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Volumn 8, Issue 8, 2011, Pages 973-990

New delivery systems to improve the bioavailability of resveratrol

Author keywords

Bioavailability; New delivery systems; Pharmacokinetics; Resveratrol; Stability

Indexed keywords

ACOUSTICALLY ACTIVE LIPOSPHERE; ASIALOFETUIN; CHITOSAN; CYCLODEXTRIN; DIHYDRORESVERATROL; DRUG CARRIER; DRUG METABOLITE; GELATIN; GLYCOPROTEIN; IMMUNOGLOBULIN; LIPOSOME; MELANIN; MICROSPHERE; NANOPARTICLE; NANOSPHERE; PHENOL DERIVATIVE; PICEID; RESVERATROL; RESVERATROL 3 O 4' O DISULFATE; RESVERATROL 3 O GLUCOSIDE; RESVERATROL 3 O GLUCURONIDE; RESVERATROL 3 O SULFATE; RESVERATROL 3 SULFATE; RESVERATROL 3,4' DISULFATE; RESVERATROL 3,5 DISULFATE; RESVERATROL 4 O GLUCOSIDE; RESVERATROL 4' O GLUCURONIDE; RESVERATROL 4' O SULFATE; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG;

EID: 79960768800     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2011.581655     Document Type: Review
Times cited : (107)

References (98)
  • 1
    • 36749081135 scopus 로고    scopus 로고
    • Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications
    • DOI 10.1042/BST0351156
    • de la Lastra CA, Villegas I. Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications. Biochem Soc Trans 2007;35(5):1156-60 (Pubitemid 350206449)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1156-1160
    • Alarcon De La Lastra, C.1    Villegas, I.2
  • 2
    • 0242695672 scopus 로고    scopus 로고
    • Resveratrol: From grapevines to mammalian biology
    • DOI 10.1096/fj.03-0168rev
    • Pervaiz S. Resveratrol: from grapevines to mammalian biology. FASEB J 2003;17(14):1975-85 (Pubitemid 37392442)
    • (2003) FASEB Journal , vol.17 , Issue.14 , pp. 1975-1985
    • Pervaiz, S.1
  • 3
    • 70349325730 scopus 로고    scopus 로고
    • Improvements of cellular stress response on resveratrol in liposomes
    • Kristl J, Teskac K, Caddeo C, et al. Improvements of cellular stress response on resveratrol in liposomes. Eur J Pharm Biopharm 2009;73(2):253-9
    • (2009) Eur. J. Pharm. Biopharm. , vol.73 , Issue.2 , pp. 253-259
    • Kristl, J.1    Teskac, K.2    Caddeo, C.3
  • 4
    • 73049096477 scopus 로고    scopus 로고
    • Antioxidant properties of resveratrol: A structure-activity insight
    • Gulcin I. Antioxidant properties of resveratrol: A structure-activity insight. Innovat Food Sci Emerg Tech 2010;11(1):210-18
    • (2010) Innovat. Food Sci. Emerg. Tech. , vol.11 , Issue.1 , pp. 210-218
    • Gulcin, I.1
  • 5
    • 76449086773 scopus 로고    scopus 로고
    • Preformulation stability of trans-resveratrol and trans-resveratrol glucoside piceid
    • Jensen J, Wertz C, O'Neill V. Preformulation stability of trans-resveratrol and trans-resveratrol glucoside (Piceid). J Agric Food Chem 2010;58(3):1685-90
    • (2010) J. Agric. Food Chem. , vol.58 , Issue.3 , pp. 1685-1690
    • Jensen, J.1    Wertz, C.2    O'Neill, V.3
  • 6
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • DOI 10.1038/nrd2060, PII NRD2060
    • Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006;5(6):493-506 (Pubitemid 44136961)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.6 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 7
    • 48649106985 scopus 로고    scopus 로고
    • Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - Two novel resveratrol metabolites in human plasma
    • Burkon A, Somoza V. Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O- conjugated diglucuronides - two novel resveratrol metabolites in human plasma. Mol Nutr Food Res 2008;52(5):549-57
    • (2008) Mol. Nutr. Food Res. , vol.52 , Issue.5 , pp. 549-557
    • Burkon, A.1    Somoza, V.2
  • 8
    • 37349092988 scopus 로고    scopus 로고
    • Stabilization and encapsulation of photosensitive resveratrol within yeast cell
    • DOI 10.1016/j.ijpharm.2007.07.044, PII S0378517307006497
    • Shi G, Rao L, Yu H, et al. Stabilization and encapsulation of photosensitive resveratrol within yeast cell. Int J Pharm 2008;349(1-2):83-93 (Pubitemid 350299698)
    • (2008) International Journal of Pharmaceutics , vol.349 , Issue.1-2 , pp. 83-93
    • Shi, G.1    Rao, L.2    Yu, H.3    Xiang, H.4    Yang, H.5    Ji, R.6
  • 9
    • 79954627959 scopus 로고    scopus 로고
    • Resveratrol: A multifunctional cytoprotective molecule
    • Juhasz B, Varga B, Gesztelyi R, et al. Resveratrol: a multifunctional cytoprotective molecule. Curr Pharm Biotechnol 2010;11(8):810-18
    • (2010) Curr. Pharm. Biotechnol. , vol.11 , Issue.8 , pp. 810-818
