-
1
-
-
34548125305
-
Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
-
DOI 10.1038/ni1496, PII NI1496
-
Acosta-Rodriguez EV, Napolitani G, Lanzavecchia A, Sallusto F: Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol, 2007, 8, 942-949 (Pubitemid 47300008).
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
2
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
DOI 10.1074/jbc.M207577200
-
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL: Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem, 2003, 278, 1910-1914 (Pubitemid 36801431).
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.3
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.-H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
3
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, Parente E et al.: Phenotypic and functional features of human Th17 cells. J Exp Med, 2007, 204-1861.
-
(2007)
J Exp Med
, pp. 204-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
-
4
-
-
70349635629
-
All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis
-
Bai A, Lu N, Guo Y, Liu Z, Chen J, Peng Z: All-trans retinoic acid down-regulates inflammatory responses by shifting the Treg/Th17 profile in human ulcerative and murine colitis. J Leukoc Biol, 2009, 86, 959-969.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 959-969
-
-
Bai, A.1
Lu, N.2
Guo, Y.3
Liu, Z.4
Chen, J.5
Peng, Z.6
-
5
-
-
0030970058
-
Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis
-
Benveniste EN: Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis. J Mol Med, 1997, 75, 165-173.
-
(1997)
J Mol Med
, vol.75
, pp. 165-173
-
-
Benveniste, E.N.1
-
6
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK: Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature, 2006, 441, 235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
7
-
-
0033393367
-
Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis
-
DOI 10.1006/cyto.1999.0502
-
Boe A, Baiocchi M, Carbonatto M, Papoian R, Serlupi- Crescenzi O: Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. Cytokine, 1999, 11, 1057-1064 (Pubitemid 30045345).
-
(1999)
Cytokine
, vol.11
, Issue.12
, pp. 1057-1064
-
-
Boe, A.1
Baiocchi, M.2
Carbonatto, M.3
Papoian, R.4
Serlupi-Crescenzi, O.5
-
8
-
-
68149169760
-
Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease
-
Brereton CF, Sutton CE, Lalor SJ, Lavelle EC, Mills KH: Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease. J Immunol, 2009, 183, 1715-1723.
-
(2009)
J Immunol
, vol.183
, pp. 1715-1723
-
-
Brereton, C.F.1
Sutton, C.E.2
Lalor, S.J.3
Lavelle, E.C.4
Mills, K.H.5
-
9
-
-
0036884860
-
Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody
-
Brok HP, van Meurs M, Blezer E, Schantz A, Peritt D, Treacy G, Laman JD et al.: Prevention of experimental autoimmune encephalomyelitis in common marmosets using an anti-IL-12p40 monoclonal antibody. J Immunol, 2002, 169, 6554-6563 (Pubitemid 36903508).
-
(2002)
Journal of Immunology
, vol.169
, Issue.11
, pp. 6554-6563
-
-
Brok, H.P.M.1
Van Meurs, M.2
Blezer, E.3
Schantz, A.4
Peritt, D.5
Treacy, G.6
Laman, J.D.7
Bauer, J.8
'T, H.B.A.9
-
10
-
-
0038558248
-
Dectin-1 mediates the biological effects of β-glucans
-
DOI 10.1084/jem.20021890
-
Brown GD, Herre J, Williams DL, Willment JA, Marshall AS, Gordon S: Dectin-1 mediates the biological effects of β-glucans. J Exp Med, 2003, 197, 1119-1124 (Pubitemid 36570067).
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.9
, pp. 1119-1124
-
-
Brown, G.D.1
Herre, J.2
Williams, D.L.3
Willment, J.A.4
Marshall, A.S.J.5
Gordon, S.6
-
11
-
-
33745553245
-
A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease
-
DOI 10.1097/01.ibd.0000225337.14356.31, PII 0005472520060700000004
-
Burakoff R, Barish CF, Riff D, Pruitt R, Chey WY, Farraye FA, Shafran I et al.: A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease. Inflamm Bowel Dis, 2006, 12, 558-565 (Pubitemid 43977736).
-
(2006)
Inflammatory Bowel Diseases
, vol.12
, Issue.7
, pp. 558-565
-
-
Burakoff, R.1
Barish, C.F.2
Riff, D.3
Pruitt, R.4
Chey, W.Y.5
Farraye, F.A.6
Shafran, I.7
Katz, S.8
Krone, C.L.9
Vander, V.M.10
Stevens, C.11
Sherman, M.L.12
Jacobson, E.13
Bleday, R.14
-
12
-
-
0036188478
-
Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein
-
DOI 10.1002/art.10173
-
Bush KA, Farmer KM, Walker JS, Kirkham BW: Reduction of joint inflammation and bone erosion in rat adjuvant arthritis by treatment with interleukin-17 receptor IgG1 Fc fusion protein. Arthritis Rheum, 2002, 46, 802-805 (Pubitemid 34214263).
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.3
, pp. 802-805
-
-
Bush, K.A.1
Farmer, K.M.2
Walker, J.S.3
Kirkham, B.W.4
-
13
-
-
33845947424
-
Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells
-
Carmody RJ, Ruan Q, Liou HC, Chen YH: Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells. J Immunol, 2007, 178, 186-191 (Pubitemid 46033600).
-
(2007)
Journal of Immunology
, vol.178
, Issue.1
, pp. 186-191
-
-
Carmody, R.J.1
Ruan, Q.2
Liou, H.-C.3
Chen, Y.H.4
-
14
-
-
0031802932
-
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines
-
Chabaud M, Fossiez F, Taupin JL, Miossec P: Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J Immunol, 1998, 161, 409-414 (Pubitemid 28285549).
-
(1998)
Journal of Immunology
, vol.161
, Issue.1
, pp. 409-414
-
-
Chabaud, M.1
Fossiez, F.2
Taupin, J.-L.3
Miossec, P.4
-
15
-
-
0033926254
-
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis
-
DOI 10.1006/cyto.2000.0681
-
Chabaud M, Garnero P, Dayer JM, Guerne PA, Fossiez F, Miossec P: Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis. Cytokine, 2000, 12, 1092-1099 (Pubitemid 30479493).
-
(2000)
Cytokine
, vol.12
, Issue.7
, pp. 1092-1099
-
-
Chabaud, M.1
Garnero, P.2
Dayer, J.-M.3
Guerne, P.-A.4
Fossiez, F.5
Miossec, P.6
-
16
-
-
0037592950
-
Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
-
DOI 10.1074/jbc.M210429200
-
Chen Y, Thai P, Zhao YH, Ho YS, DeSouza MM, Wu R: Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem, 2003, 278, 17036-17043 (Pubitemid 36799579).
