메뉴 건너뛰기




Volumn 43, Issue 10, 2012, Pages 2748-2756

Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia

Author keywords

HIF 1 ; hypoxia; neuroprotection; PHD; stroke

Indexed keywords

ERYTHROPOIETIN; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; VASCULOTROPIN;

EID: 84866742372     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.669598     Document Type: Article
Times cited : (60)

References (47)
  • 1
    • 30744477950 scopus 로고    scopus 로고
    • From angiogenesis to neuropathology
    • DOI 10.1038/nature04481, PII NATURE04481
    • Greenberg DA, Jin K. From angiogenesis to neuropathology. Nature. 2005;438:954-959. (Pubitemid 43093961)
    • (2005) Nature , vol.438 , Issue.7070 , pp. 954-959
    • Greenberg, D.A.1    Jin, K.2
  • 3
    • 33947581110 scopus 로고    scopus 로고
    • Hypoxia inducible factor prolyl 4-hydroxylase enzymes: Center stage in the battle against hypoxia, metabolic compromise and oxidative stress
    • DOI 10.1007/s11064-006-9268-7
    • Siddiq A, Aminova LR, Ratan RR. Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochem Res. 2007;32: 931-946. (Pubitemid 46481318)
    • (2007) Neurochemical Research , vol.32 , Issue.4-5 , pp. 931-946
    • Siddiq, A.1    Aminova, L.R.2    Ratan, R.R.3
  • 4
    • 33845666847 scopus 로고    scopus 로고
    • The phosphatidylinositol-3 kinase/akt pathway mediates vegf's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia
    • Kilic E, Kilic U, Wang Y, Bassetti CL, Marti HH, Hermann DM. The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J. 2006;20:1185-1187.
    • (2006) FASEB J , vol.20 , pp. 1185-1187
    • Kilic, E.1    Kilic, U.2    Wang, Y.3    Bassetti, C.L.4    Marti, H.H.5    Hermann, D.M.6
  • 5
    • 11244276997 scopus 로고    scopus 로고
    • VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
    • DOI 10.1093/brain/awh325
    • Wang Y, Kilic E, Kilic U, Weber B, Bassetti CL, Marti HH, et al. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain. 2005;128:52-63. (Pubitemid 40070520)
    • (2005) Brain , vol.128 , Issue.1 , pp. 52-63
    • Wang, Y.1    Kilic, E.2    Kilic, U.3    Weber, B.4    Bassetti, C.L.5    Marti, H.H.6    Hermann, D.M.7
  • 6
    • 0034368238 scopus 로고    scopus 로고
    • Neuroprotection and angiogenesis: Dual role of erythropoietin in brain ischemia
    • Marti HH, Bernaudin M, Petit E, Bauer C. Neuroprotection and angiogenesis: dual role of erythropoietin in brain ischemia. News Physiol Sci. 2000;15:225-229.
    • (2000) News Physiol Sci , vol.15 , pp. 225-229
    • Marti, H.H.1    Bernaudin, M.2    Petit, E.3    Bauer, C.4
  • 7
    • 57049145362 scopus 로고    scopus 로고
    • Brain protection by erythropoietin: A manifold task
    • Rabie T, Marti HH. Brain protection by erythropoietin: a manifold task. Physiology (Bethesda). 2008;23:263-274.
    • (2008) Physiology (Bethesda) , vol.23 , pp. 263-274
    • Rabie, T.1    Marti, H.H.2
  • 8
    • 43649093915 scopus 로고    scopus 로고
    • Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
    • DOI 10.1016/j.molcel.2008.04.009, PII S109727650800292X
    • Kaelin WG Jr., Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell. 2008;30:393-402. (Pubitemid 351681994)
    • (2008) Molecular Cell , vol.30 , Issue.4 , pp. 393-402
    • Kaelin Jr., W.G.1    Ratcliffe, P.J.2
  • 11
    • 80052404569 scopus 로고    scopus 로고
    • Impaired hypoxic response in senescent mouse brain
