Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

Journal of Biological Chemistry

Volumn 278, Issue 40, 2003, Pages 38980-38990

  Li, Dongtao Ni ^a   Matthews, Stephen P ^a   Antoniou, Antony N ^a   Mazzeo, Daniela ^a   Watts, Colin ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELL CULTURE; ENZYMES; PH EFFECTS;

PRECURSORS;

BIOCHEMISTRY;

AMINO ACID; ASPARAGINE; ASPARTIC ACID; CYSTEINE PROTEINASE; LEGUMAIN; LIPOPOLYSACCHARIDE; LYSOSOME ENZYME; PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MATURATION; DENDRITIC CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PURIFICATION; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; ANIMALS; ASPARAGINE; ASPARTIC ACID; CELL LINE; CELLS, CULTURED; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CYSTEINE ENDOPEPTIDASES; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOPOLYSACCHARIDES; LYSOSOMES; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MONOCYTES; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDES; PLANT PROTEINS; PROTEIN STRUCTURE, TERTIARY; RABBITS; SHEEP; TIME FACTORS; TRANSFECTION;

MAMMALIA;

EID: 0141755165     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305930200     Document Type: Article

References (56)

1. Chen, J. M., Dando, P. M., Rawlings, N. D., Brown, M. A., Young, N. E., Stevens, R. A., Hewitt, E., Watts, C., and Barrett, A. J. (1997) J. Biol. Chem. 272, 8090-8098
2. Turk, B., Turk, D., and Turk, V. (2000) Biochim. Biophys. Acta 1477, 98-111
3. Shutov, A. D., Do, N. L., and Vaintraub, I. A. (1982) Biokhimiia 47, 814-821
4. Hara-Nishimura, I., Takeuchi, Y., and Nishimura, M. (1993) Plant Cell 5, 1651-1659
5. Kembhavi, A. A., Buttle, D. J., Knight, C. G., and Barrett, A. J. (1993) Arch. Biochem. Biophys. 303, 208-213
6. Klinkert, M. Q., Felleisen, R., Link, G., Ruppel, A., and Beck, E. (1989) Mol. Biochem. Parasitol. 33, 113-122
7. Dalton, J. P., Hola Jamriska, L., and Brindley, P. J. (1995) Parasitology 111, 575-580
8. Uhlmann, F., Wernic, D., Poupart, M. A., Koonin, E. V., and Nasmyth, K. (2000) Cell 103, 375-386
9. Chen, J. M., Rawlings, N. D., Stevens, R. A. E., and Barrett, A. J. (1998) FEBS Lett. 441, 461-365
10. Manoury, B., Hewitt, E. W., Morrice, N., Dando, P. M., Barrett, A. J., and Watts, C. (1998) Nature 396, 695-699
11. Antoniou, A. N., Blackwood, S. L., Mazzeo, D., and Watts, C. (2000) Immunity 12, 391-398
12. Manoury, B., Mazzeo, D., Fugger, L., Viner, N., Ponsford, M., Streeter, H., Mazza, G., Wraith, D. C., and Watts, C. (2002) Nat. Immunol. 3, 169-174
13. Anderton, S. M., Viner, N. J., Matharu, P., Lowrey, P. A., and Wraith, D. C. (2002) Nat. Immunol. 3, 110-112
14. Beck, H., Schwarz, G., Schroter, C. J., Deeg, M., Baier, D., Stevanovic, S., Weber, E., Driessen, C., and Kalbacher, H. (2001) Eur. J. Immunol. 31, 3726-3736
15. Lennon-Dumenil, A. M., Bakker, A. H., Wolf-Bryant, P., Ploegh, H. L., and Lagaudriere-Gesbert, C. (2002) Curr. Opin. Immunol. 14, 15-21
16. Manoury, B., Mazzeo, D., Li, D. N., Billson, J., Loak, K., Benaroch, P., and Watts, C (2003) Immunity 18, 489-498
17. Chen, J. M., Fortunato, M., Stevens, R. A., and Barrett, A. J. (2001) Biol. Chem. 382, 777-783
18. Sarandeses, C. S., Covelo, G., Diaz-Jullien, C., and Freire, M. (2003) J. Biol. Chem. 278, 13286-13293
19. Choi, S. J., Reddy, S. V., Devlin, R. D., Menaa, C., Chung, H., Boyce, B. F., and Roodman, G. D. (1999) J. Biol. Chem. 274, 27747-27753
20. Shirahama-Noda, K., Yamamoto, A., Sugihara, K., Hashimoto, N., Asano, M., Nishimura, M., and Hara-Nishimura, I. (May 29, 2003) J. Biol. Chem. 10.1074/jbc.M302742200
21. Kuroyanagi, M., Nishimura, M., and Hara-Nishimura, I. (2002) Plant Cell Physiol. 43, 143-151
22. Hiraiwa, N., Nishimura, M., and Hara-Nishimura, I. (1999) FEBS Lett. 447, 213-216
