-
1
-
-
79955955380
-
Intrahepatic natural killer T cell populations are increased in human hepatic steatosis
-
Adler, M., Taylor, S., Okebugwu, K., Yee, H., Fielding, C., Fielding, G., and Poles, M. (2011). Intrahepatic natural killer T cell populations are increased in human hepatic steatosis. World J. Gastroenterol. 17, 1725-1731
-
(2011)
World J. Gastroenterol.
, vol.17
, pp. 1725-1731
-
-
Adler, M.1
Taylor, S.2
Okebugwu, K.3
Yee, H.4
Fielding, C.5
Fielding, G.6
Poles, M.7
-
2
-
-
53049101877
-
Randomized, placebo-controlled trial of pioglita-zone in nondiabetic subjects with nonalcoholic steatohepatitis
-
Aithal, G. P., Thomas, J. A., Kaye, P. V., Lawson, A., Ryder, S. D., Spendlove, I., Austin, A. S., Freeman, J. G., Morgan, L., and Webber, J. (2008). Randomized, placebo-controlled trial of pioglita-zone in nondiabetic subjects with nonalcoholic steatohepatitis. Gas-troenterology 135, 1176-1184.
-
(2008)
Gas-troenterology
, vol.135
, pp. 1176-1184
-
-
Aithal, G.P.1
Thomas, J.A.2
Kaye, P.V.3
Lawson, A.4
Ryder, S.D.5
Spendlove, I.6
Austin, A.S.7
Freeman, J.G.8
Morgan, L.9
Webber, J.10
-
3
-
-
70349678823
-
Adiponectin knockout mice on high fat diet develop fibrosing steatohepati-tis
-
Asano, T., Watanabe, K., Kubota, N., Gunji, T., Omata, M., Kadowaki, T., and Ohnishi, S. (2009). Adiponectin knockout mice on high fat diet develop fibrosing steatohepati-tis. J. Gastroenterol. Hepatol. 24, 1669-1676.
-
(2009)
J. Gastroenterol. Hepatol.
, vol.24
, pp. 1669-1676
-
-
Asano, T.1
Watanabe, K.2
Kubota, N.3
Gunji, T.4
Omata, M.5
Kadowaki, T.6
Ohnishi, S.7
-
4
-
-
24144432258
-
Liver fibrogenesis:anew role for the renin-angiotensin system
-
Bataller, R., Sancho-Bru, P., Gines, P., and Brenner, D. A. (2005). Liver fibrogenesis:anew role for the renin-angiotensin system. Antioxid. Redox Signal. 7, 1346-1355.
-
(2005)
Antioxid. Redox Signal.
, vol.7
, pp. 1346-1355
-
-
Bataller, R.1
Sancho-Bru, P.2
Gines, P.3
Brenner, D.A.4
-
5
-
-
79952301247
-
Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease
-
Beaven, S. W., Wroblewski, K., Wang, J., Hong, C., Bensinger, S., Tsukamoto, H., and Tontonoz, P. (2011). Liver X receptor signaling is a determinant of stellate cell activation and susceptibility to fibrotic liver disease. Gastroenterology 140, 1052-1062.
-
(2011)
Gastroenterology
, vol.140
, pp. 1052-1062
-
-
Beaven, S.W.1
Wroblewski, K.2
Wang, J.3
Hong, C.4
Bensinger, S.5
Tsukamoto, H.6
Tontonoz, P.7
-
6
-
-
33751545838
-
A placebo-controlled trial of pioglita-zone in subjects with nonalcoholic steatohepatitis
-
Belfort, R., Harrison, S. A., Brown, K., Darland, C., Finch, J., Hardies, J., Balas, B., Gastaldelli, A., Tio, F., Pulcini, J., Berria, R., Ma, J. Z., Dwivedi, S., Havranek, R., Fincke, C., DeFronzo, R., Bannayan, G. A., Schenker, S., and Cusi, K. (2006). A placebo-controlled trial of pioglita-zone in subjects with nonalcoholic steatohepatitis. N. Engl. J. Med. 355, 2297-2307.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
Darland, C.4
Finch, J.5
Hardies, J.6
Balas, B.7
Gastaldelli, A.8
Tio, F.9
Pulcini, J.10
Berria, R.11
Ma, J.Z.12
Dwivedi, S.13
Havranek, R.14
Fincke, C.15
DeFronzo, R.16
Bannayan, G.A.17
Schenker, S.18
Cusi, K.19
-
7
-
-
42449144221
-
The obesity epidemic: pharmacological challenges
-
Bloom, S. R., Kuhajda, F. P., Laher, I., Pi-Sunyer, X., Ronnett, G. V., Tan, T. M., and Weigle, D. S. (2008). The obesity epidemic: pharmacological challenges. Mol. Interv. 8, 82-98.
-
(2008)
Mol. Interv.
, vol.8
, pp. 82-98
-
-
Bloom, S.R.1
Kuhajda, F.P.2
Laher, I.3
Pi-Sunyer, X.4
Ronnett, G.V.5
Tan, T.M.6
Weigle, D.S.7
-
8
-
-
24044432235
-
Exposure to bacterial cell wall products triggers an inflammatory phe-notype in hepatic stellate cells
-
Brun, P., Castagliuolo, I., Pinzani, M., Palu, G., and Martines, D. (2005). Exposure to bacterial cell wall products triggers an inflammatory phe-notype in hepatic stellate cells. Am. J. Physiol. Gastrointest. Liver Physiol. 289, G571-G578.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.289
-
-
Brun, P.1
Castagliuolo, I.2
Pinzani, M.3
Palu, G.4
Martines, D.5
-
9
-
-
1942454793
-
Nonalcoholic steatohepatitis
-
Brunt, E. M. (2004). Nonalcoholic steatohepatitis. Semin. Liver Dis. 24, 3-20.
-
(2004)
Semin. Liver Dis.
, vol.24
, pp. 3-20
-
-
Brunt, E.M.1
-
10
-
-
1442281989
-
Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver
-
Bugianesi, E., Manzini, P., D'Antico, S., Vanni, E., Longo, F., Leone, N., Mas-sarenti, P., and Rizzetto, M. (2004). Relative contribution of iron burden, HFE mutations, and insulin resistance to fibrosis in nonalcoholic fatty liver. Hepatology 39, 179-187.
-
(2004)
Hepatology
, vol.39
, pp. 179-187
-
-
Bugianesi, E.1
Manzini, P.2
D'Antico, S.3
Vanni, E.4
Longo, F.5
Leone, N.6
Mas-sarenti, P.7
Rizzetto, M.8
-
11
-
-
34548162930
-
Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells
-
Cao, Q., Mak, K. M., and Lieber, C. S. (2007). Leptin represses matrix metalloproteinase-1 gene expression in LX2 human hepatic stellate cells. J. Hepatol. 46, 124-133.
-
(2007)
J. Hepatol.
, vol.46
, pp. 124-133
-
-
Cao, Q.1
Mak, K.M.2
Lieber, C.S.3
-
12
-
-
4444382031
-
Systemic levels of lipid peroxidation and its metabolic and dietary correlates in patients with nonalcoholic steatohepatitis
-
Chalasani, N., Deeg, M. A., and Crabb, D. W. (2004). Systemic levels of lipid peroxidation and its metabolic and dietary correlates in patients with nonalcoholic steatohepatitis. Am. J. Gastroenterol. 99, 1497-1502.
