메뉴 건너뛰기




Volumn 24, Issue 2, 2005, Pages 117-125

Role of polycomb group proteins in stem cell self-renewal and cancer

Author keywords

[No Author keywords available]

Indexed keywords

EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; HISTONE; POLYCOMB GROUP PROTEIN; PROTEIN; PROTEIN BMI1; PROTEIN CBX2; PROTEIN CBX4; PROTEIN CBX6; PROTEIN CBX7; PROTEIN EDR2; PROTEIN EDR3; PROTEIN EZH1; PROTEIN EZH2; PROTEIN NSPC1; PROTEIN RAE28; PROTEIN RING1A; PROTEIN RING1B; PROTEIN RNF110; PROTEIN RNF134; PROTEIN RNF159; PROTEIN RNF3; PROTEIN SUZ12; UNCLASSIFIED DRUG;

EID: 13244279419     PISSN: 10445498     EISSN: None     Source Type: Journal    
DOI: 10.1089/dna.2005.24.117     Document Type: Review
Times cited : (144)

References (91)
  • 1
    • 0029809253 scopus 로고    scopus 로고
    • Structural organization of the r]ae28 gene, a putative murine homologue of the Drosophila polyhomeotic gene
    • Tokyo
    • ABDUL MOTALEB, M., TAKIHARA, Y., NOMURA, M., MATSUDA, Y., HIGASHINAKAGAWA, T., and SHIMADA, K. (1996). Structural organization of the rae28 gene, a putative murine homologue of the Drosophila polyhomeotic gene. J. Biochem. (Tokyo) 120, 797-802.
    • (1996) J. Biochem. , vol.120 , pp. 797-802
    • Abdul Motaleb, M.1    Takihara, Y.2    Nomura, M.3    Matsuda, Y.4    Higashinakagawa, T.5    Shimada, K.6
  • 2
    • 0029891279 scopus 로고    scopus 로고
    • A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton
    • AKASAKA, T., KANNO, M., BALLING, R., MIEZA, M.A., TANIGUCHI, M., and KOSEKI, H. (1996). A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. Development 122, 1513-1522.
    • (1996) Development , vol.122 , pp. 1513-1522
    • Akasaka, T.1    Kanno, M.2    Balling, R.3    Mieza, M.A.4    Taniguchi, M.5    Koseki, H.6
  • 3
    • 0034992693 scopus 로고    scopus 로고
    • Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression
    • AKASAKA, T., VAN LOHUIZEN, M., VAN DER LUGT, N., MIZUTANI-KOSEKI, Y., KANNO, M., TANIGUCHI, M., VIDAL, M., ALKEMA, M., BERNS, A., and KOSEKI, H. (2001). Mice doubly deficient for the Polycomb Group genes Mel18 and Bmi1 reveal synergy and requirement for maintenance but not initiation of Hox gene expression. Development 128, 1587-1597.
    • (2001) Development , vol.128 , pp. 1587-1597
    • Akasaka, T.1    Van Lohuizen, M.2    Van Der Lugt, N.3    Mizutani-Koseki, Y.4    Kanno, M.5    Taniguchi, M.6    Vidal, M.7    Alkema, M.8    Berns, A.9    Koseki, H.10
  • 4
    • 0030611381 scopus 로고    scopus 로고
    • Pertubation of B and T cell development and predisposition to lymphomagenesis in Emu Bmi1 transgenic mice require the Bmi1 RING finger
    • ALKEMA, M.J., JACOBS, H., VAN LOHUIZEN, M., and BERNS, A. (1997). Pertubation of B and T cell development and predisposition to lymphomagenesis in Emu Bmi1 transgenic mice require the Bmi1 RING finger. Oncogene 15, 899-910.
