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Volumn 66, Issue 5, 2012, Pages 375-382

Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets

Author keywords

Grape extract; Microbiota; Nutraceuticals; Phamacokinetics; Red wine; Resveratrol

Indexed keywords

DIHYDRORESVERATROL GLUCURONIDE; DRUG METABOLITE; GRAPE EXTRACT; NUTRACEUTICAL; PICEID; RESVERASOR; RESVERATROL; RESVERATROL GLUCOSIDE; UNCLASSIFIED DRUG;

EID: 84866740513     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.08.001     Document Type: Article
Times cited : (153)

References (61)
  • 1
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • J.A. Baur, and D.A. Sinclair Therapeutic potential of resveratrol: the in vivo evidence Nature Reviews Drug Discovery 5 6 2006 493 506
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 2
    • 0345487505 scopus 로고    scopus 로고
    • Alcohol and mortality in middle-aged men from eastern France
    • S.C. Renaud, R. Gueguen, J. Schenker, and A. d'Houtaud Alcohol and mortality in middle-aged men from eastern France Epidemiology 9 2 1998 184 188
    • (1998) Epidemiology , vol.9 , Issue.2 , pp. 184-188
    • Renaud, S.C.1    Gueguen, R.2    Schenker, J.3    D'Houtaud, A.4
  • 3
    • 84860276621 scopus 로고    scopus 로고
    • High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients
    • R. Zamora-Ros, M. Urpi-Sarda, R.M. Lamuela-Raventos, M.A. Martinez-Gonzalez, J. Salas-Salvado, and F. Aros High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients Pharmacological Research 65 6 2012 615 620
    • (2012) Pharmacological Research , vol.65 , Issue.6 , pp. 615-620
    • Zamora-Ros, R.1    Urpi-Sarda, M.2    Lamuela-Raventos, R.M.3    Martinez-Gonzalez, M.A.4    Salas-Salvado, J.5    Aros, F.6
  • 4
    • 84860295083 scopus 로고    scopus 로고
    • Intake of alcohol-free red wine modulates antioxidant enzyme activities in a human intervention study
    • M.A. Noguer, A.B. Cerezo, N.E. Donoso, and M.C. Garcia-Parrilla Intake of alcohol-free red wine modulates antioxidant enzyme activities in a human intervention study Pharmacological Research 65 6 2012 609 614
    • (2012) Pharmacological Research , vol.65 , Issue.6 , pp. 609-614
    • Noguer, M.A.1    Cerezo, A.B.2    Donoso, N.E.3    Garcia-Parrilla, M.C.4
  • 6
    • 84860290833 scopus 로고    scopus 로고
    • Colorectal cancer chemoprevention by trans-resveratrol
    • M.E. Juan, I. Alfaras, and J.M. Planas Colorectal cancer chemoprevention by trans-resveratrol Pharmacological Research 65 6 2012 584 591
    • (2012) Pharmacological Research , vol.65 , Issue.6 , pp. 584-591
    • Juan, M.E.1    Alfaras, I.2    Planas, J.M.3
  • 7
    • 51349132313 scopus 로고    scopus 로고
    • Cancer chemopreventive and therapeutic potential of resveratrol: Mechanistic perspectives
    • J.K. Kundu, and Y.J. Surh Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives Cancer Letters 269 2 2008 243 261
    • (2008) Cancer Letters , vol.269 , Issue.2 , pp. 243-261
    • Kundu, J.K.1    Surh, Y.J.2
  • 8
    • 33747286388 scopus 로고    scopus 로고
    • Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets
    • C. Ramassamy Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets European Journal of Pharmacology 545 1 2006 51 64
    • (2006) European Journal of Pharmacology , vol.545 , Issue.1 , pp. 51-64
    • Ramassamy, C.1
  • 9
    • 84855853383 scopus 로고    scopus 로고
    • Resveratrol, a neuroprotective supplement for Alzheimer's disease
    • F. Li, Q. Gong, H. Dong, and J. Shi Resveratrol, a neuroprotective supplement for Alzheimer's disease Current Pharmaceutical Design 18 1 2012 27 33