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 17036-17043
-
-
Chen, Y.1
Thai, P.2
Zhao, Y.-H.3
Ho, Y.-S.4
DeSouza, M.M.5
Wu, R.6
-
17
-
-
34848821989
-
Distinct regulation of interleukin-17 in human T helper lymphocytes
-
DOI 10.1002/art.22866
-
Chen Z, Tato CM, Muul L, Laurence A, O'Shea JJ: Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum, 2007, 56, 2936-2946 (Pubitemid 47502740).
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.9
, pp. 2936-2946
-
-
Chen, Z.1
Tato, C.M.2
Muul, L.3
Laurence, A.4
O'Shea, J.J.5
-
18
-
-
0036190776
-
Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin-1 receptor antagonist, in combination with methotrexate: Results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial
-
DOI 10.1002/art.10141
-
Cohen S, Hurd E, Cush J, Schiff M, Weinblatt ME, Moreland LW, Kremer J et al.: Treatment of rheumatoid arthritis with anakinra, a recombinant human interleukin- 1 receptor antagonist, in combination with methotrexate: results of a twenty-four-week, multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum, 2002, 46, 614-624 (Pubitemid 34214243).
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.3
, pp. 614-624
-
-
Cohen, S.1
Hurd, E.2
Cush, J.3
Schiff, M.4
Weinblatt, M.E.5
Moreland, L.W.6
Kremer, J.7
Bear, M.B.8
Rich, W.J.9
McCabe, D.10
-
19
-
-
2542486456
-
Asthma: Mechanisms of disease persistence and progression
-
DOI 10.1146/annurev.immunol.22.012703.104716
-
Cohn L, Elias JA, Chupp GL: Asthma: mechanisms of disease persistence and progression. Annu Rev Immunol, 2004, 22, 789-815 (Pubitemid 38680442).
-
(2004)
Annual Review of Immunology
, vol.22
, pp. 789-815
-
-
Cohn, L.1
Elias, J.A.2
Chupp, G.L.3
-
20
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
DOI 10.1038/nature01355
-
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L et al.: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature, 2003, 421, 744-748 (Pubitemid 36227625)
-
(2003)
Nature
, vol.421
, Issue.6924
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
21
-
-
59849109226
-
Vaccination of mice against H. pylori induces a strong Th-17 response and immunity that is neutrophil dependent
-
DeLyria ES, Redline RW, Blanchard TG: Vaccination of mice against H. pylori induces a strong Th-17 response and immunity that is neutrophil dependent. Gastroenterology, 2009, 136, 247-256.
-
(2009)
Gastroenterology
, vol.136
, pp. 247-256
-
-
DeLyria, E.S.1
Redline, R.W.2
Blanchard, T.G.3
-
22
-
-
47949090745
-
Development of proteoglycan-induced arthritis is independent of IL-17
-
Doodes PD, Cao Y, Hamel KM, Wang Y, Farkas B, Iwakura Y, Finnegan A: Development of proteoglycan-induced arthritis is independent of IL-17. J Immunol, 2008, 181, 329-337.
-
(2008)
J Immunol
, vol.181
, pp. 329-337
-
-
Doodes, P.D.1
Cao, Y.2
Hamel, K.M.3
Wang, Y.4
Farkas, B.5
Iwakura, Y.6
Finnegan, A.7
-
23
-
-
36749081557
-
Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes
-
DOI 10.1073/pnas.0708426104
-
Evans HG, Suddason T, Jackson I, Taams LS, Lord GM: Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes. Proc Natl Acad Sci USA, 2007, 104, 17034-17039 (Pubitemid 350210986).
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.43
, pp. 17034-17039
-
-
Evans, H.G.1
Suddason, T.2
Jackson, I.3
Taams, L.S.4
Lord, G.M.5
-
24
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
DOI 10.1084/jem.183.6.2593
-
Fossiez F, Djossou O, Chomarat P, Flores-Romo L, Ait-Yahia S, Maat C, Pin JJ et al.: T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med, 1996, 183, 2593-2603 (Pubitemid 26193037).
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.6
, pp. 2593-2603
-
-
Fossiez, F.1
Djossou, O.2
Chomarat, P.3
Flores-Romo, L.4
Ait-Yahia, S.5
Maat, C.6
Pin, J.-J.7
Garrone, P.8
Garcia, E.9
Saeland, S.10
Blanchard, D.11
Gaillard, C.12
Das, M.B.13
Rouvier, E.14
Golstein, P.15
Banchereau, J.16
Lebecque, S.17
-
25
-
-
0038558249
-
Collaborative induction of inflammatory responses by dectin-1 and toll-like receptor 2
-
DOI 10.1084/jem.20021787
-
Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM: Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med, 2003, 197, 1107-1117 (Pubitemid 36570066).
-
(2003)
Journal of Experimental Medicine
, vol.197
, Issue.9
, pp. 1107-1117
-
-
Gantner, B.N.1
Simmons, R.M.2
Canavera, S.J.3
Akira, S.4
Underhill, D.M.5
-
26
-
-
45149118823
-
Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells
-
DOI 10.1084/jem.20071450
-
Gerosa F, Baldani-Guerra B, Lyakh LA, Batoni G, Esin S, Winkler-Pickett RT, Consolaro MR et al.: Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells. J Exp Med, 2008, 205, 1447-1461 (Pubitemid 351831499).
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.6
, pp. 1447-1461
-
-
Gerosa, F.1
Baldani-Guerra, B.2
Lyakh, L.A.3
Batoni, G.4
Esin, S.5
Winkler-Pickett, R.T.6
Consolaro, M.R.7
De Marchi, M.8
Giachino, D.9
Robbiano, A.10
Astegiano, M.11
Sambataro, A.12
Kastelein, R.A.13
Carra, G.14
Trinchieri, G.15
-
27
-
-
0036795111
-
Analysis of induced sputum in adults with asthma: Identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
-
DOI 10.1136/thorax.57.10.875
-
Green RH, Brightling CE, Woltmann G, Parker D, Wardlaw AJ, Pavord ID: Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids. Thorax, 2002, 57, 875-879 (Pubitemid 35178612).
-
(2002)
Thorax
, vol.57
, Issue.10
, pp. 875-879
-
-
Green, R.H.1
Brightling, C.E.2
Woltmann, G.3
Parker, D.4
Wardlaw, A.J.5
Pavord, I.D.6
-
28
-
-
27544490377
-
+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
DOI 10.1038/ni1254, PII N1254
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol, 2005, 6, 1123-1132 (Pubitemid 41541790).
