Microfluidics for monitoring oxidative stress and antioxidant capacity

Current Analytical Chemistry

Volumn 8, Issue 4, 2012, Pages 456-471

  Ortiz, Pedro ^a   Muñoz Berbel, Xavier ^a   Gonzalo Ruiz, Javier ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Antioxidant Capacity Determination; Capillary Electrophoresis; Drug Screening; Lab On A Chip; Oxidative Stress

Indexed keywords

ANTIOXIDANTS; DIAGNOSIS; DISEASES; MICROFLUIDICS; MOLECULAR BIOLOGY; OXIDATIVE STRESS; OXYGEN;

ANTIOXIDANT CAPACITY; ANTIOXIDANT CAPACITY DETERMINATION; CANCER DISEASE; DRUG-SCREENING; GENOMICS; LAB-ON-A-CHIP; LIFE-SCIENCES; MICROFLUIDICS TECHNOLOGY; PROTEOMICS; REACTIVE OXYGEN SPECIES;

CAPILLARY ELECTROPHORESIS;

EID: 84867005659     PISSN: 15734110     EISSN: None     Source Type: Journal    
DOI: 10.2174/157341112803216708     Document Type: Review

References (95)

1. Manz, A.; Graber, N.; Widmer, H.M. Miniaturized total chemical analysis systems: A novel concept for chemical sensing. Sensors and Actuators: B. Chemical, 1990, 1(1-6), 244-248.
2. Manz, A.; Harrison, D.J.; Verpoorte, E.M.J.; Fettinger, J.C.; Paulus, A.; Ludi, H.; Widmer, H.M. Planar chips technology for miniaturization and integration of separation techniques into monitoring systems. Capillary electrophoresis on a chip. Journal of Chromatography, 1992, 593(1-2), 253-258.
3. Stone, H.A.; Stroock, A.D.; Ajdari, A. Engineering flows in small devices: Microfluidics toward a lab-on-a-chip. Annual Review of Fluid Mechanics 2004, 36, 381-411.
4. Whitesides, G.M. The origins and the future of microfluidics. Nature, 2006, 442(7101), 368-373.
5. Kovacs, G.T.A.; Maluf, N.I.; Petersen, K.E. Bulk micromachining of silicon. Proceedings of the IEEE, 1998, 86(8), 1536-1551.
6. Bustjllo, J.M.; Howe, R.T.; Muller, R.S. Surface micromachining for microelectromechanical systems. Proceedings of the IEEE, 1998, 86(8), 1552-1573.
7. Xia, Y.; Whitesides, G.M. Soft lithography. Annual Review of Materials Science, 1998, 28(1), 153-184.
8. Madou, M.J., Fundamentals of Microfabrication: The Science of Miniaturization. 2nd ed. ed. 2002, Boca Raton, FL, USA: CRC Press.
9. Ames, B.N.; Shigenaga, M.K.; Hagen, T.M. Oxidants, antioxidants, and the degenerative diseases of aging. Proceedings of the National Academy of Sciences, 1993, 90(17), 7915-7922.
10. Sohal, R.S.; Weindruch, R. Oxidative Stress, Caloric Restriction, and Aging. Science, 1996, 273(5271), 59-63.
11. [] Lopaczynski, W.; Zeisel, S.H. Antioxidants, programmed cell death, and cancer. Nutrition Research, 21(1-2), 295-307.
12. Buonocore, G.; Perrone, S.; Tataranno, M.L. Oxygen toxicity: chemistry and biology of reactive oxygen species. Seminars in Fetal and Neonatal Medicine, 2010, 15(4), 186-190.
13. Davies, K.J.A.; Ursini, F., eds. The oxygen paradox. 1995, CLEUP University Press: Padova, Italy.
14. Halliwell, B.; Gutteridge, J.M.C., Free Radicals in Biology and Medicine. 4th Edition ed. 2007, New York: Oxford University Press.
