 2007, 81:1258-1268.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 1258-1268
    • Nakae, S.1    Iwakura, Y.2    Suto, H.3    Galli, S.J.4
  • 28
    • 0019980359 scopus 로고
    • Multiple sclerosis (first of two parts)
    • McFarlin D.E., McFarland H.F. Multiple sclerosis (first of two parts). N. Engl. J. Med. 1982, 307:1183-1188.
    • (1982) N. Engl. J. Med. , vol.307 , pp. 1183-1188
    • McFarlin, D.E.1    McFarland, H.F.2
  • 32
    • 0029766872 scopus 로고    scopus 로고
    • Treatment with lipopolysaccharide enhances the pathogenicity of a low-pathogenic variant of Theiler's murine encephalomyelitis virus
    • Palma J.P., Park S.H., Kim B.S. Treatment with lipopolysaccharide enhances the pathogenicity of a low-pathogenic variant of Theiler's murine encephalomyelitis virus. J. Neurosci. Res. 1996, 45:776-785.
    • (1996) J. Neurosci. Res. , vol.45 , pp. 776-785
    • Palma, J.P.1    Park, S.H.2    Kim, B.S.3
  • 34
    • 0028670263 scopus 로고
    • Alteration in the level of interferon-gamma results in acceleration of Theiler's virus-induced demyelinating disease
    • Pullen L.C., Miller S.D., Dal Canto M.C., Van der Meide P.H., Kim B.S. Alteration in the level of interferon-gamma results in acceleration of Theiler's virus-induced demyelinating disease. J. Neuroimmunol. 1994, 55:143-152.
    • (1994) J. Neuroimmunol. , vol.55 , pp. 143-152
    • Pullen, L.C.1    Miller, S.D.2    Dal Canto, M.C.3    Van der Meide, P.H.4    Kim, B.S.5
  • 35
    • 0028793601 scopus 로고
    • Treatment with bacterial LPS renders genetically resistant C57BL/6 mice susceptible to Theiler's virus-induced demyelinating disease
    • Pullen L.C., Park S.H., Miller S.D., Dal Canto M.C., Kim B.S. Treatment with bacterial LPS renders genetically resistant C57BL/6 mice susceptible to Theiler's virus-induced demyelinating disease. J. Immunol. 1995, 155:4497-4503.
    • (1995) J. Immunol. , vol.155 , pp. 4497-4503
    • Pullen, L.C.1    Park, S.H.2    Miller, S.D.3    Dal Canto, M.C.4    Kim, B.S.5
  • 36
    • 0345432117 scopus 로고    scopus 로고
    • Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis
    • Rivera-Quiñones C., McGavern D., Schmelzer J.D., Hunter S.F., Low P.A., Rodriguez M. Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis. Nat. Med. 1998, 4:187-193.
    • (1998) Nat. Med. , vol.4 , pp. 187-193
    • Rivera-Quiñones, C.1    McGavern, D.2    Schmelzer, J.D.3    Hunter, S.F.4    Low, P.A.5    Rodriguez, M.6
  • 37
    • 0242268517 scopus 로고    scopus 로고
    • Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection
    • Rodriguez M., Zoecklein L.J., Howe C.L., Pavelko K.D., Gamez J.D., Nakane S., Papke L.M. Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection. J. Virol. 2003, 77:12252-12265.
    • (2003) J. Virol. , vol.77 , pp. 12252-12265
    • Rodriguez, M.1    Zoecklein, L.J.2    Howe, C.L.3    Pavelko, K.D.4    Gamez, J.D.5    Nakane, S.6    Papke, L.M.7
  • 39
    • 23844549973 scopus 로고    scopus 로고
    • Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells
    • Rutz S., Mordmuller B., Sakano S., Scheffold A. Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells. Eur. J. Immunol. 2005, 35:2443-2451.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 2443-2451
    • Rutz, S.1    Mordmuller, B.2    Sakano, S.3    Scheffold, A.4
  • 40
    • 34447254518 scopus 로고    scopus 로고
    • CD8- DCs induce IL-12-independent Th1 differentiation through Delta4 Notch-like ligand in response to bacterial LPS
    • Skokos D., Nussenzweig M.C. CD8- DCs induce IL-12-independent Th1 differentiation through Delta4 Notch-like ligand in response to bacterial LPS. J. Exp. Med. 2007, 204:1525-1531.
    • (2007) J. Exp. Med. , vol.204 , pp. 1525-1531
    • Skokos, D.1    Nussenzweig, M.C.2
  • 41
    • 69649097190 scopus 로고    scopus 로고
    • Theiler's virus infection induces TLR3-dependent upregulation of TLR2 critical for proinflammatory cytokine production
    • So E.Y., Kim B.S. Theiler's virus infection induces TLR3-dependent upregulation of TLR2 critical for proinflammatory cytokine production. Glia 2009, 57:1216-1226.
    • (2009) Glia , vol.57 , pp. 1216-1226
    • So, E.Y.1    Kim, B.S.2
  • 42
    • 33646516398 scopus 로고    scopus 로고
    • Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3
    • So E.Y., Kang M.H., Kim B.S. Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3. Glia 2006, 53:858-867.
    • (2006) Glia , vol.53 , pp. 858-867
    • So, E.Y.1    Kang, M.H.2    Kim, B.S.3
  • 44
    • 17644396349 scopus 로고    scopus 로고
    • Immunology of multiple sclerosis
    • Sospedra M., Martin R. Immunology of multiple sclerosis. Annu. Rev. Immunol. 2005, 23:683-747.
