메뉴 건너뛰기




Volumn 24, Issue 7, 2010, Pages 1055-1067

The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia

Author keywords

D amino acid oxidase; D serine; NMDA receptors; Risperidone

Indexed keywords

DEXTRO AMINO ACID OXIDASE; RISPERIDONE;

EID: 77953755583     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881109102644     Document Type: Article
Times cited : (42)

References (73)
  • 1
    • 0036166661 scopus 로고    scopus 로고
    • Brain, plasma and tissue pharmacokinetics of risperidone and 9-hydroxyrisperidone after separate oral administration to rats
    • Berl
    • Aravagiri, M., Marder, SR (2002) Brain, plasma and tissue pharmacokinetics of risperidone and 9-hydroxyrisperidone after separate oral administration to rats. Psychopharmacology (Berl) 159: 424-431.
    • (2002) Psychopharmacology , vol.159 , pp. 424-431
    • Aravagiri, M.1    Marder, S.R.2
  • 3
    • 0021051818 scopus 로고
    • Sodium-dependent transport of phosphate in LLC-PKI cells
    • Biber, J., Brown, CD, Murer, H. (1983) Sodium-dependent transport of phosphate in LLC-PKI cells. Biochim Biophys Acta 735: 325-330.
    • (1983) Biochim Biophys Acta , vol.735 , pp. 325-330
    • Biber, J.1    Brown, C.D.2    Murer, H.3
  • 4
    • 0028789388 scopus 로고
    • Risperidone in the treatment of negative symptoms of schizophrenia: A meta-analysis
    • Carman, J., Peuskens, J., Vangeneugden, A. (1995) Risperidone in the treatment of negative symptoms of schizophrenia: a meta-analysis. Int Clin Psychopharmacol 10: 207-213.
    • (1995) Int Clin Psychopharmacol , vol.10 , pp. 207-213
    • Carman, J.1    Peuskens, J.2    Vangeneugden, A.3
  • 5
    • 0037108758 scopus 로고    scopus 로고
    • Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia
    • Chumakov, I., Blumenfeld, M., Guerassimenko, O., Cavarec, L., Palicio, M., Abderrahim, H., et al. (2002) Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc Natl Acad Sci U S A 99: 13365-13367.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13365-13367
    • Chumakov, I.1    Blumenfeld, M.2    Guerassimenko, O.3    Cavarec, L.4    Palicio, M.5    Abderrahim, H.6
  • 6
    • 0025228762 scopus 로고
    • D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia
    • Contreras, PC (1990) D-serine antagonized phencyclidine- and MK-801-induced stereotyped behavior and ataxia. Neuropharmacology 29: 291-293.
    • (1990) Neuropharmacology , vol.29 , pp. 291-293
    • Contreras, P.C.1
  • 7
    • 33750043500 scopus 로고    scopus 로고
    • Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9
    • Cunningham, TJ, Maciejewski, J., Yao, L. (2006) Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9. J Neuroinflammation 3: 25.
    • (2006) J Neuroinflammation , vol.3 , pp. 25
    • Cunningham, T.J.1    MacIejewski, J.2    Yao, L.3
  • 8
    • 34249275309 scopus 로고    scopus 로고
    • Efficacy, safety and early response of paliperidone extendedrelease tablets (paliperidone ER): Results of a 6-week, randomized, placebo-controlled study
    • Davidson, M., Emsley, R., Kramer, M., Ford, L., Pan, G., Lim, P., et al. (2007) Efficacy, safety and early response of paliperidone extendedrelease tablets (paliperidone ER). Results of a 6-week, randomized, placebo-controlled study. Schizophr Res 93: 117-130.
    • (2007) Schizophr Res , vol.93 , pp. 117-130
    • Davidson, M.1    Emsley, R.2    Kramer, M.3    Ford, L.4    Pan, G.5    Lim, P.6
  • 9
    • 0000509456 scopus 로고    scopus 로고
    • Drugs as substrates of metabolic enzymes: Antipsychotics
    • Levy, RH, Thummel, KE, Trager, WF, Hansten, PD, Eichelbaum, M, (eds), Philadelphia, PA: Lippincott-Raven Press
    • DeVane, CL, Markowitz, JS (2000) Drugs as substrates of metabolic enzymes: antipsychotics. In: Levy, RH, Thummel, KE, Trager, WF, Hansten, PD, Eichelbaum, M, (eds). Metabolic Drug Interactions. Philadelphia, PA: Lippincott-Raven Press, pp. 245-258.