15. Huang, D.; Ou, B.; Prior, R.L. The Chemistry behind Antioxidant Capacity Assays. Journal of Agricultural and Food Chemistry, 2005, 53(6), 1841-1856.
16. Blasco, A.J.; González Crevillén, A.; González, M.C.; Escarpa, A. Direct Electrochemical Sensing and Detection of Natural Antioxidants and Antioxidant Capacity in Vitro Systems. Electroanalysis, 2007, 19(22), 2275-2286.
17. Block, G.; Patterson, B.; Subar, A. Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence. Nutrition and Cancer, 1992, 18(1), 1-29.
18. Byers, T.; Perry, G. Dietary carotenes, vitamin C, and vitamin E as protective antioxidants in human cancers. Annual Review of Nutrition, 1992, 12, 139-159.
19. Daoud, A.H.; Griffin, A.C. Effect of retinoic acid, butylated hydroxytoluene, selenium and sorbic acid on azo-dye hepatocarcinogenesis. Cancer Letters, 1980, 9(4), 299-304.
20. Gaziano, J.M.; Manson, J.E.; Buring, J.E.; Hennekens, C.H.; Sies, H.; Bendich, A. Dietary antioxidants and cardiovascular disease. Annals of the New York Academy of Sciences, 1992, 669, 249-259.
21. Jialal, I.; Grundy, S.M. Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein. Journal of Lipid Research, 1992, 33(6), 899-906.
22. Leske, M.C.; Chylack Jr, L.T.; Wu, S.Y. The Lens Opacities Case-Control Study. Risk factors for cataract. Archives of Ophthalmology, 1991, 109(2), 244-251.
23. Jacques, P.F.; Chylack Jr, L.T. Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. American Journal of Clinical Nutrition, 1991, 53(1 SUPPL.), 352S-355S.
24. Bendich, A.; Butterworth, C.E., Micronutrients in Health and in Disease Prevention. 1991, New York: Marcel Dekker.
25. Jesberger, J.A.; Richardson, J.S. Oxygen free radicals and brain dysfunction. International Journal of Neuroscience, 1991, 57(1-2), 1-17.
26. Finkel, T.; Holbrook, N.J. Oxidants, oxidative stress and the biology of ageing. Nature, 2000, 408(6809), 239-247.
27. Seifried, H.E.; Anderson, D.E.; Fisher, E.I.; Milner, J.A. A review of the interaction among dietary antioxidants and reactive oxygen species. Journal of Nutritional Biochemistry, 2007, 18(9), 567-579.
28. Sánchez-Moreno, C. Review: Methods used to evaluate the free radical scavenging activity in foods and biological systems. Food Science and Technology International, 2002, 8(3), 121-137.
29. Prior, R.L.; Wu, X.; Schaich, K. Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements. Journal of Agricultural and Food Chemistry, 2005, 53(10), 4290-4302.
30. Miller, N.J.; Rice-Evans, C.; Davies, M.J.; Gopinathan, V.; Milner, A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clinical Science, 1993, 84(4), 407-412.
31. Folin, O.; Ciocalteu, V. ON TYROSINE AND TRYPTOPHANE DETERMINATIONS IN PROTEINS. Journal of Biological Chemistry, 1927, 73(2), 627-650.
32. Ghiselli, A.; Serafini, M.; Maiani, G.; Azzini, E.; Ferro-Luzzi, A. A fluorescence-based method for measuring total plasma antioxidant capability. Free Radical Biology and Medicine, 1995, 18(1), 29-36.
33. Whitehead, T.P.; Thorpe, G.H.G.; Maxwell, S.R.J. Enhanced chemiluminescent assay for antioxidant capacity in biological fluids. Analytica Chimica Acta, 1992, 266(2), 265-277.
34. Gamella, M.; Campuzano, S.; Reviejo, A.J.; Pingarrón, J.M. Electrochemical estimation of the polyphenol index in wines using a laccase biosensor. Journal of Agricultural and Food Chemistry, 2006, 54(21), 7960-7967.