    • (1997) Oncogene , vol.15 , pp. 899-910
    • Alkema, M.J.1    Jacobs, H.2    Van Lohuizen, M.3    Berns, A.4
  • 7
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • BRACKEN, A.P., PASINI, D., CAPRA, M., PROSPERINI, E., COLLI, E., and HELIN, K. (2003). EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 22, 5323-5335.
    • (2003) EMBO J. , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 9
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • CAO, R., and ZHANG, Y. (2004). SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol. Cell 15, 57-67.
    • (2004) Mol. Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 10
    • 0031049215 scopus 로고    scopus 로고
    • Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice
    • CORE, N., BEL, S., GAUNT, S.J., AURRAND-LIONS, M., PEARCE, J., FISHER, A., and DJABALI, M. (1997). Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice. Development 124, 721-729.
    • (1997) Development , vol.124 , pp. 721-729
    • Core, N.1    Bel, S.2    Gaunt, S.J.3    Aurrand-Lions, M.4    Pearce, J.5    Fisher, A.6    Djabali, M.7
  • 11
    • 0037131523 scopus 로고    scopus 로고
    • Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites
    • CZERMIN, B., MELFI, R., MCCABE, D., SEITZ, V., IMHOF, A., and PIRROTTA, V. (2002). Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. Cell 111, 185-196.
    • (2002) Cell , vol.111 , pp. 185-196
    • Czermin, B.1    Melfi, R.2    Mccabe, D.3    Seitz, V.4    Imhof, A.5    Pirrotta, V.6
  • 17
    • 0031699524 scopus 로고    scopus 로고
    • The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo
    • FAUST, C., LAWSON, K.A., SCHORK, N.J., THIEL, B., and MAGNUSON, T. (1998). The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo. Development 125, 4495-4506.
    • (1998) Development , vol.125 , pp. 4495-4506
    • Faust, C.1    Lawson, K.A.2    Schork, N.J.3    Thiel, B.4    Magnuson, T.5
  • 19
    • 1342332096 scopus 로고    scopus 로고
    • Polycomb CBX7 has a unifying role in cellular lifespan
    • GIL, J., BERNARD, D., MARTINEZ, D., and BEACH, D. (2004). Polycomb CBX7 has a unifying role in cellular lifespan. Nat. Cell Biol. 6, 67-72.
    • (2004) Nat. Cell Biol. , vol.6 , pp. 67-72
    • Gil, J.1    Bernard, D.2    Martinez, D.3    Beach, D.4
  • 20
    • 0025727771 scopus 로고
    • Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in e mu-myc transgenic mice
    • HAUPT, Y., ALEXANDER, W.S., BARRI, G., KLINKEN, S.P., and ADAMS, J.M. (1991). Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice. Cell 65, 753-763.
    • (1991) Cell , vol.65 , pp. 753-763
    • Haupt, Y.1    Alexander, W.S.2    Barri, G.3    Klinken, S.P.4    Adams, J.M.5
  • 22
    • 0033552813 scopus 로고    scopus 로고
    • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
    • JACOBS, J.J., KIEBOOM, K., MARINO, S., DEPINHO, R.A., and VAN LOHUIZEN, M. (1999a). The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 397, 164-168.
    • (1999) Nature , vol.397 , pp. 164-168
    • Jacobs, J.J.1    Kieboom, K.2    Marino, S.3    Depinho, R.A.4    Van Lohuizen, M.5
  • 23
    • 0033569429 scopus 로고    scopus 로고
    • Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
    • JACOBS, J.J., SCHEIJEN, B., VONCKEN, J.W., KIEBOOM, K., BERNS, A., and VAN LOHUIZEN, M. (1999b). Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes Dev. 13, 2678-2690.
    • (1999) Genes Dev. , vol.13 , pp. 2678-2690
    • Jacobs, J.J.1    Scheijen, B.2    Voncken, J.W.3    Kieboom, K.4    Berns, A.5    Van Lohuizen, M.6
  • 24
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • JENUWEIN, T., and ALLIS, C.D. (2001). Translating the histone code. Science 293, 1074-1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 25
    • 2942618531 scopus 로고    scopus 로고
    • Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells
    • KAJIUME, T., NINOMIYA, Y., ISHIHARA, H., KANNO, R., and KANNO, M. (2004). Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells. Exp. Hematol. 32, 571-578.
