Comparison of sensitivity to arsenic compounds between a Bhas 42 cell transformation assay and a BALB/c 3T3 cell transformation assay

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 675, Issue 1-2, 2009, Pages 66-70

  Muramatsu, Dai ^a   Sasaki, Kiyoshi ^a   Kuroda, Sachiko ^a   Hayashi, Kumiko ^a   Tanaka, Noriho ^a   Sakai, Ayako ^a  

^a HATANO RESEARCH INSTITUTE   (Japan)

Author keywords

Arsenic; BALB c 3T3 cells; Bhas 42 cells; Cell transformation; Initiation and promotion; v Ha ras

Indexed keywords

3 METHYLCHOLANTHRENE; ARSENATE SODIUM; ARSENIC DERIVATIVE; ARSENITE SODIUM; CACODYLIC ACID; METHANEARSONIC ACID;

ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL TRANSFORMATION; CHEMICAL CARCINOGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

ANIMALS; ARSENATES; ARSENICALS; ARSENITES; BALB 3T3 CELLS; CACODYLIC ACID; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE;

MAMMALIA;

EID: 64549122358     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2009.02.008     Document Type: Article

References (24)

1. Kuroki T., and Sasaki K. Relationship between in vitro cell transformation and in vivo carcinogenesis based on available data on the effects of chemicals. In: Kakunaga T., and Yamasaki H. (Eds). Transformation Assay of Established Cell Lines: Mechanisms and Application. IARC Scientific Publication No. 67 (1985), IARC, Lyon 93-118
2. Barrett J.C., Kakunaga T., Kuroki T., Neubert D., Trosko J.E., Vasiliev J.M., Williams G.M., and Yamasaki H. Mammalian cell transformation in culture. In: Montesano R., Bartsch H., Vainio H., Wilbourn J., and Yamasaki H. (Eds). Long-Term and Short-Term Assays for Carcinogens: A Critical Appraisal. IARC Scientific Publication No. 83 (1986), IARC, Lyon 267-286
3. Nagalakshmi K. Tumorigenicity of morphologically distinct transformed foci induced by 3-methylcholanthrene in BALB/c-3T3 cells. Mutat. Res. 447 (2000) 281-286
4. Mondal S., Brankow D.W., and Heidelberger C. Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells. Cancer Res. 36 (1976) 2254-2260
5. Hirakawa T., Kakunaga T., Fujiki H., and Sugimura T. A new tumor-promoting agent, dihydroteleocidin B, markedly enhances chemically induced malignant cell transformation. Science 216 (1982) 527-529
6. Mondal S., and Heidelberger C. Transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by ultraviolet irradiation and a phorbol ester. Nature 260 (1976) 710-711
7. Katoh F., Fitzgerald D.J., Giroldi L., Fujiki H., Sugimura T., and Yamasaki H. Okadaic acid and phorbol esters: comparative effects of these tumor promoters on cell transformation, intercellular communication and differentiation in vitro. Jpn. J. Cancer Res. 81 (1990) 590-597
8. Sakai A., and Fujiki H. Promotion of BALB/3T3 cell transformation by the okadaic acid class of tumor promoters, okadaic acid and dinophysistoxin-1. Jpn. J. Cancer Res. 82 (1991) 518-523
9. Sakai A., Iwase Y., Nakamura Y., Sasaki K., Tanaka N., and Umeda M. Use of a cell transformation assay with established cell lines, and a metabolic cooperation assay with V79 cells for the detection of tumor promoters: a review. ATLA 30 (2002) 33-59
10. Sakai A., and Sato M. Improvement of carcinogen identification in BALB/3T3 cell transformation by application of a 2-stage method. Mutat. Res. 214 (1989) 285-296
11. Kakunaga T. A quantitative system for assay of malignant transformation by chemical carcinogens using a clone derived from BALB/3T3. Int. J. Cancer 12 (1973) 463-473
12. Kakunaga T., and Crow J.D. Cell variants showing differential susceptibility to ultraviolet light-induced transformation. Science 209 (1980) 505-507
13. Sakai A. BALB/c 3T3 cell transformation assays for the assessment of chemical carcinogenicity. AATEX 13 Special Issue (2008) 367-373
14. Sasaki K., Mizusawa H., and Ishidate M. Isolation and characterization of ras-transfected BALB/3T3 clone showing morphological transformation by 12-O-tetradecanoyl-phorbol-13-acetate. Jpn. J. Cancer Res. 79 (1988) 921-930
15. Sasaki K., Mizusawa H., Ishidate M., and Tanaka N. Establishment of a highly reproducible transformation assay of a ras-transfected BALB 3T3 clone by treatment with promoters. Basic Life Sci. 52 (1990) 411-416
16. Ohmori K., Sasaki K., Asada S., Tanaka N., and Umeda M. An assay method for the prediction of tumor promoting potential of chemicals by the use of Bhas 42 cells. Mutat. Res. 557 (2004) 191-202
17. Asada S., Sasaki K., Tanaka N., Takeda K., Hayashi M., and Umeda M. Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c 3T3 cells (Bhas 42 cells). Mutat. Res. 588 (2005) 7-21
18. Rossman T.G. Mechanism of arsenic carcinogenesis: an integrated approach. Mutat. Res. 533 (2003) 37-65
19. IARC. Arsenic in drinking-water. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol. 82. Some Drinking-water Disinfectants and Contaminants. Including Arsenic (2004), IARC, Lyon pp. 39-267
20. Lee T.-C., Oshimura M., and Barrett J.C. Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture. Carcinogenesis 6 (1985) 1421-1436
21. Bertolero F., Pozzi G., Sabbioni E., and Saffiotti U. Cellular uptake and metabolic reduction of pentavalent to trivalent arsenic as determinants of cytotoxicity and morphological transformation. Carcinogenesis 8 (1987) 803-808
22. Zhao C.Q., Young M.R., Diwan B.A., Coogan T.P., and Waalkes M.P. Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 10907-10912
23. Tsuchiya T., Tanaka-Kagawa T., Jinno H., Tokunaga H., Sakimoto K., Ando M., and Umeda M. Inorganic arsenic compounds and methylated metabolites induce morphological transformation in two-stage BALB/c 3T3 cell assay and inhibit metabolic cooperation in V79 cell assay. Toxicol. Sci. 84 (2005) 344-351
24. IARC/NCI/EPA Working Group. Cellular and molecular mechanisms of cell transformation and standardization of transformation assays of established cell lines for the prediction of carcinogenic chemicals: overview and recommended protocols. Cancer Res. 44 (1985) 2395-2399