-
(2004)
Am. J. Gastroenterol.
, vol.99
, pp. 1497-1502
-
-
Chalasani, N.1
Deeg, M.A.2
Crabb, D.W.3
-
13
-
-
18244364864
-
NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome
-
Chitturi, S., Abeygunasekera, S., Far-rell, G. C., Holmes-Walker, J., Hui, J. M., Fung, C., Karim, R., Lin, R., Samarasinghe, D., Liddle, C., Welt-man, M., and George, J. (2002). NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 35, 373-379.
-
(2002)
Hepatology
, vol.35
, pp. 373-379
-
-
Chitturi, S.1
Abeygunasekera, S.2
Far-rell, G.C.3
Holmes-Walker, J.4
Hui, J.M.5
Fung, C.6
Karim, R.7
Lin, R.8
Samarasinghe, D.9
Liddle, C.10
Welt-man, M.11
George, J.12
-
14
-
-
78449240951
-
Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway
-
Choi, S. S., Syn, W. K., Karaca, G. F., Omenetti, A., Moylan, C. A., Witek, R. P., Agboola,K. M., Jung, Y., Mich-elotti, G. A., and Diehl,A. M. (2010). Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. J. Biol. Chem. 285, 36551-36560.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 36551-36560
-
-
Choi, S.S.1
Syn, W.K.2
Karaca, G.F.3
Omenetti, A.4
Moylan, C.A.5
Witek, R.P.6
Agboola, K.M.7
Jung, Y.8
Mich-elotti, G.A.9
Diehl, A.M.10
-
15
-
-
79959517565
-
Human fatty liver disease: old questions and new insights
-
Cohen, J. C., Horton, J. D., and Hobbs, H. H. (2011). Human fatty liver disease: old questions and new insights. Science 332, 1519-1523.
-
(2011)
Science
, vol.332
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.H.3
-
16
-
-
0029846756
-
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice
-
Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., and Taub, R. (1996). Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science 274, 1379-1383.
-
(1996)
Science
, vol.274
, pp. 1379-1383
-
-
Cressman, D.E.1
Greenbaum, L.E.2
DeAngelis, R.A.3
Ciliberto, G.4
Furth, E.E.5
Poli, V.6
Taub, R.7
-
17
-
-
0031947715
-
Steatohepatitis: a tale of two 'hits'?
-
Day, C. P., and James, O. F. (1998). Steatohepatitis: a tale of two "hits?" Gastroenterology 114, 842-845.
-
(1998)
Gastroenterology
, vol.114
, pp. 842-845
-
-
Day, C.P.1
James, O.F.2
-
18
-
-
33745739887
-
NADPH oxi-dase in the liver: defensive, offensive, or fibrogenic?
-
De Minicis, S., Bataller, R., and Brenner, D. A. (2006). NADPH oxi-dase in the liver: defensive, offensive, or fibrogenic? Gastroenterology 131, 272-275.
-
(2006)
Gastroenterology
, vol.131
, pp. 272-275
-
-
De Minicis, S.1
Bataller, R.2
Brenner, D.A.3
-
19
-
-
77957946240
-
Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibro-sis
-
De Minicis, S.,Seki, E., Paik,Y. H., Oster-reicher, C. H., Kodama, Y., Kluwe, J., Torozzi, L., Miyai, K., Benedetti, A., Schwabe, R. F., and Brenner, D. A. (2010). Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibro-sis. Hepatology 52, 1420-1430.
-
(2010)
Hepatology
, vol.52
, pp. 1420-1430
-
-
De Minicis, S.1
Seki, E.2
Paik, Y.H.3
Oster-reicher, C.H.4
Kodama, Y.5
Kluwe, J.6
Torozzi, L.7
Miyai, K.8
Benedetti, A.9
Schwabe, R.F.10
Brenner, D.A.11
-
21
-
-
38049131878
-
Combination of N-acetylcysteine and met-formin improves histological steato-sis and fibrosis in patients with non-alcoholic steatohepatitis
-
de Oliveira, C. P., Stefano, J. T., de Siqueira, E. R., Silva, L. S., de Campos Mazo,D. F., Lima,V. M., Furuya, C. K., Mello, E. S., Souza, F. G., Rabello, F., Santos, T. E., Nogueira, M. A., Caldwell, S. H., Alves, V. A., and Carrilho, F. J. (2008). Combination of N-acetylcysteine and met-formin improves histological steato-sis and fibrosis in patients with non-alcoholic steatohepatitis. Hepa-tol. Res. 38, 159-165.
-
(2008)
Hepa-tol. Res.
, vol.38
, pp. 159-165
-
-
de Oliveira, C.P.1
Stefano, J.T.2
de Siqueira, E.R..3
Silva, L.S.4
de Campos Mazo, D.F.5
Lima, V.M.6
Furuya, C.K.7
Mello, E.S.8
Souza, F.G.9
Rabello, F.10
Santos, T.E.11
Nogueira, M.A.12
Caldwell, S.H.13
Alves, V.A.14
Carrilho, F.J.15
-
22
-
-
25844456719
-
Steato-hepatitis induced by intragastric overfeeding in mice
-
Deng, Q. G., She, H., Cheng, J. H., French, S. W., Koop, D. R., Xiong, S., and Tsukamoto, H. (2005). Steato-hepatitis induced by intragastric overfeeding in mice. Hepatology 42, 905-914.
-
(2005)
Hepatology
, vol.42
, pp. 905-914
-
-
Deng, Q.G.1
She, H.2
Cheng, J.H.3
French, S.W.4
Koop, D.R.5
Xiong, S.6
Tsukamoto, H.7
-
23
-
-
71149117471
-
Immature myeloid cells induced by a high-fat diet contribute to liver inflammation
-
Deng, Z. B., Liu, Y., Liu, C., Xiang, X., Wang, J., Cheng, Z., Shah, S. V., Zhang, S., Zhang, L., Zhuang, X., Michalek, S., Grizzle, W. E., and Zhang, H. G. (2009). Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology 50, 1412-1420.
-
(2009)
Hepatology
, vol.50
, pp. 1412-1420
-
-
Deng, Z.B.1
Liu, Y.2
Liu, C.3
Xiang, X.4
Wang, J.5
Cheng, Z.6
Shah, S.V.7
Zhang, S.8
Zhang, L.9
Zhuang, X.10
Michalek, S.11
Grizzle, W.E.12
Zhang, H.G.13
-
24
-
-
12744259191
-
IL-6-deficient mice are susceptible to ethanol-induced hepatic steato-sis: IL-6 protects against ethanol-induced oxidative stress and mito-chondrial permeability transition in the liver
-
El-Assal, O., Hong, F., Kim, W. H., Radaeva, S., and Gao, B. (2004). IL-6-deficient mice are susceptible to ethanol-induced hepatic steato-sis: IL-6 protects against ethanol-induced oxidative stress and mito-chondrial permeability transition in the liver. Cell. Mol. Immunol. 1, 205-211.
-
(2004)
Cell. Mol. Immunol.