    • Juhasz, B.1    Varga, B.2    Gesztelyi, R.3
  • 10
    • 77951782384 scopus 로고    scopus 로고
    • Current therapeutic targets for the treatment of Alzheimers disease
    • Grill JD, Cummings JL. Current therapeutic targets for the treatment of Alzheimer's disease. Expert Rev Neurother 2010;10(5):711-28
    • (2010) Expert. Rev. Neurother. , vol.10 , Issue.5 , pp. 711-728
    • Grill, J.D.1    Cummings, J.L.2
  • 11
    • 77955088481 scopus 로고    scopus 로고
    • Resveratrol as a therapeutic agent for neurodegenerative diseases
    • Sun AY, Wang Q, Simonyi A, et al. Resveratrol as a Therapeutic Agent for Neurodegenerative Diseases. Mol Neurobiol 2010;41(2-3):375-83
    • (2010) Mol. Neurobiol. , vol.41 , Issue.2-3 , pp. 375-383
    • Sun, A.Y.1    Wang, Q.2    Simonyi, A.3
  • 12
    • 77954090603 scopus 로고    scopus 로고
    • Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma
    • Gatouillat G, Balasse E, Joseph-Pietras D, et al. Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma. J Cell Biochem 2010;110(4):893-902
    • (2010) J. Cell Biochem. , vol.110 , Issue.4 , pp. 893-902
    • Gatouillat, G.1    Balasse, E.2    Joseph-Pietras, D.3
  • 13
    • 78650399854 scopus 로고    scopus 로고
    • Resveratrol: Challenges in translation to the clinic - A critical discussion
    • Subramanian L, Youssef S, Bhattacharya S. Resveratrol: challenges in translation to the clinic - a critical discussion. Clin Cancer Res 2010;16(24):5942-8
    • (2010) Clin. Cancer Res. , vol.16 , Issue.24 , pp. 5942-5948
    • Subramanian, L.1    Youssef, S.2    Bhattacharya, S.3
  • 14
    • 77954363244 scopus 로고    scopus 로고
    • The cardiovascular nutrapharmacology of resveratrol: Pharmacokinetics molecular mechanisms and therapeutic potential
    • Kroon PA, Iyer A, Chunduri P, et al. The cardiovascular nutrapharmacology of resveratrol: pharmacokinetics, molecular mechanisms and therapeutic potential. Curr Med Chem 2010;17(23):2442-55
    • (2010) Curr. Med. Chem. , vol.17 , Issue.23 , pp. 2442-2255
    • Kroon, P.A.1    Iyer, A.2    Chunduri, P.3
  • 15
    • 79960828569 scopus 로고    scopus 로고
    • Treatment of an animal model for multiple sclerosis with resveratrol a natural compound in red wine
    • Tsunoda I, Rose JW, Rojas M, et al. Treatment of an animal model for multiple sclerosis with resveratrol, a natural compound in red wine. J Neuroimmunol 2008;203(2):247
    • (2008) J. Neuroimmunol. , vol.203 , Issue.2 , pp. 247
    • Tsunoda, I.1    Rose, J.W.2    Rojas, M.3
  • 16
    • 77950820267 scopus 로고    scopus 로고
    • Resveratrol suppresses colitis and colon cancer associated with colitis
    • Cui X, Jin Y, Hofseth AB, et al. Resveratrol suppresses colitis and colon cancer associated with colitis. Cancer Prev Res (Phila Pa) 2010;3(4):549-59
    • (2010) Cancer Prev. Res. Phila. Pa. , vol.3 , Issue.4 , pp. 549-559
    • Cui, X.1    Jin, Y.2    Hofseth, A.B.3
  • 17
    • 70350655954 scopus 로고    scopus 로고
    • Protective effect of resveratrol in severe acute pancreatitis-induced brain injury
    • Jha RK, Ma Q, Sha H, et al. Protective effect of resveratrol in severe acute pancreatitis-induced brain injury. Pancreas 2009;38(8):947-53
    • (2009) Pancreas , vol.38 , Issue.8 , pp. 947-953
    • Jha, R.K.1    Ma, Q.2    Sha, H.3
  • 18
    • 67649999248 scopus 로고    scopus 로고
    • Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers
    • Almeida L, Vaz-da-Silva M, Falcao A, et al. Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers. Mol Nutr Food Res 2009;53(1):7-15
    • (2009) Mol. Nutr. Food Res. , vol.53 , Issue.1 , pp. 7-15
    • Almeida, L.1    Vaz-Da-Silva, M.2    Falcao, A.3
  • 19
    • 67349274374 scopus 로고    scopus 로고
    • Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress
    • Lu X, Ji C, Xu H, et al. Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress. Int J Pharm 2009;37(1-2):89-96
    • (2009) Int. J. Pharm. , vol.37 , Issue.1-2 , pp. 89-96
    • Lu, X.1    Ji, C.2    Xu, H.3
  • 20
    • 51649128211 scopus 로고    scopus 로고
    • Effect of resveratrol incorporated in liposomes on proliferation and UV-B protection of cells
    • Caddeo C, Teskac K, Sinico C, et al. Effect of resveratrol incorporated in liposomes on proliferation and UV-B protection of cells. Int J Pharm 2008;363(1-2):183-91
    • (2008) Int. J. Pharm. , vol.363 , Issue.1-2 , pp. 183-191
    • Caddeo, C.1    Teskac, K.2    Sinico, C.3
  • 21
