-
1
-
-
67651173077
-
Incretin-based therapies for type 2 diabetes mellitus
-
Lovshin J.A., Drucker D.J. Incretin-based therapies for type 2 diabetes mellitus. Nat Rev Endocrinol 2009, 5:262-269.
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 262-269
-
-
Lovshin, J.A.1
Drucker, D.J.2
-
2
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer T.J., Habener J.F. The glucagon-like peptides. Endocr Rev 1999, 20:876-913.
-
(1999)
Endocr Rev
, vol.20
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
3
-
-
0033303516
-
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
-
Hansen L., Deacon C.F., Orskov C., Holst J.J. Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine. Endocrinology 1999, 140:5356-5363.
-
(1999)
Endocrinology
, vol.140
, pp. 5356-5363
-
-
Hansen, L.1
Deacon, C.F.2
Orskov, C.3
Holst, J.J.4
-
4
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
-
Ban K., Noyan-Ashraf M.H., Hoefer J., Bolz S.S., Drucker D.J., Husain M. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008, 117:2340-2350.
-
(2008)
Circulation
, vol.117
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.S.4
Drucker, D.J.5
Husain, M.6
-
5
-
-
38149083367
-
Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart
-
Sonne D.P., Engstrøm T., Treiman M. Protective effects of GLP-1 analogues exendin-4 and GLP-1(9-36) amide against ischemia-reperfusion injury in rat heart. Regul Pept 2008, 146:243-249.
-
(2008)
Regul Pept
, vol.146
, pp. 243-249
-
-
Sonne, D.P.1
Engstrøm, T.2
Treiman, M.3
-
6
-
-
28144441354
-
Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy
-
Nikolaidis L.A., Elahi D., Shen Y.T., Shannon R.P. Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 2005, 289:H2401-H2408.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.289
-
-
Nikolaidis, L.A.1
Elahi, D.2
Shen, Y.T.3
Shannon, R.P.4
-
7
-
-
77950267745
-
Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor
-
Ban K., Kim K.H., Cho C.K., Sauvé M., Diamandis E.P., Backx P.H., Drucker D.J., Husain M. Glucagon-like peptide (GLP)-1(9-36)amide-mediated cytoprotection is blocked by exendin(9-39) yet does not require the known GLP-1 receptor. Endocrinology 2010, 151:1520-1531.
-
(2010)
Endocrinology
, vol.151
, pp. 1520-1531
-
-
Ban, K.1
Kim, K.H.2
Cho, C.K.3
Sauvé, M.4
Diamandis, E.P.5
Backx, P.H.6
Drucker, D.J.7
Husain, M.8
-
8
-
-
52049093652
-
GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP
-
Green B.D., Hand K.V., Dougan J.E., McDonnell B.M., Cassidy R.S., Grieve D.J. GLP-1 and related peptides cause concentration-dependent relaxation of rat aorta through a pathway involving KATP and cAMP. Arch Biochem Biophys 2008, 478:136-142.
-
(2008)
Arch Biochem Biophys
, vol.478
, pp. 136-142
-
-
Green, B.D.1
Hand, K.V.2
Dougan, J.E.3
McDonnell, B.M.4
Cassidy, R.S.5
Grieve, D.J.6
-
9
-
-
46249133023
-
Glucagon-like peptide-1 (9-36) amide, cleavage product of glucagon-like peptide-1 (7-36) is a glucoregulatory peptide
-
Elahi D., Egan J.M., Shannon R.P., Meneilly G.S., Khatri A., Habener J.F., Andersen D.K. Glucagon-like peptide-1 (9-36) amide, cleavage product of glucagon-like peptide-1 (7-36) is a glucoregulatory peptide. Obesity 2008, 16:1501-1509.
-
(2008)
Obesity
, vol.16
, pp. 1501-1509
-
-
Elahi, D.1
Egan, J.M.2
Shannon, R.P.3
Meneilly, G.S.4
Khatri, A.5
Habener, J.F.6
Andersen, D.K.7
-
10
-
-
66749102158
-
Clinical review: the extrapancreatic effects of glucagon-like peptide-1 and related peptides
-
Abu-Hamdah R., Rabiee A., Meneilly G.S., Shannon R.P., Andersen D.K., Elahi D. Clinical review: the extrapancreatic effects of glucagon-like peptide-1 and related peptides. J Clin Endocrinol Metab 2009, 94:1843-1852.