, vol.1
, pp. 205-211
-
-
El-Assal, O.1
Hong, F.2
Kim, W.H.3
Radaeva, S.4
Gao, B.5
-
25
-
-
29744447771
-
Amelioration of nonalcoholic steatohepatitis and glucose intolerance in ob/ob mice by oral immune regulation towards liver-extracted proteins is associated with elevated intrahepatic NKT lymphocytes and serum IL-10 levels
-
Elinav, E., Pappo, O., Sklair-Levy, M., Margalit, M., Shibolet, O., Gomori, M., Alper, R., Thalenfeld, B., Engel-hardt, D., Rabbani, E., and Ilan, Y. (2006). Amelioration of nonalcoholic steatohepatitis and glucose intolerance in ob/ob mice by oral immune regulation towards liver-extracted proteins is associated with elevated intrahepatic NKT lymphocytes and serum IL-10 levels. J. Pathol. 208, 74-81.
-
(2006)
J. Pathol.
, vol.208
, pp. 74-81
-
-
Elinav, E.1
Pappo, O.2
Sklair-Levy, M.3
Margalit, M.4
Shibolet, O.5
Gomori, M.6
Alper, R.7
Thalenfeld, B.8
Engel-hardt, D.9
Rabbani, E.10
Ilan, Y.11
-
26
-
-
33644547706
-
Nonalcoholic fatty liver disease: from steatosis to cirrhosis
-
Farrell, G. C., and Larter, C. Z. (2006). Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatol-ogy 43, S99-S112.
-
(2006)
Hepatol-ogy
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
27
-
-
7644244675
-
The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis
-
Fiorucci, S., Antonelli, E., Rizzo, G., Renga, B., Mencarelli, A., Riccardi, L., Orlandi, S., Pellicciari, R., and Morelli, A. (2004). The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis. Gastroen-terology 127, 1497-1512.
-
(2004)
Gastroen-terology
, vol.127
, pp. 1497-1512
-
-
Fiorucci, S.1
Antonelli, E.2
Rizzo, G.3
Renga, B.4
Mencarelli, A.5
Riccardi, L.6
Orlandi, S.7
Pellicciari, R.8
Morelli, A.9
-
28
-
-
51349083814
-
Risk of severe liver disease in nonalcoholic fatty liver disease with normal amino-transferase levels: a role for insulin resistance and diabetes
-
Fracanzani, A. L., Valenti, L., Bugianesi, E., Andreoletti, M., Colli, A., Vanni, E., Bertelli, C., Marchesini, G., and Fargion, S. (2008). Risk of severe liver disease in nonalcoholic fatty liver disease with normal amino-transferase levels: a role for insulin resistance and diabetes. Hepatology 48, 792-798.
-
(2008)
Hepatology
, vol.48
, pp. 792-798
-
-
Fracanzani, A.L.1
Valenti, L.2
Bugianesi, E.3
Andreoletti, M.4
Colli, A.5
Vanni, E.6
Bertelli, C.7
Marchesini, G.8
Fargion, S.9
-
29
-
-
77955734496
-
Pioglitazone in the treatment of NASH: the role of adiponectin
-
Gastaldelli, A., Harrison, S., Belfort-Aguiar, R., Hardies, J., Balas, B., Schenker, S., and Cusi, K. (2010). Pioglitazone in the treatment of NASH: the role of adiponectin. Aliment. Pharmacol. Ther. 32, 769-775.
-
(2010)
Aliment. Pharmacol. Ther.
, vol.32
, pp. 769-775
-
-
Gastaldelli, A.1
Harrison, S.2
Belfort-Aguiar, R.3
Hardies, J.4
Balas, B.5
Schenker, S.6
Cusi, K.7
-
30
-
-
0242438087
-
Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis
-
George, J., Pera, N., Phung, N., Leclercq, I.,Yun Hou, J., and Farrell,G. (2003). Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis. J. Hepatol. 39, 756-764.
-
(2003)
J. Hepatol.
, vol.39
, pp. 756-764
-
-
George, J.1
Pera, N.2
Phung, N.3
Leclercq, I.4
Yun Hou, J.5
Farrell, G.6
-
31
-
-
33645736419
-
Relationship between oxida-tive stress levels and activation state on a hepatic stellate cell line
-
Guimaraes, E. L., Franceschi, M. F., Grivicich, I., Dal-Pizzol, F., Moreira, J. C., Guaragna, R. M., Borojevic, R., Margis, R., and Guma, F. C. (2006). Relationship between oxida-tive stress levels and activation state on a hepatic stellate cell line. Liver Int. 26, 477-485.
-
(2006)
Liver Int
, vol.26
, pp. 477-485
-
-
Guimaraes, E.L.1
Franceschi, M.F.2
Grivicich, I.3
Dal-Pizzol, F.4
Moreira, J.C.5
Guaragna, R.M.6
Borojevic, R.7
Margis, R.8
Guma, F.C.9
-
32
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas, J. L., Gajiwala, K. S., Maf-fei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Bur-ley, S. K., and Friedman, J. M. (1995). Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269, 543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maf-fei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Bur-ley, S.K.8
Friedman, J.M.9
-
33
-
-
77954521483
-
Autoreac-tive natural killer T cells: promoting immune protection and immune tolerance through varied interactions with myeloid antigen-presenting cells
-
Hegde, S., Fox, L., Wang, X., and Gumperz, J. E. (2010). Autoreac-tive natural killer T cells: promoting immune protection and immune tolerance through varied interactions with myeloid antigen-presenting cells. Immunology 130, 471-483.
-
(2010)
Immunology
, vol.130
, pp. 471-483
-
-
Hegde, S.1
Fox, L.2
Wang, X.3
Gumperz, J.E.4
-
34
-
-
79956224825
-
Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor beta1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation
-
Ikeda, R., Ishii, K., Hoshikawa, Y., Azumi, J., Arakaki, Y., Yasui, T., Mat-suura, S., Matsumi, Y., Kono, Y., Mizuta, Y., Kurimasa, A., Hisatome, I., Friedman, S. L., Kawasaki, H., and Shiota, G. (2011). Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor beta1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation. Inflamm. Res. 60, 597-604.
-
(2011)
Inflamm. Res.
, vol.60
, pp. 597-604
-
-
Ikeda, R.1
Ishii, K.2
Hoshikawa, Y.3
Azumi, J.4
Arakaki, Y.5
Yasui, T.6
Mat-suura, S.7
Matsumi, Y.8
Kono, Y.9
Mizuta, Y.10
Kurimasa, A.11
Hisatome, I.12
Friedman, S.L.13
Kawasaki, H.14
Shiota, G.15
-
35
-
-
79956079647
-
CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice
-
Ishikawa, S., Ikejima, K., Yamagata, H., Aoyama,T., Kon,K.,Arai,K., Takeda, K., and Watanabe, S. (2011). CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice. J. Hepatol. 54, 1195-1204.
-
(2011)
J. Hepatol.
, vol.54
, pp. 1195-1204
-
-
Ishikawa, S.1
Ikejima, K.2
Yamagata, H.3
Aoyama, T.4
Kon, K.5
Arai, K.6
Takeda, K.7
Watanabe, S.8
-
36
-
-
33645218763
-
Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair
-
Jin, X., Zimmers, T. A., Perez, E. A., Pierce, R. H., Zhang, Z., and Koniaris, L. G. (2006). Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair. Hepatology 43, 474-484.