    • (2012) Current Pharmaceutical Design , vol.18 , Issue.1 , pp. 27-33
    • Li, F.1    Gong, Q.2    Dong, H.3    Shi, J.4
  • 10
    • 80054991836 scopus 로고    scopus 로고
    • Dietary phytochemicals and their potential effects on obesity: A review
    • M. Gonzalez-Castejon, and A. Rodriguez-Casado Dietary phytochemicals and their potential effects on obesity: a review Pharmacological Research 64 5 2011 438 455
    • (2011) Pharmacological Research , vol.64 , Issue.5 , pp. 438-455
    • Gonzalez-Castejon, M.1    Rodriguez-Casado, A.2
  • 11
    • 0141719702 scopus 로고    scopus 로고
    • Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
    • K.T. Howitz, K.J. Bitterman, H.Y. Cohen, D.W. Lamming, S. Lavu, and J.G. Wood Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature 425 6954 2003 191 196
    • (2003) Nature , vol.425 , Issue.6954 , pp. 191-196
    • Howitz, K.T.1    Bitterman, K.J.2    Cohen, H.Y.3    Lamming, D.W.4    Lavu, S.5    Wood, J.G.6
  • 12
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • J.A. Baur, K.J. Pearson, N.L. Price, H.A. Jamieson, C. Lerin, and A. Kalra Resveratrol improves health and survival of mice on a high-calorie diet Nature 444 7117 2006 337 342
    • (2006) Nature , vol.444 , Issue.7117 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3    Jamieson, H.A.4    Lerin, C.5    Kalra, A.6
  • 13
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • J.G. Wood, B. Rogina, S. Lavu, K. Howitz, S.L. Helfand, and M. Tatar Sirtuin activators mimic caloric restriction and delay ageing in metazoans Nature 430 7000 2004 686 689
    • (2004) Nature , vol.430 , Issue.7000 , pp. 686-689
    • Wood, J.G.1    Rogina, B.2    Lavu, S.3    Howitz, K.4    Helfand, S.L.5    Tatar, M.6
  • 18
    • 70350764804 scopus 로고    scopus 로고
    • Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells
    • M. Miksits, K. Wlcek, M. Svoboda, O. Kunert, E. Haslinger, and T. Thalhammer Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells Planta Medica 75 11 2009 1227 1230
    • (2009) Planta Medica , vol.75 , Issue.11 , pp. 1227-1230
    • Miksits, M.1    Wlcek, K.2    Svoboda, M.3    Kunert, O.4    Haslinger, E.5    Thalhammer, T.6
  • 22
    • 0037248470 scopus 로고    scopus 로고
    • Absorption of three wine-related polyphenols in three different matrices by healthy subjects
    • D.M. Goldberg, J. Yan, and G.J. Soleas Absorption of three wine-related polyphenols in three different matrices by healthy subjects Clinical Biochemistry 36 1 2003 79 87
    • (2003) Clinical Biochemistry , vol.36 , Issue.1 , pp. 79-87
    • Goldberg, D.M.1    Yan, J.2    Soleas, G.J.3
  • 23
    • 0035811176 scopus 로고    scopus 로고
    • Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection
    • G.J. Soleas, J. Yan, and D.M. Goldberg Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection Journal of Chromatography. B, Biomedical Sciences and Applications 757 1 2001 161 172
    • (2001) Journal of Chromatography. B, Biomedical Sciences and Applications , vol.757 , Issue.1 , pp. 161-172
    • Soleas, G.J.1    Yan, J.2    Goldberg, D.M.3
  • 24
    • 1242336775 scopus 로고    scopus 로고
    • Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice
    • X. Meng, P. Maliakal, H. Lu, M.J. Lee, and C.S. Yang Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice Journal of Agricultural and Food Chemistry 52 4 2004 935 942
    • (2004) Journal of Agricultural and Food Chemistry , vol.52 , Issue.4 , pp. 935-942
    • Meng, X.1    Maliakal, P.2    Lu, H.3    Lee, M.J.4    Yang, C.S.5
