Ubiquitination is essential for human cytomegalovirus US11-mediated dislocation of MHC class I molecules from the endoplasmic reticulum to the cytosol

Biochemical Journal

Volumn 358, Issue 2, 2001, Pages 369-377

  Kikkert, M ^a   Hasslnk, G M ^a   Barel Christian, H ^a   Van der Wal, F J ^a   Wiertz, E ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Degradation; E1 enzyme; Proteasome; Retrotranslocation; Ubiquitin

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; DEGRADATION; MOLECULES; MUTAGENESIS; THERMAL EFFECTS; TOPOLOGY;

HUMAN CYTOMEGALOVIRUS;

BIOCHEMISTRY;

GLUCAN SYNTHASE; MAJOR HISTOCOMPATIBILITY ANTIGEN; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOSOL; DEGLYCOSYLATION; ENDOPLASMIC RETICULUM; MAJOR HISTOCOMPATIBILITY COMPLEX; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; TEMPERATURE DEPENDENCE;

ANIMALS; CELL LINE; CRICETINAE; CYSTEINE ENDOPEPTIDASES; CYTOSOL; ENDOPLASMIC RETICULUM; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-A2 ANTIGEN; INTRACELLULAR MEMBRANES; LIGASES; MULTIENZYME COMPLEXES; MUTATION; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; RNA-BINDING PROTEINS; SULFONES; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; VIRAL ENVELOPE PROTEINS; VIRAL PROTEINS;

EID: 0035448296     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3580369     Document Type: Article

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