-
(2006)
Hepatology
, vol.43
, pp. 474-484
-
-
Jin, X.1
Zimmers, T.A.2
Perez, E.A.3
Pierce, R.H.4
Zhang, Z.5
Koniaris, L.G.6
-
37
-
-
56649083495
-
Mechanisms of disease progression in nonalcoholic fatty liver disease
-
Jou, J., Choi, S. S., and Diehl, A. M. (2008). Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin. Liver Dis. 28, 370-379.
-
(2008)
Semin. Liver Dis.
, vol.28
, pp. 370-379
-
-
Jou, J.1
Choi, S.S.2
Diehl, A.M.3
-
38
-
-
79957930356
-
Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats
-
Kaji, K., Yoshiji, H., Kitade, M., Ikenaka, Y., Noguchi, R., Shirai, Y., Aihara, Y., Namisaki, T., Yoshii, J., Yanase, K., Tsujimoto, T., Kawaratani, H., and Fukui, H. (2011). Combination treatment of angiotensin II type I receptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats. Am. J. Physiol. Gastrointest. Liver Physiol. 300, G1094-G1104.
-
(2011)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.300
-
-
Kaji, K.1
Yoshiji, H.2
Kitade, M.3
Ikenaka, Y.4
Noguchi, R.5
Shirai, Y.6
Aihara, Y.7
Namisaki, T.8
Yoshii, J.9
Yanase, K.10
Tsujimoto, T.11
Kawaratani, H.12
Fukui, H.13
-
39
-
-
34548249277
-
Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model
-
Kamada, Y., Matsumoto, H., Tamura, S., Fukushima, J., Kiso, S., Fukui, K., Igura, T., Maeda, N., Kihara, S., Funahashi, T., Matsuzawa, Y., Shi-momura, I., and Hayashi, N. (2007). Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model. J. Hepatol. 47, 556-564.
-
(2007)
J. Hepatol.
, vol.47
, pp. 556-564
-
-
Kamada, Y.1
Matsumoto, H.2
Tamura, S.3
Fukushima, J.4
Kiso, S.5
Fukui, K.6
Igura, T.7
Maeda, N.8
Kihara, S.9
Funahashi, T.10
Matsuzawa, Y.11
Shi-momura, I.12
Hayashi, N.13
-
40
-
-
10744228583
-
Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin
-
Kamada, Y., Tamura, S., Kiso, S., Mat-sumoto, H., Saji, Y., Yoshida, Y., Fukui, K., Maeda, N., Nishizawa, H., Nagaretani, H., Okamoto, Y., Kihara, S., Miyagawa, J., Shi-nomura, Y., Funahashi, T., and Matsuzawa, Y. (2003). Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin. Gastroenterology 125, 1796-1807.
-
(2003)
Gastroenterology
, vol.125
, pp. 1796-1807
-
-
Kamada, Y.1
Tamura, S.2
Kiso, S.3
Mat-sumoto, H.4
Saji, Y.5
Yoshida, Y.6
Fukui, K.7
Maeda, N.8
Nishizawa, H.9
Nagaretani, H.10
Okamoto, Y.11
Kihara, S.12
Miyagawa, J.13
Shi-nomura, Y.14
Funahashi, T.15
Matsuzawa, Y.16
-
41
-
-
12144290761
-
Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo
-
Kim, H. J., Higashimori, T., Park, S. Y., Choi, H., Dong, J., Kim, Y. J., Noh, H. L., Cho, Y. R., Cline, G., Kim, Y. B., and Kim, J. K. (2004). Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. Diabetes 53, 1060-1067.
-
(2004)
Diabetes
, vol.53
, pp. 1060-1067
-
-
Kim, H.J.1
Higashimori, T.2
Park, S.Y.3
Choi, H.4
Dong, J.5
Kim, Y.J.6
Noh, H.L.7
Cho, Y.R.8
Cline, G.9
Kim, Y.B.10
Kim, J.K.11
-
42
-
-
20044374023
-
Design and validation of a histo-logical scoring system for nonalcoholic fatty liver disease
-
Nonalcoholic Steatohepatitis Clinical Research Network
-
Kleiner, D. E., Brunt, E. M., Van Natta, M., Behling, C., Contos, M. J., Cum-mings, O. W., Ferrell,L. D., Liu,Y. C., Torbenson, M. S., Unalp-Arida, A., Yeh,M.,McCullough,A.J., Sanyal,A. J., and Nonalcoholic Steatohepatitis Clinical Research Network. (2005). Design and validation of a histo-logical scoring system for nonalcoholic fatty liver disease. Hepatology 41, 1313-1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
Behling, C.4
Contos, M.J.5
Cum-mings, O.W.6
Ferrell, L.D.7
Liu, Y.C.8
Torbenson, M.S.9
Unalp-Arida, A.10
Yeh, M.11
McCullough, A.J.12
Sanyal, A.J.13
-
43
-
-
70349416501
-
c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steato-sis to steatohepatitis and fibro-sis in mice
-
e1465
-
Kodama, Y., Kisseleva, T., Iwaisako, K., Miura, K., Taura, K., De Mini-cis, S., Osterreicher, C. H., Schn-abl, B., Seki, E., and Brenner, D. A. (2009). c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steato-sis to steatohepatitis and fibro-sis in mice. Gastroenterology 137, 1467-1477 e1465.
-
(2009)
Gastroenterology
, vol.137
, pp. 1467-1477
-
-
Kodama, Y.1
Kisseleva, T.2
Iwaisako, K.3
Miura, K.4
Taura, K.5
De Mini-cis, S.6
Osterreicher, C.H.7
Schn-abl, B.8
Seki, E.9
Brenner, D.A.10
-
44
-
-
79956301571
-
The role of oxidative stress in non-alcoholic steatohepatitis
-
Koek, G. H., Liedorp, P. R., and Bast, A. (2011). The role of oxidative stress in non-alcoholic steatohepatitis. Clin. Chim. Acta 412, 1297-1305.
-
(2011)
Clin. Chim. Acta
, vol.412
, pp. 1297-1305
-
-
Koek, G.H.1
Liedorp, P.R.2
Bast, A.3
-
45
-
-
77958103998
-
Nonalcoholic fatty liver disease
-
Krawczyk, M., Bonfrate, L., and Port-incasa, P. (2010). Nonalcoholic fatty liver disease. Best Pract. Res. Clin. Gastroenterol. 24, 695-708.
-
(2010)
Best Pract. Res. Clin. Gastroenterol.
, vol.24
, pp. 695-708
-
-
Krawczyk, M.1
Bonfrate, L.2
Port-incasa, P.3
-
46
-
-
73449142810
-
Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis
-
Kremer, M., Thomas, E., Milton, R. J., Perry, A. W., van Rooijen, N., Wheeler, M. D., Zacks, S., Fried, M., Rippe, R. A., and Hines, I. N. (2010). Kupffer cell and interleukin-12-dependent loss of natural killer T cells in hepatosteatosis. Hepatology 51, 130-141.
