메뉴 건너뛰기




Volumn 7, Issue 10, 2012, Pages

Roles of Spatial Parameters on the Oscillation of Nuclear NF-κB: Computer Simulations of a 3D Spherical Cell

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 84867091567     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046911     Document Type: Article
Times cited : (15)

References (67)
  • 1
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim HJ, Hawke N, Baldwin AS, (2006) NF-kappaB and IKK as therapeutic targets in cancer. Cell Death Differ 13: 738-747.
    • (2006) Cell Death Differ , vol.13 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 2
    • 0037417136 scopus 로고    scopus 로고
    • Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference
    • Zhou A, Scoggin S, Gaynor RB, Williams NS, (2003) Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference. Oncogene 22: 2054-2064.
    • (2003) Oncogene , vol.22 , pp. 2054-2064
    • Zhou, A.1    Scoggin, S.2    Gaynor, R.B.3    Williams, N.S.4
  • 3
    • 72549111131 scopus 로고    scopus 로고
    • The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy
    • Lin Y, Bai L, Chen W, Xu S, (2010) The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy. Expert Opin Ther Targets 14: 45-55.
    • (2010) Expert Opin Ther Targets , vol.14 , pp. 45-55
    • Lin, Y.1    Bai, L.2    Chen, W.3    Xu, S.4
  • 4
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW, (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2: 301-310.
    • (2002) Nat Rev Cancer , vol.2 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 5
    • 70350469057 scopus 로고    scopus 로고
    • Dynamic advances in NF-kappaB signaling analysis
    • Kobayashi T, Kageyama R, (2009) Dynamic advances in NF-kappaB signaling analysis. Sci Signal 2: pe47.
    • (2009) Sci Signal , vol.2
    • Kobayashi, T.1    Kageyama, R.2
  • 6
    • 43249106836 scopus 로고    scopus 로고
    • Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling
    • Moss BL, Gross S, Gammon ST, Vinjamoori A, Piwnica-Worms D, (2008) Identification of a ligand-induced transient refractory period in nuclear factor-kappaB signaling. J Biol Chem 283: 8687-8698.
    • (2008) J Biol Chem , vol.283 , pp. 8687-8698
    • Moss, B.L.1    Gross, S.2    Gammon, S.T.3    Vinjamoori, A.4    Piwnica-Worms, D.5
  • 7
    • 33846685017 scopus 로고    scopus 로고
    • NF-kappaB activation in development and progression of cancer
    • Inoue J, Gohda J, Akiyama T, Semba K, (2007) NF-kappaB activation in development and progression of cancer. Cancer Sci 98: 268-274.
    • (2007) Cancer Sci , vol.98 , pp. 268-274
    • Inoue, J.1    Gohda, J.2    Akiyama, T.3    Semba, K.4
  • 8
    • 77951622671 scopus 로고    scopus 로고
    • A20: from ubiquitin editing to tumour suppression
    • Hymowitz SG, Wertz IE, (2010) A20: from ubiquitin editing to tumour suppression. Nat Rev Cancer 10: 332-341.
    • (2010) Nat Rev Cancer , vol.10 , pp. 332-341
    • Hymowitz, S.G.1    Wertz, I.E.2
  • 9
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen ZJ, (2005) Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 7: 758-765.
    • (2005) Nat Cell Biol , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 10
    • 77951089274 scopus 로고    scopus 로고
    • NF-kappaB signaling: a tale of two pathways in skeletal myogenesis
    • Bakkar N, Guttridge DC, (2010) NF-kappaB signaling: a tale of two pathways in skeletal myogenesis. Physiol Rev 90: 495-511.
    • (2010) Physiol Rev , vol.90 , pp. 495-511
    • Bakkar, N.1    Guttridge, D.C.2
  • 11
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
    • Perkins ND, (2006) Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene 25: 6717-6730.
    • (2006) Oncogene , vol.25 , pp. 6717-6730
    • Perkins, N.D.1
  • 12
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-kappaB
    • Hayden MS, Ghosh S, (2004) Signaling to NF-kappaB. Genes Dev 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 13
    • 11844269840 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation
    • Viatour P, Merville MP, Bours V, Chariot A, (2005) Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem Sci 30: 43-52.
