메뉴 건너뛰기




Volumn 3 JUL, Issue , 2012, Pages

The role of astroglia in the epileptic brain

Author keywords

Astrocyte; Epilepsy; Glial neuronal interactions; Ictal event; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; AMPA RECEPTOR; ANTICONVULSIVE AGENT; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1BETA; ION CHANNEL; METHIONINE SULFOXIMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VANILLOID RECEPTOR 1;

EID: 84866143592     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00132     Document Type: Article
Times cited : (38)

References (190)
  • 2
    • 9344259114 scopus 로고    scopus 로고
    • Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport
    • Amiry-Moghaddam, M., Frydenlund, D. S., and Ottersen, O. P. (2004). Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport. Neuroscience 129, 999-1010.
    • (2004) Neuroscience , vol.129 , pp. 999-1010
    • Amiry-Moghaddam, M.1    Frydenlund, D.S.2    Ottersen, O.P.3
  • 4
    • 0026065547 scopus 로고
    • Seizure and acute osmotic change: clinical and neurophysiological aspects
    • Andrew, R. D. (1991). Seizure and acute osmotic change: clinical and neurophysiological aspects. J. Neurol.Sci. 101,7-18.
    • (1991) J. Neurol. Sci. , vol.101 , pp. 7-18
    • Andrew, R.D.1
  • 5
    • 3843109172 scopus 로고    scopus 로고
    • Glu-tamate released from glial cells synchronizes neuronal activity in the hippocampus
    • Angulo, M. C., Kozlov, A. S., Charpak, S., and Audinat, E. (2004). Glu-tamate released from glial cells synchronizes neuronal activity in the hippocampus. J. Neurosci. 24, 6920-6927.
    • (2004) J. Neurosci. , vol.24 , pp. 6920-6927
    • Angulo, M.C.1    Kozlov, A.S.2    Charpak, S.3    Audinat, E.4
  • 7
    • 0033135292 scopus 로고    scopus 로고
    • Tripartite synapses: glia, the unacknowledged partner
    • Araque, A., Parpura, V., Sanzgiri, R. P., and Haydon, P. G. (1999). Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci. 22, 208-215.
    • (1999) Trends Neurosci , vol.22 , pp. 208-215
    • Araque, A.1    Parpura, V.2    Sanzgiri, R.P.3    Haydon, P.G.4
  • 8
    • 0000926233 scopus 로고    scopus 로고
    • Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy
    • Aronica, E., Van Vliet, E. A., Mayboroda, O. A., Troost, D., Da Silva, F. H., and Gorter, J. A. (2000). Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur. J. Neurosci. 12, 2333-2344.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 2333-2344
    • Aronica, E.1    Van Vliet, E.A.2    Mayboroda, O.A.3    Troost, D.4    Da Silva, F.H.5    Gorter, J.A.6
  • 10
    • 80052026214 scopus 로고    scopus 로고
    • GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity
    • Avoli, M., and de Curtis, M. (2011). GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity. Prog. Neurobiol. 95,104-132.
    • (2011) Prog. Neurobiol. , vol.95 , pp. 104-132
    • Avoli, M.1    de Curtis, M.2
  • 11
    • 35449002927 scopus 로고    scopus 로고
    • Aquaporins in the brain: from aqueduct to "multiduct"
    • Badaut, J., Brunet, J. F., and Regli, L. (2007). Aquaporins in the brain: from aqueduct to "multiduct". Metab. Brain Dis. 22, 251-263.
    • (2007) Metab. Brain Dis. , vol.22 , pp. 251-263
    • Badaut, J.1    Brunet, J.F.2    Regli, L.3
  • 13
    • 58149105502 scopus 로고    scopus 로고
    • A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β
    • Balosso, S., Maroso, M., Sanchez-Alavez, M., Ravizza, T., Frasca, A., Bartfai, T., and Vezzani, A. (2008). A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1β. Brain 131, 3256-3265.