-
(2010)
Hepatology
, vol.51
, pp. 130-141
-
-
Kremer, M.1
Thomas, E.2
Milton, R.J.3
Perry, A.W.4
van Rooijen, N.5
Wheeler, M.D.6
Zacks, S.7
Fried, M.8
Rippe, R.A.9
Hines, I.N.10
-
47
-
-
79953269789
-
Liver vis-fatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery
-
Kukla, M., Ciupinska-Kajor, M., Kajor, M., Wylezol, M., Zwirska-Korczala, K., Hartleb, M., Berdowska, A., and Mazur, W. (2010a). Liver vis-fatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery. Pol. J. Pathol. 61, 147-153.
-
(2010)
Pol. J. Pathol.
, vol.61
, pp. 147-153
-
-
Kukla, M.1
Ciupinska-Kajor, M.2
Kajor, M.3
Wylezol, M.4
Zwirska-Korczala, K.5
Hartleb, M.6
Berdowska, A.7
Mazur, W.8
-
48
-
-
76749098030
-
Serum chemerin and vaspin in nonalcoholic fatty liver disease
-
Kukla, M., Zwirska-Korczala, K., Hartleb, M., Waluga, M., Chwist, A., Kajor, M., Ciupinska-Kajor, M., Berdowska, A., Wozniak-Grygiel, E., and Buldak, R. (2010b). Serum chemerin and vaspin in nonalcoholic fatty liver disease. Scand. J. Gastroenterol. 45, 235-242.
-
(2010)
Scand. J. Gastroenterol.
, vol.45
, pp. 235-242
-
-
Kukla, M.1
Zwirska-Korczala, K.2
Hartleb, M.3
Waluga, M.4
Chwist, A.5
Kajor, M.6
Ciupinska-Kajor, M.7
Berdowska, A.8
Wozniak-Grygiel, E.9
Buldak, R.10
-
49
-
-
82855168116
-
Potential role of leptin, adiponectin and the novel adipokines-visfatin, chemerin and vaspin-in chronic hepatitis
-
Kukla, M., Mazur, W., Buldak, R. J., and Zwirska-Korczala, K. (2011). Potential role of leptin, adiponectin and the novel adipokines-visfatin, chemerin and vaspin-in chronic hepatitis. Mol. Med. 17, 1397-1410.
-
(2011)
Mol. Med.
, vol.17
, pp. 1397-1410
-
-
Kukla, M.1
Mazur, W.2
Buldak, R.J.3
Zwirska-Korczala, K.4
-
50
-
-
78049452485
-
Nonalcoholic fatty liver disease
-
Law,K.,and Brunt,E.M.(2010). Nonalcoholic fatty liver disease. Clin. Liver Dis. 14, 591-604.
-
(2010)
Clin. Liver Dis.
, vol.14
, pp. 591-604
-
-
Law, K.1
Brunt, E.M.2
-
51
-
-
33845788135
-
Intrahepatic insulin resistance in a murine model of steatohepati-tis: effect of PPARgamma agonist pioglitazone
-
Leclercq, I. A., Lebrun, V. A., Starkel, P., and Horsmans, Y. J. (2007). Intrahepatic insulin resistance in a murine model of steatohepati-tis: effect of PPARgamma agonist pioglitazone. Lab. Invest. 87, 56-65.
-
(2007)
Lab. Invest.
, vol.87
, pp. 56-65
-
-
Leclercq, I.A.1
Lebrun, V.A.2
Starkel, P.3
Horsmans, Y.J.4
-
52
-
-
70449730945
-
Serum adipokine levels predictive of liver injury in nonalcoholic fatty liver disease
-
Lemoine, M., Ratziu, V., Kim, M., Maachi, M., Wendum, D., Paye, F., Bastard, J. P., Poupon, R., Hous-set, C., Capeau, J., and Serfaty, L. (2009). Serum adipokine levels predictive of liver injury in nonalcoholic fatty liver disease. Liver Int. 29, 1431-1438.
-
(2009)
Liver Int
, vol.29
, pp. 1431-1438
-
-
Lemoine, M.1
Ratziu, V.2
Kim, M.3
Maachi, M.4
Wendum, D.5
Paye, F.6
Bastard, J.P.7
Poupon, R.8
Hous-set, C.9
Capeau, J.10
Serfaty, L.11
-
53
-
-
79953898242
-
Reactive oxygen species released from hypoxic hepa-tocytes regulates MMP-2 expression in hepatic stellate cells
-
Li, J., Fan, R., Zhao, S., Liu, L., Guo, S., Wu, N., Zhang, W., and Chen, P. (2011). Reactive oxygen species released from hypoxic hepa-tocytes regulates MMP-2 expression in hepatic stellate cells. Int. J. Mol. Sci. 12, 2434-2447.
-
(2011)
Int. J. Mol. Sci.
, vol.12
, pp. 2434-2447
-
-
Li, J.1
Fan, R.2
Zhao, S.3
Liu, L.4
Guo, S.5
Wu, N.6
Zhang, W.7
Chen, P.8
-
54
-
-
78649759794
-
Inhibition of endothelin-1-mediated contraction of hepatic stellate cells by FXR ligand
-
doi:10.1371/journal.pone.0013955
-
Li, J., Kuruba, R., Wilson, A., Gao, X., Zhang, Y., and Li, S. (2010). Inhibition of endothelin-1-mediated contraction of hepatic stellate cells by FXR ligand. PLoS ONE 5, e13955. doi:10.1371/journal.pone.0013955
-
(2010)
PLoS ONE
, vol.5
-
-
Li, J.1
Kuruba, R.2
Wilson, A.3
Gao, X.4
Zhang, Y.5
Li, S.6
-
55
-
-
25844437136
-
Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease
-
Li, Z., Soloski, M. J., and Diehl, A. M. (2005). Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. Hepatology 42, 880-885.
-
(2005)
Hepatology
, vol.42
, pp. 880-885
-
-
Li, Z.1
Soloski, M.J.2
Diehl, A.M.3
-
56
-
-
81355146801
-
The liver X receptor in hepatic stellate cells: a novel antifibrogenic target?
-
Mallat, A., and Lotersztajn, S. (2011). The liver X receptor in hepatic stellate cells: a novel antifibrogenic target? J. Hepatol. 55, 1452-1454.
-
(2011)
J Hepatol
, vol.55
, pp. 1452-1454
-
-
Mallat, A.1
Lotersztajn, S.2
-
57
-
-
27644476962
-
Review article: the pathogenesis of fibrosis in non-alcoholic steatohepatitis
-
Marra, F., Aleffi, S., Bertolani, C., Petrai, I., and Vizzutti, F. (2005). Review article: the pathogenesis of fibrosis in non-alcoholic steatohepatitis. Aliment. Pharmacol. Ther. 22(Suppl. 2), 44-47.
-
(2005)
Aliment. Pharmacol. Ther.
, vol.22
, Issue.SUPPL. 2
, pp. 44-47
-
-
Marra, F.1
Aleffi, S.2
Bertolani, C.3
Petrai, I.4
Vizzutti, F.5
-
58
-
-
70349238777
-
Adipokines in liver diseases
-
Marra, F., and Bertolani, C. (2009). Adipokines in liver diseases. Hepa-tology 50, 957-969.
