메뉴 건너뛰기




Volumn 287, Issue 38, 2012, Pages 31920-31928

Polycomb (PcG) proteins, BMI1 and SUZ12, regulate arsenic-induced cell transformation

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; METHYLATION; PROTEINS; TISSUE CULTURE; TUMORS;

EID: 84866370633     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.360362     Document Type: Article
Times cited : (35)

References (46)
  • 1
    • 0033525607 scopus 로고    scopus 로고
    • Arsenic and drinking water contamination
    • Gebel, T. W. (1999) Arsenic and drinking water contamination. Science 283, 1458-1459
    • (1999) Science , vol.283 , pp. 1458-1459
    • Gebel, T.W.1
  • 2
    • 77954353627 scopus 로고    scopus 로고
    • The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite
    • Li, Y., Ling, M., Xu, Y., Wang, S., Li, Z., Zhou, J., Wang, X., and Liu, Q. (2010) The repressive effect of NF-kappaB on p53 by mot-2 is involved in human keratinocyte transformation induced by low levels of arsenite. Toxicol. Sci. 116, 174-182
    • (2010) Toxicol. Sci. , vol.116 , pp. 174-182
    • Li, Y.1    Ling, M.2    Xu, Y.3    Wang, S.4    Li, Z.5    Zhou, J.6    Wang, X.7    Liu, Q.8
  • 3
  • 5
    • 22544437866 scopus 로고    scopus 로고
    • Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: Aberrant genomic DNA methylation and K-ras oncogene activation
    • DOI 10.1016/j.taap.2004.11.017, PII S0041008X0400540X
    • Benbrahim-Tallaa, L., Waterland, R. A., Styblo, M., Achanzar, W. E., Webber, M. M., and Waalkes, M. P. (2005) Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation. Toxicol. Appl. Pharmacol. 206, 288-298 (Pubitemid 41020671)
    • (2005) Toxicology and Applied Pharmacology , vol.206 , Issue.3 , pp. 288-298
    • Benbrahim-Tallaa, L.1    Waterland, R.A.2    Styblo, M.3    Achanzar, W.E.4    Webber, M.M.5    Waalkes, M.P.6
  • 6
    • 33847055846 scopus 로고    scopus 로고
    • Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells
    • Benbrahim-Tallaa, L., Webber, M. M., and Waalkes, M. P. (2007) Mechanisms of acquired androgen independence during arsenic-induced malignant transformation of human prostate epithelial cells. Environ. Health Perspect. 115, 243-247
    • (2007) Environ. Health Perspect. , vol.115 , pp. 243-247
    • Benbrahim-Tallaa, L.1    Webber, M.M.2    Waalkes, M.P.3
  • 7
    • 0033591215 scopus 로고    scopus 로고
    • Requirement of Erk, but not JNK, for arsenite-induced cell transformation
    • Huang, C., Ma, W. Y., Li, J., Goranson, A., and Dong, Z. (1999) Requirement of Erk, but not JNK, for arsenite-induced cell transformation. J. Biol. Chem. 274, 14595-14601
    • (1999) J. Biol. Chem. , vol.274 , pp. 14595-14601
    • Huang, C.1    Ma, W.Y.2    Li, J.3    Goranson, A.4    Dong, Z.5
  • 8
    • 33751011904 scopus 로고    scopus 로고
    • Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells
    • DOI 10.1016/j.taap.2006.06.006, PII S0041008X06002055
    • Liu, J., Benbrahim-Tallaa, L., Qian, X., Yu, L., Xie, Y., Boos, J., Qu, W., and Waalkes, M. P. (2006) Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells. Toxicol. Appl. Pharmacol. 216, 407-415 (Pubitemid 44739945)
    • (2006) Toxicology and Applied Pharmacology , vol.216 , Issue.3 , pp. 407-415
    • Liu, J.1    Benbrahim-Tallaa, L.2    Qian, X.3    Yu, L.4    Xie, Y.5    Boos, J.6    Qu, W.7    Waalkes, M.P.8
  • 9
    • 13244279419 scopus 로고    scopus 로고
    • Role of polycomb group proteins in stem cell self-renewal and cancer
    • DOI 10.1089/dna.2005.24.117
    • Gil, J., Bernard, D., and Peters, G. (2005) Role of polycomb group proteins in stem cell self-renewal and cancer. DNA Cell Biol. 24, 117-125 (Pubitemid 40189747)
    • (2005) DNA and Cell Biology , vol.24 , Issue.2 , pp. 117-125