-
(2005)
Nature Immunology
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
29
-
-
33750815930
-
+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses
-
He D, Wu L, Kim HK, Li H, Elmets CA, Xu H: CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol, 2006, 177, 6852-6858 (Pubitemid 44715050).
-
(2006)
Journal of Immunology
, vol.177
, Issue.10
, pp. 6852-6858
-
-
He, D.1
Wu, L.2
Kim, H.K.3
Li, H.4
Elmets, C.A.5
Xu, H.6
-
30
-
-
70249096341
-
IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses
-
He D, Wu L, Kim HK, Li H, Elmets CA, Xu H: IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses. J Immunol, 2009, 183, 1463-1470.
-
(2009)
J Immunol
, vol.183
, pp. 1463-1470
-
-
He, D.1
Wu, L.2
Kim, H.K.3
Li, H.4
Elmets, C.A.5
Xu, H.6
-
31
-
-
0142105932
-
Progesterone increases airway eosinophilia and hyper-responsiveness in a murine model of allergic asthma
-
DOI 10.1046/j.1365-2222.2003.01743.x
-
Hellings PW, Vandekerckhove P, Claeys R, Billen J, Kasran A, Ceuppens JL: Progesterone increases airway eosinophilia and hyper-responsiveness in a murine model of allergic asthma. Clin Exp Allergy, 2003, 33, 1457-1463 (Pubitemid 37289945).
-
(2003)
Clinical and Experimental Allergy
, vol.33
, Issue.10
, pp. 1457-1463
-
-
Hellings, P.W.1
Vandekerckhove, P.2
Claeys, R.3
Billen, J.4
Kasran, A.5
Ceuppens, J.L.6
-
32
-
-
33751579426
-
TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: Role of IL-17-producing T cells
-
Higgins SC, Jarnicki AG, Lavelle EC, Mills KH: TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells. J Immunol, 2006, 177, 7980-7989 (Pubitemid 44846315).
-
(2006)
Journal of Immunology
, vol.177
, Issue.11
, pp. 7980-7989
-
-
Higgins, S.C.1
Jarnicki, A.G.2
Lavelle, E.C.3
Mills, K.H.G.4
-
33
-
-
70149106667
-
Type 17 CD8+ T cells display enhanced antitumor immunity
-
Hinrichs CS, Kaiser A, Paulos CM, Cassard L, Sanchez-Perez L, Heemskerk B, Wrzesinski C, Borman ZA et al.: Type 17 CD8+ T cells display enhanced antitumor immunity. Blood, 2009, 114, 596-599.
-
(2009)
Blood
, vol.114
, pp. 596-599
-
-
Hinrichs, C.S.1
Kaiser, A.2
Paulos, C.M.3
Cassard, L.4
Sanchez-Perez, L.5
Heemskerk, B.6
Wrzesinski, C.7
Borman, Z.A.8
-
34
-
-
30944452780
-
Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis
-
DOI 10.1016/j.cellimm.2005.11.002, PII S000887490500242X
-
Hofstetter HH, Ibrahim SM, Koczan D, Kruse N, Weishaupt A, Toyka KV, Gold R: Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol, 2005, 237, 123-130 (Pubitemid 43117208).
-
(2005)
Cellular Immunology
, vol.237
, Issue.2
, pp. 123-130
-
-
Hofstetter, H.H.1
Ibrahim, S.M.2
Koczan, D.3
Kruse, N.4
Weishaupt, A.5
Toyka, K.V.6
Gold, R.7
-
35
-
-
0033564323
-
IL-12, independently of IFN-γ, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder
-
Hong K, Chu A, Ludviksson BR, Berg EL, Ehrhardt RO: IL-12, independently of IFN-γ, plays a crucial role in the pathogenesis of a murine psoriasis-like skin disorder. J Immunol, 1999, 162, 7480-7491 (Pubitemid 29277728).
-
(1999)
Journal of Immunology
, vol.162
, Issue.12
, pp. 7480-7491
-
-
Hong, K.1
Chu, A.2
Ludviksson, B.R.3
Berg, E.L.4
Ehrhardt, R.O.5
-
36
-
-
69249092613
-
+ Tc17 cells with reduced cytotoxic activity
-
+ Tc17 cells with reduced cytotoxic activity. Eur J Immunol, 2009, 39, 1716-1725.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1716-1725
-
-
Huber, M.1
Heink, S.2
Grothe, H.3
Guralnik, A.4
Reinhard, K.5
Elflein, K.6
Hunig, T.7
-
37
-
-
17944368518
-
IL-17s adopt a cystine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
-
Hymowitz SG, Filvaroff EH, Yin JP, Lee J, Cai L, Risser P, Maruoka M et al.: IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J, 2001, 20, 5332-5341.
-
(2001)
EMBO J
, vol.20
, pp. 5332-5341
-
-
Hymowitz, S.G.1
Filvaroff, E.H.2
Yin, J.P.3
Lee, J.4
Cai, L.5
Risser, P.6
Maruoka, M.7
-
38
-
-
0034541221
-
Microbial lipopeptides induce the production of IL-17 in Th cells
-
Infante-Duarte C, Horton HF, Byrne MC, Kamradt T: Microbial lipopeptides induce the production of IL-17 in Th cells. J Immunol, 2000, 165, 6107-6115.
-
(2000)
J Immunol
, vol.165
, pp. 6107-6115
-
-
Infante-Duarte, C.1
Horton, H.F.2
Byrne, M.C.3
Kamradt, T.4
-
39
-
-
68049097199
-
Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis
-
Ito Y, Usui T, Kobayashi S, Iguchi-Hashimoto M, Ito H, Yoshitomi H, Nakamura T et al.: Gamma/delta T cells are the predominant source of interleukin-17 in affected joints in collagen-induced arthritis, but not in rheumatoid arthritis. Arthritis Rheum, 2009, 60, 2294-2303.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2294-2303
-
-
Ito, Y.1
Usui, T.2
Kobayashi, S.3
Iguchi-Hashimoto, M.4
Ito, H.5
Yoshitomi, H.6
Nakamura, T.7
-
40
-
-
33748588423
-
+ T Helper Cells
-
DOI 10.1016/j.cell.2006.07.035, PII S0092867406011056
-
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR: The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell, 2006, 126, 1121-1133 (Pubitemid 44380299).
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
41
-
-
70350052626
-
H17 cells in multiple sclerosis
-
H17 cells in multiple sclerosis. Ann Neurol, 2009, 66, 390-402.