    • (2000) Metabolic Drug Interactions , pp. 245-258
    • Devane, C.L.1    Markowitz, J.S.2
  • 11
    • 0033063442 scopus 로고    scopus 로고
    • Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4
    • Fang, J., Borurin, M., Baker, GB (1999) Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4. Naunyn Schmiedebergs Arch Pharmacol 359: 147-151.
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.359 , pp. 147-151
    • Fang, J.1    Borurin, M.2    Baker, G.B.3
  • 12
    • 0030698640 scopus 로고    scopus 로고
    • Determinants of medication compliance in schizophrenia: Empirical and clinical findings
    • Fenton, WS, Blyler, CR, Heinssen, RK (1997) Determinants of medication compliance in schizophrenia: empirical and clinical findings. Schizophr Bull 23: 637-651.
    • (1997) Schizophr Bull , vol.23 , pp. 637-651
    • Fenton, W.S.1    Blyler, C.R.2    Heinssen, R.K.3
  • 13
    • 0025055503 scopus 로고
    • On the importance of being (stereo) specific
    • Fishman, WH (1989) On the importance of being (stereo) specific. Clin Chim Acta 186: 129-132.
    • (1989) Clin Chim Acta , vol.186 , pp. 129-132
    • Fishman, W.H.1
  • 14
    • 0026725830 scopus 로고
    • Molecular cloning and chromosomal localization of a human gene encoding D-amino acid oxidase
    • Fukui, K., Miyake, Y. (1992) Molecular cloning and chromosomal localization of a human gene encoding D-amino acid oxidase. J Biol Chem 267: 18631-18638.
    • (1992) J Biol Chem , vol.267 , pp. 18631-18638
    • Fukui, K.1    Miyake, Y.2
  • 15
    • 0023710146 scopus 로고
    • In vivo and in vitro expression of porcine D-amino acid oxidase: In vitro system for the synthesis of a functional enzyme
    • Fukui, K., Momoi, K., Watanabe, F., Miyake, Y. (1988) In vivo and in vitro expression of porcine D-amino acid oxidase: In vitro system for the synthesis of a functional enzyme. Biochemistry 27: 6693-6697.
    • (1988) Biochemistry , vol.27 , pp. 6693-6697
    • Fukui, K.1    Momoi, K.2    Watanabe, F.3    Miyake, Y.4
  • 16
    • 0023657734 scopus 로고
    • Molecular cloning and sequence analysis of cDNAs encoding porcine kidney D-amino acid oxidase
    • Fukui, K., Watanabe, F., Shibata, T., Miyake, Y. (1987) Molecular cloning and sequence analysis of cDNAs encoding porcine kidney D-amino acid oxidase. Biochemistry 26: 3612-3618.
    • (1987) Biochemistry , vol.26 , pp. 3612-3618
    • Fukui, K.1    Watanabe, F.2    Shibata, T.3    Miyake, Y.4
  • 17
    • 0016278916 scopus 로고
    • The nature of D-serine induced nephrotoxicity
    • Ganote, CE, Peterson, DR, Carone, FA (1974) The nature of D-serine induced nephrotoxicity. Am J Pathol 77: 269-282.
    • (1974) Am J Pathol , vol.77 , pp. 269-282
    • Ganote, C.E.1    Peterson, D.R.2    Carone, F.A.3
  • 18
    • 0016769615 scopus 로고
    • D-valine as a selective agent for normal human and rodent epithelial cells in culture
    • Gilbert, SF, Migeon, BR (1975) D-valine as a selective agent for normal human and rodent epithelial cells in culture. Cell 5: 11-17.
    • (1975) Cell , vol.5 , pp. 11-17
    • Gilbert, S.F.1    Migeon, B.R.2
  • 19
    • 0032902238 scopus 로고    scopus 로고
    • A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia
    • Goff, DC, Tsai, G., Levitt, J., Hayden, DL, McCarley, R., Coyle, JT (1999) A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. Arch Gen Psychiat 56: 21-27.
    • (1999) Arch Gen Psychiat , vol.56 , pp. 21-27
    • Goff, D.C.1    Tsai, G.2    Levitt, J.3    Hayden, D.L.4    McCarley, R.5    Coyle, J.T.6
  • 20
    • 0024212654 scopus 로고
    • Epithelial cells in tissue culture
    • Gstraunthaler, GJ (1988) Epithelial cells in tissue culture. Renal Physiol Biochem 11: 1-42.