    • (2004) Exp. Hematol. , vol.32 , pp. 571-578
    • Kajiume, T.1    Ninomiya, Y.2    Ishihara, H.3    Kanno, R.4    Kanno, M.5
  • 26
    • 0028840713 scopus 로고
    • mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity
    • KANNO, M., HASEGAWA, M., ISHIDA, A., ISONO, K., and TANIGUCHI, M. (1995). mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. EMBO J. 14, 5672-5678.
    • (1995) EMBO J. , vol.14 , pp. 5672-5678
    • Kanno, M.1    Hasegawa, M.2    Ishida, A.3    Isono, K.4    Taniguchi, M.5
  • 28
    • 3242759042 scopus 로고    scopus 로고
    • Defective long-term repopulating ability in hematopoietic stem cells lacking the Polycomb-group gene rae28
    • KIM, J.Y., SAWADA, A., TOKIMASA, S., ENDO, H., OZONO, K., HARA, J., and TAKIHARA, Y. (2004). Defective long-term repopulating ability in hematopoietic stem cells lacking the Polycomb-group gene rae28. Eur. J. Haematol. 73, 75-84.
    • (2004) Eur. J. Haematol. , vol.73 , pp. 75-84
    • Kim, J.Y.1    Sawada, A.2    Tokimasa, S.3    Endo, H.4    Ozono, K.5    Hara, J.6    Takihara, Y.7
  • 29
    • 0141576562 scopus 로고    scopus 로고
    • Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy
    • KIRMIZIS, A., BARTLEY, S.M., and FARNHAM, P.J. (2003). Identification of the polycomb group protein SU(Z)12 as a potential molecular target for human cancer therapy. Mol. Cancer Ther. 2, 113-121.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 113-121
    • Kirmizis, A.1    Bartley, S.M.2    Farnham, P.J.3
  • 32
    • 0142091482 scopus 로고    scopus 로고
    • Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF
    • KRANC, K.R., BAMFORTH, S.D., BRAGANCA, J., NORBURY, C., VAN LOHUIZEN, M., and BHATTACHARYA, S. (2003). Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF. Mol. Cell Biol. 23, 7658-7666.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 7658-7666
    • Kranc, K.R.1    Bamforth, S.D.2    Braganca, J.3    Norbury, C.4    Van Lohuizen, M.5    Bhattacharya, S.6
  • 33
    • 1942502862 scopus 로고    scopus 로고
    • Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3
    • KUZMICHEV, A., JENUWEIN, T., TEMPST, P., and REINBERG, D. (2004). Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol. Cell 14, 183-193.
    • (2004) Mol. Cell , vol.14 , pp. 183-193
    • Kuzmichev, A.1    Jenuwein, T.2    Tempst, P.3    Reinberg, D.4
  • 34
    • 0037111831 scopus 로고    scopus 로고
    • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
    • KUZMICHEV, A., NISHIOKA, K., ERDJUMENT-BROMAGE, H., TEMPST, P., and REINBERG, D. (2002). Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev. 16, 2893-2905.
    • (2002) Genes Dev. , vol.16 , pp. 2893-2905
    • Kuzmichev, A.1    Nishioka, K.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 35
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • LESSARD, J., and SAUVAGEAU, G. (2003). Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423, 255-260.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 36
    • 0032519809 scopus 로고    scopus 로고
    • Stage-specific expression of polycomb group genes in human bone marrow cells
    • LESSARD, J., BABAN, S., and SAUVAGEAU, G. (1998). Stage-specific expression of polycomb group genes in human bone marrow cells. Blood 91, 1216-1224.