    • 70449120704 scopus 로고    scopus 로고
    • Complexation of pinosylvin an analogue of resveratrol with high antifungal and antimicrobial activity by different types of cyclodextrins
    • Lopez-Nicolas JM, Rodriguez-Bonilla P, Garcia-Caramona F. Complexation of Pinosylvin, an analogue of resveratrol with high antifungal and antimicrobial activity, by different types of cyclodextrins. J Agric Food Chem 2009;57(21):10175-80
    • (2009) J. Agric. Food Chem. , vol.57 , Issue.21 , pp. 10175-10180
    • Lopez-Nicolas, J.M.1    Rodriguez-Bonilla, P.2    Garcia-Caramona, F.3
  • 22
    • 79960767092 scopus 로고    scopus 로고
    • Resveratrol: Marcador biologic I dietetic de consum de vi
    • Ros RZ. Resveratrol: marcador biologic I dietetic de consum de vi. Barcelona: 2008
    • (2008) Barcelona
    • Ros, R.Z.1
  • 23
    • 13244277948 scopus 로고    scopus 로고
    • Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells
    • DOI 10.1021/jf048909e
    • Henry C, Vitrac X, Decendit A, et al. Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells. J Agric Food Chem 2005;53(3):798-803 (Pubitemid 40194406)
    • (2005) Journal of Agricultural and Food Chemistry , vol.53 , Issue.3 , pp. 798-803
    • Henry, C.1    Vitrac, X.2    Decendit, A.3    Ennamany, R.4    Krisa, S.5    Merillon, J.-M.6
  • 26
    • 53849145999 scopus 로고    scopus 로고
    • The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol
    • Das S, Lin HS, Ho PC, et al. The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol. Pharm Res 2008;25(11):2593-600
    • (2008) Pharm. Res. , vol.25 , Issue.11 , pp. 2593-2600
    • Das, S.1    Lin, H.S.2    Ho, P.C.3
  • 27
    • 80054689357 scopus 로고    scopus 로고
    • Pharmacokinetics oral bioavailability and metabolic profile of resveratrol and its dimethylether analog pterostilbene in rats
    • 20 Nov Epub ahead of print]
    • Kapetanovic IM, Muzzio M, Huang Z, et al. Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats. Cancer Chemother Pharmacol 20 Nov 2010; [Epub ahead of print]
    • (2010) Cancer Chemother. Pharmacol.
    • Kapetanovic, I.M.1    Muzzio, M.2    Huang, Z.3
  • 28
    • 34250765283 scopus 로고    scopus 로고
    • Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection
    • DOI 10.1016/j.jchromb.2007.04.025, PII S1570023207003224
    • Zhou M, Chen X, Zhong D. Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection. J Chromatogr B Analyt Technol Biomed Life Sci 2007;854(1-2):219-23 (Pubitemid 46962386)
    • (2007) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.854 , Issue.1-2 , pp. 219-223
    • Zhou, M.1    Chen, X.2    Zhong, D.3
  • 29
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • DOI 10.1002/mnfr.200500010
    • Wenzel E, Somoza V. Metabolism and bioavailability of trans-resveratrol. Mol Nutr Food Res 2005;49(5):472-81 (Pubitemid 40780394)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.5 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 31
    • 0036082463 scopus 로고    scopus 로고
    • Metabolism and disposition of resveratrol in rats: Extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model
    • DOI 10.1124/jpet.102.033340
    • Marier JF, Vachon P, Gritsas A, et al. Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model. J Pharmacol Exp Ther 2002;302(1):369-73 (Pubitemid 34680460)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.302 , Issue.1 , pp. 369-373
    • Marier, J.-F.1    Vachon, P.2    Gritsas, A.3    Zhang, J.4    Moreau, J.-P.5    Ducharme, M.P.6
  • 33
    • 75049085079 scopus 로고    scopus 로고
    • Matrix effects on the bioavailability of resveratrol in humans
    • Ortuno J, Covas MI, Farre M, et al. Matrix effects on the bioavailability of resveratrol in humans. Food Chem 2010;120(4):1123-30
    • (2010) Food Chem. , vol.120 , Issue.4 , pp. 1123-1130
    • Ortuno, J.1    Covas, M.I.2    Farre, M.3
  • 34
    • 18844372768 scopus 로고    scopus 로고
    • Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry
    • DOI 10.1021/ac0484272
    • Urpi-Sarda M, Jauregui O, Lamuela-Raventos RM, et al. Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry. Anal Chem 2005;77(10):3149-55 (Pubitemid 40695470)
    • (2005) Analytical Chemistry , vol.77 , Issue.10 , pp. 3149-3155
    • Urpi-Sarda, M.1    Jauregui, O.2    Lamuela-Raventos, R.M.3    Jaeger, W.4    Miksits, M.5    Covas, M.-I.6    Andres-Lacueva, C.7
  • 39
    • 20344371723 scopus 로고    scopus 로고
    • Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats
    • DOI 10.1002/mnfr.200500003
    • Wenzel E, Soldo T, Erbersdobler H, et al. Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats. Mol Nutr Food Res 2005;49(5):482-94 (Pubitemid 40780395)
    • (2005) Molecular Nutrition and Food Research , vol.49 , Issue.5 , pp. 482-494
    • Wenzel, E.1    Soldo, T.2    Erbersdobler, H.3    Somoza, V.4
  • 41
    • 33644854620 scopus 로고    scopus 로고
    • Comparative studies of the antioxidant effects of cis- and trans-resveratrol
    • Orallo F. Comparative studies of the antioxidant effects of cis- and trans-resveratrol. Curr Med Chem 2006;13(1):87-98
    • (2006) Curr. Med. Chem. , vol.13 , Issue.1 , pp. 87-98
    • Orallo, F.1
  • 42
    • 0142243190 scopus 로고    scopus 로고
    • Relationship between Mechanisms, Bioavailibility, and Preclinical Chemopreventive Efficacy of Resveratrol: A Conundrum
    • Gescher AJ, Steward WP. Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum. Cancer Epidemiol Biomarkers Prev 2003;12(10):953-7 (Pubitemid 37310248)
    • (2003) Cancer Epidemiology Biomarkers and Prevention , vol.12 , Issue.10 , pp. 953-957
    • Gescher, A.J.1    Steward, W.P.2
  • 44
    • 47349090618 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells
    • DOI 10.1021/jf800175a
    • Juan ME, Wenzel U, Daniel H, et al. Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells. J Agric Food Chem 2008;56(12):4813-18 (Pubitemid 351999415)
    • (2008) Journal of Agricultural and Food Chemistry , vol.56 , Issue.12 , pp. 4813-4818
    • Juan, M.E.1    Wenzel, U.2    Daniel, H.3    Planas, J.M.4
  • 45
    • 67349189553 scopus 로고    scopus 로고
    • Resveratrol a unique phytoalexin present in red wine delivers either survival signal or death signal to the ischemic myocardium depending on dose
    • Dudley J, Das S, Mukherjee S, et al. Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose. J Nutr Biochem 2009;20(6):443-52
    • (2009) J. Nutr. Biochem. , vol.20 , Issue.6 , pp. 443-452
    • Dudley, J.1    Das, S.2    Mukherjee, S.3
  • 47
    • 70350348642 scopus 로고    scopus 로고
    • To scale or not to scale: The principles of dose extrapolation
    • Sharma V, McNeill JH. To scale or not to scale: the principles of dose extrapolation. Br J Pharmacol 2009;157(6):907-21
    • (2009) Br. J. Pharmacol. , vol.157 , Issue.6 , pp. 907-921
    • Sharma, V.1    McNeill, J.H.2
  • 49
    • 67349182678 scopus 로고    scopus 로고
    • Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: The predimed study
    • Zamora-Ros R, Urpi-Sarda M, Lamuela-Raventos RM, et al. Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: the PREDIMED study. Free Radic Biol Med 2009;46(12):1561
    • (2009) Free Radic. Biol. Med. , vol.46 , Issue.12 , pp. 1561
    • Zamora-Ros, R.1    Urpi-Sarda, M.2    Lamuela-Raventos, R.M.3
  • 50
    • 76449115494 scopus 로고    scopus 로고
    • Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery
    • Suri S, Liu XH, Rayment S, et al. Quercetin and its major metabolites selectively modulate cyclic GMP-dependent relaxations and associated tolerance in pig isolated coronary artery. Br J Pharmacol 2010;159(3):566-75
    • (2010) Br. J. Pharmacol. , vol.159 , Issue.3 , pp. 566-575
    • Suri, S.1    Liu, X.H.2    Rayment, S.3
  • 51
    • 39449137141 scopus 로고    scopus 로고
    • Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells
    • DOI 10.1016/j.atherosclerosis.2007.07.040, PII S0021915007004832
    • Tribolo S, Lodi F, Connor C, et al. Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells. Atherosclerosis 2008;197(1):50-6 (Pubitemid 351273272)
    • (2008) Atherosclerosis , vol.197 , Issue.1 , pp. 50-56
    • Tribolo, S.1    Lodi, F.2    Connor, C.3    Suri, S.4    Wilson, V.G.5    Taylor, M.A.6    Needs, P.W.7    Kroon, P.A.8    Hughes, D.A.9
  • 52
    • 77649189281 scopus 로고    scopus 로고
    • Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells
    • Shu XH, Li H, Sun Z, et al. Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells. Biochem Pharmacol 2010;79(10):1516-25
    • (2010) Biochem. Pharmacol. , vol.79 , Issue.10 , pp. 1516-1525
    • Shu, X.H.1    Li, H.2    Sun, Z.3
  • 53
    • 70350764804 scopus 로고    scopus 로고
    • Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells
    • Miksits M, Wlcek K, Svoboda M, et al. Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells. Planta Med 2009;75(11):1227-30
    • (2009) Planta. Med. , vol.75 , Issue.11 , pp. 1227-1230
    • Miksits, M.1    Wlcek, K.2    Svoboda, M.3