-
(2009)
Hepa-tology
, vol.50
, pp. 957-969
-
-
Marra, F.1
Bertolani, C.2
-
59
-
-
80052448815
-
Modulation of liver fibrosis by adipokines
-
Marra, F., Navari, N., Vivoli, E., Galas-tri, S., and Provenzano, A. (2011). Modulation of liver fibrosis by adipokines. Dig. Dis. 29, 371-376.
-
(2011)
Dig. Dis.
, vol.29
, pp. 371-376
-
-
Marra, F.1
Navari, N.2
Vivoli, E.3
Galas-tri, S.4
Provenzano, A.5
-
60
-
-
77956022643
-
Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis
-
Matsunami, T., Sato, Y., Ariga, S., Sato, T., Kashimura, H., Hasegawa, Y., and Yukawa, M. (2010). Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. Int. J. Clin. Exp. Pathol. 3, 472-481.
-
(2010)
Int. J. Clin. Exp. Pathol.
, vol.3
, pp. 472-481
-
-
Matsunami, T.1
Sato, Y.2
Ariga, S.3
Sato, T.4
Kashimura, H.5
Hasegawa, Y.6
Yukawa, M.7
-
61
-
-
80052615251
-
Full-spectrum antioxidant therapy featuring astax-anthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease
-
McCarty, M. F. (2011). Full-spectrum antioxidant therapy featuring astax-anthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease. Med. Hypotheses 77, 550-556.
-
(2011)
Med. Hypotheses
, vol.77
, pp. 550-556
-
-
McCarty, M.F.1
-
62
-
-
78649938445
-
Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease
-
Medici, V., Ali, M. R., Seo, S., Aoki, C. A., Rossaro, L., Kim, K., Fuller, W. D., Vidovszky, T. J., Smith, W., Jiang, J. X., Maganti, K., Havel, P. J., Kamboj, A., Ramsamooj, R., and Török, N. J. (2010). Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease. Obesity (Silver Spring) 18, 2268-2273.
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 2268-2273
-
-
Medici, V.1
Ali, M.R.2
Seo, S.3
Aoki, C.A.4
Rossaro, L.5
Kim, K.6
Fuller, W.D.7
Vidovszky, T.J.8
Smith, W.9
Jiang, J.X.10
Maganti, K.11
Havel, P.J.12
Kamboj, A.13
Ramsamooj, R.14
Török, N.J.15
-
63
-
-
77953891627
-
Toll-like receptor 9 promotes steatohepati-tis by induction of interleukin-1beta in mice
-
Miura, K., Kodama, Y., Inokuchi, S., Schnabl, B., Aoyama, T., Ohnishi, H., Olefsky, J. M., Brenner, D. A., and Seki, E. (2010). Toll-like receptor 9 promotes steatohepati-tis by induction of interleukin-1beta in mice. Gastroenterology 139, 323-334 e327.
-
(2010)
Gastroenterology
, vol.139
, pp. 323-334
-
-
Miura, K.1
Kodama, Y.2
Inokuchi, S.3
Schnabl, B.4
Aoyama, T.5
Ohnishi, H.6
Olefsky, J.M.7
Brenner, D.A.8
Seki, E.9
-
64
-
-
84855216732
-
Nifedipine prevents hepatic fibrosis in a nonalcoholic steatohepatitis
-
Nakagami, H., Shimamura, M., Miyake, T., Shimosato, T., Minobe, N., Mori-tani, T., Kiomy Osako, M., Nak-agami, F., Koriyama, H., Kyutoku, M., Shimizu, H., Katsuya, T., and Morishita,R.(2012). Nifedipine prevents hepatic fibrosis in a nonalcoholic steatohepatitis. Mol. Med. Report 5, 37-40.
-
(2012)
Mol. Med. Report
, vol.5
, pp. 37-40
-
-
Nakagami, H.1
Shimamura, M.2
Miyake, T.3
Shimosato, T.4
Minobe, N.5
Mori-tani, T.6
Kiomy Osako, M.7
Nak-agami, F.8
Koriyama, H.9
Kyutoku, M.10
Shimizu, H.11
Katsuya, T.12
Morishita, R.13
-
65
-
-
33947264902
-
Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similartononalcoholic steatohepati-tis
-
Nakayama, H., Otabe, S., Ueno, T., Hirota, N., Yuan, X., Fukutani, T., Hashinaga, T., Wada, N., and Yamada, K. (2007). Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similartononalcoholic steatohepati-tis. Metab. Clin. Exp. 56, 470-475.
-
(2007)
Metab. Clin. Exp.
, vol.56
, pp. 470-475
-
-
Nakayama, H.1
Otabe, S.2
Ueno, T.3
Hirota, N.4
Yuan, X.5
Fukutani, T.6
Hashinaga, T.7
Wada, N.8
Yamada, K.9
-
66
-
-
33846253661
-
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis
-
Ota, T., Takamura, T., Kurita, S., Mat-suzawa, N., Kita, Y., Uno, M., Aka-hori, H., Misu, H., Sakurai, M., Zen, Y., Nakanuma, Y., and Kaneko, S. (2007). Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. Gastroenterol-ogy 132, 282-293.
-
(2007)
Gastroenterol-ogy
, vol.132
, pp. 282-293
-
-
Ota, T.1
Takamura, T.2
Kurita, S.3
Mat-suzawa, N.4
Kita, Y.5
Uno, M.6
Aka-hori, H.7
Misu, H.8
Sakurai, M.9
Zen, Y.10
Nakanuma, Y.11
Kaneko, S.12
-
67
-
-
0034802171
-
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibro-sis in nonalcoholic steatohepatitis
-
Paradis, V., Perlemuter, G., Bonvoust, F., Dargere, D., Parfait, B., Vidaud, M., Conti, M., Huet, S., Ba, N., Buffet, C., and Bedossa, P. (2001). High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibro-sis in nonalcoholic steatohepatitis. Hepatology 34, 738-744.
-
(2001)
Hepatology
, vol.34
, pp. 738-744
-
-
Paradis, V.1
Perlemuter, G.2
Bonvoust, F.3
Dargere, D.4
Parfait, B.5
Vidaud, M.6
Conti, M.7
Huet, S.8
Ba, N.9
Buffet, C.10
Bedossa, P.11
-
68
-
-
79960109765
-
Pathophysiology of non-alcoholic steatohepatitis and basis for treatment
-
Pinzani, M. (2011). Pathophysiology of non-alcoholic steatohepatitis and basis for treatment. Dig. Dis. 29, 243-248.
-
(2011)
Dig. Dis.
, vol.29
, pp. 243-248
-
-
Pinzani, M.1
-
69
-
-
77952049390
-
The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease
-
Polyzos, S. A., Kountouras, J., Zavos, C., and Tsiaousi, E. (2010). The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease. Diabetes Obes. Metab. 12, 365-383.
-
(2010)
Diabetes Obes. Metab.
, vol.12
, pp. 365-383
-
-
Polyzos, S.A.1
Kountouras, J.2
Zavos, C.3
Tsiaousi, E.4
-
70
-
-
1442355447
-
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
-
Promrat, K., Lutchman, G., Uwaifo, G. I., Freedman, R. J., Soza, A., Heller, T., Doo, E., Ghany, M., Premkumar, A., Park, Y., Liang, T. J., Yanovski, J. A., Kleiner, D. E., and Hoofna-gle, J. H. (2004). A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 39, 188-196.