  • 26
    • 18844372768 scopus 로고    scopus 로고
    • Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry
    • M. Urpi-Sarda, O. Jauregui, R.M. Lamuela-Raventos, W. Jaeger, M. Miksits, and M.I. Covas Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry Analytical Chemistry 77 10 2005 3149 3155
    • (2005) Analytical Chemistry , vol.77 , Issue.10 , pp. 3149-3155
    • Urpi-Sarda, M.1    Jauregui, O.2    Lamuela-Raventos, R.M.3    Jaeger, W.4    Miksits, M.5    Covas, M.I.6
  • 30
    • 48649106985 scopus 로고    scopus 로고
    • Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - Two novel resveratrol metabolites in human plasma
    • A. Burkon, and V. Somoza Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O- conjugated diglucuronides - two novel resveratrol metabolites in human plasma Molecular Nutrition & Food Research 52 5 2008 549 557
    • (2008) Molecular Nutrition & Food Research , vol.52 , Issue.5 , pp. 549-557
    • Burkon, A.1    Somoza, V.2
  • 34
    • 77953353711 scopus 로고    scopus 로고
    • Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects
    • C. la Porte, N. Voduc, G. Zhang, I. Seguin, D. Tardiff, and N. Singhal Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects Clinical Pharmacokinetics 49 7 2010 449 454
    • (2010) Clinical Pharmacokinetics , vol.49 , Issue.7 , pp. 449-454
    • La Porte, C.1    Voduc, N.2    Zhang, G.3    Seguin, I.4    Tardiff, D.5    Singhal, N.6
  • 35
    • 53049095375 scopus 로고    scopus 로고
    • Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort
    • R. Zamora-Ros, C. Andres-Lacueva, R.M. Lamuela-Raventos, T. Berenguer, P. Jakszyn, and C. Martinez Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort British Journal of Nutrition 100 1 2008 188 196
    • (2008) British Journal of Nutrition , vol.100 , Issue.1 , pp. 188-196
    • Zamora-Ros, R.1    Andres-Lacueva, C.2    Lamuela-Raventos, R.M.3    Berenguer, T.4    Jakszyn, P.5    Martinez, C.6
  • 39
    • 0035398717 scopus 로고    scopus 로고
    • Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake
    • E. Miro-Casas, A.M. Farre, M.I. Covas, J.O. Rodriguez, C.E. Menoyo, and R.M. Lamuela Raventos Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intake Analytical Biochemistry 294 1 2001 63 72
    • (2001) Analytical Biochemistry , vol.294 , Issue.1 , pp. 63-72
    • Miro-Casas, E.1    Farre, A.M.2    Covas, M.I.3    Rodriguez, J.O.4    Menoyo, C.E.5    Lamuela Raventos, R.M.6
  • 41
    • 33750600920 scopus 로고    scopus 로고
    • Increased transport of resveratrol across monolayers of the human intestinal Caco-2 cells is mediated by inhibition and saturation of metabolites
    • A. Maier-Salamon, B. Hagenauer, M. Wirth, F. Gabor, T. Szekeres, and W. Jager Increased transport of resveratrol across monolayers of the human intestinal Caco-2 cells is mediated by inhibition and saturation of metabolites Pharmaceutical Research 23 9 2006 2107 2115
    • (2006) Pharmaceutical Research , vol.23 , Issue.9 , pp. 2107-2115
    • Maier-Salamon, A.1    Hagenauer, B.2    Wirth, M.3    Gabor, F.4    Szekeres, T.5    Jager, W.6
  • 42
    • 80054014686 scopus 로고    scopus 로고
    • Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats
    • I.M. Kapetanovic, M. Muzzio, Z. Huang, T.N. Thompson, and D.L. McCormick Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats Cancer Chemotherapy and Pharmacology 68 3 2011 593 601
    • (2011) Cancer Chemotherapy and Pharmacology , vol.68 , Issue.3 , pp. 593-601
    • Kapetanovic, I.M.1    Muzzio, M.2    Huang, Z.3    Thompson, T.N.4    McCormick, D.L.5