    • (1988) Renal Physiol Biochem , vol.11 , pp. 1-42
    • Gstraunthaler, G.J.1
  • 21
    • 0021848486 scopus 로고
    • Biochemical characterization of renal epithelial cell cultures (LLC-PK1 and MDCK)
    • Gstraunthaler, G., Pfaller, W., Kotanko, P. (1985) Biochemical characterization of renal epithelial cell cultures (LLC-PK1 and MDCK). Am J Physiol 248 (4 pt 2). F536 - F544.
    • (1985) Am J Physiol , vol.248 , Issue.4
    • Gstraunthaler, G.1    Pfaller, W.2    Kotanko, P.3
  • 22
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of D-serine in patients with schizophrenia: Evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
    • Hashimoto, K., Fukushimo, T., Shinizu, E., Komatsu, N., Watanabe, H., Shinoda, N., et al. (2003) Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry 60: 572-576.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 572-576
    • Hashimoto, K.1    Fukushimo, T.2    Shinizu, E.3    Komatsu, N.4    Watanabe, H.5    Shinoda, N.6
  • 24
    • 0027473657 scopus 로고
    • Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging
    • Hashimoto, A., Nishikawa, T., Oka, T., Takahashi, K. (1993) Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging. J Neurochem 60: 783-786.
    • (1993) J Neurochem , vol.60 , pp. 783-786
    • Hashimoto, A.1    Nishikawa, T.2    Oka, T.3    Takahashi, K.4
  • 25
    • 0029025347 scopus 로고
    • Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis
    • Hashimoto, A., Oka, T., Nishikawa, T. (1995) Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis. Neuroscience 66: 635-643.
    • (1995) Neuroscience , vol.66 , pp. 635-643
    • Hashimoto, A.1    Oka, T.2    Nishikawa, T.3
  • 26
    • 0030850891 scopus 로고    scopus 로고
    • Free D-aspartate and D-serine in the mammalian brain and periphery
    • Hashimoto, A., Oka, T. (1997) Free D-aspartate and D-serine in the mammalian brain and periphery. Prog Neurobiol 52: 325-353.
    • (1997) Prog Neurobiol , vol.52 , pp. 325-353
    • Hashimoto, A.1    Oka, T.2
  • 27
    • 1442333154 scopus 로고    scopus 로고
    • High dose glycine added to olanzapine and risperidone for the treatment of schizophrenia
    • Heresco-Levy, U., Ermilov, M., Lichtenberg, P., Bar, G., Javitt, DC (2004) High dose glycine added to olanzapine and risperidone for the treatment of schizophrenia. Biol Psychiatry 55: 165-171.
    • (2004) Biol Psychiatry , vol.55 , pp. 165-171
    • Heresco-Levy, U.1    Ermilov, M.2    Lichtenberg, P.3    Bar, G.4    Javitt, D.C.5
  • 29
    • 15444377601 scopus 로고    scopus 로고
    • D-Serine Efficacy as Add-on Pharmacotherapy to Risperidone and Olanzapine for Treatment-Refractory Schizophrenia
    • Heresco-Levy, U., Javitt, DC, Ebstein, R., Vass, A., Lichtenberg, P., Bar, G., et al. (2005) D-Serine Efficacy as Add-on Pharmacotherapy to Risperidone and Olanzapine for Treatment-Refractory Schizophrenia. Biol Psychiatry 57: 577-585.
    • (2005) Biol Psychiatry , vol.57 , pp. 577-585
    • Heresco-Levy, U.1    Javitt, D.C.2    Ebstein, R.3    Vass, A.4    Lichtenberg, P.5    Bar, G.6
  • 31
    • 0014048257 scopus 로고
    • Isolation and identification of urinary chlorpromazine metabolites in man
    • Huang, CL (1967) Isolation and identification of urinary chlorpromazine metabolites in man. Int J Neuropharmacol 6: 1-13.
    • (1967) Int J Neuropharmacol , vol.6 , pp. 1-13
    • Huang, C.L.1
  • 33
    • 56449117143 scopus 로고    scopus 로고
    • Chlorpromazine oligomer is a potentially active substance that inhibits human D-amino acid oxidase, product of a susceptibility gene for schizophrenia
    • Iwana, S., Kawazoe, T., Park, HK, Tsuchiya, K., Ono, K., Yorita, K., et al. (2008) Chlorpromazine oligomer is a potentially active substance that inhibits human D-amino acid oxidase, product of a susceptibility gene for schizophrenia. J Enzyme Inhib Med Chem 23: 901-911.
