Potential cytotoxic effect of hydroxypyruvate produced from d-serine by astroglial d-amino acid oxidase

Journal of Biochemistry

Volumn 148, Issue 6, 2010, Pages 743-753

  Chung, Seong Pil ^a   Sogabe, Kimiko ^a   Park, Hwan Ki ^a,c   Song, Ying ^a   Ono, Koji ^a   Abou El Magd, Rabab M ^a   Shishido, Yuji ^a   Yorita, Kazuko ^a   Sakai, Takashi ^a   Fukui, Kiyoshi ^a,b  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c Mayo Clinic   (United States)

Author keywords

hydroxypyruvate; cytotoxicity; d Amino acid oxidase; d serine; oxidative stress

Indexed keywords

BETA HYDROXYPYRUVATE; CATALASE; DEXTRO AMINO ACID; DEXTRO AMINO ACID OXIDASE; DEXTRO SERINE; NORPHENAZONE; PYRUVIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; MACROGLIA; NERVE CELL; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT;

ANIMALS; APOPTOSIS; ASTROCYTES; BIOCATALYSIS; BRAIN; CELL SURVIVAL; CELLS, CULTURED; D-AMINO-ACID OXIDASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ASSAYS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MICE; PYRUVATES; RATS; SERINE; SWINE; TRANSFECTION;

MAMMALIA;

EID: 78649918890     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq112     Document Type: Article

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