    • Rabie T, Kunze R, Marti HH. Impaired hypoxic response in senescent mouse brain. Int J Dev Neurosci. 2011;29:655-661.
    • (2011) Int J Dev Neurosci , vol.29 , pp. 655-661
    • Rabie, T.1    Kunze, R.2    Marti, H.H.3
  • 13
    • 34250021865 scopus 로고    scopus 로고
    • Neuron-specific inactivation of the hypoxia inducible factor 1α increases brain injury in a mouse model of transient focal cerebral ischemia
    • DOI 10.1523/JNEUROSCI.0449-07.2007
    • Baranova O, Miranda LF, Pichiule P, Dragatsis I, Johnson RS, Chavez JC. Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J Neurosci. 2007;27:6320-6332. (Pubitemid 46890035)
    • (2007) Journal of Neuroscience , vol.27 , Issue.23 , pp. 6320-6332
    • Baranova, O.1    Miranda, L.F.2    Pichiule, P.3    Dragatsis, I.4    Johnson, R.S.5    Chavez, J.C.6
  • 14
    • 78650874284 scopus 로고    scopus 로고
    • Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats
    • Nagel S, Papadakis M, Chen R, Hoyte LC, Brooks KJ, Gallichan D, et al. Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab. 2011;31:132-143.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 132-143
    • Nagel, S.1    Papadakis, M.2    Chen, R.3    Hoyte, L.C.4    Brooks, K.J.5    Gallichan, D.6
  • 15
    • 84855786346 scopus 로고    scopus 로고
    • Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1alpha
    • Ogle ME, Gu X, Espinera AR, Wei L. Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1alpha. Neurobiol Dis. 2012;45: 733-742.
    • (2012) Neurobiol Dis , vol.45 , pp. 733-742
    • Ogle, M.E.1    Gu, X.2    Espinera, A.R.3    Wei, L.4
  • 17
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain [1]
    • DOI 10.1038/5007
    • Soriano P. Generalized Lacz expression with the Rosa26 Cre reporter strain. Nat Genet. 1999;21:70-71. (Pubitemid 29036285)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 18
    • 81855211000 scopus 로고    scopus 로고
    • A transgenic approach to identify thyroxine transporter-expressing structures in brain development
    • Lang MF, Salinin S, Ridder DA, Kleesiek J, Hroudova J, Berger S, et al. A transgenic approach to identify thyroxine transporter-expressing structures in brain development. J Neuroendocrinol. 2011;23:1194-1203.
    • (2011) J Neuroendocrinol , vol.23 , pp. 1194-1203
    • Lang, M.F.1    Salinin, S.2    Ridder, D.A.3    Kleesiek, J.4    Hroudova, J.5    Berger, S.6
  • 19
    • 79953179377 scopus 로고    scopus 로고
    • Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury
    • Holscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, et al. Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J Biol Chem. 2011;286: 11185-11194.
    • (2011) J Biol Chem , vol.286 , pp. 11185-11194
    • Holscher, M.1    Silter, M.2    Krull, S.3    Von Ahlen, M.4    Hesse, A.5    Schwartz, P.6
  • 20
    • 77951552411 scopus 로고    scopus 로고
    • Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury
    • Hyvarinen J, Hassinen IE, Sormunen R, Maki JM, Kivirikko KI, Koivunen P, et al. Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury. J Biol Chem. 2010;285:13646-13657.
    • (2010) J Biol Chem , vol.285 , pp. 13646-13657
    • Hyvarinen, J.1    Hassinen, I.E.2    Sormunen, R.3    Maki, J.M.4    Kivirikko, K.I.5    Koivunen, P.6
  • 21
    • 47649128513 scopus 로고    scopus 로고
    • Hypoxiainducible factor-1 is central to cardioprotection: A new paradigm for ischemic preconditioning