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1843-1852
-
-
Abu-Hamdah, R.1
Rabiee, A.2
Meneilly, G.S.3
Shannon, R.P.4
Andersen, D.K.5
Elahi, D.6
-
11
-
-
75249100556
-
Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis
-
Tomas E., Habener J.F. Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis. Trends Endocrinol Metab 2010, 21:59-67.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 59-67
-
-
Tomas, E.1
Habener, J.F.2
-
12
-
-
77955028664
-
GLP-1(9-36)amide metabolite suppression of glucose production in isolated mouse hepatocytes
-
Tomas E., Stanojevic V., Habener J.F. GLP-1(9-36)amide metabolite suppression of glucose production in isolated mouse hepatocytes. Horm Metab Res 2010, 42:657-662.
-
(2010)
Horm Metab Res
, vol.42
, pp. 657-662
-
-
Tomas, E.1
Stanojevic, V.2
Habener, J.F.3
-
13
-
-
33744945766
-
The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans
-
Meier J.J., Gethmann A., Nauck M.A., Gotze O., Schmitz F., Deacon C.F., Gallwitz B., Schmidt W.E., Holst J.J. The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans. Am J Physiol Endocrinol Metab 2006, 290:E1118-E1123.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Meier, J.J.1
Gethmann, A.2
Nauck, M.A.3
Gotze, O.4
Schmitz, F.5
Deacon, C.F.6
Gallwitz, B.7
Schmidt, W.E.8
Holst, J.J.9
-
14
-
-
78649700161
-
GLP-1(9-36)amide metabolite inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice
-
Tomas E., Wood J.A., Habener J.F. GLP-1(9-36)amide metabolite inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice. Diab Obes Metab 2011, 13:26-33.
-
(2011)
Diab Obes Metab
, vol.13
, pp. 26-33
-
-
Tomas, E.1
Wood, J.A.2
Habener, J.F.3
-
15
-
-
0029111540
-
Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides
-
Hupe-Sodmann K., McGregor G.P., Bridenbaugh R., Göke R., Göke B., Thole H., Zimmermann B., Voigt K. Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7-36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides. Regul Pept 1995, 58:149-156.
-
(1995)
Regul Pept
, vol.58
, pp. 149-156
-
-
Hupe-Sodmann, K.1
McGregor, G.P.2
Bridenbaugh, R.3
Göke, R.4
Göke, B.5
Thole, H.6
Zimmermann, B.7
Voigt, K.8
-
16
-
-
12244281855
-
Circulation and degradation of GIP and GLP-1
-
Deacon C.F. Circulation and degradation of GIP and GLP-1. Horm Metab Res 2004, 36:761-765.
-
(2004)
Horm Metab Res
, vol.36
, pp. 761-765
-
-
Deacon, C.F.1
-
17
-
-
24944436267
-
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
-
Plamboeck A., Holst J.J., Carr R.D., Deacon C.F. Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig. Diabetologia 2005, 48:1882-1890.
-
(2005)
Diabetologia
, vol.48
, pp. 1882-1890
-
-
Plamboeck, A.1
Holst, J.J.2
Carr, R.D.3
Deacon, C.F.4
-
18
-
-
79953189495
-
-
Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=15&f=G&l=50&co1=AND&d=PG01&s1=brownlee.IN.&OS=IN/brownlee&RS=IN/brownlee
-
Brownlee M. GLP-1 (9-36) methods and compositions. USPTO application number: US 2008/-194483 A1 Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=15&f=G&l=50&co1=AND&d=PG01&s1=brownlee.IN.&OS=IN/brownlee&RS=IN/brownlee. http://appft1.uspto.gov/netahtml/PTO/search-bool.html.