  • 54
    • 4844223990 scopus 로고    scopus 로고
    • Resveratrol glucuronides as the metabolites of resveratrol in humans: Characterization, synthesis, and anti-HIV activity
    • DOI 10.1002/jps.20156
    • Wang LX, Heredia A, Song H, et al. Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity. J Pharm Sci 2004;93(10):2448-57 (Pubitemid 39319429)
    • (2004) Journal of Pharmaceutical Sciences , vol.93 , Issue.10 , pp. 2448-2457
    • Wang, L.-X.1    Heredia, A.2    Song, H.3    Zhang, Z.4    Yu, B.5    Davis, C.6    Redfield, R.7
  • 55
    • 75849141782 scopus 로고    scopus 로고
    • A theoretical study of the structure-radical scavenging activity of trans-resveratrol analogues and cis-resveratrol in gas phase and water environment
    • Mikulski D, Gorniak R, Molski M. A theoretical study of the structure-radical scavenging activity of trans-resveratrol analogues and cis-resveratrol in gas phase and water environment. Eur J Med Chem 2010;45(3):1015-27
    • (2010) Eur. J. Med. Chem. , vol.45 , Issue.3 , pp. 1015-1027
    • Mikulski, D.1    Gorniak, R.2    Molski, M.3
  • 58
    • 0041825750 scopus 로고    scopus 로고
    • Glycosylation of resveratrol protects it from enzymic oxidation
    • DOI 10.1042/BJ20030141
    • Regev-Shoshani G, Shoseyov O, Bilkis I, et al. Glycosylation of resveratrol protects it from enzymatic oxidation. Biochem J 2003;374(Pt 1):157-63 (Pubitemid 37046939)
    • (2003) Biochemical Journal , vol.374 , Issue.1 , pp. 157-163
    • Regev-Shoshani, G.1    Shoseyov, O.2    Bilkis, I.3    Kerem, Z.4
  • 59
    • 73449100838 scopus 로고    scopus 로고
    • Resveratrol: Its biologic targets and functional activity
    • Pervaiz S, Holme AL. Resveratrol: its biologic targets and functional activity. Antioxid Redox Signal 2009;11(11):2851-97
    • (2009) Antioxid. Redox .Signal , vol.11 , Issue.11 , pp. 2851-2897
    • Pervaiz, S.1    Holme, A.L.2
  • 60
    • 37549016731 scopus 로고    scopus 로고
    • Commentary: Bioavailability of flavonoids and polyphenols: Call to rms
    • Hu M. Commentary: bioavailability of flavonoids and polyphenols: call to arms. Mol Pharm 2007;4(6):803-6
    • (2007) Mol. Pharm. , vol.4 , Issue.6 , pp. 803-806
    • Hu, M.1
  • 61
    • 78049461954 scopus 로고    scopus 로고
    • Transglutaminase: New insights into gelatin nanoparticle cross-linking
    • Fuchs S, Kutscher M, Hertel T, et al. Transglutaminase: new insights into gelatin nanoparticle cross-linking. J Microencapsul 2010;27(8):747-54
    • (2010) J. Microencapsul. , vol.27 , Issue.8 , pp. 747-754
    • Fuchs, S.1    Kutscher, M.2    Hertel, T.3
  • 62
    • 77649273978 scopus 로고    scopus 로고
    • Novel biodegradable chitosan-gelatin/ nano-bioactive glass ceramic composite scaffolds for alveolar bone tissue engineering
    • Peter M, Binulal NS, Nair SV, et al. Novel biodegradable chitosan-gelatin/ nano-bioactive glass ceramic composite scaffolds for alveolar bone tissue engineering. Chem Eng J 2010;158(2):353-61
    • (2010) Chem. Eng. J. , vol.158 , Issue.2 , pp. 353-361
    • Peter, M.1    Binulal, N.S.2    Nair, S.V.3
  • 63
    • 67349116528 scopus 로고    scopus 로고
    • Solubilization of resveratrol in micellar solutions of different bile acids
    • Atanackovic M, Posa M, Heinle H, et al. Solubilization of resveratrol in micellar solutions of different bile acids. Colloids Surf B Biointerfaces 2009;72(1):148-54
    • (2009) Colloids Surf. B Biointerfaces. , vol.72 , Issue.1 , pp. 148-154
    • Atanackovic, M.1    Posa, M.2    Heinle, H.3
  • 64
    • 33645034817 scopus 로고    scopus 로고
    • Nanoencapsulation I methods for preparation of drug-loaded polymeric nanoparticles
    • Pinto Reis C, Neufeld RJ, Ribeiro AJ, et al. Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine 2006;2(1):8-21
    • (2006) Nanomedicine , vol.2 , Issue.1 , pp. 8-21
    • Pinto Reis, C.1    Neufeld, R.J.2    Ribeiro, A.J.3
  • 65
    • 77950857708 scopus 로고    scopus 로고
    • Food microencapsulation of bioactive compounds: Rheological and thermal characterisation of non-conventional gelling system
    • Borgogna M, Bellich B, Zorzin L, et al. Food microencapsulation of bioactive compounds: Rheological and thermal characterisation of non-conventional gelling system. Food Chem 2010;122(2):416-23
    • (2010) Food Chem. , vol.122 , Issue.2 , pp. 416-423
    • Borgogna, M.1    Bellich, B.2    Zorzin, L.3
  • 67
    • 24944541868 scopus 로고    scopus 로고