    • (2008) J Enzyme Inhib Med Chem , vol.23 , pp. 901-911
    • Iwana, S.1    Kawazoe, T.2    Park, H.K.3    Tsuchiya, K.4    Ono, K.5    Yorita, K.6
  • 34
    • 33751519528 scopus 로고    scopus 로고
    • Crystal structure of human D-amino acid oxidase: Context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring
    • Kawazoe, T., Tsuge, H., Pilone, MS, Fukui, K. (2006) Crystal structure of human D-amino acid oxidase: Context-dependent variability of the backbone conformation of the VAAGL hydrophobic stretch located at the si-face of the flavin ring. Protein Sci 15: 2708-2717.
    • (2006) Protein Sci , vol.15 , pp. 2708-2717
    • Kawazoe, T.1    Tsuge, H.2    Pilone, M.S.3    Fukui, K.4
  • 35
    • 0028342655 scopus 로고
    • Risperidone in the treatment of schizophrenia
    • Marder, SR, Meibach, RC (1994) Risperidone in the treatment of schizophrenia. Am J Psychiatry 151: 825-835.
    • (1994) Am J Psychiatry , vol.151 , pp. 825-835
    • Marder, S.R.1    Meibach, R.C.2
  • 36
    • 0014027814 scopus 로고
    • A new method of preparation of D-amino acid oxidase apoprotein and a conformational change after its combination with flavin adenine dinucleotide
    • Massey, V., Curti, B. (1966) A new method of preparation of D-amino acid oxidase apoprotein and a conformational change after its combination with flavin adenine dinucleotide. J Biol Chem 241: 3417-3423.
    • (1966) J Biol Chem , vol.241 , pp. 3417-3423
    • Massey, V.1    Curti, B.2
  • 37
    • 0019859249 scopus 로고
    • Transepithelial transport in cell culture: D-glucose transport by a pig kidney cell line (LLCPKI)
    • Misfeldt, DS, Sanders, MJ (1981) Transepithelial transport in cell culture: D-glucose transport by a pig kidney cell line (LLCPKI). J Membr Biol 59: 13-18.
    • (1981) J Membr Biol , vol.59 , pp. 13-18
    • Misfeldt, D.S.1    Sanders, M.J.2
  • 38
    • 0342879925 scopus 로고    scopus 로고
    • Atypical neuroleptics: A new approach in the treatment of negative symptoms
    • Möller, HJ (1999) Atypical neuroleptics: a new approach in the treatment of negative symptoms. Eur Arch Psychiatry Clin Neurosci 249 (Suppl 4). 99-107.
    • (1999) Eur Arch Psychiatry Clin Neurosci , vol.249 , Issue.4 , pp. 99-107
    • Möller, H.J.1
  • 39
    • 0041832180 scopus 로고    scopus 로고
    • Management of the negative symptoms of schizophrenia: New treatment options
    • Möller, HJ (2003) Management of the negative symptoms of schizophrenia: new treatment options. CNS Drugs 17: 793-823.
    • (2003) CNS Drugs , vol.17 , pp. 793-823
    • Möller, H.J.1
  • 40
    • 0023681465 scopus 로고
    • Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase
    • Momoi, K., Fukui, K., Watanabe, F., Miyake, Y. (1988) Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase. FEBS Lett 238: 180-184.
    • (1988) FEBS Lett , vol.238 , pp. 180-184
    • Momoi, K.1    Fukui, K.2    Watanabe, F.3    Miyake, Y.4
  • 42
    • 0035728196 scopus 로고    scopus 로고
    • Iatrogenic disorders associated with conventional vs. atypical antipsychotics
    • Nasrallah, HA, Mulvihill, T. (2001) Iatrogenic disorders associated with conventional vs. atypical antipsychotics. Ann Clin Psychiatry 13: 215-227.