  • 43
    • 33751108964 scopus 로고    scopus 로고
    • Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection
    • C. Lv, L. Zhang, Q. Wang, W. Liu, C. Wang, and X. Jing Determination of piceid in rat plasma and tissues by high-performance liquid chromatographic method with UV detection Biomedical Chromatography 20 11 2006 1260 1266
    • (2006) Biomedical Chromatography , vol.20 , Issue.11 , pp. 1260-1266
    • Lv, C.1    Zhang, L.2    Wang, Q.3    Liu, W.4    Wang, C.5    Jing, X.6
  • 44
    • 34250765283 scopus 로고    scopus 로고
    • Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection
    • M. Zhou, X. Chen, and D. Zhong Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 854 1-2 2007 219 223
    • (2007) Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences , vol.854 , Issue.12 , pp. 219-223
    • Zhou, M.1    Chen, X.2    Zhong, D.3
  • 49
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • E. Wenzel, and V. Somoza Metabolism and bioavailability of trans-resveratrol Molecular Nutrition & Food Research 49 5 2005 472 481
    • (2005) Molecular Nutrition & Food Research , vol.49 , Issue.5 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 52
    • 13244277948 scopus 로고    scopus 로고
    • Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells
    • C. Henry, X. Vitrac, A. Decendit, R. Ennamany, S. Krisa, and J.M. Merillon Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells Journal of Agricultural and Food Chemistry 53 3 2005 798 803
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , Issue.3 , pp. 798-803
    • Henry, C.1    Vitrac, X.2    Decendit, A.3    Ennamany, R.4    Krisa, S.5    Merillon, J.M.6
  • 54
    • 0032915558 scopus 로고    scopus 로고
    • Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans
    • T. Miyazawa, K. Nakagawa, M. Kudo, K. Muraishi, and K. Someya Direct intestinal absorption of red fruit anthocyanins, cyanidin-3-glucoside and cyanidin-3,5-diglucoside, into rats and humans Journal of Agricultural and Food Chemistry 47 3 1999 1083 1091
    • (1999) Journal of Agricultural and Food Chemistry , vol.47 , Issue.3 , pp. 1083-1091
    • Miyazawa, T.1    Nakagawa, K.2    Kudo, M.3    Muraishi, K.4    Someya, K.5
  • 58
    • 33947186284 scopus 로고    scopus 로고
    • Metabolic diversity of the intestinal microbiota: Implications for health and disease
    • M. Blaut, and T. Clavel Metabolic diversity of the intestinal microbiota: implications for health and disease Journal of Nutrition 137 3 Suppl. 2 2007 751S 755S
    • (2007) Journal of Nutrition , vol.137 , Issue.SUPPL. 2
    • Blaut, M.1    Clavel, T.2
  • 60
    • 79960768800 scopus 로고    scopus 로고
    • New delivery systems to improve the bioavailability of resveratrol
    • A.C. Santos, F. Veiga, and A.J. Ribeiro New delivery systems to improve the bioavailability of resveratrol Expert Opinion on Drug Delivery 8 8 2011 973 990
    • (2011) Expert Opinion on Drug Delivery , vol.8 , Issue.8 , pp. 973-990
    • Santos, A.C.1    Veiga, F.2    Ribeiro, A.J.3
  • 61
    • 84858709095 scopus 로고    scopus 로고
    • Administration of resveratrol: What formulation solutions to bioavailability limitations?
    • A. Amri, J.C. Chaumeil, S. Sfar, and C. Charrueau Administration of resveratrol: what formulation solutions to bioavailability limitations? Journal of Controlled Release 158 2 2012 182 193
    • (2012) Journal of Controlled Release , vol.158 , Issue.2 , pp. 182-193
    • Amri, A.1    Chaumeil, J.C.2    Sfar, S.3    Charrueau, C.4


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