    • Stabilization of resveratrol immobilized in monodisperse cyano-functionalized porous polymeric microspheres
    • DOI 10.1016/j.polymer.2005.07.016, PII S0032386105010098
    • Nam J-B, Ryu J-H, Kim J-W, et al. Stabilization of resveratrol immobilized in monodisperse cyano-functionalized porous polymeric microspheres. Polymer (Guildf) 2005;46(21):8956-63 (Pubitemid 41328574)
    • (2005) Polymer , vol.46 , Issue.21 , pp. 8956-8963
    • Nam, J.-B.1    Ryu, J.-H.2    Kim, J.-W.3    Chang, I.-S.4    Suh, K.-D.5
  • 68
    • 72149114076 scopus 로고    scopus 로고
    • Colon-specific delivery of resveratrol: Optimization of multi-particulate calcium-pectinate carrier
    • Das S, Ng KY. Colon-specific delivery of resveratrol: Optimization of multi-particulate calcium-pectinate carrier. Int J Pharm 2009;385(1-2):20-8
    • (2009) Int. J. Pharm. , vol.385 , Issue.1-2 , pp. 20-28
    • Das, S.1    Ng, K.Y.2
  • 69
    • 75749121776 scopus 로고    scopus 로고
    • Vanillin cross-linked chitosan microspheres for controlled release of resveratrol
    • Peng H, Xiong H, Li J, et al. Vanillin cross-linked chitosan microspheres for controlled release of resveratrol. Food Chem 2010;121(1):23-8
    • (2010) Food Chem. , vol.121 , Issue.1 , pp. 23-28
    • Peng, H.1    Xiong, H.2    Li, J.3
  • 70
    • 52949148946 scopus 로고    scopus 로고
    • Complexation of resveratrol with cyclodextrins: Solubility and antioxidant activity
    • Lu Z, Cheng B, Hu Y, et al. Complexation of resveratrol with cyclodextrins: Solubility and antioxidant activity. Food Chem 2009;113(1):17-20
    • (2009) Food Chem. , vol.113 , Issue.1 , pp. 17-20
    • Lu, Z.1    Cheng, B.2    Hu, Y.3
  • 71
    • 67349197868 scopus 로고    scopus 로고
    • Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels
    • Shao J, Li X, Lu X, et al. Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels. Colloids Surf B Biointerfaces 2009;72(1):40-7
    • (2009) Colloids Surf. B Biointerfaces. , vol.72 , Issue.1 , pp. 40-47
    • Shao, J.1    Li, X.2    Lu, X.3
  • 72
    • 77951256976 scopus 로고    scopus 로고
    • The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol
    • Teskac K, Kristl J. The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol. Int J Pharm 2010;390(1):61-9
    • (2010) Int. J. Pharm. , vol.390 , Issue.1 , pp. 61-69
    • Teskac, K.1    Kristl, J.2
  • 73
    • 34250843816 scopus 로고    scopus 로고
    • A study of the formulation design of acoustically active lipospheres as carriers for drug delivery
    • Fang JY, Hung CF, Liao MH, et al. A study of the formulation design of acoustically active lipospheres as carriers for drug delivery. Eur J Pharm Biopharm 2007;67(1):67-75
    • (2007) Eur. J. Pharm. Biopharm. , vol.67 , Issue.1 , pp. 67-75
    • Fang, J.Y.1    Hung, C.F.2    Liao, M.H.3
  • 74
    • 34547601983 scopus 로고    scopus 로고
    • Nanomedicine in the diagnosis and therapy of neurodegenerative disorders
    • DOI 10.1016/j.progpolymsci.2007.05.014, PII S0079670007000743, Polymers in Biomedical Applications
    • Kabanov AV, Gendelman HE. Nanomedicine in the diagnosis and therapy of neurodegenerative disorders. Prog Polym Sci 2007;32(8-9):1054-82 (Pubitemid 47198293)
    • (2007) Progress in Polymer Science (Oxford) , vol.32 , Issue.8-9 , pp. 1054-1082
    • Kabanov, A.V.1    Gendelman, H.E.2
  • 75
    • 69049097132 scopus 로고    scopus 로고
    • Development of epigallocatechin gallate-eluting polymeric stent and its physicochemical biomechanical and biological evaluations
    • 044104 Available online at: Last accessed 18 May]
    • Han DW, Lee JJ, Jung DY, et al. Development of epigallocatechin gallate-eluting polymeric stent and its physicochemical, biomechanical and biological evaluations. Biomed Mater 2009;4(4):044104 Available online at: http://iopscience.iop.org/1748-605X/4/4/044104 [Last accessed 18 May]
    • (2009) Biomed. Mater. , vol.4 , pp. 4
    • Han, D.W.1    Lee, J.J.2    Jung, D.Y.3
  • 76
    • 58149196381 scopus 로고    scopus 로고
    • Nanoparticles enhance per oral bioavailability of poorly available molecules: Epigallocatechin gallate nanoparticles ameliorates cyclosporine induced nephrotoxicity in rats at three times lower dose than oral solution
    • Italia JL, Datta P, Ankola DD, et al. Nanoparticles enhance per oral bioavailability of poorly available molecules: epigallocatechin gallate nanoparticles ameliorates cyclosporine induced nephrotoxicity in rats at three times lower dose than oral solution. J Biomed Nanotechnol 2008;4(3):304-12