    • (2005) Trends Biochem Sci , vol.30 , pp. 43-52
    • Viatour, P.1    Merville, M.P.2    Bours, V.3    Chariot, A.4
  • 14
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden MS, Ghosh S, (2008) Shared principles in NF-kappaB signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 15
    • 68749115366 scopus 로고    scopus 로고
    • Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins
    • Carpenter S, O'Neill LA, (2009) Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins. Biochem J 422: 1-10.
    • (2009) Biochem J , vol.422 , pp. 1-10
    • Carpenter, S.1    O'Neill, L.A.2
  • 16
    • 33750443289 scopus 로고    scopus 로고
    • IkappaB kinase complexes: gateways to NF-kappaB activation and transcription
    • Scheidereit C, (2006) IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene 25: 6685-6705.
    • (2006) Oncogene , vol.25 , pp. 6685-6705
    • Scheidereit, C.1
  • 17
    • 77950367657 scopus 로고    scopus 로고
    • Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling
    • Yamazaki K, Gohda J, Kanayama A, Miyamoto Y, Sakurai H, et al. (2009) Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling. SciSignal 2: ra66.
    • (2009) SciSignal , vol.2
    • Yamazaki, K.1    Gohda, J.2    Kanayama, A.3    Miyamoto, Y.4    Sakurai, H.5
  • 18
    • 79955599141 scopus 로고    scopus 로고
    • Intrinsic and extrinsic regulation of innate immune receptors
    • Jeong E, Lee JY, (2011) Intrinsic and extrinsic regulation of innate immune receptors. Yonsei Med J 52: 379-392.
    • (2011) Yonsei Med J , vol.52 , pp. 379-392
    • Jeong, E.1    Lee, J.Y.2
  • 19
    • 33845321931 scopus 로고    scopus 로고
    • Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity
    • Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, et al. (2006) Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci U S A 103: 18154-18159.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 18154-18159
    • Cummins, E.P.1    Berra, E.2    Comerford, K.M.3    Ginouves, A.4    Fitzgerald, K.T.5
  • 20
    • 0032589462 scopus 로고    scopus 로고
    • IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain
    • Sakurai H, Chiba H, Miyoshi H, Sugita T, Toriumi W, (1999) IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain. J Biol Chem 274: 30353-30356.
    • (1999) J Biol Chem , vol.274 , pp. 30353-30356
    • Sakurai, H.1    Chiba, H.2    Miyoshi, H.3    Sugita, T.4    Toriumi, W.5
  • 21
    • 0032575379 scopus 로고    scopus 로고
    • Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate
    • Zandi E, Chen Y, Karin M, (1998) Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate. Science 281: 1360-1363.
    • (1998) Science , vol.281 , pp. 1360-1363
    • Zandi, E.1    Chen, Y.2    Karin, M.3
  • 22
    • 0036144763 scopus 로고    scopus 로고
    • Regulatory functions of ubiquitination in the immune system
    • Ben-Neriah Y, (2002) Regulatory functions of ubiquitination in the immune system. Nat Immunol 3: 20-26.
    • (2002) Nat Immunol , vol.3 , pp. 20-26
    • Ben-Neriah, Y.1
  • 23
    • 0037044575 scopus 로고    scopus 로고
    • The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
    • Hoffmann A, Levchenko A, Scott ML, Baltimore D, (2002) The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298: 1241-1245.
    • (2002) Science , vol.298 , pp. 1241-1245
    • Hoffmann, A.1    Levchenko, A.2    Scott, M.L.3    Baltimore, D.4
  • 24
    • 64849104716 scopus 로고    scopus 로고
    • Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription
    • Ashall L, Horton CA, Nelson DE, Paszek P, Harper CV, et al. (2009) Pulsatile stimulation determines timing and specificity of NF-kappaB-dependent transcription. Science 324: 242-246.