-
GLP-1 (9-36) methods and compositions. USPTO application number: US 2008/-194483 A1
-
-
Brownlee, M.1
-
19
-
-
73849114263
-
Towards the molecular mechanism of respiratory complex I
-
Hirst J. Towards the molecular mechanism of respiratory complex I. Biochem J 2009, 425:327-339.
-
(2009)
Biochem J
, vol.425
, pp. 327-339
-
-
Hirst, J.1
-
20
-
-
34347216368
-
Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase
-
Liu H.Y., Collins Q.F., Xiong Y., Moukdar F., Lupo E.G., Liu Z., Cao W. Prolonged treatment of primary hepatocytes with oleate induces insulin resistance through p38 mitogen-activated protein kinase. J Biol Chem May 11 2007, 282:14205-14212.
-
(2007)
J Biol Chem
, vol.282
, pp. 14205-14212
-
-
Liu, H.Y.1
Collins, Q.F.2
Xiong, Y.3
Moukdar, F.4
Lupo, E.G.5
Liu, Z.6
Cao, W.7
-
21
-
-
67049155945
-
Dissecting the role of insulin resistance in the metabolic syndrome
-
Haas J.T., Biddinger S.B. Dissecting the role of insulin resistance in the metabolic syndrome. Curr Opin Lipidol 2009, 20:206-210.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 206-210
-
-
Haas, J.T.1
Biddinger, S.B.2
-
22
-
-
46749149676
-
Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis
-
Grattagliano I., Palmieri V.O., Portincasa P., Moschetta A., Palasciano G. Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis. J Nutr Biochem 2008, 19:491-504.
-
(2008)
J Nutr Biochem
, vol.19
, pp. 491-504
-
-
Grattagliano, I.1
Palmieri, V.O.2
Portincasa, P.3
Moschetta, A.4
Palasciano, G.5
-
23
-
-
34247490186
-
Mitochondria, oxidative stress and cell death
-
Ott M., Gogvadze V., Orrenius S., Zhivotovsky B. Mitochondria, oxidative stress and cell death. Apoptosis 2007, 12:913-922.
-
(2007)
Apoptosis
, vol.12
, pp. 913-922
-
-
Ott, M.1
Gogvadze, V.2
Orrenius, S.3
Zhivotovsky, B.4
-
24
-
-
4544370680
-
Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
-
Zhao K., Zhao G.M., Wu D., Soong Y., Birk A.V., Schiller P.W., Szeto H.H. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J Biol Chem 2007, 279:34682-34690.
-
(2007)
J Biol Chem
, vol.279
, pp. 34682-34690
-
-
Zhao, K.1
Zhao, G.M.2
Wu, D.3
Soong, Y.4
Birk, A.V.5
Schiller, P.W.6
Szeto, H.H.7
-
25
-
-
72449143806
-
Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats
-
Simonsen L., Pilgaard S., Carr R.D., Kanstrup A.B., Holst J.J., Deacon C.F. Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats. Horm Metab Res 2009, 41:851-853.
-
(2009)
Horm Metab Res
, vol.41
, pp. 851-853
-
-
Simonsen, L.1
Pilgaard, S.2
Carr, R.D.3
Kanstrup, A.B.4
Holst, J.J.5
Deacon, C.F.6
-
26
-
-
36849040001
-
Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice
-
Flock G., Baggio L.L., Longuet C., Drucker J.J. Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice. Diabetes 2007, 56:3006-3013.
-
(2007)
Diabetes
, vol.56
, pp. 3006-3013
-
-
Flock, G.1
Baggio, L.L.2
Longuet, C.3
Drucker, J.J.4
-
27
-
-
33646369165
-
Cell-permeable, mitochondrial-targeted, peptide antioxidants
-
Szeto H.H. Cell-permeable, mitochondrial-targeted, peptide antioxidants. AAPS J 2006, 8:E277-E283.
-
(2006)
AAPS J
, vol.8
-
-
Szeto, H.H.1
-
28
-
-
33646256570
-
Intracellular targeting of truncated secretory peptides in the mammalian heart and brain
-
Brun C., Philip-Couderc P., Raggenbass M., Roatti A., Baertschi A.J. Intracellular targeting of truncated secretory peptides in the mammalian heart and brain. FASEB J 2006, 20:732-734.