    • (2008) J. Biomed. Nanotechnol. , vol.4 , Issue.3 , pp. 304-312
    • Italia, J.L.1    Datta, P.2    Ankola, D.D.3
  • 77
    • 53649097113 scopus 로고    scopus 로고
    • Synthesis of novel biodegradable and self-assembling methoxy poly ethylene glycol-palmitate nanocarrier for curcumin delivery to cancer cells
    • Sahu A, Bora U, Kasoju N, et al. Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)-palmitate nanocarrier for curcumin delivery to cancer cells. Acta Biomater 2008;4(6):1752-61
    • (2008) Acta. Biomater. , vol.4 , Issue.6 , pp. 1752-1761
    • Sahu, A.1    Bora, U.2    Kasoju, N.3
  • 78
    • 45849083928 scopus 로고    scopus 로고
    • Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells
    • Thangapazham RL, Puri A, Tele S, et al. Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells. Int J Oncol 2008;32(5):1119-23
    • (2008) Int. J. Oncol. , vol.32 , Issue.5 , pp. 1119-1123
    • Thangapazham, R.L.1    Puri, A.2    Tele, S.3
  • 79
    • 75149122722 scopus 로고    scopus 로고
    • Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells
    • Das RK, Kasoju N, Bora U. Encapsulation of curcumin in alginate-chitosan-pluronic composite nanoparticles for delivery to cancer cells. Nanomedicine 2010;6(1):153-60
    • (2010) Nanomedicine , vol.6 , Issue.1 , pp. 153-160
    • Das, R.K.1    Kasoju, N.2    Bora, U.3
  • 80
    • 72149099632 scopus 로고    scopus 로고
    • Curcumin-loaded poly epsiloncaprolactone nanofibres: Diabetic wound dressing with anti-oxidant and anti-inflammatory properties
    • Merrell JG, McLaughlin SW, Tie L, et al. Curcumin-loaded poly(epsiloncaprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties. Clin Exp Pharmacol Physiol 2009;36(12):1149-56
    • (2009) Clin. Exp. Pharmacol. Physiol. , vol.36 , Issue.12 , pp. 1149-1156
    • Merrell, J.G.1    McLaughlin, S.W.2    Tie, L.3
  • 81
    • 67649876052 scopus 로고    scopus 로고
    • Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1
    • Li J, Wang Y, Yang C, et al. Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1. Mol Pharmacol 2009;76(1):81-90
    • (2009) Mol. Pharmacol. , vol.76 , Issue.1 , pp. 81-90
    • Li, J.1    Wang, Y.2    Yang, C.3
  • 82
    • 0037409984 scopus 로고    scopus 로고
    • Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)-poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles
    • DOI 10.1016/S0142-9612(03)00021-8
    • Hu Y, Jiang X, Ding Y, et al. Preparation and drug release behaviors of nimodipine-loaded poly(caprolactone)- poly(ethylene oxide)-polylactide amphiphilic copolymer nanoparticles. Biomaterials 2003;24(13):2395-404 (Pubitemid 36434059)
    • (2003) Biomaterials , vol.24 , Issue.13 , pp. 2395-2404
    • Hu, Y.1    Jiang, X.2    Ding, Y.3    Zhang, L.4    Yang, C.5    Zhang, J.6    Chen, J.7    Yang, Y.8
  • 83
    • 1842525951 scopus 로고    scopus 로고
    • Camptothecin derivative-loaded poly(caprolactone-co-lactide)-b-PEG-b- poly(caprolactone-co-lactide) nanoparticles and their biodistribution in mice
    • DOI 10.1016/j.jconrel.2004.01.010, PII S0168365904000343
    • Zhang L, Hu Y, Jiang X, et al. Camptothecin derivative-loaded poly (caprolactone-co-lactide)-b-PEG-b-poly (caprolactone-co-lactide) nanoparticles and their biodistribution in mice. J Control Release 2004;96(1):135-48 (Pubitemid 38438496)
    • (2004) Journal of Controlled Release , vol.96 , Issue.1 , pp. 135-148
    • Zhang, L.1    Hu, Y.2    Jiang, X.3    Yang, C.4    Lu, W.5    Yang, Y.H.6
  • 84
    • 66149107051 scopus 로고    scopus 로고
    • Liposome encapsulation of curcumin and resveratrol in combinationreduces prostate cancer incidence in PTEN knockout mice
    • Narayanan NK, Nargi D, Randolph C, et al. Liposome encapsulation of curcumin and resveratrol in combinationreduces prostate cancer incidence in PTEN knockout mice. Int J Cancer 2009;125(1):1-8
    • (2009) Int. J. Cancer , vol.125 , Issue.1 , pp. 1-8
    • Narayanan, N.K.1    Nargi, D.2    Randolph, C.3
  • 85
    • 77953032816 scopus 로고    scopus 로고
    • Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: A double-blind placebo-controlled crossover investigation
    • Kennedy DO, Wightman EL, Reay JL, et al. Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. Am J for Clin Nutr 2010;91(6):1590-7
    • (2010) Am. J. for Clin. Nutr. , vol.91 , Issue.6 , pp. 1590-1597
    • Kennedy, D.O.1    Wightman, E.L.2    Reay, J.L.3
  • 86
    • 79953007953 scopus 로고    scopus 로고
    • Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells
