Inhibition of endothelin-1-mediated contraction of hepatic stellate cells by FXR ligand

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Li, Jiang ^a   Kuruba, Ramalinga ^a   Wilson, Annette ^a   Gao, Xiang ^a   Zhang, Yifei ^a   Li, Song ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; ENDOTHELIN 1; FARNESOID X RECEPTOR; RHO FACTOR; ACTIN BINDING PROTEIN; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; ISOXAZOLE DERIVATIVE; MOESIN; RHO KINASE;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL CYCLE ARREST; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; MALE; MOLECULAR MECHANICS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; STELLATE CELL; UPREGULATION; ANIMAL; CELL CULTURE; CELL SHAPE; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL SHAPE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; ENDOTHELIN-1; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; ISOXAZOLES; MALE; MICROFILAMENT PROTEINS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION;

EID: 78649759794     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013955     Document Type: Article

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