    • (2009) Science , vol.324 , pp. 242-246
    • Ashall, L.1    Horton, C.A.2    Nelson, D.E.3    Paszek, P.4    Harper, C.V.5
  • 25
    • 70349687069 scopus 로고    scopus 로고
    • Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles
    • Sung MH, Salvatore L, De Lorenzi R, Indrawan A, Pasparakis M, et al. (2009) Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles. PLoS One 4: e7163.
    • (2009) PLoS One , vol.4
    • Sung, M.H.1    Salvatore, L.2    De Lorenzi, R.3    Indrawan, A.4    Pasparakis, M.5
  • 26
    • 28744455886 scopus 로고    scopus 로고
    • The strength of indecisiveness: oscillatory behavior for better cell fate determination
    • Lahav G, (2004) The strength of indecisiveness: oscillatory behavior for better cell fate determination. Sci STKE 2004: pe55.
    • (2004) Sci STKE , vol.2004
    • Lahav, G.1
  • 27
    • 79959343390 scopus 로고    scopus 로고
    • Two-phase dynamics of p53 in the DNA damage response
    • Zhang XP, Liu F, Wang W, (2011) Two-phase dynamics of p53 in the DNA damage response. Proc Natl Acad Sci U S A 108: 8990-8995.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 8990-8995
    • Zhang, X.P.1    Liu, F.2    Wang, W.3
  • 29
    • 33747388013 scopus 로고    scopus 로고
    • IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression
    • Kearns JD, Basak S, Werner SL, Huang CS, Hoffmann A, (2006) IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression. J Cell Biol 173: 659-664.
    • (2006) J Cell Biol , vol.173 , pp. 659-664
    • Kearns, J.D.1    Basak, S.2    Werner, S.L.3    Huang, C.S.4    Hoffmann, A.5
  • 30
    • 66449092314 scopus 로고    scopus 로고
    • Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity
    • Shih VF, Kearns JD, Basak S, Savinova OV, Ghosh G, et al. (2009) Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity. Proc Natl Acad Sci U S A 106: 9619-9624.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9619-9624
    • Shih, V.F.1    Kearns, J.D.2    Basak, S.3    Savinova, O.V.4    Ghosh, G.5
  • 31
    • 68949206434 scopus 로고    scopus 로고
    • Mechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach
    • Witt J, Barisic S, Schumann E, Allgower F, Sawodny O, et al. (2009) Mechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach. BMC Syst Biol 3: 71.
    • (2009) BMC Syst Biol , vol.3 , pp. 71
    • Witt, J.1    Barisic, S.2    Schumann, E.3    Allgower, F.4    Sawodny, O.5
  • 32
    • 31444432847 scopus 로고    scopus 로고
    • The influence of the signal dynamics of activated form of IKK on NF-kappaB and anti-apoptotic gene expressions: a systems biology approach
    • Park SG, Lee T, Kang HY, Park K, Cho KH, et al. (2006) The influence of the signal dynamics of activated form of IKK on NF-kappaB and anti-apoptotic gene expressions: a systems biology approach. FEBS Lett 580: 822-830.
    • (2006) FEBS Lett , vol.580 , pp. 822-830
    • Park, S.G.1    Lee, T.2    Kang, H.Y.3    Park, K.4    Cho, K.H.5
  • 33
    • 43249090157 scopus 로고    scopus 로고
    • UV as an amplifier rather than inducer of NF-kappaB activity
    • O'Dea EL, Kearns JD, Hoffmann A, (2008) UV as an amplifier rather than inducer of NF-kappaB activity. Mol Cell 30: 632-641.
    • (2008) Mol Cell , vol.30 , pp. 632-641
    • O'Dea, E.L.1    Kearns, J.D.2    Hoffmann, A.3
  • 34
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner SL, Barken D, Hoffmann A, (2005) Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309: 1857-1861.
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 36
    • 36248988492 scopus 로고    scopus 로고
    • Sensitivity analysis of a computational model of the IKK NF-kappaB IkappaBalpha A20 signal transduction network
    • Joo J, Plimpton S, Martin S, Swiler L, Faulon JL, (2007) Sensitivity analysis of a computational model of the IKK NF-kappaB IkappaBalpha A20 signal transduction network. Ann N Y Acad Sci 1115: 221-239.