    • (2008) Brain , vol.131 , pp. 3256-3265
    • Balosso, S.1    Maroso, M.2    Sanchez-Alavez, M.3    Ravizza, T.4    Frasca, A.5    Bartfai, T.6    Vezzani, A.7
  • 14
    • 0030083104 scopus 로고    scopus 로고
    • Induction of astroglial gene expression by experimental seizures in the rat: spatio-temporal patterns of the early stages
    • Belluardo, N., Mudo, G., Jiang, X. H., and Condorelli, D. E (1996). Induction of astroglial gene expression by experimental seizures in the rat: spatio-temporal patterns of the early stages. Glia 16,174-186.
    • (1996) Glia , vol.16 , pp. 174-186
    • Belluardo, N.1    Mudo, G.2    Jiang, X.H.3    Condorelli, D.E.4
  • 16
    • 33748417555 scopus 로고    scopus 로고
    • Endogenous neurosteroids modulate epileptoge-nesis in a model of temporal lobe epilepsy
    • Biagini, G., Baldelli, E., Longo, D., Pradelli, L., Zini, I., Rogawski, M. A., and Avoli, M. (2006). Endogenous neurosteroids modulate epileptoge-nesis in a model of temporal lobe epilepsy. Exp. Neurol. 201, 519-524.
    • (2006) Exp. Neurol. , vol.201 , pp. 519-524
    • Biagini, G.1    Baldelli, E.2    Longo, D.3    Pradelli, L.4    Zini, I.5    Rogawski, M.A.6    Avoli, M.7
  • 17
    • 58149280525 scopus 로고    scopus 로고
    • Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period
    • Biagini, G., Longo, D., Baldelli, E., Zoli, M., Rogawski, M. A., Bertazzoni, G., and Avoli, M. (2009). Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia 50(SUPPL. 1), 53-58.
    • (2009) Epilepsia , vol.50 , Issue.SUPPL. 1 , pp. 53-58
    • Biagini, G.1    Longo, D.2    Baldelli, E.3    Zoli, M.4    Rogawski, M.A.5    Bertazzoni, G.6    Avoli, M.7
  • 18
  • 19
    • 33748857971 scopus 로고    scopus 로고
    • Functional changes in astroglial cells in epilepsy
    • Binder, D. K., and Steinhauser, C. (2006). Functional changes in astroglial cells in epilepsy. Glia 54, 358-368.
    • (2006) Glia , vol.54 , pp. 358-368
    • Binder, D.K.1    Steinhauser, C.2
  • 20
    • 70349134701 scopus 로고    scopus 로고
    • Astrocyte function and role in motor neuron disease: a future therapeutic target? Glia
    • Blackburn, D., Sargsyan, S., Monk, P. N., and Shaw, P. J. (2009). Astrocyte function and role in motor neuron disease: a future therapeutic target? Glia 57, 1251-1264.
    • (2009) , vol.57 , pp. 1251-1264
    • Blackburn, D.1    Sargsyan, S.2    Monk, P.N.3    Shaw, P.J.4
  • 22
    • 13544274000 scopus 로고    scopus 로고
    • Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies
    • Boison, D. (2005). Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies. Neuro-scientist 11,25-36.
    • (2005) Neuro-scientist , vol.11 , pp. 25-36
    • Boison, D.1
  • 23
    • 39149122180 scopus 로고    scopus 로고
    • The adenosine kinase hypothesis of epileptogenesis
    • Boison, D. (2008). The adenosine kinase hypothesis of epileptogenesis. Prog. Neurobiol. 84, 249-262.
    • (2008) Prog. Neurobiol. , vol.84 , pp. 249-262
    • Boison, D.1
  • 24
    • 79952552594 scopus 로고    scopus 로고
    • Adenosine dysfunction and adenosine kinase in epileptogenesis
    • Boison, D. (2010). Adenosine dysfunction and adenosine kinase in epileptogenesis. Open Neurosci. J. 4, 93-101.
    • (2010) Open Neurosci. J. , vol.4 , pp. 93-101
    • Boison, D.1
  • 25
    • 0032169291 scopus 로고    scopus 로고
    • Properties of human glial cells associated with epileptic seizure foci
