A microfluidic approach for anticancer drug analysis based on hydrogel encapsulated tumor cells

Analytica Chimica Acta

Volumn 665, Issue 1, 2010, Pages 7-14

  Gao, Dan ^a,b   Liu, Jiangjiang ^b   Wei, Hui Bin ^b   Li, Hai Fang ^b   Guo, Guang Sheng ^a   Lin, Jin Ming ^b  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Anticancer drug; Cell encapsulation; Hydrogel microstructures; Microfluidic device

Indexed keywords

A549 CELLS; ANTICANCER DRUG; BIOMEDICAL RESEARCH; CELL ENCAPSULATIONS; CELL VIABILITY; CELL-BASED ASSAYS; ENCAPSULATED CELL; FAST METHODS; FLUORESCENCE DETECTION; GLUTATHIONES; HEPG2 CELLS; HIGH-THROUGHPUT ASSAYS; HUMAN HEPATOMAS; HUMAN LUNG; HYDROGEL MICROSTRUCTURES; INDUCED APOPTOSIS; LIVING CELL; MICRO-FLUIDIC DEVICES; NOVEL METHODS; PARALLEL DETECTION; PHOTOCROSS-LINKING; PREPOLYMERS; REACTIVE OXYGEN SPECIES; REDOX BALANCES; TUMOR CELLS;

CELL DEATH; DRUG PRODUCTS; FLUIDIC DEVICES; MICROFLUIDICS; MICROSTRUCTURE; OXYGEN; THREE DIMENSIONAL; TUMORS;

HYDROGELS;

DACTINOMYCIN; GLUTATHIONE; METHOTREXATE; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ENCAPSULATION; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG SELECTIVITY; HUMAN; HUMAN CELL; HYDROGEL; IMMOBILIZED CELL; LIVER CELL CARCINOMA; LUNG CARCINOMA; MICROFLUIDIC ANALYSIS; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; GLUTATHIONE; HEP G2 CELLS; HUMANS; HYDROGELS; MICROFLUIDIC ANALYTICAL TECHNIQUES; POLYMERS; REACTIVE OXYGEN SPECIES; TISSUE ARRAY ANALYSIS;

EID: 77951171628     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2010.03.015     Document Type: Article

References (31)

1. Wlodkowic D., Skommer J., Darzynkiewicz Z. Cytometry Part A 2008, 73A:496-507.
2. Darzynkiewicz Z., Juan G., Li X., Gorczyca W., Murakami T., Traganos F. Cytometry 1997, 27:1-20.
3. Brown J.M., Attardi L.D. Nat. Rev. Cancer 2005, 5:231-237.
4. Vilkner T., Janasek D., Manz A. Anal. Chem. 2004, 76:3373-3385.
5. McDonald J.C., Duffy D.C., Anderson J.R., Chiu D.T., Wu H., Schueller O.J., Whitesides G.M. Electrophoresis 2000, 21:27-40.
6. Jo K., Heien M.L., Thompson L.B., Zhong M., Nuzzo R.G., Sweedler J.V. Lab Chip 2007, 7:1454-1460.
7. Hufnagel H., Huebner A., Gulch C., Guse K., Abell C., Hollfelder F. Lab Chip 2009, 9:1576-1582.
8. Wheeler A.R., Throndset W.R., Whelan R.J., Leach A.M., Zare R.N., Liao Y.H., Farrell K., Manger I.D., Daridon A. Anal. Chem. 2003, 75:3581-3586.
9. Khademhosseini A., Yeh J., Jon S., Eng G., Suh K.Y., Burdick J.A., Langer R. Lab Chip 2004, 4:425-430.
10. Sasuga Y., Iwasawa T., Terada K., Oe Y., Sorimachi H., Ohara O., Harada Y. Anal. Chem. 2008, 80:9141-9149.
11. Di Carlo D., Aghdam N., Lee L.P. Anal. Chem. 2006, 78:4925-4930.
12. Matsunaga T., Hosokawa M., Arakaki A., Taguchi T., Mori T., Tanaka T., Takeyama H. Anal. Chem. 2008, 80:5139-5145.
13. Koh W.G., Itle L.J., Pishko M.V. Anal. Chem. 2003, 75:5783-5789.
14. Panda P., Ali S., Lo E., Chung B.G., Hatton T.A., Khademhosseini A., Doyle P.S. Lab Chip 2008, 8:1056-1061.
15. Albrecht D.R., Tsang V.L., Sah R.L., Bhatia S.N. Lab Chip 2005, 5:111-118.
16. Ling Y., Rubin J., Deng Y., Huang C., Demirci U., Karp J.M., Khademhosseini A. Lab Chip 2007, 7:756-762.
17. Olsen K.G., Ross D.J., Tarlov M.J. Anal. Chem. 2002, 74:1436-1441.
18. Liu J.J., Gao D., Li H.F., Lin J.M. Lab Chip 2009, 9:1301-1305.
19. Lee W., Choi D., Kim J.H., Koh W.G. Biomed. Microdevices 2008, 10:813-822.
20. Zhan W., Seong G.H., Crooks R.M. Anal. Chem. 2002, 74:4647-4652.
21. Zguris J.C., Itle L.J., Hayes D., Pishko M.V. Biomed. Microdevices 2005, 7:117-125.
22. Cruise G.M., Scharp D.S., Hubbell J.A. Biomaterials 1998, 19:1287-1294.
23. Scott R.A., Peppas N.A. Biomaterials 1999, 20:1371-1380.
24. Mellott M.B., Searcy K., Pishko M.V. Biomaterials 2001, 22:929-941.
25. Unger M.A., Chou H.P., Thorsen T., Scherer A., Quake S.R. Science 2000, 288:113-116.
26. Seong G.H., Zhan W., Crooks R.M. Anal. Chem. 2002, 74:3372-3377.
27. Dendukuri D., Panda P., Haghgooie R., Kim J.M., Hatton T.A., Doyle P.S. Macromolecules 2008, 41:8547-8556.
28. Bryant S.J., Nuttelman C.R., Anseth K.S. J. Biomater. Sci: Polym. E 2000, 11:439-457.
29. Revzin A., Russell R.J., Yadavalli V.K., Koh W.G., Deister C., Hile D.D., Mellott M.B., Pishko M.V. Langmuir 2001, 17:5440-5447.
30. Charati S.G., Stern S.A. Macromolecules 1998, 31:5529-5535.
31. Davison K., Cote S., Mader S., Miller W.H. Leukemia 2003, 17:931-940.