    • (1998) Blood , vol.91 , pp. 1216-1224
    • Lessard, J.1    Baban, S.2    Sauvageau, G.3
  • 39
    • 0037309326 scopus 로고    scopus 로고
    • Tumor suppression by Ink4a-Arf: Progress and puzzles
    • LOWE, S.W., and SHERR, C.J. (2003). Tumor suppression by Ink4a-Arf: Progress and puzzles. Curr. Opin. Genet. Dev. 13, 77-83.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 77-83
    • Lowe, S.W.1    Sherr, C.J.2
  • 40
    • 2342475666 scopus 로고    scopus 로고
    • Polycomb complexes and silencing mechanisms
    • LUND, A.H., and VAN LOHUIZEN, M. (2004). Polycomb complexes and silencing mechanisms. Curr. Opin. Cell Biol. 16, 239-246.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 239-246
    • Lund, A.H.1    Van Lohuizen, M.2
  • 41
    • 0037381174 scopus 로고    scopus 로고
    • Genome imprinting regulated by the mouse Polycomb group protein Eed
    • MAGER, J., MONTGOMERY, N.D., DE VILLENA, F.P., and MAGNUSON, T. (2003). Genome imprinting regulated by the mouse Polycomb group protein Eed. Nat. Genet. 33, 502-507.
    • (2003) Nat. Genet. , vol.33 , pp. 502-507
    • Mager, J.1    Montgomery, N.D.2    De Villena, F.P.3    Magnuson, T.4
  • 43
    • 0041624288 scopus 로고    scopus 로고
    • Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
    • MIN, J., ZHANG, Y., and XU, R.M. (2003). Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes Dev. 17, 1823-1828.
    • (2003) Genes Dev. , vol.17 , pp. 1823-1828
    • Min, J.1    Zhang, Y.2    Xu, R.M.3
  • 44
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • MOLOFSKY, A.V., PARDAL, R., IWASHITA, T., PARK, I.K., CLARKE, M.F., and MORRISON, S.J. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962-967.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 45
    • 0344442774 scopus 로고    scopus 로고
    • Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA
    • MULHOLLAND, N.M., KING, I.F., and KINGSTON, R.E. (2003). Regulation of Polycomb group complexes by the sequence-specific DNA binding proteins Zeste and GAGA. Genes Dev. 17, 2741-2746.
    • (2003) Genes Dev. , vol.17 , pp. 2741-2746
    • Mulholland, N.M.1    King, I.F.2    Kingston, R.E.3
  • 48
    • 0037052539 scopus 로고    scopus 로고
    • A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in GO cells
    • OGAWA, H., ISHIGURO, K., GAUBATZ, S., LIVINGSTON, D.M., and NAKATANI, Y. (2002). A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in GO cells. Science 296, 1132-1136.
    • (2002) Science , vol.296 , pp. 1132-1136
    • Ogawa, H.1    Ishiguro, K.2    Gaubatz, S.3    Livingston, D.M.4    Nakatani, Y.5
  • 50
    • 0141785202 scopus 로고    scopus 로고
    • Gene repression by Polycomb group protein complexes: A distinct complex for every occasion?
    • OTTE, A.P., and KWAKS, T.H. (2003). Gene repression by Polycomb group protein complexes: A distinct complex for every occasion? Curr. Opin. Genet. Dev. 13, 448-454.
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 448-454
    • Otte, A.P.1    Kwaks, T.H.2
  • 52
    • 3042702970 scopus 로고    scopus 로고
    • Polycomb group proteins in cell cycle progression and cancer
    • PASINI, D., BRACKEN, A.P., and HELIN, K. (2004). Polycomb group proteins in cell cycle progression and cancer. Cell Cycle 3, 396-400.
    • (2004) Cell Cycle , vol.3 , pp. 396-400
    • Pasini, D.1    Bracken, A.P.2    Helin, K.3
  • 53
    • 0035476530 scopus 로고    scopus 로고
    • Establishment of Polycomb silencing requires a transient interaction between PC and ESC
    • POUX, S., MELFI, R., and PIRROTTA, V. (2001). Establishment of Polycomb silencing requires a transient interaction between PC and ESC. Genes Dev. 15, 2509-2514.
