D-amino acid oxidase-induced oxidative stress, 3-bromopyruvate and Citrate inhibit angiogenesis, exhibiting potent anticancer effects

Journal of Bioenergetics and Biomembranes

Volumn 44, Issue 5, 2012, Pages 513-523

  El Sayed, S M ^a   Abou El Magd, R M ^a   Shishido, Y ^a   Yorita, K ^a   Chung, S P ^a   Tran, D H ^a   Sakai, T ^a   Watanabe, H ^a   Kagami, S ^a   Fukui, K ^a,b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

3 bromopyruvate; Angiogenesis; Citrate; D amino acid oxidase; Glioblastoma; Glycolysis double inhibition

Indexed keywords

ANTINEOPLASTIC AGENT; BROMOPYRUVIC ACID; CISPLATIN; CITRIC ACID; CYTARABINE; DEXTRO AMINO ACID OXIDASE; DEXTRO PROLINE; DEXTRO SERINE; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GLIOMA CELL; GLYCOLYSIS; HUMAN; HUMAN CELL; OXIDATIVE STRESS; OXIDATIVE STRESS ENERGY DEPLETION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHELATING AGENTS; CISPLATIN; CITRIC ACID; CYTARABINE; D-AMINO-ACID OXIDASE; DRUG RESISTANCE, NEOPLASM; ENERGY METABOLISM; ENZYME INHIBITORS; GLIOBLASTOMA; HEXOKINASE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; MICE; NEOVASCULARIZATION, PATHOLOGIC; OXIDATIVE STRESS; PYRUVATES;

EID: 84866645248     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-012-9455-y     Document Type: Article

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