Experimental Design in Systems Biology, Based on Parameter Sensitivity Analysis Using a Monte Carlo Method: A Case Study for the TNFα-Mediated NF-κB Signal Transduction Pathway

Simulation

Volumn 79, Issue 12, 2003, Pages 726-739

  Cho, Kwang Hyun ^a   Shin, Sung Young ^a   Kolch, Walter ^b,c   Wolkenhauer, Olaf ^d  

^a University of Ulsan   (South Korea)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Experimental design; Mathematical modeling; Monte Carlo method; NF B; Parametric sensitivity; Signal transduction pathway; Systems biology; TNF

Indexed keywords

BIOCHEMISTRY; CELLS; COMPUTER SIMULATION; CORRELATION METHODS; MATHEMATICAL MODELS; MONTE CARLO METHODS; PRODUCT DESIGN; PROTEINS;

EXPERIMENTAL DESIGN (ED); NF-ΚB; PARAMETER SENSITIVITY; SIGNAL TRANSDUCTION PATHWAY; SYSTEMS BIOLOGY; TNFΑ;

SIGNAL PROCESSING;

EID: 1342265607     PISSN: 00375497     EISSN: None     Source Type: Journal    
DOI: 10.1177/0037549703040943     Document Type: Article

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