Crystal structure and functional analysis of the histone methyltransferase SET7/9

Cell

Volumn 111, Issue 1, 2002, Pages 105-115

  Wilson, Jonathan R ^a   Jing, Chun ^a   Walker, Philip A ^a   Martin, Stephen R ^a   Howell, Steven A ^a   Blackburn, G Michael ^b   Gamblin, Steven J ^a   Xiao, Bing ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; LYSINE; METHYLTRANSFERASE; PEPTIDE; PROTEIN SET7 9; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BIOCHEMISTRY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ANALYSIS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION;

EID: 0037020032     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00964-9     Document Type: Article

References (35)

1. Bannister A.J., Zegerman P., Partridge J.F., Miska E.A., Thomas J.O., Allshire R.C., Kouzarides T. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature. 410:2001;120-124.
2. CCP4 The CCP4 (Collaborative Computational Project 4) suite. programs for protein crystallography Acta Crystallogr. D. 50:1994;760-763.
3. Cheng X., Roberts R.J. AdoMet-dependent methylation, DNA methyltransferases and base flipping. Nucleic Acids Res. 29:2001;3784-3795.
4. Dillon N., Festenstein R. Unravelling heterochromatin. competition between positive and negative factors regulates accessibility Trends Genet. 18:2002;252-258.
5. Dinner A.R., Blackburn G.M., Karplus M. Uracil-DNA glycosylase acts by substrate autocatalysis. Nature. 413:2001;752-755.
6. Eissenberg J.C., Elgin S.C. The HP1 protein family. getting a grip on chromatin Curr. Opin. Genet. Dev. 10:2000;204-210.
7. Grunstein M. Histone acetylation in chromatin structure and transcription. Nature. 389:1997;349-352.
8. Hoffmann J.L. Chromatographic analysis of the chiral and covalent instability of S-adenosyl-L-methionine. Biochemistry. 25:1986;4444-4449.
9. Jones R.S., Gelbart W.M. The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax. Mol. Cell. Biol. 13:1993;6357-6366.
10. Lachner M., Jenuwein T. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14:2002;286-298.
11. Lachner M., O'Carroll D., Rea S., Mechtler K., Jenuwein T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature. 410:2001;116-120.
12. Litt M.D., Simpson M., Gaszner M., Allis C.D., Felsenfeld G. Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus. Science. 293:2001;2453-2455.
13. Luger K., Mader A.W., Richmond R.K., Sargent D.F., Richmond T.J. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature. 389:1997;251-260.
14. Masino L., Martin S.R., Bayley P.M. Ligand binding and thermodynamic stability of a multidomain protein, calmodulin. Protein Sci. 9:2000;1519-1529.
15. Murray K. The occurrence of ε-N-methyl lysine in histones. Biochemistry. 3:1964;10-15.
16. Nakayama J., Rice J.C., Strahl B.D., Allis C.D., Grewal S.I. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science. 292:2001;110-113.
17. Nishioka K., Chuikov S., Sarma K., Erdjument-Bromage H., Allis C.D., Tempst P., Reinberg D. Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev. 16:2002;479-489. a.
18. Nishioka K., Rice J.C., Sarma K., Erdjument-Bromage H., Werner J., Wang Y., Chuikov S., Valenzuela P., Tempst P., Steward R.et al. PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. Mol. Cell. 9:2002;1201-1213. b.
19. Noma K., Allis C.D., Grewal S.I. Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries. Science. 293:2001;1150-1155.
20. Otwinowski Z.M., Minor W. Processing of x-ray diffraction data collected in oscillation mode. Carter C.W. Jr., Sweet R.M. Methods in Enzymology, Volume 276. 1997;Academic Press, New York. 307-325.pp.
21. Rafferty J.B., Somers W.S., Saint-Girons I., Phillips S.E. Three-dimensional crystal structure of Escherichia coli met repressor with and without corepressor. Nature. 341:1989;705-710.
22. Rea S., Eisenhaber F., O'Carroll D., Strahl B.D., Sun Z.W., Schmid M., Opravil S., Mechtler K., Ponting C.P., Allis C.D., Jenuwein T. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature. 406:2000;593-599.
23. Roguev A., Schaft D., Shevchenko A., Pijnappel W.W., Wilm M., Aasland R., Stewart A.F. The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4. EMBO J. 20:2001;7137-7148.
24. Spellman P.T., Rubin G.M. Evidence for large domains of similarly expressed genes in the Drosophila genome. J. Biol. 1:2002;1-8.
25. Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature. 403:2000;41-45.
26. Takusagawa, F., Fujioka, M., Spies, A., and Schowen, R.L. (1998). S-Adenosyl Methionine Dependent Methyltransferases, Volume 1 (London: Academic Press).
27. Terwilliger T.C., Berendzen J. Automated MAD and MIR structure solution. Acta Crystallogr. D. 55:1999;849-861.
28. Thompson M.J., Mekhalfia A., Hornby D.P., Blackburn G.M. Synthesis of two stable nitrogen analogues of S-adenosyl-L-methionine. J. Org. Chem. 64:1999;7467-7473.
29. Tschiersch B., Hofmann A., Krauss V., Dorn R., Korge G., Reuter G. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13:1994;3822-3831.
30. Turner B.M. Histone acetylation and an epigenetic code. Bioessays. 22:2000;836-845.
31. Wang H., Cao R., Xia L., Erdjument-Bromage H., Borchers C., Tempst P., Zhang Y. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol. Cell. 8:2001;1207-1217.
32. Winn M.D., Isupov M.N., Murshudov G.N. Use of TLS parameters to model anisotropic displacements in macromolecular refinement. Acta Crystallogr. D Biol. Crystallogr. 57:2001;122-133.
33. Wolffe A.P. Chromatin. Structure and Function:1998;Academic Press, San Diego.
34. Zegerman P., Canas B., Pappin D., Kouzarides T. Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J. Biol. Chem. 277:2002;11621-11624.
35. Zhang Y., Reinberg D. Transcription regulation by histone methylation. interplay between different covalent modifications of the core histone tails Genes Dev. 15:2001;2343-2360.