35. Escarpa, A.; González, M.C. Approach to the content of total extractable phenolic compounds from different food samples by comparison of chromatographic and spectrophotometric methods. Analytica Chimica Acta, 2001, 427(1), 119-127.
36. Atalay, Y.T.; Vermeir, S.; Witters, D.; Vergauwe, N.; Verbruggen, B.; Verboven, P.; Nicolaï, B.M.; Lammertyn, J. Microfluidic analytical systems for food analysis. Trends in Food Science and Technology, 2011, 22(7), 386-404.
37. Crevillén, A.G.; Hervás, M.; López, M.A.; González, M.C.; Escarpa, A. Real sample analysis on microfluidic devices. Talanta, 2007, 74(3), 342-357.
38. Kuswandi, B.; Nuriman A; Huskens, J.; Verboom, W. Optical sensing systems for microfluidic devices: A review. Analytica Chimica Acta, 2007, 601(2), 141-155.
39. Amatatongchai, M.; Hofmann, O.; Nacapricha, D.; Chailapakul, O.; DeMello, A.J. A microfluidic system for evaluation of antioxidant capacity based on a peroxyoxalate chemiluminescence assay. Analytical and Bioanalytical Chemistry, 2007, 387(1), 277-285.
40. Duffy, D.C.; McDonald, J.C.; Schueller, O.J.A.; Whitesides, G.M. Rapid prototyping of microfluidic systems in poly(dimethylsiloxane). Analytical Chemistry, 1998, 70(23), 4974-4984.
41. Wang, X.; Amatatongchai, M.; Nacapricha, D.; Hofmann, O.; de Mello, J.C.; Bradley, D.D.C.; de Mello, A.J. Thin-film organic photodiodes for integrated on-chip chemiluminescence detection-application to antioxidant capacity screening. Sensors and Actuators, B: Chemical, 2009, 140(2), 643-648.
42. Wang, X.; Hofmann, O.; Das, R.; Barrett, E.M.; DeMello, A.J.; DeMello, J.C.; Bradley, D.D.C. Integrated thin-film polymer/fullerene photodetectors for on-chip microfluidic chemiluminescence detection. Lab on a Chip-Miniaturisation for Chemistry and Biology, 2007, 7(1), 58-63.
43. Milardovic, S.; Kerekovi, I.; Derrico, R.; Rumenjak, V. A novel method for flow injection analysis of total antioxidant capacity using enzymatically produced ABTS{radical dot}+ and biamperometric detector containing interdigitated electrode. Talanta, 2007, 71(1), 213-220.
44. Milardovic, S.; Kerekovi, I.; Rumenjak, V. A flow injection biamperometric method for determination of total antioxidant capacity of alcoholic beverages using bienzymatically produced ABTS{radical dot}+. Food Chemistry, 2007, 105(4), 1688-1694.
45. Krylov, A.V.; Adamzig, H.; Walter, A.D.; Löchel, B.; Kurth, E.; Pulz, O.; Szeponik, J.; Wegerich, F.; Lisdat, F. Parallel generation and detection of superoxide and hydrogen peroxide in a fluidic chip. Sensors and Actuators B: Chemical, 2006, 119(1), 118-126.
46. Krylov, A.V.; Sczech, R.; Lisdat, F. Characterization of antioxidants using a fluidic chip in aqueous/organic media. Analyst, 2007, 132(2), 135-141.
47. Carlsson, J.; Drevin, H.; Axen, R. Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent. Biochemical Journal, 1978, 173(3), 723-737.
48. Krylov, A.V.; Beissenhirtz, M.; Adamzig, H.; Scheller, F.W.; Lisdat, F. Thick-film electrodes for measurement of superoxide and hydrogen peroxide based on direct protein-electrode contacts. Analytical and Bioanalytical Chemistry, 2004, 378(5), 1327-1330.