    • Liao PC, Ng LT, Lin LT, et al. Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells. J Med Food 2010;13(6):1415-23
    • (2010) J. Med. Food , vol.13 , Issue.6 , pp. 1415-1423
    • Liao, P.C.1    Ng, L.T.2    Lin, L.T.3
  • 87
    • 78851472360 scopus 로고    scopus 로고
    • Resveratrol modulates astroglial functions: Neuroprotective hypothesis
    • Quincozes-Santos A, Gottfried C. Resveratrol modulates astroglial functions: neuroprotective hypothesis. Ann NY Acad Sci 2011;1215(1):72-8
    • (2011) Ann. N.Y. Acad. Sci. , vol.1215 , Issue.1 , pp. 72-78
    • Quincozes-Santos, A.1    Gottfried, C.2
  • 88
    • 68149150584 scopus 로고    scopus 로고
    • Resveratrol Improves endothelial function: Role of TNF alpha and vascular oxidative stress
    • Zhang H, Zhang J, Ungvari Z. Resveratrol Improves endothelial function: role of TNF{alpha} and vascular oxidative stress. Arterioscler Thromb Vasc Biol 2009;29(8):1164-71
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , Issue.8 , pp. 1164-1171
    • Zhang, H.1    Zhang, J.2    Ungvari, Z.3
  • 90
    • 77953741269 scopus 로고    scopus 로고
    • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
    • Ungvari Z, Bagi Z, Feher A, et al. Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 2010;299(1):H18-24
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.299 , Issue.1
    • Ungvari, Z.1    Bagi, Z.2    Feher, A.3
  • 91
    • 1242336775 scopus 로고    scopus 로고
    • Urinary and plasma levels of resveratrol and quercetin in humans mice and rats after ingestion of pure compounds and grape juice
    • Meng X, Maliakal P, Lu H, et al. Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice. J Agric Food Chem 2004;52(4):935-42
    • (2004) J. Agric. Food Chem. , vol.52 , Issue.4 , pp. 935-942
    • Meng, X.1    Maliakal, P.2    Lu, H.3
  • 92
    • 0035811176 scopus 로고    scopus 로고
    • Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection
    • DOI 10.1016/S0378-4347(01)00142-6, PII S0378434701001426
    • Soleas GJ, Yan J, Goldberg DM. Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection. J Chromatogr B Biomed Sci Appl 2001;757(1):161-72 (Pubitemid 32424469)
    • (2001) Journal of Chromatography B: Biomedical Sciences and Applications , vol.757 , Issue.1 , pp. 161-172
    • Soleas, G.J.1    Yan, J.2    Goldberg, D.M.3
  • 93
    • 0034981157 scopus 로고    scopus 로고
    • Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection
    • DOI 10.1016/S0076-6879(01)35238-2
    • Soleas GJ, Yan J, Goldberg DM. Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection. Methods Enzymol 2001;335:130-45 (Pubitemid 32507233)
    • (2001) Methods in Enzymology , vol.335 , pp. 130-145
    • Soleas, G.J.1    Yan, J.2    Goldberg, D.M.3
  • 94
    • 0037248470 scopus 로고    scopus 로고
    • Absorption of three wine-related polyphenols in three different matrices by healthy subjects
    • DOI 10.1016/S0009-9120(02)00397-1
    • Goldberg DM, Yan J, Soleas GJ. Absorption of three wine-related polyphenols in three different matrices by healthy subjects. Clin Biochem 2003;36(1):79-87 (Pubitemid 36126394)
    • (2003) Clinical Biochemistry , vol.36 , Issue.1 , pp. 79-87
    • Goldberg, D.M.1    Yan, J.2    Soleas, G.J.3
  • 95
    • 77953353711 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol ethanol in healthy human subjects
    • la Porte C, Voduc N, Zhang G, et al. Steady-state pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Clinic Pharmacokinet 2010;49(7):449-54
    • (2010) Clinic Pharmacokinet , vol.49 , Issue.7 , pp. 449-454
    • La Porte, C.1    Voduc, N.2    Zhang, G.3
  • 97
    • 79960822020 scopus 로고    scopus 로고
    • Resveratrol/ cyclodextrin compound-containing water soluble complex eg for treating inflammation is prepared by adding cyclodextrin organic solvent and resveratrol compound heating cooling and separating crystal
    • Arigony Souto A. Resveratrol/ cyclodextrin compound-containing water soluble complex e.g. for treating inflammation is prepared by adding cyclodextrin, organic solvent and resveratrol compound, heating, cooling and separating crystal. Eurofarma Lab Ltda; Uniao Brasileira Educacao E Assistencia Mantenedora Da Pucrs; Uniao Brasileira Educacao E Assistenci. 2009
    • (2009) Eurofarma Lab Ltda; Uniao Brasileira Educacao E Assistencia Mantenedora Da Pucrs; Uniao Brasileira Educacao E Assistenci
    • Arigony Souto, A.1


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