    • (2007) Ann N Y Acad Sci , vol.1115 , pp. 221-239
    • Joo, J.1    Plimpton, S.2    Martin, S.3    Swiler, L.4    Faulon, J.L.5
  • 37
    • 70349328548 scopus 로고    scopus 로고
    • Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits
    • Kim D, Kolch W, Cho KH, (2009) Multiple roles of the NF-kappaB signaling pathway regulated by coupled negative feedback circuits. FASEB J 23: 2796-2802.
    • (2009) FASEB J , vol.23 , pp. 2796-2802
    • Kim, D.1    Kolch, W.2    Cho, K.H.3
  • 38
    • 38849139572 scopus 로고    scopus 로고
    • Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling
    • Lipniacki T, Puszynski K, Paszek P, Brasier AR, Kimmel M, (2007) Single TNFalpha trimers mediating NF-kappaB activation: stochastic robustness of NF-kappaB signaling. BMC Bioinformatics 8: 376.
    • (2007) BMC Bioinformatics , vol.8 , pp. 376
    • Lipniacki, T.1    Puszynski, K.2    Paszek, P.3    Brasier, A.R.4    Kimmel, M.5
  • 39
    • 33646817119 scopus 로고    scopus 로고
    • NF-kappaB oscillations and cell-to-cell variability
    • Hayot F, Jayaprakash C, (2006) NF-kappaB oscillations and cell-to-cell variability. J Theor Biol 240: 583-591.
    • (2006) J Theor Biol , vol.240 , pp. 583-591
    • Hayot, F.1    Jayaprakash, C.2
  • 41
    • 77954541844 scopus 로고    scopus 로고
    • Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing
    • Tay S, Hughey JJ, Lee TK, Lipniacki T, Quake SR, et al. (2010) Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing. Nature 466: 267-271.
    • (2010) Nature , vol.466 , pp. 267-271
    • Tay, S.1    Hughey, J.J.2    Lee, T.K.3    Lipniacki, T.4    Quake, S.R.5
  • 42
    • 33746605149 scopus 로고    scopus 로고
    • Minimal model of spiky oscillations in NF-kappaB signaling
    • Krishna S, Jensen MH, Sneppen K, (2006) Minimal model of spiky oscillations in NF-kappaB signaling. Proc Natl Acad Sci U S A 103: 10840-10845.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 10840-10845
    • Krishna, S.1    Jensen, M.H.2    Sneppen, K.3
  • 43
    • 0013823048 scopus 로고
    • Oscillatory Behavior in Enzymatic Control Processes
    • Goodwin BC, (1965) Oscillatory Behavior in Enzymatic Control Processes. AdvEnzymolReg 3: 425-438.
    • (1965) AdvEnzymolReg , vol.3 , pp. 425-438
    • Goodwin, B.C.1
  • 44
    • 0021171678 scopus 로고
    • Models of genetic control by repression with time delays and spatial effects
    • Mahaffy JM, Pao CV, (1984) Models of genetic control by repression with time delays and spatial effects. J Math Biol 20: 39-57.
    • (1984) J Math Biol , vol.20 , pp. 39-57
    • Mahaffy, J.M.1    Pao, C.V.2
  • 45
    • 80052826648 scopus 로고    scopus 로고
    • Spatio-temporal modelling of the NF-kappaB intracellular signalling pathway: the roles of diffusion, active transport, and cell geometry
    • Terry AJ, Chaplain MA, (2011) Spatio-temporal modelling of the NF-kappaB intracellular signalling pathway: the roles of diffusion, active transport, and cell geometry. J Theor Biol 290: 7-26.
    • (2011) J Theor Biol , vol.290 , pp. 7-26
    • Terry, A.J.1    Chaplain, M.A.2
  • 46
    • 0031000601 scopus 로고    scopus 로고
    • Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion
    • Swaminathan R, Hoang CP, Verkman AS, (1997) Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion. Biophys J 72: 1900-1907.