-
(2009)
Ann Neurol
, vol.66
, pp. 390-402
-
-
Kebir, H.1
Ifergan, I.2
Alvarez, J.I.3
Bernard, M.4
Poirier, J.5
Arbour, N.6
Duquette, P.7
Prat, A.8
-
42
-
-
34248562792
-
+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
-
DOI 10.1038/ni1449, PII NI1449
-
Khader SA, Bell GK, Pearl JE, Fountain JJ, Rangel- Moreno J, Cilley GE, Shen F et al.: IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol, 2007, 8, 369-377 (Pubitemid 46745412).
-
(2007)
Nature Immunology
, vol.8
, Issue.4
, pp. 369-377
-
-
Khader, S.A.1
Bell, G.K.2
Pearl, J.E.3
Fountain, J.J.4
Rangel-Moreno, J.5
Cilley, G.E.6
Shen, F.7
Eaton, S.M.8
Gaffen, S.L.9
Swain, S.L.10
Locksley, R.M.11
Haynes, L.12
Randall, T.D.13
Cooper, A.M.14
-
43
-
-
39649108216
-
Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: Results of a randomized, placebo-controlled, phase 2 trial
-
DOI 10.1001/archdermatol.2007.63
-
Kimball AB, Gordon KB, Langley RG, Menter A, Chartash EK, Valdes J: Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial. Arch Dermatol, 2008, 144, 200-207 (Pubitemid 351287002).
-
(2008)
Archives of Dermatology
, vol.144
, Issue.2
, pp. 200-207
-
-
Kimball, A.B.1
Gordon, K.B.2
Langley, R.G.3
Menter, A.4
Chartash, E.K.5
Valdes, J.6
-
44
-
-
34547514211
-
IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells
-
DOI 10.1073/pnas.0705268104
-
Kimura A, Naka T, Kishimoto T: IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells. Proc Natl Acad Sci USA, 2007, 104, 12099-12104 (Pubitemid 47185636).
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.29
, pp. 12099-12104
-
-
Kimura, A.1
Naka, T.2
Kishimoto, T.3
-
45
-
-
67049137416
-
Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis
-
Klemann C, Raveney BJ, Klemann AK, Ozawa T, von Horsten S, Shudo K, Oki S, Yamamura T: Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis. Am J Pathol, 2009, 174, 2234-2245.
-
(2009)
Am J Pathol
, vol.174
, pp. 2234-2245
-
-
Klemann, C.1
Raveney, B.J.2
Klemann, A.K.3
Ozawa, T.4
Von Horsten, S.5
Shudo, K.6
Oki, S.7
Yamamura, T.8
-
46
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
DOI 10.1016/j.immuni.2004.08.018, PII S1074761304002717
-
Kolls JK, Linden A: Interleukin-17 family members and inflammation. Immunity, 2004, 21, 467-476 (Pubitemid 39370503).
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 467-476
-
-
Kolls, J.K.1
Linden, A.2
-
47
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama Y, Nakae S, Matsuki T, Nambu A, Ishigame H, Kakuta S, Sudo K, Iwakura Y: IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol, 2006, 177, 566-573 (Pubitemid 43939170).
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
Nambu, A.4
Ishigame, H.5
Kakuta, S.6
Sudo, K.7
Iwakura, Y.8
-
49
-
-
34547232503
-
H17 cells
-
H17 cells. Nature, 2007, 448, 484-487.
-
(2007)
Nature
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jager, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
50
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake S, Udagawa N, Takahashi N, Matsuzaki K, Itoh K, Ishiyama S, Saito S et al.: IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest, 1999, 103, 1345-1352 (Pubitemid 29218305).
-
(1999)
Journal of Clinical Investigation
, vol.103
, Issue.9
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
51
-
-
46949104323
-
IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
DOI 10.1084/jem.20080159
-
Kroenke MA, Carlson TJ, Andjelkovic AV, Segal BM: IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J Exp Med, 2008, 205, 1535-1541 (Pubitemid 351962016).
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.7
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
52
-
-
34249806717
-
Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment
-
Kryczek I, Wei S, Zou L, Altuwaijri S, Szeliga W, Kolls J, Chang A, Zou W: Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. J Immunol, 2007, 178, 6730-6733 (Pubitemid 46847396).
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 6730-6733
-
-
Kryczek, I.1
Wei, S.2
Zou, L.3
Altuwaijri, S.4
Szeliga, W.5
Kolls, J.6
Chang, A.7
Zou, W.8
-
53
-
-
52049119316
-
Pleiotropic effects of angiotensin- converting enzyme inhibitors in normotensive patients with coronary artery disease
-
Krysiak R, Okopień B: Pleiotropic effects of angiotensin- converting enzyme inhibitors in normotensive patients with coronary artery disease. Pharmacol Rep, 2008, 60, 514-523.
-
(2008)
Pharmacol Rep
, vol.60
, pp. 514-523
-
-
Krysiak, R.1
Okopień, B.2
-
54
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T et al.: IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med, 2005, 201, 233-240 (Pubitemid 40189432).
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
55
-
-
34249026701
-
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
DOI 10.1038/ni1460, PII NI1460
-
LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E et al.: Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol, 2007, 8, 630-638 (Pubitemid 46785127).
-
(2007)
Nature Immunology
, vol.8
, Issue.6
, pp. 630-638
-
-
LeibundGut-Landmann, S.1
Gross, O.2
Robinson, M.J.3
Osorio, F.4
Slack, E.C.5
Tsoni, S.V.6
Schweighoffer, E.7
Tybulewicz, V.8
Brown, G.D.9
Ruland, J.10
Reis, E.S.C.11
-
56
-
-
33644751206
-
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts
-
DOI 10.1016/j.jaci.2005.10.025, PII S0091674905023195
-
Letuve S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q: IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J Allergy Clin Immunol, 2006, 117, 590-596 (Pubitemid 43340223).
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.3
, pp. 590-596
-
-
Letuve, S.1
Lajoie-Kadoch, S.2
Audusseau, S.3
Rothenberg, M.E.4
Fiset, P.-O.5
Ludwig, M.S.6
Hamid, Q.7
-
57
-
-
0034681131
-
Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family
-
DOI 10.1073/pnas.97.2.773
-
Li H, Chen J, Huang A, Stinson J, Heldens S, Foster J, Dowd P et al.: Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family. Proc Natl Acad Sci USA, 2000, 97, 773-778 (Pubitemid 30070385).
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.2
, pp. 773-778
-
-
Li, H.1
Chen, J.2
Huang, A.3
Stinson, J.4
Heldens, S.5
Foster, J.6
Dowd, P.7
Gurney, A.L.8
Wood, W.I.9
-
58
-
-
77949654682
-
Th17 cytokines and vaccine-induced immunity
-
Lin Y, Slight SR, Khader SA: Th17 cytokines and vaccine-induced immunity. Semin Immunopathol, 2010, 32, 79-90.