    • (2001) Ann Clin Psychiatry , vol.13 , pp. 215-227
    • Nasrallah, H.A.1    Mulvihill, T.2
  • 43
    • 0017580981 scopus 로고
    • Effect of alcohols on the structure and function of D amino acid oxidase
    • DOI 10.1021/bi00620a021
    • Ohama, H., Sugiura, N., Tanaka, F., Yagi, K. (1977) Effect of alcohols on the structure and function of D-amino-acid oxidase. Biochemistry 16: 126-131. (Pubitemid 8030076)
    • (1977) Biochemistry , vol.16 , Issue.1 , pp. 126-131
    • Ohama, H.1    Sugiura, N.2    Tanaka, F.3    Yagi, K.4
  • 44
    • 33645321857 scopus 로고    scopus 로고
    • Potential role for astroglial D-amino acid oxidase in extracellular D-serine metabolism and cytotoxicity
    • Park, HK, Shishido, Y., Ichise-Shishido, S., Kawazoe, T., Ono, K., Iwana, S., et al. (2006) Potential role for astroglial D-amino acid oxidase in extracellular D-serine metabolism and cytotoxicity. J Biochem 139: 295-304.
    • (2006) J Biochem , vol.139 , pp. 295-304
    • Park, H.K.1    Shishido, Y.2    Ichise-Shishido, S.3    Kawazoe, T.4    Ono, K.5    Iwana, S.6
  • 46
    • 0025164958 scopus 로고
    • Morphology of the Differentiation and Maturation of LLC-PK1Epithelia
    • Pfaller, W., Gstraunthaler, G., Loidl, P. (1990) Morphology of the Differentiation and Maturation of LLC-PK1Epithelia. J Cell Physiol 142: 247-254.
    • (1990) J Cell Physiol , vol.142 , pp. 247-254
    • Pfaller, W.1    Gstraunthaler, G.2    Loidl, P.3
  • 47
    • 0033679728 scopus 로고    scopus 로고
    • D-Amino acid oxidase: New findings
    • Pilone, MS (2000) D-Amino acid oxidase: new findings. Cell Mol Life Sci 57: 1732-1747.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1732-1747
    • Pilone, M.S.1
  • 48
    • 0037679084 scopus 로고    scopus 로고
    • Interactions between the cytochrome P450 system and the second-generation antipsychotics
    • Prior, TI, Baker, GB (2003) Interactions between the cytochrome P450 system and the second-generation antipsychotics. J Psychiatry Neurosci 28: 99-112.
    • (2003) J Psychiatry Neurosci , vol.28 , pp. 99-112
    • Prior, T.I.1    Baker, G.B.2
  • 49
    • 0019801768 scopus 로고
    • Localization of the Na+-sugar cotransport system in a kidney epithelial cell line (LLC-PKI)
    • Rabito, CA (1981) Localization of the Na+-sugar cotransport system in a kidney epithelial cell line (LLC-PKI). Biochim Biophys Acta 649: 286-296.
    • (1981) Biochim Biophys Acta , vol.649 , pp. 286-296
    • Rabito, C.A.1
  • 50
    • 0021072131 scopus 로고
    • Phosphate uptake by a kidney cell line (LLC-PK1)
    • Rabito, CA (1983) Phosphate uptake by a kidney cell line (LLC-PK1). Am J Physiol 245: F22 - F31.
    • (1983) Am J Physiol , vol.245
    • Rabito, C.A.1
  • 51
    • 0019153492 scopus 로고
    • Na+-dependent sugar transport in a cultured epithelial cell line from pig kidney
    • Rabito, CA, Ausiello, DA (1980) Na+-dependent sugar transport in a cultured epithelial cell line from pig kidney. J Membr Biol 54: 31-38.
    • (1980) J Membr Biol , vol.54 , pp. 31-38
    • Rabito, C.A.1    Ausiello, D.A.2
  • 52
    • 0020490734 scopus 로고
    • Polarized amino acid transport by an epithelial cell of renal origin (LLC-PK1): The basolateral systems
    • Rabito, CA, Karish, MV (1982) Polarized amino acid transport by an epithelial cell of renal origin (LLC-PK1). the basolateral systems. J Biol Chem 257: 6802-6808.
    • (1982) J Biol Chem , vol.257 , pp. 6802-6808
    • Rabito, C.A.1    Karish, M.V.2
  • 53
    • 0020527543 scopus 로고
    • Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1): The apical systems
    • Rabito, CA, Karish, MV (1983) Polarized amino acid transport by an epithelial cell line of renal origin (LLC-PK1). the apical systems. J Biol Chem 258: 2543-2547.