    • (2001) Genes Dev. , vol.15 , pp. 2509-2514
    • Poux, S.1    Melfi, R.2    Pirrotta, V.3
  • 55
    • 13244296425 scopus 로고    scopus 로고
    • Correspondence re: S. Bea et al., BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas
    • RAAPHORST, F.M., MEIJER, C.J., and OTTE, A.P. (2002). Correspondence re: S. Bea et al., BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. Cancer Res. 61, 2409-2412, 2001. Cancer Res 62, 618-619.
    • (2002) Cancer Res. , vol.61 , pp. 2409-2412
    • Raaphorst, F.M.1    Meijer, C.J.2    Otte, A.P.3
  • 56
    • 13244274434 scopus 로고    scopus 로고
    • RAAPHORST, F.M., MEIJER, C.J., and OTTE, A.P. (2002). Correspondence re: S. Bea et al., BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. Cancer Res. 61, 2409-2412, 2001. Cancer Res 62, 618-619.
    • Cancer Res , vol.62 , pp. 618-619
  • 58
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • REYA, T., MORRISON, S.J., CLARKE, M.F., and WEISSMAN, I.L. (2001). Stem cells, cancer, and cancer stem cells. Nature 414, 105-111.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 59
    • 0037846472 scopus 로고    scopus 로고
    • Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer
    • RHODES, D.R., SANDA, M.G., OTTE, A.P., CHINNAIYAN, A.M., and RUBIN, M.A. (2003). Multiplex biomarker approach for determining risk of prostate-specific antigen-defined recurrence of prostate cancer. J. Natl. Cancer Inst. 95, 661-668.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 661-668
    • Rhodes, D.R.1    Sanda, M.G.2    Otte, A.P.3    Chinnaiyan, A.M.4    Rubin, M.A.5
  • 60
    • 0027428234 scopus 로고
    • N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7
    • RINCHIK, E.M., and CARPENTER, D.A. (1993). N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7. Mamm. Genome 4, 349-353.
    • (1993) Mamm. Genome , vol.4 , pp. 349-353
    • Rinchik, E.M.1    Carpenter, D.A.2
  • 61
    • 0242362735 scopus 로고    scopus 로고
    • Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster
    • RINGROSE, L., REHMSMEIER, M., DURA, J.M., and PARO, R. (2003). Genome-wide prediction of Polycomb/Trithorax response elements in Drosophila melanogaster. Dev. Cell 5, 759-771.
    • (2003) Dev. Cell , vol.5 , pp. 759-771
    • Ringrose, L.1    Rehmsmeier, M.2    Dura, J.M.3    Paro, R.4
  • 62
    • 0032927872 scopus 로고    scopus 로고
    • RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity
    • SATIJN, D.P., and OTTE, A.P. (1999). RING1 interacts with multiple Polycomb-group proteins and displays tumorigenic activity. Mol. Cell Biol. 19, 57-68.
    • (1999) Mol. Cell Biol. , vol.19 , pp. 57-68
    • Satijn, D.P.1    Otte, A.P.2
  • 64
    • 0035144663 scopus 로고    scopus 로고
    • The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos
    • SATIJN, D.P., HAMER, K.M., DEN BLAAUWEN, J., and OTTE, A.P. (2001). The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos. Mol. Cell Biol. 21, 1360-1369.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 1360-1369
    • Satijn, D.P.1    Hamer, K.M.2    Den Blaauwen, J.3    Otte, A.P.4
  • 65
    • 1842364897 scopus 로고    scopus 로고
    • Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain
    • SCHOORLEMMER, J., MARCOS-GUTIERREZ, C., WERE, F., MARTINEZ, R., GARCIA, E., SATIJN, D.P., OTTE, A.P., and VIDAL, M. (1997). Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain. EMBO J. 16, 5930-5942.