    • (1997) Biophys J , vol.72 , pp. 1900-1907
    • Swaminathan, R.1    Hoang, C.P.2    Verkman, A.S.3
  • 47
    • 0000037251 scopus 로고    scopus 로고
    • Rapid diffusion of green fluorescent protein in the mitochondrial matrix
    • Partikian A, Olveczky B, Swaminathan R, Li Y, Verkman AS, (1998) Rapid diffusion of green fluorescent protein in the mitochondrial matrix. J Cell Biol 140: 821-829.
    • (1998) J Cell Biol , vol.140 , pp. 821-829
    • Partikian, A.1    Olveczky, B.2    Swaminathan, R.3    Li, Y.4    Verkman, A.S.5
  • 48
    • 0033059157 scopus 로고    scopus 로고
    • Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum
    • Dayel MJ, Hom EF, Verkman AS, (1999) Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophys J 76: 2843-2851.
    • (1999) Biophys J , vol.76 , pp. 2843-2851
    • Dayel, M.J.1    Hom, E.F.2    Verkman, A.S.3
  • 49
    • 80053160633 scopus 로고    scopus 로고
    • Proteins on the move: insights gained from fluorescent protein technologies
    • Miyawaki A, (2011) Proteins on the move: insights gained from fluorescent protein technologies. Nat Rev Mol Cell Biol 12: 656-668.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 656-668
    • Miyawaki, A.1
  • 51
    • 0347156907 scopus 로고    scopus 로고
    • Single mRNA molecules demonstrate probabilistic movement in living mammalian cells
    • Fusco D, Accornero N, Lavoie B, Shenoy SM, Blanchard JM, et al. (2003) Single mRNA molecules demonstrate probabilistic movement in living mammalian cells. Curr Biol 13: 161-167.
    • (2003) Curr Biol , vol.13 , pp. 161-167
    • Fusco, D.1    Accornero, N.2    Lavoie, B.3    Shenoy, S.M.4    Blanchard, J.M.5
  • 53
    • 36348936770 scopus 로고    scopus 로고
    • The size-wise nucleus: nuclear volume control in eukaryotes
    • Huber MD, Gerace L, (2007) The size-wise nucleus: nuclear volume control in eukaryotes. J Cell Biol 179: 583-584.
    • (2007) J Cell Biol , vol.179 , pp. 583-584
    • Huber, M.D.1    Gerace, L.2
  • 54
    • 36348943531 scopus 로고    scopus 로고
    • Nuclear size control in fission yeast
    • Neumann FR, Nurse P, (2007) Nuclear size control in fission yeast. J Cell Biol 179: 593-600.
    • (2007) J Cell Biol , vol.179 , pp. 593-600
    • Neumann, F.R.1    Nurse, P.2
  • 55
    • 0033814836 scopus 로고    scopus 로고
    • Clinical applications of image cytometry to human tumour analysis
    • Millot C, Dufer J, (2000) Clinical applications of image cytometry to human tumour analysis. Histol Histopathol 15: 1185-1200.
    • (2000) Histol Histopathol , vol.15 , pp. 1185-1200
    • Millot, C.1    Dufer, J.2
  • 56
    • 0026045818 scopus 로고
    • Correlation of nuclear morphometry with progression of breast cancer
    • Pienta KJ, Coffey DS, (1991) Correlation of nuclear morphometry with progression of breast cancer. Cancer 68: 2012-2016.
    • (1991) Cancer , vol.68 , pp. 2012-2016
    • Pienta, K.J.1    Coffey, D.S.2
  • 57
    • 0028799875 scopus 로고
    • The prognostic value of morphometry in advanced epithelial ovarian cancers
    • Katsoulis M, Lekka J, Vlachonikolis I, Delides GS, (1995) The prognostic value of morphometry in advanced epithelial ovarian cancers. Br J Cancer 72: 958-963.
    • (1995) Br J Cancer , vol.72 , pp. 958-963
    • Katsoulis, M.1    Lekka, J.2    Vlachonikolis, I.3    Delides, G.S.4
  • 58
    • 0026552212 scopus 로고
    • Comparison of morphonuclear features in normal, benign and neoplastic thyroid tissue by digital cell image analysis
    • Salmon I, Kiss R, Franc B, Gasperin P, Heimann R, et al. (1992) Comparison of morphonuclear features in normal, benign and neoplastic thyroid tissue by digital cell image analysis. Anal Quant Cytol Histol 14: 47-54.
