Severe acute respiratory syndrome coronavirus replication is severely impaired by MG132 due to proteasome-independent inhibition of M-calpain

Journal of Virology

Volumn 86, Issue 18, 2012, Pages 10112-10122

  Schneider, Martha ^a,b   Ackermann, Kerstin ^a   Stuart, Melissa ^c   Wex, Claudia ^a   Protzer, Ulrike ^a,b   Schätzl, Hermann M ^a,c   Gilch, Sabine ^a,c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF WYOMING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALPAIN 2;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; AUTOPHAGY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; SARS CORONAVIRUS; SIGNAL TRANSDUCTION; VIRUS ENTRY; VIRUS REPLICATION; WILD TYPE;

ANIMALS; AUTOPHAGY; BASE SEQUENCE; CALPAIN; CELL LINE; CERCOPITHECUS AETHIOPS; CYSTEINE PROTEINASE INHIBITORS; GENE KNOCKDOWN TECHNIQUES; HUMANS; LEUPEPTINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; RNA, SMALL INTERFERING; SARS VIRUS; VERO CELLS; VIRUS INTERNALIZATION; VIRUS REPLICATION;

MURINE HEPATITIS VIRUS; SARS CORONAVIRUS;

EID: 84866146375     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01001-12     Document Type: Article

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