23. Caffrey, C. R., Mathieu, M. A., Gaffney, A. M., Salter, J. P., Sajid, M., Lucas, K. D., Franklin, C., Bogyo, M., and McKerrow, J. H. (2000) FEBS Lett. 466, 244-248
24. Halfon, S., Patel, S., Vega, F., Zurawski, S., and Zurawski, G. (1998) FEBS Lett. 438, 114-118
25. Chen, J. M., Fortunato, M., and Barrett, A. J. (2000) Biochem. J. 352, 327-334
26. Lanzavecchia, A. (1985) Nature 314, 537-539
27. Ding, S., Yao, D., Burchell, B., Wolf, C. R., and Friedberg, T. (1997) Arch. Biochem. Biophys. 348, 403-410
28. Johansen, H. T., Knight, C. G., and Barrett, A. J. (1999) Anal. Biochem. 273, 278-283
29. Sallusto, F., and Lanzavecchia, A. (1994) J. Exp. Med. 179, 1109-1118
30. Schimke, R. T., Kaufman, R. J., Alt, F. W., and Kellems, R. F. (1978) Science 202, 1051-1055.21
31. Kaufman, R. J., Bertino, J. R., and Schimke, R. T. (1978) J. Biol. Chem. 253, 5852-5860
32. Rome, L. H., Weissmann, B., and Neufeld, E. F. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 2331-2334
33. Mach, L., Mort, J. S., and Glossl, J. (1994) J. Biol. Chem. 269, 13030-13035
34. Menard, R., Carmona, E., Takebe, S., Dufour, E., Plouffe, C., Mason, P., and Mort, J. S. (1998) J. Biol. Chem. 273, 4478-4484
35. Rozman, J., Stojan, J., Kuhelj, R., Turk, V., and Turk, B. (1999) FEBS Lett. 459, 358-362
36. Quraishi, O., and Storer, A. C. (2001) J. Biol. Chem. 276, 8118-8124
37. Alvarez-Fernandez, M., Barrett, A. J., Gerhartz, B., Dando, P. M., Ni, J., and Abrahamson, M. (1999) J. Biol. Chem. 272, 19195-19203
38. Pierre, P., and Mellman, I. (1998) Cell 93, 1135-1145
39. Hashimoto, S., Suzuki, T., Dong, H. Y., Yamazaki, N., and Matsushima, K. (1999) Blood 94, 837-844
40. Hashimoto, S., Suzuki, T., Dong, H. Y., Nagai, S., Yamazaki, N., and Matsushima, K. (1999) Blood 94, 845-852
41. Dando, P. M., Fortunato, M., Smith, L., Knight, C. G., McKendrick, J. E., and Barrett, A. J. (1999) Biochem. J. 339, 743-749
42. Yamada, K., Shimada, T., Kondo, M., Nishimura, M., and Hara-Nishimura, I. (1999) J. Biol. Chem. 274, 2563-2570
43. Mathieu, M. A., Bogyo, M., Caffrey, C. R., Choe, Y., Lee, J., Chapman, H., Sajid, M., Craik, C. S., and McKerrow, J. H. (2002) Mol. Biochem. Parasitol. 121, 99-105
44. Coulombe, R., Grochulski, P., Sivaraman, J., Menard, R., Mort, J. S., and Cygler, M. (1996) EMBO 15, 5492-5503
45. Cygler, M., Sivaraman, J., Grochulski, P., Coulombe, R., Storer, A. C., and Mort, J. S. (1996) Structure 4, 405-416
46. Podobnik, M., Kuhelj, R., Turk, V., and Turk, D. (1997) J. Mol. Biol. 271, 774-788
47. LaLonde, J. M., Zhao, B., Janson, C. A., D'Alessio, K. J., McQueney, M. S., Orsini, M. J., Debouck, C. M., and Smith, W. W. (1999) Biochemistry 38, 862-869
48. Earnshaw, W. C., Martins, L. M., and Kaufmann, S. H. (1999) Annu. Rev. Biochem. 68, 383-424
49. Boatright, K. M., Renatus, M., Scott, F. L., Sperandio, S., Shin, H., Pedersen, I. M., Ricci, J. E., Edris, W. A., Sutherlin, D. P., Green, D. R., and Salvesen, G. S. (2003) Mol. Cell 11, 529-541
50. Waizenegger, I., Gimenez-Abian, J. F., Wernic, D., and Peters, J. M. (2002) Curr. Biol. 12, 1368-1378
51. Mikolajczyk, J., Boatright, K. M., Stennicke, H. R., Nazif, T., Potempa, J., Bogyo, M., and Salvesen, G. S. (2003) J. Biol. Chem. 278, 10458-10464
52. Inaba, K., Turley, S., Iyoda, T., Yamaide, F., Shimoyama, S., Reis e Sousa, C., Germain, R. N., Mellman, I., and Steinman, R. M. (2000) J. Exp. Med. 191, 927-936
53. Turley, S. J., Inaba, K., Garrett, W. S., Ebersold, M., Unternaehrer, J., Steinman, R. M., and Mellman, I. (2000) Science 288, 522-527
54. Cella, M., Engering, A., Pinet, V., Pieters, J., and Lanzavecchia, A. (1997) Nature 388, 782-787
55. Villadangos, J. A., Cardoso, M., Steptoe, R. J., van Berkel, D., Pooley, J., Carbone, F. R., and Shortman, K. (2001) Immunity 14, 739-749
56. Trombetta, E. S., Ebersold, M., Garrett, W., Pypaert, M., and Mellman, I. (2003) Science 299, 1400-1403