    • (1983) J Biol Chem , vol.258 , pp. 2543-2547
    • Rabito, C.A.1    Karish, M.V.2
  • 54
    • 0021341204 scopus 로고
    • Alkaline phosphatase and -3-glutamyltranspeptidase as polarization markers during the organization of LLC- PK1 cells into an epithelial membrane
    • Rabito, CA, Kreisberg, JI, Wight, D. (1984) Alkaline phosphatase and -3-glutamyltranspeptidase as polarization markers during the organization of LLC- PK1 cells into an epithelial membrane. J Biol Chem 259: 574-582.
    • (1984) J Biol Chem , vol.259 , pp. 574-582
    • Rabito, C.A.1    Kreisberg, J.I.2    Wight, D.3
  • 55
    • 0032532332 scopus 로고    scopus 로고
    • Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin
    • Salzer, JL, Lovejoy, L., Liner, MC, Rosen, C. (1998) Ran-2, a glial lineage marker, is a GPI-anchored form of ceruloplasmin. J Neurosci Res 54: 147-157.
    • (1998) J Neurosci Res , vol.54 , pp. 147-157
    • Salzer, J.L.1    Lovejoy, L.2    Liner, M.C.3    Rosen, C.4
  • 56
    • 0028988978 scopus 로고
    • D-Serine an endogenous synaptic modulator: Localization to astrocytes and glutamatestimulated release
    • Schell, MJ, Molliver, ME, Snyder, SH (1995) D-Serine an endogenous synaptic modulator: localization to astrocytes and glutamatestimulated release. Proc Natl Acad Sci U S A 92: 3948-3952.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3948-3952
    • Schell, M.J.1    Molliver, M.E.2    Snyder, S.H.3
  • 57
    • 0029930927 scopus 로고    scopus 로고
    • Risperidone compared with new and reference antipsychotic drugs: In vitro and in vivo receptor binding
    • Berlin
    • Schotte, A., Janssen, PF, Gommeren, W., Luyten, WH, Van Gompel, P., Lesage, AS, et al. (1996) Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berlin) 124: 57-73.
    • (1996) Psychopharmacology , vol.124 , pp. 57-73
    • Schotte, A.1    Janssen, P.F.2    Gommeren, W.3    Luyten, W.H.4    Van Gompel, P.5    Lesage, A.S.6
  • 58
    • 0027743268 scopus 로고
    • Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography
    • Schotte, A., Janssen, PF, Megens, AA, Leysen, JE (1993) Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography. Brain Res 631: 191-202.
    • (1993) Brain Res , vol.631 , pp. 191-202
    • Schotte, A.1    Janssen, P.F.2    Megens, A.A.3    Leysen, J.E.4
  • 59
    • 0033987060 scopus 로고    scopus 로고
    • Cytochcorome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone
    • Berl
    • Scordo, MG, Spina, E., Facciola, G., Avenoso, A., Johannsson, I., Dahl, ML (1999) Cytochcorome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone. Psychopharmacology (Berl) 147: 300-305.
    • (1999) Psychopharmacology , vol.147 , pp. 300-305
    • Scordo, M.G.1    Spina, E.2    Facciol, G.3    Avenoso, A.4    Johannsson, I.5    Dahl, M.L.6
  • 60
    • 26444441486 scopus 로고    scopus 로고
    • An update of fast-off dopamine D2 atypical antipsychotics
    • Seeman, P. (2005) An update of fast-off dopamine D2 atypical antipsychotics. Am J Psychiatry 162: 1984-1985.
    • (2005) Am J Psychiatry , vol.162 , pp. 1984-1985
    • Seeman, P.1
  • 62
    • 0020465869 scopus 로고
    • The development of gamma- glutamyltransferase in a pig renal-epithelial-cell line in vitro relationship to amino acid transport
    • Sepúlveda, FV, Burton, KA, Pearson, JD (1982) The development of gamma- glutamyltransferase in a pig renal-epithelial-cell line in vitro relationship to amino acid transport. Biochem J 208: 509-512.
    • (1982) Biochem J , vol.208 , pp. 509-512
    • Sepúlveda, F.V.1    Burton, K.A.2    Pearson, J.D.3
  • 63
    • 0019957889 scopus 로고
    • Characterization of neutral amino acid uptake by cultured epithelial cells from pig kidney
    • Sepúlveda, FV, Pearson, JD (1982) Characterization of neutral amino acid uptake by cultured epithelial cells from pig kidney. J Cell Physiol 112: 182-188.