-
(2010)
Semin Immunopathol
, vol.32
, pp. 79-90
-
-
Lin, Y.1
Slight, S.R.2
Khader, S.A.3
-
59
-
-
34547769911
-
Induction of a distinct CD8 Tnc17 subset by transforming growth factor-β and interleukin-6
-
Liu SJ, Tsai JP, Shen CR, Sher YP, Hsieh CL, Yeh YC, Chou AH et al.: Induction of a distinct CD8 Tnc17 subset by transforming growth factor-β and interleukin-6. J Leukoc Biol, 2007, 82, 354-360.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 354-360
-
-
Liu, S.J.1
Tsai, J.P.2
Shen, C.R.3
Sher, Y.P.4
Hsieh, C.L.5
Yeh, Y.C.6
Chou, A.H.7
-
60
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
DOI 10.1038/nm0502-500
-
Lock C, Hermans G, Pedotti R, Brendolan A, Schadt E, Garren H, Langer-Gould A et al.: Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat Med, 2002, 8, 500-508 (Pubitemid 34546753).
-
(2002)
Nature Medicine
, vol.8
, Issue.5
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
Brendolan, A.4
Schadt, E.5
Garren, H.6
Langer-Gould, A.7
Strober, S.8
Cannella, B.9
Allard, J.10
Klonowski, P.11
Austin, A.12
Lad, N.13
Kaminski, N.14
Galli, S.J.15
Oksenberg, J.R.16
Raine, C.S.17
Heller, R.18
Steinman, L.19
-
61
-
-
53049107872
-
Interleukin-17A mediates acquired immunity to pneumococcal colonization
-
Lu YJ, Gross J, Bogaert D, Finn A, Bagrade L, Zhang Q, Kolls JK et al.: Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog, 2008, 4, e1000159.
-
(2008)
PLoS Pathog
, vol.4
-
-
Lu, Y.J.1
Gross, J.2
Bogaert, D.3
Finn, A.4
Bagrade, L.5
Zhang, Q.6
Kolls, J.K.7
-
62
-
-
1042267236
-
Treatment with a Neutralizing Anti-Murine Interleukin-17 Antibody after the Onset of Collagen-Induced Arthritis Reduces Joint Inflammation, Cartilage Destruction, and Bone Erosion
-
DOI 10.1002/art.20001
-
Lubberts E, Koenders MI, Oppers-Walgreen B, van den Bersselaar L, Coenen-de Roo CJ, Joosten LA, van den Berg WB: Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum, 2004, 50, 650-659 (Pubitemid 38198849).
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.2
, pp. 650-659
-
-
Lubberts, E.1
Koenders, M.I.2
Oppers-Walgreen, B.3
Van Den, B.L.4
Coenen-De, R.C.J.J.5
Joosten, L.A.B.6
Van Den, B.W.B.7
-
63
-
-
67651165149
-
Role of TLR ligands in epicutaneously induced contrasuppression
-
Majewska M, Bryniarski K, Ptak M, Zaja̧c K, Zemelka M, Lobo FM, Ptak W, Szczepanik M: Role of TLR ligands in epicutaneously induced contrasuppression. Pharmacol Rep, 2009, 61, 539-549.
-
(2009)
Pharmacol Rep
, vol.61
, pp. 539-549
-
-
Majewska, M.1
Bryniarski, K.2
Ptak, M.3
Zaja̧c, K.4
Zemelka, M.5
Lobo, F.M.6
Ptak, W.7
Szczepanik, M.8
-
64
-
-
44049104564
-
H-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
-
DOI 10.1038/ni.1610, PII NI.1610
-
Manel N, Unutmaz D, Littman DR: The differentiation of human TH-17 cells requires transforming growth factor- β and induction of the nuclear receptor RORγt. Nat Immunol, 2008, 9, 641-649 (Pubitemid 351714729).
-
(2008)
Nature Immunology
, vol.9
, Issue.6
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
65
-
-
33646560950
-
H17 lineage
-
H17 lineage. Nature, 2006, 441, 231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
-
66
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
DOI 10.1056/NEJMoa033402
-
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B et al.: Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med, 2004, 351, 2069-2079 (Pubitemid 39482500).
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.20
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
Dolin, B.7
Goodman, N.8
Groden, C.9
Hornung, R.L.10
Quezado, M.11
Neurath, M.F.12
Salfeld, J.13
Veldman, G.M.14
Schwertschlag, U.15
Strober, W.16
-
67
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N, Muranski P, Chung Y, Yang XO, Yamazaki T, Lu S, Hwu P et al.: T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity, 2009, 31, 787-798.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
Yang, X.O.4
Yamazaki, T.5
Lu, S.6
Hwu, P.7
-
68
-
-
68649126866
-
Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals
-
Martin B, Hirota K, Cua DJ, Stockinger B, Veldhoen M: Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals. Immunity, 2009, 31, 321-330.
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
Stockinger, B.4
Veldhoen, M.5
-
69
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius D, Kivisakk P, He B, Kostulas N, Ozenci V, Fredrikson S, Link H: Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler, 1999, 5, 101-104 (Pubitemid 29186827).
-
(1999)
Multiple Sclerosis
, vol.5
, Issue.2
, pp. 101-104
-
-
Matusevicius, D.1
Kivisakk, P.2
He, B.3
Kostulas, N.4
Ozenci, V.5
Fredrikson, S.6
Link, H.7
-
70
-
-
21244455537
-
Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-α and granulocyte colony-stimulating factor in bronchial epithelium: Implications for airway inflammation in cystic fibrosis
-
McAllister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C, Finder JD et al.: Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene- α and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol, 2005, 175, 404-412 (Pubitemid 40884344).
-
(2005)
Journal of Immunology
, vol.175
, Issue.1
, pp. 404-412
-
-
McAllister, F.1
Henry, A.2
Kreindler, J.L.3
Dubin, P.J.4
Ulrich, L.5
Steele, C.6
Finder, J.D.7
Pilewski, J.M.8
Carreno, B.M.9
Goldman, S.J.10
Pirhonen, J.11
Kolls, J.K.12
-
71
-
-
36248965294
-
H-17 cell-mediated pathology
-
H-17 cell-mediated pathology. Nat Immunol, 2007, 8, 1390-1397.
-
(2007)
Nat Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
Cua, D.J.7
-
72
-
-
0034833339
-
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
-
DOI 10.1067/mai.2001.117929
-
Molet S, Hamid Q, Davoine F, Nutku E, Taha R, Page N, Olivenstein R et al.: IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol, 2001, 108, 430-438 (Pubitemid 32881066).