    • (1992) Anal Quant Cytol Histol , vol.14 , pp. 47-54
    • Salmon, I.1    Kiss, R.2    Franc, B.3    Gasperin, P.4    Heimann, R.5
  • 60
    • 67649435612 scopus 로고    scopus 로고
    • Nuclear pore proteins and cancer
    • Xu S, Powers MA, (2009) Nuclear pore proteins and cancer. Semin Cell Dev Biol 20: 620-630.
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 620-630
    • Xu, S.1    Powers, M.A.2
  • 61
    • 0345580750 scopus 로고    scopus 로고
    • The nuclear pore complex protein Nup88 is overexpressed in tumor cells
    • Martinez N, Alonso A, Moragues MD, Ponton J, Schneider J, (1999) The nuclear pore complex protein Nup88 is overexpressed in tumor cells. Cancer Res 59: 5408-5411.
    • (1999) Cancer Res , vol.59 , pp. 5408-5411
    • Martinez, N.1    Alonso, A.2    Moragues, M.D.3    Ponton, J.4    Schneider, J.5
  • 62
    • 84856002587 scopus 로고    scopus 로고
    • Dynamical modeling of three-dimensional genome organization in interphase budding yeast
    • Tokuda N, Terada TP, Sasai M, (2012) Dynamical modeling of three-dimensional genome organization in interphase budding yeast. Biophys J 102: 296-304.
    • (2012) Biophys J , vol.102 , pp. 296-304
    • Tokuda, N.1    Terada, T.P.2    Sasai, M.3
  • 63
    • 1342265607 scopus 로고    scopus 로고
    • Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κB Signal Transduction Pathway
    • Cho K, Shin S, Kolch W, Wolkenhauer O, (2003) Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κB Signal Transduction Pathway. Simulation 79: 726-739.
    • (2003) Simulation , vol.79 , pp. 726-739
    • Cho, K.1    Shin, S.2    Kolch, W.3    Wolkenhauer, O.4
  • 64
    • 15944426727 scopus 로고    scopus 로고
    • Comment on "Oscillations in NF-kappaB signaling control the dynamics of gene expression"
    • author reply 52
    • Barken D, Wang CJ, Kearns J, Cheong R, Hoffmann A, et al. (2005) Comment on "Oscillations in NF-kappaB signaling control the dynamics of gene expression". Science 308: 52; author reply 52.
    • (2005) Science , vol.308 , pp. 52
    • Barken, D.1    Wang, C.J.2    Kearns, J.3    Cheong, R.4    Hoffmann, A.5
  • 65
    • 7444254365 scopus 로고    scopus 로고
    • Oscillations in NF-kappaB signaling control the dynamics of gene expression
    • Nelson DE, Ihekwaba AE, Elliott M, Johnson JR, Gibney CA, et al. (2004) Oscillations in NF-kappaB signaling control the dynamics of gene expression. Science 306: 704-708.
    • (2004) Science , vol.306 , pp. 704-708
    • Nelson, D.E.1    Ihekwaba, A.E.2    Elliott, M.3    Johnson, J.R.4    Gibney, C.A.5
  • 66
    • 0035022861 scopus 로고    scopus 로고
    • A-Cell: graphical user interface for the construction of biochemical reaction models
    • Ichikawa K, (2001) A-Cell: graphical user interface for the construction of biochemical reaction models. Bioinformatics 17: 483-484.
    • (2001) Bioinformatics , vol.17 , pp. 483-484
    • Ichikawa, K.1
  • 67
    • 24944520116 scopus 로고    scopus 로고
    • A modeling environment with three-dimensional morphology, A-Cell-3D, and Ca2+ dynamics in a spine
    • Ichikawa K, (2005) A modeling environment with three-dimensional morphology, A-Cell-3D, and Ca2+ dynamics in a spine. Neuroinformatics 3: 49-64.
    • (2005) Neuroinformatics , vol.3 , pp. 49-64
    • Ichikawa, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.