    • (1997) EMBO J. , vol.16 , pp. 5930-5942
    • Schoorlemmer, J.1    Marcos-Gutierrez, C.2    Were, F.3    Martinez, R.4    Garcia, E.5    Satijn, D.P.6    Otte, A.P.7    Vidal, M.8
  • 66
    • 0031842310 scopus 로고    scopus 로고
    • Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes
    • SEWALT, R.G., VAN DER VLAG, J., GUNSTER, M.J., HAMER, K.M., DEN BLAAUWEN, J.L., SATIJN, D.P., HENDRIX, T., VAN DRIEL, R., and OTTE, A.P. (1998). Characterization of interactions between the mammalian polycomb-group proteins Enx1/EZH2 and EED suggests the existence of different mammalian polycomb-group protein complexes. Mol. Cell Biol. 18, 3586-3595.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3586-3595
    • Sewalt, R.G.1    Van Der Vlag, J.2    Gunster, M.J.3    Hamer, K.M.4    Den Blaauwen, J.L.5    Satijn, D.P.6    Hendrix, T.7    Van Driel, R.8    Otte, A.P.9
  • 67
    • 0036310641 scopus 로고    scopus 로고
    • Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins
    • SEWALT, R.G., LACHNER, M., VARGAS, M., HAMER, K.M., DEN BLAAUWEN, J.L., HENDRIX, T., MELCHER, M., SCHWEIZER, D., JENUWEIN, T., and OTTE, A.P. (2002). Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins. Mol. Cell Biol. 22, 5539-5553.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 5539-5553
    • Sewalt, R.G.1    Lachner, M.2    Vargas, M.3    Hamer, K.M.4    Den Blaauwen, J.L.5    Hendrix, T.6    Melcher, M.7    Schweizer, D.8    Jenuwein, T.9    Otte, A.P.10
  • 68
    • 0033037541 scopus 로고    scopus 로고
    • The INK4A/ARF locus and its two gene products
    • SHARPLESS, N.E., and DEPINHO, R.A. (1999). The INK4A/ARF locus and its two gene products. Curr. Opin. Genet. Dev. 9, 22-30.
    • (1999) Curr. Opin. Genet. Dev. , vol.9 , pp. 22-30
    • Sharpless, N.E.1    Depinho, R.A.2
  • 69
    • 85047689866 scopus 로고    scopus 로고
    • Telomeres, stem cells, senescence, and cancer
    • SHARPLESS, N.E., and DEPINHO, R.A. (2004). Telomeres, stem cells, senescence, and cancer. J. Clin. Invest. 113, 160-168.
    • (2004) J. Clin. Invest. , vol.113 , pp. 160-168
    • Sharpless, N.E.1    Depinho, R.A.2
  • 70
    • 0035487104 scopus 로고    scopus 로고
    • The INK4a/ARF network in tumor suppression
    • SHERR, C.J. (2001). The INK4a/ARF network in tumor suppression. Nat. Rev. Mol. Cell Biol. 2, 731-737.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 731-737
    • Sherr, C.J.1
  • 71
    • 0037387711 scopus 로고    scopus 로고
    • Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes
    • SILVA, J., MAK, W., ZVETKOVA, I., APPANAH, R., NESTEROVA, T.B., WEBSTER, Z., PETERS, A.H., JENUWEIN, T., OTTE, A.P., and BROCKDORFF, N. (2003). Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev. Cell 4, 481-495.
    • (2003) Dev. Cell , vol.4 , pp. 481-495
    • Silva, J.1    Mak, W.2    Zvetkova, I.3    Appanah, R.4    Nesterova, T.B.5    Webster, Z.6    Peters, A.H.7    Jenuwein, T.8    Otte, A.P.9    Brockdorff, N.10
  • 72
    • 0042643562 scopus 로고    scopus 로고
    • Polycomb group proteins
    • SIMON, J.A. (2003). Polycomb group proteins. Curr. Biol. 13, R79-R80.