-
(2001)
Journal of Allergy and Clinical Immunology
, vol.108
, Issue.3
, pp. 430-438
-
-
Molet, S.1
Hamid, Q.2
Davoine, F.3
Nutku, E.4
Taha, R.5
Page, N.6
Olivenstein, R.7
Elias, J.8
Chakir, J.9
-
73
-
-
34447503805
-
H17 and regulatory T cell differentiation mediated by retinoic acid
-
DOI 10.1126/science.1145697
-
Mucida D, Park Y, Kim G, Turovskaya O, Scott I, Kronenberg M, Cheroutre H: Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science, 2007, 317, 256-260 (Pubitemid 47076203).
-
(2007)
Science
, vol.317
, Issue.5835
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
Cheroutre, H.7
-
74
-
-
0036754255
-
Antigen-specific T cell sensitization is impaired in Il-17-deficient mice, causing suppression of allergic cellular and humoral responses
-
DOI 10.1016/S1074-7613(02)00391-6
-
Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I, Sekikawa K et al.: Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity, 2002, 17, 375-387 (Pubitemid 35279557).
-
(2002)
Immunity
, vol.17
, Issue.3
, pp. 375-387
-
-
Nakae, S.1
Komiyama, Y.2
Nambu, A.3
Sudo, K.4
Iwase, M.5
Homma, I.6
Sekikawa, K.7
Asano, M.8
Iwakura, Y.9
-
75
-
-
0344585384
-
Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice
-
Nakae S, Nambu A, Sudo K, Iwakura Y: Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol, 2003, 171, 6173-6177 (Pubitemid 37467240).
-
(2003)
Journal of Immunology
, vol.171
, Issue.11
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
76
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W: Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med, 1995, 182, 1281-1290.
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
77
-
-
0037849915
-
Interleukin-17 promotes angiogenesis and tumor growth
-
DOI 10.1182/blood-2002-05-1461
-
Numasaki M, Fukushi J, Ono M, Narula SK, Zavodny PJ, Kudo T, Robbins PD et al.: Interleukin-17 promotes angiogenesis and tumor growth. Blood, 2003, 101, 2620-2627 (Pubitemid 36857622).
-
(2003)
Blood
, vol.101
, Issue.7
, pp. 2620-2627
-
-
Numasaki, M.1
Fukushi, J.-I.2
Ono, M.3
Narula, S.K.4
Zavodny, P.J.5
Kudo, T.6
Robbins, P.D.7
Tahara, H.8
Lotze, M.T.9
-
78
-
-
2342468719
-
Interleukin-17 augments tumor necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts
-
DOI 10.1016/j.imlet.2004.01.014, PII S016524780400015X
-
Numasaki M, Lotze MT, Sasaki H: Interleukin-17 augments tumor necrosis factor-α-induced elaboration of proangiogenic factors from fibroblasts. Immunol Lett, 2004, 93, 39-43 (Pubitemid 38591518).
-
(2004)
Immunology Letters
, vol.93
, Issue.1
, pp. 39-43
-
-
Numasaki, M.1
Lotze, M.T.2
Sasaki, H.3
-
79
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
-
O'Connor W, Jr., Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA: A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol, 2009, 10, 603-609.
-
(2009)
Nat Immunol
, vol.10
, pp. 603-609
-
-
O'Connor Jr., W.1
Kamanaka, M.2
Booth, C.J.3
Town, T.4
Nakae, S.5
Iwakura, Y.6
Kolls, J.K.7
Flavell, R.A.8
-
80
-
-
43449139402
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
DOI 10.1016/S0140-6736(08)60726-6, PII S0140673608607266
-
Papp KA, Langley RG, Lebwohl M, Krueger GG, Szapary P, Yeilding N, Guzzo C et al.: Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet, 2008, 371, 1675-1684 (Pubitemid 351671884).
-
(2008)
The Lancet
, vol.371
, Issue.9625
, pp. 1675-1684
-
-
Papp, K.A.1
Langley, R.G.2
Lebwohl, M.3
Krueger, G.G.4
Szapary, P.5
Yeilding, N.6
Guzzo, C.7
Hsu, M.-C.8
Wang, Y.9
Li, S.10
Dooley, L.T.11
Reich, K.12
-
81
-
-
31144441631
-
In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: Enhanced expression in psoriatic skin
-
Piskin G, Sylva-Steenland RM, Bos JD, Teunissen MB: In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin. J Immunol, 2006, 176, 1908-1915.
-
(2006)
J Immunol
, vol.176
, pp. 1908-1915
-
-
Piskin, G.1
Sylva-Steenland, R.M.2
Bos, J.D.3
Teunissen, M.B.4
-
82
-
-
70349267599
-
Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity
-
Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK et al.: Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proc Natl Acad Sci USA, 2009, 106, 14948-14953.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14948-14953
-
-
Platten, M.1
Youssef, S.2
Hur, E.M.3
Ho, P.P.4
Han, M.H.5
Lanz, T.V.6
Phillips, L.K.7
-
83
-
-
42649110747
-
Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
-
Rachitskaya AV, Hansen AM, Horai R, Li Z, Villasmil R, Luger D, Nussenblatt RB, Caspi RR: Cutting edge: NKT cells constitutively express IL-23 receptor and RORγt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J Immunol, 2008, 180, 5167-5171.
-
(2008)
J Immunol
, vol.180
, pp. 5167-5171
-
-
Rachitskaya, A.V.1
Hansen, A.M.2
Horai, R.3
Li, Z.4
Villasmil, R.5
Luger, D.6
Nussenblatt, R.B.7
Caspi, R.R.8
-
84
-
-
38449093216
-
Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing γδ T cells
-
Roark CL, French JD, Taylor MA, Bendele AM, Born WK, O'Brien RL: Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing γδ T cells. J Immunol, 2007, 179, 5576-5583.
-
(2007)
J Immunol
, vol.179
, pp. 5576-5583
-
-
Roark, C.L.1
French, J.D.2
Taylor, M.A.3
Bendele, A.M.4
Born, W.K.5
O'Brien, R.L.6
-
85
-
-
33645064822
-
Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv
-
Romano M, D'Souza S, Adnet PY, Laali R, Jurion F, Palfliet K, Huygen K: Priming but not boosting with plasmid DNA encoding mycolyl-transferase Ag85A from Mycobacterium tuberculosis increases the survival time of Mycobacterium bovis BCG vaccinated mice against low dose intravenous challenge with M. tuberculosis H37Rv. Vaccine, 2006, 24, 3353-3364.