49. Bravo, L. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance. Nutrition Reviews, 1998, 56(11), 317-333.
50. Cook, N.C.; Samman, S. Flavonoids-Chemistry, metabolism, cardioprotective effects, and dietary sources. Journal of Nutritional Biochemistry, 1996, 7(2), 66-76.
51. Adamson, G.E.; Lazarus, S.A.; Mitchell, A.E.; Prior, R.L.; Cao, G.; Jacobs, P.H.; Kremers, B.G.; Hammerstone, J.F.; Rucker, R.B.; Ritter, K.A.; Schmitz, H.H. HPLC method for the quantification of procyanidins in cocoa and chocolate samples and correlation to total antioxidant capacity. Journal of Agricultural and Food Chemistry, 1999, 47(10), 4184-4188.
52. Kovachev, N.; Canals, A.; Escarpa, A. Fast and selective microfluidic chips for electrochemical antioxidant sensing in complex samples. Analytical Chemistry, 2010, 82(7), 2925-2931.
53. Wang, J.; Tian, B.; Sahlin, E. Micromachined electrophoresis chips with thick-film electrochemical detectors. Analytical Chemistry, 1999, 71(23), 5436-5440.
54. Wang, J.; Escarpa, A.; Pumera, M.; Feldman, J. Capillary electrophoresis-electrochemistry microfluidic system for the determination of organic peroxides. Journal of Chromatography A, 2002, 952(1-2), 249-254.
55. Blasco, A.J.; Barrigas, I.; González, M.C.; Escarpa, A. Fast and simultaneous detection of prominent natural antioxidants using analytical microsystems for capillary electrophoresis with a glassy carbon electrode: A new gateway to food environments. Electrophoresis, 2005, 26(24), 4664-4673.
56. Crevillén, A.G.; Blasco, A.J.; González, M.C.; Escarpa, A. A fast and reliable route integrating calibration and analysis protocols for water-soluble vitamin determination on microchip-electrochemistry platforms. Electrophoresis, 2006, 27(24), 5110-5118.
57. Crevillén, A.G.; Ávila, M.; Pumera, M.; González, M.C.; Escarpa, A. Food analysis on microfluidic devices using ultrasensitive carbon nanotubes detectors. Analytical Chemistry, 2007, 79(19), 7408-7415.
58. Crevillén, A.G.; Pumera, M.; González, M.C.; Escarpa, A. Towards lab-on-a-chip approaches in real analytical domains based on microfluidic chips/electrochemical multi-walled carbon nanotube platforms. Lab on a Chip-Miniaturisation for Chemistry and Biology, 2009, 9(2), 346-353.
59. Shiddiky, M.J.A.; Park, H.; Shim, Y.-B. Direct Analysis of Trace Phenolics with a Microchip: In-Channel Sample Preconcentration, Separation, and Electrochemical Detection. Analytical Chemistry, 2006, 78(19), 6809-6817.
60. Fan, Z.H.; Harrison, D.J. Micromachining of capillary electrophoresis injectors and separators on glass chips and evaluation of flow at capillary intersections. Analytical Chemistry, 1994, 66(1), 177-184.
61. Johirul, M.; Shiddiky, A.; Kim, R.E.; Shim, Y.B. Microchip capillary electrophoresis with a cellulose-DNA-modified screen-printed electrode for the analysis of neurotransmitters. Electrophoresis, 2005, 26(15), 3043-3052.
62. Zhang, C.X.; Manz, A. Narrow sample channel injectors for capillary electrophoresis on microchips. Analytical Chemistry, 2001, 73(11), 2656-2662.
63. Beard, N.P.; Zhang, C.X.; de Mello, A.J. In-column field-amplified sample stacking of biogenic amines on microfabricated electrophoresis devices. Electrophoresis, 2003, 24(4), 732-739.
64. Shiddiky, M.J.A.; Park, D.S.; Shim, Y.B. Detection of polymerase chain reaction fragments using a conducting polymer-modified screen-printed electrode in a microfluidic device. Electrophoresis, 2005, 26(24), 4656-4663.