    • Gil, J.1    Bernard, D.2    Peters, G.3
  • 10
    • 0025727771 scopus 로고
    • Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice
    • Haupt, Y., Alexander, W. S., Barri, G., Klinken, S. P., and Adams, J. M. (1991) Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65, 753-763 (Pubitemid 121001307)
    • (1991) Cell , vol.65 , Issue.5 , pp. 753-763
    • Haupt, Y.1    Alexander, W.S.2    Barri, G.3    Klinken, S.P.4    Adams, J.M.5
  • 11
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • DOI 10.1038/nature01572
    • Lessard, J., and Sauvageau, G. (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423, 255-260 (Pubitemid 40852690)
    • (2003) Nature , vol.423 , Issue.6937 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 12
    • 8844265508 scopus 로고    scopus 로고
    • Epigenetic regulation of cellular memory by the polycomb and trithorax group proteins
    • DOI 10.1146/annurev.genet.38.072902.091907
    • Ringrose, L., and Paro, R. (2004) Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu. Rev. Genet. 38, 413-443 (Pubitemid 40013734)
    • (2004) Annual Review of Genetics , vol.38 , pp. 413-443
    • Ringrose, L.1    Paro, R.2
  • 13
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • DOI 10.1038/sj.emboj.7600402
    • Pasini, D., Bracken, A. P., Jensen, M. R., Lazzerini Denchi, E., and Helin, K. (2004) Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23, 4061-4071 (Pubitemid 39472427)
    • (2004) EMBO Journal , vol.23 , Issue.20 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Denchi, E.L.4    Helin, K.5
  • 14
    • 0141576562 scopus 로고    scopus 로고
    • Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy
    • Kirmizis, A., Bartley, S. M., and Farnham, P. J. (2003) Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy. Mol. Cancer Ther. 2, 113-121
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 113-121
    • Kirmizis, A.1    Bartley, S.M.2    Farnham, P.J.3
  • 15
    • 0035141264 scopus 로고    scopus 로고
    • The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding p55 and the histone deacetylase RPD3
    • Tie, F., Furuyama, T., Prasad-Sinha, J., Jane, E., and Harte, P. J. (2001) The Drosophila Polycomb Group proteins ESC and E(Z) are present in a complex containing the histone-binding protein p55 and the histone deacetylase RPD3. Development 128, 275-286 (Pubitemid 32124152)
    • (2001) Development , vol.128 , Issue.2 , pp. 275-286
    • Tie, F.1    Furuyama, T.2    Prasad-Sinha, J.3    Jane, E.4    Harte, P.J.5
  • 16
    • 33747587608 scopus 로고    scopus 로고
    • Regulation of the INK4b-ARF-INK4a tumour suppressor locus: All for one or one for all
    • DOI 10.1038/nrm1987, PII NRM1987
    • Gil, J., and Peters, G. (2006) Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat. Rev. Mol. Cell Biol. 7, 667-677 (Pubitemid 44268212)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.9 , pp. 667-677
    • Gil, J.1    Peters, G.2
  • 18
    • 42049108200 scopus 로고    scopus 로고
    • Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation
    • DOI 10.1158/0008-5472.CAN-07-6597
    • Kim, H. G., Lee, K. W., Cho, Y. Y., Kang, N. J., Oh, S. M., Bode, A. M., and Dong, Z. (2008) Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer Res. 68, 2538-2547 (Pubitemid 351521831)
    • (2008) Cancer Research , vol.68 , Issue.7 , pp. 2538-2547
    • Kim, H.-G.1    Ki, W.L.2    Cho, Y.-Y.3    Nam, J.K.4    Oh, S.-M.5    Bode, A.M.6    Dong, Z.7
  • 19
    • 77954758157 scopus 로고    scopus 로고
    • Polycomb group protein-mediated repression of transcription
    • Morey, L., and Helin, K. (2010) Polycomb group protein-mediated repression of transcription. Trends Biochem. Sci. 35, 323-332
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 323-332