-
(2004)
Hepatology
, vol.39
, pp. 188-196
-
-
Promrat, K.1
Lutchman, G.2
Uwaifo, G.I.3
Freedman, R.J.4
Soza, A.5
Heller, T.6
Doo, E.7
Ghany, M.8
Premkumar, A.9
Park, Y.10
Liang, T.J.11
Yanovski, J.A.12
Kleiner, D.E.13
Hoofna-gle, J.H.14
-
71
-
-
75449116707
-
Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosigli-tazone therapy (FLIRT 2) extension trial
-
LIDO Study Group
-
Ratziu, V., Charlotte, F., Bernhardt, C., Giral, P., Halbron, M., Lenaour, G., Hartmann-Heurtier, A., Bruck-ert, E., Poynard, T., and LIDO Study Group. (2010). Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosigli-tazone therapy (FLIRT 2) extension trial. Hepatology 51, 445-453.
-
(2010)
Hepatology
, vol.51
, pp. 445-453
-
-
Ratziu, V.1
Charlotte, F.2
Bernhardt, C.3
Giral, P.4
Halbron, M.5
Lenaour, G.6
Hartmann-Heurtier, A.7
Bruck-ert, E.8
Poynard, T.9
-
72
-
-
46349088361
-
Rosiglita-zone for nonalcoholic steatohep-atitis: one-year results of the randomized placebo-controlled fatty liver improvement with rosiglita-zone therapy (FLIRT) trial
-
LIDO Study Group
-
Ratziu, V., Giral, P., Jacqueminet, S., Charlotte, F., Hartemann-Heurtier, A., Serfaty, L., Podevin, P., Lacorte, J. M., Bernhardt, C., Bruckert, E., Grimaldi, A., Poynard, T., and LIDO Study Group. (2008). Rosiglita-zone for nonalcoholic steatohep-atitis: one-year results of the randomized placebo-controlled fatty liver improvement with rosiglita-zone therapy (FLIRT) trial. Gas-troenterology 135, 100-110.
-
(2008)
Gas-troenterology
, vol.135
, pp. 100-110
-
-
Ratziu, V.1
Giral, P.2
Jacqueminet, S.3
Charlotte, F.4
Hartemann-Heurtier, A.5
Serfaty, L.6
Podevin, P.7
Lacorte, J.M.8
Bernhardt, C.9
Bruckert, E.10
Grimaldi, A.11
Poynard, T.12
-
73
-
-
79956197013
-
SHP-dependent andctivated receptor-gamma by the bile acid sensor farnesoid X receptor counter-ry henotype of liver myofibroblasts
-
Renga, B., Mencarelli, A., Migliorati, M., Cipriani, S., D'Amore, C., Distrutti, E., and Fiorucci, S. (2011). SHP-dependent andctivated receptor-gamma by the bile acid sensor farnesoid X receptor counter-ry henotype of liver myofibroblasts. Inflamm. Res. 60, 577-587.
-
(2011)
Inflamm. Res.
, vol.60
, pp. 577-587
-
-
Renga, B.1
Mencarelli, A.2
Migliorati, M.3
Cipriani, S.4
D'Amore, C.5
Distrutti, E.6
Fiorucci, S.7
-
74
-
-
0346689994
-
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
-
Rinella, M. E., and Green, R. M. (2004). The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J. Hepatol. 40, 47-51.
-
(2004)
J. Hepatol.
, vol.40
, pp. 47-51
-
-
Rinella, M.E.1
Green, R.M.2
-
75
-
-
77952573691
-
Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohep-atitis
-
Rombouts, K., and Marra, F. (2010). Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohep-atitis. Dig. Dis. 28, 229-235.
-
(2010)
Dig. Dis.
, vol.28
, pp. 229-235
-
-
Rombouts, K.1
Marra, F.2
-
76
-
-
3042550624
-
Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohep-atitis in a dietary murine model
-
Sahai, A., Malladi, P., Melin-Aldana, H., Green, R. M., and Whitington, P. F. (2004). Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohep-atitis in a dietary murine model. Am. J. Physiol. Gastrointest. Liver Physiol. 287, G264-G273.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.287
-
-
Sahai, A.1
Malladi, P.2
Melin-Aldana, H.3
Green, R.M.4
Whitington, P.F.5
-
77
-
-
78649459634
-
Study of adiponectin in chronic liver disease and cholestasis
-
Salman, T. A., Allam, N., Azab, G. I., Shaarawy, A. A., Hassouna, M. M., and El-Haddad, O. M. (2010). Study of adiponectin in chronic liver disease and cholestasis. Hepatol. Int. 4, 767-774.
-
(2010)
Hepatol. Int.
, vol.4
, pp. 767-774
-
-
Salman, T.A.1
Allam, N.2
Azab, G.I.3
Shaarawy, A.A.4
Hassouna, M.M.5
El-Haddad, O.M.6
-
78
-
-
14944359845
-
A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepati-tis
-
Sanyal,A. J., Mofrad, P. S., Contos, M. J., Sargeant, C., Luketic, V. A., Sterling, R. K., Stravitz, R. T., Shiffman, M. L., Clore, J., and Mills, A. S. (2004). A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepati-tis. Clin. Gastroenterol. Hepatol. 2, 1107-1115.
-
(2004)
Clin. Gastroenterol. Hepatol.
, vol.2
, pp. 1107-1115
-
-
Sanyal, A.J.1
Mofrad, P.S.2
Contos, M.J.3
Sargeant, C.4
Luketic, V.A.5
Sterling, R.K.6
Stravitz, R.T.7
Shiffman, M.L.8
Clore, J.9
Mills, A.S.10
-
79
-
-
77952562217
-
Animal models of nonalcoholic steatohepatitis: of mice and man
-
Schattenberg, J. M., and Galle, P. R. (2010). Animal models of nonalcoholic steatohepatitis: of mice and man. Dig. Dis. 28, 247-254.
-
(2010)
Dig. Dis.
, vol.28
, pp. 247-254
-
-
Schattenberg, J.M.1
Galle, P.R.2
-
80
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
Seki, E., De Minicis, S., Osterreicher, C. H., Kluwe, J., Osawa, Y., Brenner, D. A., and Schwabe, R. F. (2007). TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat. Med. 13, 1324-1332.
-
(2007)
Nat. Med.
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
De Minicis, S.2
Osterreicher, C.H.3
Kluwe, J.4
Osawa, Y.5
Brenner, D.A.6
Schwabe, R.F.7
-
81
-
-
77954471976
-
Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery
-
Sell, H., Divoux, A., Poitou, C., Bas-devant, A., Bouillot, J. L., Bedossa, P., Tordjman, J., Eckel, J., and Clé-ment, K. (2010). Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery. J. Clin. Endocrinol. Metab. 95, 2892-2896.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, pp. 2892-2896
-
-
Sell, H.1
Divoux, A.2
Poitou, C.3
Bas-devant, A.4
Bouillot, J.L.5
Bedossa, P.6
Tordjman, J.7
Eckel, J.8
Clé-ment, K.9
-
82
-
-
77952730087
-
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease
-
Syn, W. K., Oo, Y. H., Pereira, T. A., Karaca, G. F., Jung, Y., Omenetti, A., Witek, R. P., Choi, S. S., Guy, C. D., Fearing, C. M., Teaberry, V., Pereira, F. E., Adams, D. H., and Diehl, A. M. (2010). Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease. Hepatology 51, 1998-2007.