65. Shiddiky, M.J.A.; Kim, R.E.; Shim, Y.B. Microchip capillary electrophoresis with a cellulose-DNA-modified screen-printed electrode for the analysis of neurotransmitters. Electrophoresis, 2005, 26(15), 3043-3052.
66. Du, F.; Fung, Y.S. Development of CE-dual opposite carbon-fiber micro-disk electrode detection for peak purity assessment of polyphenols in red wine. Electrophoresis, 2010, 31(13), 2192-2199.
67. Shackelford, R.E.; Kaufmann, W.K.; Paules, R.S. Oxidative stress and cell cycle checkpoint function. Free Radic. Biol. Med., 2000, 28(9), 1387-1404.
68. Liu, X.; Li, Q.L.; Gong, X.C.; Li, H.M.; Chen, Z.Z.; Tong, L.L.; Tang, B. Rapid determination of superoxide free radical in hepatocellular carcinoma cells by MCE with LIF. Electrophoresis, 2009, 30(6), 1077-1083.
69. Li, H.; Li, Q.; Wang, X.; Xu, K.; Chen, Z.; Gong, X.; Liu, X.; Tong, L.; Tang, B. Simultaneous Determination of Superoxide and Hydrogen Peroxide in Macrophage RAW 264.7 Cell Extracts by Microchip Electrophoresis with Laser-Induced Fluorescence Detection. Analytical Chemistry, 2009, 81(6), 2193-2198.
70. Sun, Y.; Yin, X.F.; Ling, Y.Y.; Fang, Z.L. Determination of reactive oxygen species in single human erythrocytes using microfluidic chip electrophoresis. Analytical and Bioanalytical Chemistry, 2005, 382(7), 1472-1476.
71. Ling, Y.Y.; Yin, X.F.; Fang, Z.L. Simultaneous determination of glutathione and reactive oxygen species in individual cells by microchip electrophoresis. Electrophoresis, 2005, 26(24), 4759-4766.
72. Sun, Y.; Yin, X.F. Novel multi-depth microfluidic chip for single cell analysis. J. Chromatogr. A, 2006, 1117(2), 228-233.
73. Thomas, C.R., Chemical Engineering Problems in Biotechnology, ed. Winkler, M.A. 1990: Elsevier Applied Science, London.
74. Al-Rubeai, M.; Oh, S.K.W.; Musaheb, R.; Emery, A.N. Modified cellular metabolism in hybridomas subjected to hydrodynamic and other stresses. Biotechnology Letters, 1990, 12(5), 323-328.
75. Joshi, J.B.; Elias, C.B.; Patole, M.S. Role of hydrodynamic shear in the cultivation of animal, plant and microbial cells. The Chemical Engineering Journal and the Biochemical Engineering Journal, 1996, 62(2), 121-141.
76. Walker, G.M.; Zeringue, H.C.; Beebe, D.J. Microenvironment design considerations for cellular scale studies. Lab on a Chip-Miniaturisation for Chemistry and Biology, 2004, 4(2), 91-97.
77. Coyle, C.H.; Martinez, L.J.; Coleman, M.C.; Spitz, D.R.; Weintraub, N.L.; Kader, K.N. Mechanisms of H2O2-induced oxidative stress in endothelial cells. Free Radical Biology and Medicine, 2006, 40(12), 2206-2213.
78. [] Coyle, C.H.; Kader, K.N. Mechanisms of H2O2-Induced Oxidative Stress in Endothelial Cells Exposed to Physiologic Shear Stress. ASAIO Journal, 2007, 53(1), 17-22. Doi: 10.1097/1001.mat.0000247157.0000284350.e0000247158.
79. Davies, P.F. Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology. Nat Clin Pract Cardiovasc Med, 2009, 6(1), 16-26.
80. Han, R.B.; Yuan, Y.J. Oxidative burst in suspension culture of Taxus cuspidata induced by a laminar shear stress in short-term. Biotechnology Progress, 2004, 20(2), 507-513.