    • Morey, L.1    Helin, K.2
  • 22
    • 40949115930 scopus 로고    scopus 로고
    • PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation
    • Ouyang, W., Luo, W., Zhang, D., Jian, J., Ma, Q., Li, J., Shi, X., Chen, J., Gao, J., and Huang, C. (2008) PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation. Environ. Health Perspect. 116, 1-6
    • (2008) Environ. Health Perspect. , vol.116 , pp. 1-6
    • Ouyang, W.1    Luo, W.2    Zhang, D.3    Jian, J.4    Ma, Q.5    Li, J.6    Shi, X.7    Chen, J.8    Gao, J.9    Huang, C.10
  • 23
    • 56449115368 scopus 로고    scopus 로고
    • Induction of cytoplasmic accumulation of p53: A mechanism for low levels of arsenic exposure to predispose cells for malignant transformation
    • Huang, Y., Zhang, J., McHenry, K. T., Kim, M. M., Zeng, W., Lopez- Pajares, V., Dibble, C. C., Mizgerd, J. P., and Yuan, Z. M. (2008) Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation. Cancer Res. 68, 9131-9136
    • (2008) Cancer Res. , vol.68 , pp. 9131-9136
    • Huang, Y.1    Zhang, J.2    McHenry, K.T.3    Kim, M.M.4    Zeng, W.5    Lopez-Pajares, V.6    Dibble, C.C.7    Mizgerd, J.P.8    Yuan, Z.M.9
  • 24
    • 0015861335 scopus 로고
    • A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB-3T3
    • Kakunaga, T. (1973) A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB-3T3. Int. J. Cancer 12, 463-473
    • (1973) Int. J. Cancer , vol.12 , pp. 463-473
    • Kakunaga, T.1
  • 25
    • 64549122358 scopus 로고    scopus 로고
    • Comparison of sensitivity to arsenic compounds between a Bhas 42 cell transformation assay and a BALB/c 3T3 cell transformation assay
    • Muramatsu, D., Sasaki, K., Kuroda, S., Hayashi, K., Tanaka, N., and Sakai, A. (2009) Comparison of sensitivity to arsenic compounds between a Bhas 42 cell transformation assay and a BALB/c 3T3 cell transformation assay. Mutat. Res. 675, 66-70
    • (2009) Mutat. Res. , vol.675 , pp. 66-70
    • Muramatsu, D.1    Sasaki, K.2    Kuroda, S.3    Hayashi, K.4    Tanaka, N.5    Sakai, A.6
  • 26
    • 33744827997 scopus 로고    scopus 로고
    • INK4a and RASSF1A and induces lung cancer in A/J mice
    • DOI 10.1093/toxsci/kfj159
    • Cui, X., Wakai, T., Shirai, Y., Hatakeyama, K., and Hirano, S. (2006b) Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice. Toxicol. Sci. 91, 372-381 (Pubitemid 43827290)
    • (2006) Toxicological Sciences , vol.91 , Issue.2 , pp. 372-381
    • Cui, X.1    Wakai, T.2    Shirai, Y.3    Hatakeyama, K.4    Hirano, S.5
  • 27
    • 33244462831 scopus 로고    scopus 로고
    • Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells
    • DOI 10.1016/j.humpath.2005.10.013, PII S0046817705006064
    • Cui, X., Wakai, T., Shirai, Y., Yokoyama, N., Hatakeyama, K., and Hirano, S. (2006a) Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells. Hum. Pathol. 37, 298-311 (Pubitemid 43277518)
    • (2006) Human Pathology , vol.37 , Issue.3 , pp. 298-311
    • Cui, X.1    Wakai, T.2    Shirai, Y.3    Yokoyama, N.4    Hatakeyama, K.5    Hirano, S.6
  • 28
    • 77954107743 scopus 로고    scopus 로고
    • Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
    • Reichard, J. F., and Puga, A. (2010) Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics 2, 87-104
    • (2010) Epigenomics , vol.2 , pp. 87-104
    • Reichard, J.F.1    Puga, A.2
  • 29
    • 49649083174 scopus 로고    scopus 로고
    • Arsenite alters global histone H3 methylation
    • Zhou, X., Sun, H., Ellen, T. P., Chen, H., and Costa, M. (2008) Arsenite alters global histone H3 methylation. Carcinogenesis 29, 1831-1836
    • (2008) Carcinogenesis , vol.29 , pp. 1831-1836
    • Zhou, X.1    Sun, H.2    Ellen, T.P.3    Chen, H.4    Costa, M.5
  • 30