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 683-747
    • Sospedra, M.1    Martin, R.2
  • 45
    • 79953170980 scopus 로고    scopus 로고
    • IL-17-expressing cells as a potential therapeutic target for treatment of immunological disorders
    • Strzepa A., Szczepanik M. IL-17-expressing cells as a potential therapeutic target for treatment of immunological disorders. Pharmacol. Rep. 2011, 63:30-44.
    • (2011) Pharmacol. Rep. , vol.63 , pp. 30-44
    • Strzepa, A.1    Szczepanik, M.2
  • 46
    • 40749089559 scopus 로고    scopus 로고
    • Suppression of Th2 cell development by Notch ligands Delta1 and Delta4
    • Sun J., Krawczyk C.J., Pearce E.J. Suppression of Th2 cell development by Notch ligands Delta1 and Delta4. J. Immunol. 2008, 180:1655-1661.
    • (2008) J. Immunol. , vol.180 , pp. 1655-1661
    • Sun, J.1    Krawczyk, C.J.2    Pearce, E.J.3
  • 47
    • 77956107505 scopus 로고    scopus 로고
    • Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Takeichi N., Yanagisawa S., Kaneyama T., Yagita H., Jin Y.H., Kim B.S., Koh C.S. Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int. Immunol. 2010, 22:729-738.
    • (2010) Int. Immunol. , vol.22 , pp. 729-738
    • Takeichi, N.1    Yanagisawa, S.2    Kaneyama, T.3    Yagita, H.4    Jin, Y.H.5    Kim, B.S.6    Koh, C.S.7
  • 48
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 2003, 3:133-146.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 49
    • 10344222653 scopus 로고    scopus 로고
    • Notch governing mature T cell differentiation
    • Tsukumo S., Yasutomo K. Notch governing mature T cell differentiation. J. Immunol. 2004, 173:7109-7113.
    • (2004) J. Immunol. , vol.173 , pp. 7109-7113
    • Tsukumo, S.1    Yasutomo, K.2
  • 50
    • 33244471551 scopus 로고    scopus 로고
    • IFN-γ production and astrocyte recognition by autoreactive T cells induced by Theiler's virus infection: role of viral strains and capsid proteins
    • Tsunoda I., Libbey J.E., Kobayashi-Warren M., Fujinami R.S. IFN-γ production and astrocyte recognition by autoreactive T cells induced by Theiler's virus infection: role of viral strains and capsid proteins. J. Neuroimmunol. 2006, 172:85-93.
    • (2006) J. Neuroimmunol. , vol.172 , pp. 85-93
    • Tsunoda, I.1    Libbey, J.E.2    Kobayashi-Warren, M.3    Fujinami, R.S.4
  • 51
    • 20444382606 scopus 로고    scopus 로고
    • Direct and indirect role of Toll-like receptors in T cell mediated immunity
    • Xu D., Liu H., Komai-Koma M. Direct and indirect role of Toll-like receptors in T cell mediated immunity. Cell. Mol. Immunol. 2004, 1:239-246.
    • (2004) Cell. Mol. Immunol. , vol.1 , pp. 239-246
    • Xu, D.1    Liu, H.2    Komai-Koma, M.3
  • 52
    • 0036533175 scopus 로고    scopus 로고
    • Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice
    • Yamaguchi E., Chiba S., Kumano K., Kunisato A., Takahashi T., Hirai H. Expression of Notch ligands, Jagged1, 2 and Delta1 in antigen presenting cells in mice. Immunol. Lett. 2002, 81:59-64.
    • (2002) Immunol. Lett. , vol.81 , pp. 59-64
    • Yamaguchi, E.1    Chiba, S.2    Kumano, K.3    Kunisato, A.4    Takahashi, T.5    Hirai, H.6
  • 53
    • 0028020309 scopus 로고
    • A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244)
    • Yauch R.L., Kim B.S. A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244). J. Immunol. 1994, 153:4508-4519.
    • (1994) J. Immunol. , vol.153 , pp. 4508-4519
    • Yauch, R.L.1    Kim, B.S.2
  • 54
    • 0031747584 scopus 로고    scopus 로고
    • Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response
    • Yauch R.L., Palma J.P., Yahikozawa H., Koh C.S., Kim B.S. Role of individual T-cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Th1 response. J. Virol. 1998, 72:6169-6174.
    • (1998) J. Virol. , vol.72 , pp. 6169-6174
    • Yauch, R.L.1    Palma, J.P.2    Yahikozawa, H.3    Koh, C.S.4    Kim, B.S.5
  • 55
    • 21244483422 scopus 로고    scopus 로고
    • TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells
    • Zanoni I., Foti M., Ricciardi-Castagnoli P., Granucci F. TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells. J. Immunol. 2005, 175:286-292.
    • (2005) J. Immunol. , vol.175 , pp. 286-292
    • Zanoni, I.1    Foti, M.2    Ricciardi-Castagnoli, P.3    Granucci, F.4
  • 57
    • 49649103793 scopus 로고    scopus 로고
    • Critical role of notch signaling in osteosarcoma invasion and metastasis
    • Zhang P., Yang Y., Zweidler-McKay P.A., Hughes D.P. Critical role of notch signaling in osteosarcoma invasion and metastasis. Clin. Cancer Res. 2008, 14:2962-2969.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 2962-2969
    • Zhang, P.1    Yang, Y.2    Zweidler-McKay, P.A.3    Hughes, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.