    • (2003) Curr. Biol. , vol.13
    • Simon, J.A.1
  • 73
    • 0141922983 scopus 로고    scopus 로고
    • Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1
    • SMITH, K.S., CHANDA, S.K., LINGBEEK, M., ROSS, D.T., BOTSTEIN, D., VAN LOHUIZEN, M., and CLEARY, M.L. (2003). Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Mol. Cell 12, 393-400.
    • (2003) Mol. Cell , vol.12 , pp. 393-400
    • Smith, K.S.1    Chanda, S.K.2    Lingbeek, M.3    Ross, D.T.4    Botstein, D.5    Van Lohuizen, M.6    Cleary, M.L.7
  • 75
    • 0030729636 scopus 로고    scopus 로고
    • Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects
    • TAKIHARA, Y., TOMOTSUNE, D., SHIRAI, M., KATOH-FUKUI, Y., NISHII, K., MOTALEB, M.A., NOMURA, M., TSUCHIYA, R., FUJITA, Y., SHIBATA, Y., et al. (1997). Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects. Development 124, 3673-3682.
    • (1997) Development , vol.124 , pp. 3673-3682
    • Takihara, Y.1    Tomotsune, D.2    Shirai, M.3    Katoh-Fukui, Y.4    Nishii, K.5    Motaleb, M.A.6    Nomura, M.7    Tsuchiya, R.8    Fujita, Y.9    Shibata, Y.10
  • 76
    • 0032191954 scopus 로고    scopus 로고
    • mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25
    • TETSU, O., ISHIHARA, H., KANNO, R., KAMIYASU, M., INOUE, H., TOKUHISA, T., TANIGUCHI, M., and KANNO, M. (1998). mel-18 negatively regulates cell cycle progression upon B cell antigen receptor stimulation through a cascade leading to c-myc/cdc25. Immunity 9, 439-448.
    • (1998) Immunity , vol.9 , pp. 439-448
    • Tetsu, O.1    Ishihara, H.2    Kanno, R.3    Kamiyasu, M.4    Inoue, H.5    Tokuhisa, T.6    Taniguchi, M.7    Kanno, M.8
  • 77
    • 0035172279 scopus 로고    scopus 로고
    • Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell developmental stage
    • TOKIMASA, S., OHTA, H., SAWADA, A., MATSUDA, Y., KIM, J.Y., NISHIGUCHI, S., HARA, J., and TAKIHARA, Y. (2001). Lack of the Polycomb-group gene rae28 causes maturation arrest at the early B-cell developmental stage. Exp. Hematol. 29, 93-103.
    • (2001) Exp. Hematol. , vol.29 , pp. 93-103
    • Tokimasa, S.1    Ohta, H.2    Sawada, A.3    Matsuda, Y.4    Kim, J.Y.5    Nishiguchi, S.6    Hara, J.7    Takihara, Y.8
  • 78
    • 0033396834 scopus 로고    scopus 로고
    • A novel member of murine Polycomb-group proteins, sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro
    • TOMOTSUNE, D., TAKIHARA, Y., BERGER, J., DUHL, D., JOO, S., KYBA, M., SHIRAI, M., OHTA, H., MATSUDA, Y., HONDA, B.M., et al. (1999). A novel member of murine Polycomb-group proteins, sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro. Differentiation 65, 229-239.
    • (1999) Differentiation , vol.65 , pp. 229-239
    • Tomotsune, D.1    Takihara, Y.2    Berger, J.3    Duhl, D.4    Joo, S.5    Kyba, M.6    Shirai, M.7    Ohta, H.8    Matsuda, Y.9    Honda, B.M.10
  • 79
    • 0035852632 scopus 로고    scopus 로고
    • The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
    • TRIMARCHI, J.M., FAIRCHILD, B., WEN, J., and LEES, J.A. (2001). The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA 98, 1519-1524.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1519-1524
    • Trimarchi, J.M.1    Fairchild, B.2    Wen, J.3    Lees, J.A.4
  • 81
    • 0032751323 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
    • VAN DER VLAG, J., and OTTE, A.P. (1999). Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat. Genet. 23, 474-478.