    • Eckle T, Kohler D, Lehmann R, El Kasmi K, Eltzschig HK. Hypoxiainducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning. Circulation. 2008;118:166-175.
    • (2008) Circulation , vol.118 , pp. 166-175
    • Eckle, T.1    Kohler, D.2    Lehmann, R.3    El Kasmi, K.4    Eltzschig, H.K.5
  • 22
    • 33750976389 scopus 로고    scopus 로고
    • Placental but not heart defects are associated with elevated hypoxia-inducible factor α levels in mice lacking prolyl hydroxylase domain protein 2
    • DOI 10.1128/MCB.00425-06
    • Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A, Fong GH. Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. Mol Cell Biol. 2006;26:8336-8346. (Pubitemid 44748568)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.22 , pp. 8336-8346
    • Takeda, K.1    Ho, V.C.2    Takeda, H.3    Duan, L.-J.4    Nagy, A.5    Fong, G.-H.6
  • 23
    • 65649105473 scopus 로고    scopus 로고
    • Hif-prolyl hydroxylases in the rat kidney: Physiologic expression patterns and regulation in acute kidney injury
    • Schodel J, Klanke B, Weidemann A, Buchholz B, Bernhardt W, Bertog M, et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol. 2009;174:1663-1674.
    • (2009) Am J Pathol , vol.174 , pp. 1663-1674
    • Schodel, J.1    Klanke, B.2    Weidemann, A.3    Buchholz, B.4    Bernhardt, W.5    Bertog, M.6
  • 24
    • 0033624837 scopus 로고    scopus 로고
    • CaMKIIα-cre transgene expression and recombination patterns in the mouse brain
    • DOI 10.1002/(SICI)1526-968X(200002)26:2<133::AID-GENE10>3.0.CO;2-V
    • Dragatsis I, Zeitlin S. CamKIIalpha-Cre transgene expression and recombination patterns in the mouse brain. Genesis. 2000;26:133-135. (Pubitemid 30158098)
    • (2000) Genesis , vol.26 , Issue.2 , pp. 133-135
    • Dragatsis, I.1    Zeitlin, S.2
  • 25
    • 33744954065 scopus 로고    scopus 로고
    • Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: The role of HIF-1α, HIF-2α, and other pathways
    • DOI 10.1074/jbc.M511408200
    • Elvidge GP, Glenny L, Appelhoff RJ, Ratcliffe PJ, Ragoussis J, Gleadle JM. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate- dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem. 2006;281:15215-15226. (Pubitemid 43855111)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.22 , pp. 15215-15226
    • Elvidge, G.P.1    Glenny, L.2    Appelhoff, R.J.3    Ratcliffe, P.J.4    Ragoussis, J.5    Gleadle, J.M.6
  • 29
    • 82755162954 scopus 로고    scopus 로고
    • Regulation of cellular levels of sprouty2 protein by prolyl hydroxylase domain and von hippel-lindau proteins
    • Anderson K, Nordquist KA, Gao X, Hicks KC, Zhai B, Gygi SP, et al. Regulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteins. J Biol Chem. 2011;286: 42027-42036.
    • (2011) J Biol Chem , vol.286 , pp. 42027-42036
    • Anderson, K.1    Nordquist, K.A.2    Gao, X.3    Hicks, K.C.4    Zhai, B.5    Gygi, S.P.6
  • 30
    • 69249137859 scopus 로고    scopus 로고
    • Hypoxia-inducible factor prolyl-4-hydroxylase phd2 protein abundance depends on integral membrane anchoring of fkbp38
    • Barth S, Edlich F, Berchner-Pfannschmidt U, Gneuss S, Jahreis G, Hasgall PA, et al. Hypoxia-inducible factor prolyl-4-hydroxylase Phd2 protein abundance depends on integral membrane anchoring of FKBP38. J Biol Chem. 2009;284:23046-23058.
    • (2009) J Biol Chem , vol.284 , pp. 23046-23058
    • Barth, S.1    Edlich, F.2    Berchner-Pfannschmidt, U.3    Gneuss, S.4    Jahreis, G.5    Hasgall, P.A.6
  • 33
    • 33645735151 scopus 로고    scopus 로고