81. Chin, L.K.; Yu, J.Q.; Fu, Y.; Yu, T.; Liu, A.Q.; Luo, K.Q. Production of reactive oxygen species in endothelial cells under different pulsatile shear stresses and glucose concentrations. Lab on a Chip-Miniaturisation for Chemistry and Biology, 2011, 11(11), 1856-1863.
82. Ducret, A.; Maisonneuve, E.; Notareschi, P.; Grossi, A.; Mignot, T.; Dukan, S. A microscope automated fluidic system to study bacterial processes in real time. PLoS ONE, 2009, 4(9) 1-2.
83. Lindner, A.B.; Madden, R.; Demarez, A.; Stewart, E.J.; Taddei, F. Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105(8), 3076-3081.
84. Gao, D.; Liu, J.; Wei, H.B.; Li, H.F.; Guo, G.S.; Lin, J.M. A microfluidic approach for anticancer drug analysis based on hydrogel encapsulated tumor cells. Analytica Chimica Acta, 2010, 665(1), 7-14.
85. Mahto, S.K.; Yoon, T.H.; Shin, H.; Rhee, S.W. Multicompartmented microfluidic device for characterization of dose-dependent cadmium cytotoxicity in BALB/3T3 fibroblast cells. Biomedical Microdevices, 2009, 11(2), 401-411.
86. Mahto, S.K.; Yoon, T.H.; Rhee, S.W. A new perspective on in vitro assessment method for evaluating quantum dot toxicity by using microfluidics technology. Biomicrofluidics, 2010, 4(3), 1-8.
87. Donaldson, K.; Stone, V.; Tran, C.L.; Kreyling, W.; Borm, P.J.A. Nanotoxicology. Occupational and Environmental Medicine, 2004, 61(9), 727-728.
88. Weibel, D.B.; Whitesides, G.M. Applications of microfluidics in chemical biology. Current Opinion in Chemical Biology, 2006, 10(6), 584-591.
89. Dertinger, S.K.W.; Chiu, D.T.; Jeon, N.L.; Whitesides, G.M. Generation of Gradients Having Complex Shapes Using Microfluidic Networks. Analytical Chemistry, 2001, 73(6), 1240-1246.
90. Jeon, N.L.; Dertinger, S.K.W.; Chiu, D.T.; Choi, I.S.; Stroock, A.D.; Whitesides, G.M. Generation of Solution and Surface Gradients Using Microfluidic Systems. Langmuir, 2000, 16(22), 8311-8316.
91. Ye, N.; Qin, J.; Shi, W.; Liu, X.; Lin, B. Cell-based high content screening using an integrated microfluidic device. Lab on a Chip-Miniaturisation for Chemistry and Biology, 2007, 7(12), 1696-1704.
92. Ruan, J.; Wang, L.; Xu, M.; Cui, D.; Zhou, X.; Liu, D. Fabrication of a microfluidic chip containing dam, weirs and gradient generator for studying cellular response to chemical modulation. Materials Science and Engineering C, 2009, 29(3), 674-679.
93. Lo, J.F.; Sinkala, E.; Eddington, D.T. Oxygen gradients for open well cellular cultures via microfluidic substrates. Lab on a Chip, 2010, 10(18), 2394-2401.
94. Murphy, B.M.; Dandy, D.S.; Henry, C.S. Analysis of oxidative stress biomarkers using a simultaneous competitive/non-competitive micromosaic immunoassay. Analytica Chimica Acta, 2009, 640(1-2), 1-6.
95. Bai, H.-Y.; Lin, S.-L.; Chung, Y.-T.; Liu, T.-Y.; Chan, S.-A.; Fuh, M.-R. Quantitative determination of 8-isoprostaglandin F(2 alpha) in human urine using microfluidic chip-based nano-liquid chromatography with on-chip sample enrichment and tandem mass spectrometry. J. Chromatogr. A, 2011, 1218(15), 2085-2090.