-
(2006)
FASEB J
, vol.20
, pp. 732-734
-
-
Brun, C.1
Philip-Couderc, P.2
Raggenbass, M.3
Roatti, A.4
Baertschi, A.J.5
-
29
-
-
10044257654
-
Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria
-
Yamada H., Chounan R., Higashi Y., Kurihara N., Kido H. Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria. FEBS Lett 2004, 578:331-336.
-
(2004)
FEBS Lett
, vol.578
, pp. 331-336
-
-
Yamada, H.1
Chounan, R.2
Higashi, Y.3
Kurihara, N.4
Kido, H.5
-
30
-
-
0024317055
-
The mitochondrial targeting function of randomly generated peptide sequences correlates with predicted helical amphiphilicity
-
Lemire B.D., Frankenhauser C., Baker A., Schatz Z. The mitochondrial targeting function of randomly generated peptide sequences correlates with predicted helical amphiphilicity. J Biol Chem 1989, 264:20205-20215.
-
(1989)
J Biol Chem
, vol.264
, pp. 20205-20215
-
-
Lemire, B.D.1
Frankenhauser, C.2
Baker, A.3
Schatz, Z.4
-
31
-
-
62349096841
-
Efficient mitochondrial targeting relies on co-operation of multiple protein signals in plants
-
Chatre L., Matheson L.A., Jack A.S., Hanton S.L., Brandizzi F. Efficient mitochondrial targeting relies on co-operation of multiple protein signals in plants. J Exp Bot 2009, 60:741-749.
-
(2009)
J Exp Bot
, vol.60
, pp. 741-749
-
-
Chatre, L.1
Matheson, L.A.2
Jack, A.S.3
Hanton, S.L.4
Brandizzi, F.5
-
32
-
-
0028041313
-
Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein
-
Baldwin G.S. Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein. Proc Natl Acad Sci USA 1994, 91:7593-7597.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7593-7597
-
-
Baldwin, G.S.1
-
33
-
-
0029944132
-
A new inhibitor of mitochondrial fatty acid oxidation
-
Hashimoto T., Shindo Y., Souri M., Baldwin G.S. A new inhibitor of mitochondrial fatty acid oxidation. J Biochem 1996, 119:1196-1201.
-
(1996)
J Biochem
, vol.119
, pp. 1196-1201
-
-
Hashimoto, T.1
Shindo, Y.2
Souri, M.3
Baldwin, G.S.4
-
34
-
-
33847038835
-
A growth hormone-releasing peptide promotes mitochondrial biogenesis and a fat burning-like phenotype through scavenger receptor CD36 in white adipocytes
-
Rodrigue-Way A., Demers A., Ong H., Tremblay A. A growth hormone-releasing peptide promotes mitochondrial biogenesis and a fat burning-like phenotype through scavenger receptor CD36 in white adipocytes. Endocrinology 2007, 148:1009-1018.
-
(2007)
Endocrinology
, vol.148
, pp. 1009-1018
-
-
Rodrigue-Way, A.1
Demers, A.2
Ong, H.3
Tremblay, A.4
-
35
-
-
0032452225
-
Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35years
-
Randle P.J. Regulatory interactions between lipids and carbohydrates: the glucose fatty acid cycle after 35years. Diab Metab Rev 1998, 14:263-283.
-
(1998)
Diab Metab Rev
, vol.14
, pp. 263-283
-
-
Randle, P.J.1
-
36
-
-
73949147212
-
Insulin sensitizers in nonalcoholic fatty liver disease and steatohepatitis: current status
-
Stein L.L., Dong M.H., Loomba R. Insulin sensitizers in nonalcoholic fatty liver disease and steatohepatitis: current status. Adv Ther 2009, 26:893-907.
-
(2009)
Adv Ther
, vol.26
, pp. 893-907
-
-
Stein, L.L.1
Dong, M.H.2
Loomba, R.3
|