-
(2006)
Vaccine
, vol.24
, pp. 3353-3364
-
-
Romano, M.1
D'Souza, S.2
Adnet, P.Y.3
Laali, R.4
Jurion, F.5
Palfliet, K.6
Huygen, K.7
-
86
-
-
0032534730
-
IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: Roles of IL-6 in the activation and differentiation of autoreactive T cells
-
Samoilova EB, Horton JL, Hilliard B, Liu TS, Chen Y: IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J Immunol, 1998, 161, 6480-6486 (Pubitemid 28562184).
-
(1998)
Journal of Immunology
, vol.161
, Issue.12
, pp. 6480-6486
-
-
Samoilova, E.B.1
Horton, J.L.2
Hilliard, B.3
Liu, T.-S.T.4
Chen, Y.5
-
87
-
-
0033748023
-
Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages
-
Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST: Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proc Natl Acad Sci USA, 2000, 97, 12705-12710.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12705-12710
-
-
Sanjabi, S.1
Hoffmann, A.2
Liou, H.C.3
Baltimore, D.4
Smale, S.T.5
-
88
-
-
48849087125
-
Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A phase II, double-blind, placebo-controlled, randomised, dose-ranging study
-
Segal BM, Constantinescu CS, Raychaudhuri A, Kim L, Fidelus-Gort R, Kasper LH: Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol, 2008, 7, 796-804.
-
(2008)
Lancet Neurol
, vol.7
, pp. 796-804
-
-
Segal, B.M.1
Constantinescu, C.S.2
Raychaudhuri, A.3
Kim, L.4
Fidelus-Gort, R.5
Kasper, L.H.6
-
89
-
-
58149190437
-
Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells
-
Shi G, Cox CA, Vistica BP, Tan C, Wawrousek EF, Gery I: Phenotype switching by inflammation-inducing polarized Th17 cells, but not by Th1 cells. J Immunol, 2008, 181, 7205-7213.
-
(2008)
J Immunol
, vol.181
, pp. 7205-7213
-
-
Shi, G.1
Cox, C.A.2
Vistica, B.P.3
Tan, C.4
Wawrousek, E.F.5
Gery, I.6
-
90
-
-
0032442795
-
+ T cells by cyclic AMP-dependent signal transduction pathway
-
+ T cells by cyclic AMP-dependent signal transduction pathway. Cytokine, 1998, 10, 841-850.
-
(1998)
Cytokine
, vol.10
, pp. 841-850
-
-
Shin, H.C.1
Benbernou, N.2
Fekkar, H.3
Esnault, S.4
Guenounou, M.5
-
91
-
-
34250659752
-
Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan
-
DOI 10.1002/eji.200636830
-
Slack EC, Robinson MJ, Hernanz-Falcon P, Brown GD, Williams DL, Schweighoffer E, Tybulewicz VL, Reis e Sousa C: Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan. Eur J Immunol, 2007, 37, 1600-1612 (Pubitemid 46939495).
-
(2007)
European Journal of Immunology
, vol.37
, Issue.6
, pp. 1600-1612
-
-
Slack, E.C.1
Robinson, M.J.2
Hernanz-Falcon, P.3
Brown, G.D.4
Williams, D.L.5
Schweighoffer, E.6
Tybulewicz, V.L.7
Reis, E.S.C.8
-
92
-
-
40749114497
-
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
-
DOI 10.1016/S0140-6736(08)60453-5, PII S0140673608604535
-
Smolen JS, Beaulieu A, Rubbert-Roth A, Ramos-Remus C, Rovensky J, Alecock E, Woodworth T, Alten R: Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet, 2008, 371, 987-997 (Pubitemid 351392039).
-
(2008)
The Lancet
, vol.371
, Issue.9617
, pp. 987-997
-
-
Smolen, J.S.1
Beaulieu, A.2
Rubbert-Roth, A.3
Ramos-Remus, C.4
Rovensky, J.5
Alecock, E.6
Woodworth, T.7
Alten, R.8
-
93
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity
-
Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH: Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity. Immunity, 2009, 31, 331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.6
-
94
-
-
12444341944
-
Toll-like receptors in innate immunity
-
Takeda K, Akira S: Toll-like receptors in innate immunity. Int Immunol, 2005, 17, 1-14.
-
(2005)
Int Immunol
, vol.17
, pp. 1-14
-
-
Takeda, K.1
Akira, S.2
-
95
-
-
34247586615
-
Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signature and is driven by unique effector mechanisms: Initial encounter with autoantigen defines disease phenotype
-
Tang J, Zhu W, Silver PB, Su SB, Chan CC, Caspi RR: Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signature and is driven by unique effector mechanisms: initial encounter with autoantigen defines disease phenotype. J Immunol, 2007, 178, 5578-5587 (Pubitemid 46674353).
-
(2007)
Journal of Immunology
, vol.178
, Issue.9
, pp. 5578-5587
-
-
Tang, J.1
Zhu, W.2
Silver, P.B.3
Su, S.-B.4
Chan, C.-C.5
Caspi, R.R.6
-
96
-
-
0031691282
-
Interleukin-17 and interferon-γ synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
-
DOI 10.1046/j.1523-1747.1998.00347.x
-
Teunissen MB, Koomen CW, de Waal Malefyt R, Wierenga EA, Bos JD: Interleukin-17 and interferon-γ synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol, 1998, 111, 645-649 (Pubitemid 28452327).
-
(1998)
Journal of Investigative Dermatology
, vol.111
, Issue.4
, pp. 645-649
-
-
Teunissen, M.B.M.1
Koomen, C.W.2
De Waal, M.R.3
Wierenga, E.A.4
Bos, J.D.5
-
97
-
-
33745297345
-
Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
-
Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, Tocker J, Peschon J: Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J Immunol, 2006, 177, 36-39 (Pubitemid 43939112).
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 36-39
-
-
Toy, D.1
Kugler, D.2
Wolfson, M.3
Vanden, B.T.4
Gurgel, J.5
Derry, J.6
Tocker, J.7
Peschon, J.8
-
98
-
-
67651171182
-
H2 cells
-
H2 cells. Nat Immunol, 2009, 10, 864-871.
-
(2009)
Nat Immunol
, Issue.10
, pp. 864-871
-
-
Trifari, S.1
Kaplan, C.D.2
Tran, E.H.3
Crellin, N.K.4
Spits, H.5
-
99
-
-
33744936550
-
IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
-
Vaknin-Dembinsky A, Balashov K, Weiner HL: IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J Immunol, 2006, 176, 7768-7774 (Pubitemid 43849078).
-
(2006)
Journal of Immunology
, vol.176
, Issue.12
, pp. 7768-7774
-
-
Vaknin-Dembinsky, A.1
Balashov, K.2
Weiner, H.L.3
-
100
-
-
42649106556
-
H17-cell-mediated autoimmunity to environmental toxins
-
DOI 10.1038/nature06881, PII NATURE06881
-
Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B: The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature, 2008, 453, 106-109 (Pubitemid 351630329).