-
(2010)
Hepatology
, vol.51
, pp. 1998-2007
-
-
Syn, W.K.1
Oo, Y.H.2
Pereira, T.A.3
Karaca, G.F.4
Jung, Y.5
Omenetti, A.6
Witek, R.P.7
Choi, S.S.8
Guy, C.D.9
Fearing, C.M.10
Teaberry, V.11
Pereira, F.E.12
Adams, D.H.13
Diehl, A.M.14
-
83
-
-
67649669912
-
Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogen-esis of nonalcoholic fatty liver disease
-
Tajiri, K., Shimizu, Y., Tsuneyama, K., and Sugiyama, T. (2009). Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogen-esis of nonalcoholic fatty liver disease. Eur. J. Gastroenterol. Hepatol. 21, 673-680.
-
(2009)
Eur. J. Gastroenterol. Hepatol.
, vol.21
, pp. 673-680
-
-
Tajiri, K.1
Shimizu, Y.2
Tsuneyama, K.3
Sugiyama, T.4
-
84
-
-
79959547264
-
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis
-
Tarrats, N., Moles, A., Morales, A., Garcia-Ruiz, C., Fernandez-Checa, J. C., and Mari, M. (2011). Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis. Hepatology 54, 319-327.
-
(2011)
Hepatology
, vol.54
, pp. 319-327
-
-
Tarrats, N.1
Moles, A.2
Morales, A.3
Garcia-Ruiz, C.4
Fernandez-Checa, J.C.5
Mari, M.6
-
85
-
-
78049522194
-
Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis
-
Tilg, H., and Moschen, A. R. (2010). Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. Hepa-tology 52, 1836-1846.
-
(2010)
Hepa-tology
, vol.52
, pp. 1836-1846
-
-
Tilg, H.1
Moschen, A.R.2
-
86
-
-
31044450728
-
Mechanisms of liver fibrosis
-
Tsukada, S., Parsons, C. J., and Rippe, R. A. (2006). Mechanisms of liver fibrosis. Clin. Chim. Acta 364, 33-60.
-
(2006)
Clin. Chim. Acta
, vol.364
, pp. 33-60
-
-
Tsukada, S.1
Parsons, C.J.2
Rippe, R.A.3
-
87
-
-
54549111991
-
Oxidative and nitrosative stress and fibro-genic response
-
Urtasun, R., Conde de la Rosa, L., and Nieto, N. (2008). Oxidative and nitrosative stress and fibro-genic response. Clin. Liver Dis. 12, 769-790.
-
(2008)
Clin. Liver Dis.
, vol.12
, pp. 769-790
-
-
Urtasun, R.1
Conde de la Rosa, L.2
Nieto, N.3
-
88
-
-
0033636915
-
Serum leptin levels in patients with nonalcoholic steatohepatitis
-
Uygun, A., Kadayifci, A., Yesilova, Z., Erdil, A., Yaman, H., Saka, M., Deveci, M. S., Bagci, S., Gulsen, M., Karaeren, N., and Dagalp, K. (2000). Serum leptin levels in patients with nonalcoholic steatohepatitis. Am. J. Gastroenterol. 95, 3584-3589.
-
(2000)
Am. J. Gastroenterol.
, vol.95
, pp. 3584-3589
-
-
Uygun, A.1
Kadayifci, A.2
Yesilova, Z.3
Erdil, A.4
Yaman, H.5
Saka, M.6
Deveci, M.S.7
Bagci, S.8
Gulsen, M.9
Karaeren, N.10
Dagalp, K.11
-
89
-
-
37149031874
-
Hepatic stellate cells and alcoholic liver disease
-
Vera, M., and Nieto, N. (2006). Hepatic stellate cells and alcoholic liver disease. Rev. Esp. Enferm. Dig. 98, 674-684.
-
(2006)
Rev. Esp. Enferm. Dig.
, vol.98
, pp. 674-684
-
-
Vera, M.1
Nieto, N.2
-
90
-
-
79952227694
-
Nuclear receptors in liver disease
-
Wagner, M., Zollner, G., and Trauner, M. (2011). Nuclear receptors in liver disease. Hepatology 53, 1023-1034.
-
(2011)
Hepatology
, vol.53
, pp. 1023-1034
-
-
Wagner, M.1
Zollner, G.2
Trauner, M.3
-
91
-
-
36348997503
-
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9
-
Watanabe, A., Hashmi, A., Gomes, D. A., Town, T., Badou, A., Flavell, R. A., and Mehal, W. Z. (2007). Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology 46, 1509-1518.
-
(2007)
Hepatology
, vol.46
, pp. 1509-1518
-
-
Watanabe, A.1
Hashmi, A.2
Gomes, D.A.3
Town, T.4
Badou, A.5
Flavell, R.A.6
Mehal, W.Z.7
-
92
-
-
78650486196
-
Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study
-
Williams, C. D., Stengel, J., Asike, M. I., Torres, D. M., Shaw, J., Contr-eras, M., Landt, C. L., and Harrison, S. A. (2011). Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study. Gastroenterology 140, 124-131.
-
(2011)
Gastroenterology
, vol.140
, pp. 124-131
-
-
Williams, C.D.1
Stengel, J.2
Asike, M.I.3
Torres, D.M.4
Shaw, J.5
Contr-eras, M.6
Landt, C.L.7
Harrison, S.A.8
-
93
-
-
79960212414
-
Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease
-
Yilmaz, Y., Kurt, R., Gurdal, A., Alahdab, Y. O., Yonal, O., Senates, E., Polat, N., Eren, F., Imeryuz, N., and Oflaz, H. (2011a). Circulating vaspin levels and epicardial adipose tissue thickness are associated with impaired coronary flow reserve in patients with nonalcoholic fatty liver disease. Atherosclerosis 217, 125-129.
-
(2011)
Atherosclerosis
, vol.217
, pp. 125-129
-
-
Yilmaz, Y.1
Kurt, R.2
Gurdal, A.3
Alahdab, Y.O.4
Yonal, O.5
Senates, E.6
Polat, N.7
Eren, F.8
Imeryuz, N.9
Oflaz, H.10
-
94
-
-
78651368690
-
Serum levels of omentin, chemerin and adipsin in patients with biopsy-proven nonalcoholic fatty liver disease
-
Yilmaz, Y., Yonal, O., Kurt, R., Alahdab, Y. O., Eren, F., Ozdogan, O., Celikel, C. A., Imeryuz, N., Kalayci, C., and Avsar, E. (2011b). Serum levels of omentin, chemerin and adipsin in patients with biopsy-proven nonalcoholic fatty liver disease. Scand. J. Gastroenterol. 46, 91-97
-
(2011)
Scand. J. Gastroenterol.
, vol.46
, pp. 91-97
-
-
Yilmaz, Y.1
Yonal, O.2
Kurt, R.3
Alahdab, Y.O.4
Eren, F.5
Ozdogan, O.6
Celikel, C.A.7
Imeryuz, N.8
Kalayci, C.9
Avsar, E.10
-
95
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Fried-man,J. M. (1994). Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Fried-man, J.M.6
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