Dynamic advances in NF-κB signaling analysis

Science Signaling

Volumn 2, Issue 81, 2009, Pages

  Kobayashi, Taeko ^a,b   Kageyama, Ryoichiro ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; I KAPPA B; I KAPPA B KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

CELL STIMULATION; GENE CONTROL; GENE EXPRESSION; GENE FREQUENCY; IMMUNE RESPONSE; OSCILLATION; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL NUCLEUS; ENZYME ACTIVATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL NUCLEUS; ENZYME ACTIVATION; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MODELS, BIOLOGICAL; NF-KAPPA B; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 70350469057     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.281pe47     Document Type: Short Survey

References (11)

1. A. Hoffmann, D. Baltimore, Circuitry of nuclear factor κB signaling. Immunol. Rev. 210, 171-186 (2006).
2. B. Tian, D. E. Nowak, A. R. Brasier, A TNF-induced gene expression program under oscillatory NF-κB control.BMC Genomics 6, 137 (2005).
3. M. S. Hayden, S. Ghosh, Shared principles in NF-κB signaling. Cell 132, 344-362 (2008).
4. A. Hoffmann, A. Levchenko, M. L. Scott, D. Baltimore, The κB-NF-κB signaling module: Temporal control and selective gene activation. Science 298, 1241-1245 (2002).
5. D. E. Nelson, A. E. C. Ihekwaba, M. Elliott, J. R. Johnson, C. A. Gibney, B. E. Foreman, G. Nelson, V. See, C. A. Horton, D. G. Spiller, S. W. Edwards, H. P. McDowell, J. F. Unitt, E. Sullivan, R. Grimley, N. Benson, D. Broomhead, D. B. Kell, M. R. H. White, Oscillations in NF-κB signaling control the dynamics of gene expression. Science 306, 704-708 (2004). (Pubitemid 39440922)
6. L. Ashall, C. A. Horton, D. E. Nelson, P. Paszek, C. V. Harper, K. Sillitoe, S. Ryan, D. G. Spiller, J. F. Unitt, D. S. Broomhead, D. B. Kell, D. A. Rand, V. Sée, M. R. H. White, Pulsatile stimulation determines timing and specificity of NF-κB-dependent transcription. Science 324, 242-246 (2009).
7. M. W. Covert, T. H. Leung, J. E. Gaston, D. Baltimore, Achieving stability of lipopolysaccharideinduced NF-κB activation. Science 309, 1854-1857 (2005).
8. S. L. Werner, D. Barken, A. Hoffmannn, Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309, 1857-1861 (2005).
9. N. D. Perkins, Integrating cell-signaling pathways with NF-κB and IKK function. Nat. Rev. Mol. Cell Biol. 8, 49-62 (2007).
10. H. Shimojo, T. Ohtsuka, R. Kageyama, Oscillations in Notch signaling regulate maintenance of neural progenitors. Neuron 58, 52-64 (2008).
11. R. Kageyama, T. Ohtsuka, H. Shimojo, I. Imayoshi, Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition. Nat. Neurosci. 11, 1247-1251 (2008).