    • (1999) Nat. Genet. , vol.23 , pp. 474-478
    • Van Der Vlag, J.1    Otte, A.P.2
  • 82
    • 0035877978 scopus 로고    scopus 로고
    • Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma
    • VAN KEMENADE, F.J., RAAPHORST, F.M., BLOKZIJL, T., FIERET, E., HAMER, K.M., SATIJN, D.P., OTTE, A.P., and MEIJER, C.J. (2001). Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma. Blood 97, 3896-3901.
    • (2001) Blood , vol.97 , pp. 3896-3901
    • Van Kemenade, F.J.1    Raaphorst, F.M.2    Blokzijl, T.3    Fieret, E.4    Hamer, K.M.5    Satijn, D.P.6    Otte, A.P.7    Meijer, C.J.8
  • 83
    • 0025863346 scopus 로고
    • Identification of cooperating oncogenes in e mu-myc transgenic mice by provirus tagging
    • VAN LOHUIZEN, M., VERBEEK, S., SCHEIJEN, B., WIENTJENS, E., VAN DER GULDEN, H., and BERNS, A. (1991). Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 65, 737-752.
    • (1991) Cell , vol.65 , pp. 737-752
    • Van Lohuizen, M.1    Verbeek, S.2    Scheijen, B.3    Wientjens, E.4    Van Der Gulden, H.5    Berns, A.6
  • 84
    • 0031843056 scopus 로고    scopus 로고
    • Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: Indication for separate Pc-G complexes
    • VAN LOHUIZEN, M., TIJMS, M., VONCKEN, J.W., SCHUMACHER, A., MAGNUSON, T., and WIENTJENS, E. (1998). Interaction of mouse polycomb-group (Pc-G) proteins Enx1 and Enx2 with Eed: Indication for separate Pc-G complexes. Mol. Cell Biol. 18, 3572-3579.
    • (1998) Mol. Cell Biol. , vol.18 , pp. 3572-3579
    • Van Lohuizen, M.1    Tijms, M.2    Voncken, J.W.3    Schumacher, A.4    Magnuson, T.5    Wientjens, E.6
  • 89
    • 0036707815 scopus 로고    scopus 로고
    • The mouse PcG gene eed is required for Hox gene repression and extraembryonic development
    • WANG, J., MAGER, J., SCHNEDIER, E., and MAGNUSON, T. (2002). The mouse PcG gene eed is required for Hox gene repression and extraembryonic development. Mamm Genome 13, 493-503.
    • (2002) Mamm. Genome , vol.13 , pp. 493-503
    • Wang, J.1    Mager, J.2    Schnedier, E.3    Magnuson, T.4
  • 90
    • 0034802618 scopus 로고    scopus 로고
    • Use of chromatin immunoprecipitation to clone novel E2F target promoters
    • WEINMANN, A.S., BARTLEY, S.M., ZHANG, T., ZHANG, M.Q., and FARNHAM, P.J. (2001). Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol. Cell Biol. 21, 6820-6832.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 6820-6832
    • Weinmann, A.S.1    Bartley, S.M.2    Zhang, T.3    Zhang, M.Q.4    Farnham, P.J.5
  • 91
    • 0347683447 scopus 로고    scopus 로고
    • Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2
    • YAMAMOTO, K., SONODA, M., INOKUCHI, J., SHIRASAWA, S., and SASAZUKI, T. (2004). Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 2. J. Biol. Chem. 279, 401-406.
    • (2004) J. Biol. Chem. , vol.279 , pp. 401-406
    • Yamamoto, K.1    Sonoda, M.2    Inokuchi, J.3    Shirasawa, S.4    Sasazuki, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.