    • (1982) J Cell Physiol , vol.112 , pp. 182-188
    • Sepúlveda, F.V.1    Pearson, J.D.2
  • 64
    • 0036841941 scopus 로고    scopus 로고
    • Forty years of neurotransmitters: A personal account
    • Snyder, SH (2002) Forty years of neurotransmitters: A personal account. Arch Gen Psychiatry 59: 983-994.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 983-994
    • Snyder, S.H.1
  • 65
    • 0028301264 scopus 로고
    • Stereoselective antagonism by enantiomers of alanine and serine of phencyclidine-induced hyperactivity, stereotypy and ataxia in the rat
    • Tanii, Y., Nishikawa, T., Hashimoto, A., Takahashi, K. (1994) Stereoselective antagonism by enantiomers of alanine and serine of phencyclidine-induced hyperactivity, stereotypy and ataxia in the rat. J Pharmacol Exp Ther 269: 1040-1048.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1040-1048
    • Tanii, Y.1    Nishikawa, T.2    Hashimoto, A.3    Takahashi, K.4
  • 66
    • 4444220443 scopus 로고    scopus 로고
    • Identification and characterization of major degradation products of risperidone in bulk drug and pharmaceutical dosage forms
    • Tomar, RS, Joseph, TJ, Murthy, AS, Yadav, DV, Subbaiah, G., Krishna Reddy, KV (2004) Identification and characterization of major degradation products of risperidone in bulk drug and pharmaceutical dosage forms. J Pharm Biomed Anal 36: 231-235.
    • (2004) J Pharm Biomed Anal , vol.36 , pp. 231-235
    • Tomar, R.S.1    Joseph, T.J.2    Murthy, A.S.3    Yadav, D.V.4    Subbaiah, G.5    Krishna Reddy, K.V.6
  • 67
    • 0032403626 scopus 로고    scopus 로고
    • D-serine added to antipsychotics for the treatment of schizophrenia
    • Tsai, G., Yang, P., Chung, L-C., Lange, N., Coyle, JT (1998) D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry 44: 1081-1089.
    • (1998) Biol Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.-C.3    Lange, N.4    Coyle, J.T.5
  • 69
    • 0037123710 scopus 로고    scopus 로고
    • Gene expression of D-amino acid oxidase in cultured rat astrocytcs: Regional and cell type specific expression
    • Urai, Y., Jinnouchi, O., Kwak, KT, Suzue, A., Nagahiro, S., Fukui, K. (2002) Gene expression of D-amino acid oxidase in cultured rat astrocytcs: Regional and cell type specific expression. Neurosci Lett 324: 101-104.
    • (2002) Neurosci Lett , vol.324 , pp. 101-104
    • Urai, Y.1    Jinnouchi, O.2    Kwak, K.T.3    Suzue, A.4    Nagahiro, S.5    Fukui, K.6
  • 71
    • 0342891014 scopus 로고
    • Inhibitory action of chlorpromazine on the oxidation of D-amino-acid in the diencephalon part of the brain
    • Yagi, K., Nagatsu, T., Ozawa, T. (1956) Inhibitory action of chlorpromazine on the oxidation of D-amino-acid in the diencephalon part of the brain. Nature 177: 891-892.
    • (1956) Nature , vol.177 , pp. 891-892
    • Yagi, K.1    Nagatsu, T.2    Ozawa, T.3
  • 72
    • 50549179786 scopus 로고
    • Mechanism of inhibition of D-amino acid oxidase. IV. Inhibitory action of chlorpromazine
    • Yagi, K., Ozawa, T., Nagatsu, T. (1960) Mechanism of inhibition of D-amino acid oxidase. IV. Inhibitory action of chlorpromazine. Biochim Biophys Acta 43: 310-317.
    • (1960) Biochim Biophys Acta , vol.43 , pp. 310-317
    • Yagi, K.1    Ozawa, T.2    Nagatsu, T.3
  • 73
    • 0017877045 scopus 로고
    • Chlorpromazine levels in plasma and milk of nursing mothers
    • Wiles, DH, Orr, MW, Kolakowska, T. (1978) Chlorpromazine levels in plasma and milk of nursing mothers. Br J Clin Pharmacol 5: 272-273.
    • (1978) Br J Clin Pharmacol , vol.5 , pp. 272-273
    • Wiles, D.H.1    Orr, M.W.2    Kolakowska, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.