    • The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha
    • Dayan F, Roux D, Brahimi-Horn MC, Pouyssegur J, Mazure NM. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha. Cancer Res. 2006;66: 3688-3698.
    • (2006) Cancer Res , vol.66 , pp. 3688-3698
    • Dayan, F.1    Roux, D.2    Brahimi-Horn, M.C.3    Pouyssegur, J.4    Mazure, N.M.5
  • 34
    • 1642315195 scopus 로고    scopus 로고
    • Catalytic Properties of the Asparaginyl Hydroxylase (FIH) in the Oxygen Sensing Pathway Are Distinct from Those of Its Prolyl 4-Hydroxylases
    • DOI 10.1074/jbc.M312254200
    • Koivunen P, Hirsila M, Gunzler V, Kivirikko KI, Myllyharju J. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases. J Biol Chem. 2004;279:9899-9904. (Pubitemid 38372589)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.11 , pp. 9899-9904
    • Koivunen, P.1    Hirsila, M.2    Gunzler, V.3    Kivirikko, K.I.4    Myllyharju, J.5
  • 35
    • 33747366672 scopus 로고    scopus 로고
    • Cell-specific regulation of hypoxia-inducible factor (hif)-1alpha and hif-2alpha stabilization and transactivation in a graded oxygen environment
    • Bracken CP, Fedele AO, Linke S, Balrak W, Lisy K, Whitelaw ML, et al. Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment. J Biol Chem. 2006;281:22575-22585.
    • (2006) J Biol Chem , vol.281 , pp. 22575-22585
    • Bracken, C.P.1    Fedele, A.O.2    Linke, S.3    Balrak, W.4    Lisy, K.5    Whitelaw, M.L.6
  • 36
    • 36548998930 scopus 로고    scopus 로고
    • Contribution of hif-1alpha or hif-2alpha to erythropoietin expression: In vivo evidence based on chromatin immunoprecipitation
    • Yeo EJ, Cho YS, Kim MS, Park JW. Contribution of HIF-1alpha or HIF-2alpha to erythropoietin expression: in vivo evidence based on chromatin immunoprecipitation. Ann Hematol. 2008;87:11-17.
    • (2008) Ann Hematol , vol.87 , pp. 11-17
    • Yeo, E.J.1    Cho, Y.S.2    Kim, M.S.3    Park, J.W.4
  • 37
    • 84455192443 scopus 로고    scopus 로고
    • General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain
    • Tanaka T, Kai S, Koyama T, Daijo H, Adachi T, Fukuda K, et al. General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain. PLoS One. 2011;6:e29378.
    • (2011) PLoS One , vol.6
    • Tanaka, T.1    Kai, S.2    Koyama, T.3    Daijo, H.4    Adachi, T.5    Fukuda, K.6
  • 45
    • 33747660292 scopus 로고    scopus 로고
    • Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels: Evidence for an autoregulatory oxygen-sensing system
    • DOI 10.1074/jbc.M601719200
    • Stiehl DP, Wirthner R, Koditz J, Spielmann P, Camenisch G, Wenger RH. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system. J Biol Chem. 2006;281:23482-23491. (Pubitemid 44274123)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.33 , pp. 23482-23491
    • Stiehl, D.P.1    Wirthner, R.2    Koditz, J.3    Spielmann, P.4    Camenisch, G.5    Wenger, R.H.6
  • 47
    • 70449519416 scopus 로고    scopus 로고
    • Non-hypoxic stabilization of hypoxia-inducible factor alpha (hif-alpha): Relevance in neural progenitor/stem cells
    • Milosevic J, Adler I, Manaenko A, Schwarz SC, Walkinshaw G, Arend M, et al. Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells. Neurotox Res. 2009;15:367-380.
    • (2009) Neurotox Res , vol.15 , pp. 367-380
    • Milosevic, J.1    Adler, I.2    Manaenko, A.3    Schwarz, S.C.4    Walkinshaw, G.5    Arend, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.