-
(2008)
Nature
, vol.453
, Issue.7191
, pp. 106-109
-
-
Veldhoen, M.1
Hirota, K.2
Westendorf, A.M.3
Buer, J.4
Dumoutier, L.5
Renauld, J.-C.6
Stockinger, B.7
-
101
-
-
32244442562
-
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
DOI 10.1016/j.immuni.2006.01.001, PII S1074761306000045
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B: TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL- 17-producing T cells. Immunity, 2006, 24, 179-189 (Pubitemid 43214587).
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
102
-
-
44049102724
-
H-17 responses
-
H-17 responses. Nat Immunol, 2008, 9, 650-657.
-
(2008)
Nat Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
Servant, N.2
Zollinger, R.3
Bogiatzi, S.I.4
Hupe, P.5
Barillot, E.6
Soumelis, V.7
-
103
-
-
33846864685
-
Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor
-
DOI 10.1182/blood-2006-04-019398
-
Wada Y, Lu R, Zhou D, Chu J, Przewloka T, Zhang S, Li L et al.: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109, 1156-1164 (Pubitemid 46220663).
-
(2007)
Blood
, vol.109
, Issue.3
, pp. 1156-1164
-
-
Wada, Y.1
Lu, R.2
Zhou, D.3
Chu, J.4
Przewloka, T.5
Zhang, S.6
Li, L.7
Wu, Y.8
Qin, J.9
Balasubramanyam, V.10
Barsoum, J.11
Ono, M.12
-
104
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
DOI 10.1038/ni1497, PII NI1497
-
Wilson NJ, Boniface K, Chan JR, McKenzie BS, Blumenschein WM, Mattson JD, Basham B et al.: Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol, 2007, 8, 950-957 (Pubitemid 47300009).
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
Basham, B.7
Smith, K.8
Chen, T.9
Morel, F.10
Lecron, J.-C.11
Kastelein, R.A.12
Cua, D.J.13
McClanahan, T.K.14
Bowman, E.P.15
De Malefyt, R.W.16
-
105
-
-
47549112840
-
H17 cells
-
H17 cells. Nature, 2008, 454, 350-352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
Hastings, W.D.4
Bettelli, E.5
Oukka, M.6
Kuchroo, V.K.7
Hafler, D.A.8
-
106
-
-
43549110961
-
Regulation of inflammatory responses by IL-17F
-
DOI 10.1084/jem.20071978
-
Yang XO, Chang SH, Park H, Nurieva R, Shah B, Acero L, Wang YH et al.: Regulation of inflammatory responses by IL-17F. J Exp Med, 2008, 205, 1063-1075 (Pubitemid 351679682).
-
(2008)
Journal of Experimental Medicine
, vol.205
, Issue.5
, pp. 1063-1075
-
-
Yang, X.O.1
Seon, H.C.2
Park, H.3
Nurieva, R.4
Shah, B.5
Acero, L.6
Wang, Y.-H.7
Schluns, K.S.8
Broaddus, R.R.9
Zhu, Z.10
Dong, C.11
-
107
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP, Shah B et al.: Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity, 2008, 29, 44-56.
-
(2008)
Immunity
, vol.29
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
Kang, H.S.4
Chung, Y.5
Pappu, B.P.6
Shah, B.7
-
108
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ
-
Yang XO, Pappu BP, Nurieva R, Akimzhanov A, Kang HS, Chung Y, Ma L et al.: T helper 17 lineage differentiation is programmed by orphan nuclear receptors RORα and RORγ. Immunity, 2008, 28, 29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
-
109
-
-
0029555301
-
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
-
DOI 10.1016/1074-7613(95)90070-5
-
Yao Z, Fanslow WC, Seldin MF, Rousseau AM, Painter SL, Comeau MR, Cohen JI, Spriggs MK: Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity, 1995, 3, 811-821 (Pubitemid 26091152).
-
(1995)
Immunity
, vol.3
, Issue.6
, pp. 811-821
-
-
Yao, Z.1
Fanslow, W.C.2
Seldin, M.F.3
Rousseau, A.-M.4
Painter, S.L.5
Comeau, M.R.6
Cohen, J.I.7
Spriggs, M.K.8
-
110
-
-
71749085498
-
Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
-
Zaba LC, Suarez-Farinas M, Fuentes-Duculan J, Nograles KE, Guttman-Yassky E, Cardinale I, Lowes MA, Krueger JG: Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes. J Allergy Clin Immunol, 2009, 124, 1022-1030 e. 395.
-
(2009)
J Allergy Clin Immunol
, vol.124
-
-
Zaba, L.C.1
Suarez-Farinas, M.2
Fuentes-Duculan, J.3
Nograles, K.E.4
Guttman-Yassky, E.5
Cardinale, I.6
Lowes, M.A.7
Krueger, J.G.8
-
111
-
-
45549102525
-
Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes
-
Zhang X, Jin J, Peng X, Ramgolam VS, Markovic-Plese S: Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes. J Immunol, 2008, 180, 6988-6996.
-
(2008)
J Immunol
, vol.180
, pp. 6988-6996
-
-
Zhang, X.1
Jin, J.2
Peng, X.3
Ramgolam, V.S.4
Markovic-Plese, S.5
-
112
-
-
33646804892
-
Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
-
Zhang Z, Zheng M, Bindas J, Schwarzenberger P, Kolls JK: Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis, 2006, 12, 382-388.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 382-388
-
-
Zhang, Z.1
Zheng, M.2
Bindas, J.3
Schwarzenberger, P.4
Kolls, J.K.5
-
113
-
-
33846906224
-
H17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
DOI 10.1038/nature05505, PII NATURE05505
-
Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham- Anderson J, Wu J, Ouyang W: Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature, 2007, 445, 648-651 (Pubitemid 46232884).
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
Kasman, I.4
Eastham-Anderson, J.5
Wu, J.6
Ouyang, W.7
-
114
-
-
34547188748
-
H-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
DOI 10.1038/ni1488, PII NI1488
-
Zhou L, Ivanov, II, Spolski R, Min R, Shenderov K, Egawa T, Levy DE et al.: IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol, 2007, 8, 967-974 (Pubitemid 47300011).
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
Levy, D.E.7
Leonard, W.J.8
Littman, D.R.9
-
115
-
-
43449135305
-
H17 cell differentiation by antagonizing RORγt function
-
H17 cell differentiation by antagonizing RORγt function. Nature, 2008, 453, 236-240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
Ivanov, I.I.4
Min, R.5
Victora, G.D.6
Shen, Y.7
|