    • 0029416901 scopus 로고
    • The Polycomb and trithorax group proteins of Drosophila: Trans-regulators of homeotic gene function
    • Kennison, J. A. (1995) The Polycomb and trithorax group proteins of Drosophila: trans-regulators of homeotic gene function. Annu. Rev. Genet. 29, 289-303
    • (1995) Annu. Rev. Genet. , vol.29 , pp. 289-303
    • Kennison, J.A.1
  • 31
    • 57049141484 scopus 로고    scopus 로고
    • Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila
    • Oktaba, K., Gutiérrez, L., Gagneur, J., Girardot, C., Sengupta, A. K., Furlong, E. E., and Müller, J. (2008) Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila. Dev. Cell 15, 877-889
    • (2008) Dev. Cell , vol.15 , pp. 877-889
    • Oktaba, K.1    Gutiérrez, L.2    Gagneur, J.3    Girardot, C.4    Sengupta, A.K.5    Furlong, E.E.6    Müller, J.7
  • 32
    • 1642633053 scopus 로고    scopus 로고
    • Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
    • DOI 10.1038/nature02385
    • Leung, C., Lingbeek, M., Shakhova, O., Liu, J., Tanger, E., Saremaslani, P., Van Lohuizen, M., and Marino, S. (2004) Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas. Nature 428, 337-341 (Pubitemid 38418806)
    • (2004) Nature , vol.428 , Issue.6980 , pp. 337-341
    • Leung, C.1    Lingbeek, M.2    Shakhova, O.3    Liu, J.4    Tanger, E.5    Saremaslani, P.6    Van Lohuizen, M.7    Marino, S.8
  • 33
    • 33750379420 scopus 로고    scopus 로고
    • Polycomb silencers control cell fate, development and cancer
    • DOI 10.1038/nrc1991, PII NRC1991
    • Sparmann, A., and van Lohuizen, M. (2006) Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6, 846-856 (Pubitemid 44629896)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 846-856
    • Sparmann, A.1    Van Lohuizen, M.2
  • 35
    • 34248169728 scopus 로고    scopus 로고
    • The polycomb group protein Suz12 is required for embryonic stem cell differentiation
    • DOI 10.1128/MCB.01432-06
    • Pasini, D., Bracken, A. P., Hansen, J. B., Capillo, M., and Helin, K. (2007) The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol. Cell Biol. 27, 3769-3779 (Pubitemid 46726184)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.10 , pp. 3769-3779
    • Pasini, D.1    Bracken, A.P.2    Hansen, J.B.3    Capillo, M.4    Helin, K.5
  • 43
    • 33846148370 scopus 로고    scopus 로고
    • INK4a tumor suppressor gene
    • DOI 10.1101/gad.1499407
    • Kotake, Y., Cao, R., Viatour, P., Sage, J., Zhang, Y., and Xiong, Y. (2007) pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4- tumor suppressor gene. Genes Dev. 21, 49-54 (Pubitemid 46089706)
    • (2007) Genes and Development , vol.21 , Issue.1 , pp. 49-54
    • Kotake, Y.1    Cao, R.2    Viatour, P.3    Sage, J.4    Zhang, Y.5    Xiong, Y.6
  • 45
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycombgroup gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • DOI 10.1038/16476
    • Jacobs, J. J., Kieboom, K., Marino, S., DePinho, R. A., and van Lohuizen, M. (1999b) The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397, 164-168 (Pubitemid 29050921)
    • (1999) Nature , vol.397 , Issue.6715 , pp. 164-168
    • Jacobs, J.L.1    Kieboom, K.2    Marino, S.3    DePinho, R.A.4    Van Lohuizen, M.5
  • 46
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc- induced apoptosis via INK4a/ARF
    • DOI 10.1101/gad.13.20.2678
    • Jacobs, J. J., Scheijen, B., Voncken, J. W., Kieboom, K., Berns, A., and van Lohuizen, M. (1999a) Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev. 13, 2678-2690 (Pubitemid 29508555)
    • (1999) Genes and Development , vol.13 , Issue.20 , pp. 2678-2690
    • Jacobs, J.J.L.1    Scheijen, B.2    Voncken, J.-W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.