    • Bordey, A., and Sontheimer, H. (1998). Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res. 32,286-303.
    • (1998) Epilepsy Res , vol.32 , pp. 286-303
    • Bordey, A.1    Sontheimer, H.2
  • 27
    • 0032940256 scopus 로고    scopus 로고
    • Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy
    • Bouilleret, V., Ridoux, V., Depaulis, A., Marescaux, C., Nehlig, A., and Le Gal La Salle, G. (1999). Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy. Neu-roscience 89, 717-729.
    • (1999) Neu-roscience , vol.89 , pp. 717-729
    • Bouilleret, V.1    Ridoux, V.2    Depaulis, A.3    Marescaux, C.4    Nehlig, A.5    Le Gal La Salle, G.6
  • 28
    • 0029592665 scopus 로고
    • Glutamate GABA and epilepsy
    • Bradford, H. F. (1995). Glutamate, GABA and epilepsy. Prog. Neurobiol. 47,477-511.
    • (1995) Prog. Neurobiol , vol.47 , pp. 477-511
    • Bradford, H.F.1
  • 29
    • 0036917060 scopus 로고    scopus 로고
    • Long-lasting modulation of synaptic input to Purkinje neurons by Bergmann glia stimulation in rat brain slices
    • Brockhaus, J.,and Deitmer, J. W. (2002). Long-lasting modulation of synaptic input to Purkinje neurons by Bergmann glia stimulation in rat brain slices. J. Physiol. 545, 581-593.
    • (2002) J. Physiol. , vol.545 , pp. 581-593
    • Brockhaus, J.1    Deitmer, J.W.2
  • 31
    • 80052855507 scopus 로고    scopus 로고
    • Purinergic signalling: from normal behaviour to pathological brain function
    • Burnstock, G., Krugel, U., Abbracchio, M. P., and Illes, P. (2011). Purinergic signalling: from normal behaviour to pathological brain function. Prog. Neurobiol. 95, 229-274.
    • (2011) Prog. Neurobiol. , vol.95 , pp. 229-274
    • Burnstock, G.1    Krugel, U.2    Abbracchio, M.P.3    Illes, P.4
  • 32
    • 0034672940 scopus 로고    scopus 로고
    • Reciprocal communication systems between astrocytes and neurones
    • Carmignoto, G. (2000). Reciprocal communication systems between astrocytes and neurones. Prog. Neurobiol. 62, 561-581.
    • (2000) Prog. Neurobiol. , vol.62 , pp. 561-581
    • Carmignoto, G.1
  • 33
    • 77952423623 scopus 로고    scopus 로고
    • The contribution of astrocyte signalling to neurovascu-lar coupling
    • Carmignoto, G., and Gomez-Gonzalo, M. (2010). The contribution of astrocyte signalling to neurovascu-lar coupling. Brain Res. Rev. 63, 138-148.
    • (2010) Brain Res. Rev , vol.63 , pp. 138-148
    • Carmignoto, G.1    Gomez-Gonzalo, M.2
  • 35
    • 0028879447 scopus 로고
    • Hypo-tonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices
    • Chebabo, S. R., Hester, M. A., Aitken, P. G., and Somjen, G. G. (1995). Hypo-tonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices. Brain Res. 695, 203-216.
    • (1995) Brain Res , vol.695 , pp. 203-216
    • Chebabo, S.R.1    Hester, M.A.2    Aitken, P.G.3    Somjen, G.G.4
  • 38
    • 3042649213 scopus 로고    scopus 로고
    • GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications
    • Conti, F., Pinelli, A., and Melone, M. (2004). GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications. Brain Res. Rev. 45, 196-212.
    • (2004) Brain Res. Rev , vol.45 , pp. 196-212
    • Conti, F.1    Pinelli, A.2    Melone, M.3
  • 40
    • 13144307111 scopus 로고    scopus 로고
    • Multiple facets of GABAergic neurons and synapses: multiple fates of GABA signalling in epilepsies
    • Cossart, R., Bernard, C., and Ben-Ari, Y. (2005). Multiple facets of GABAergic neurons and synapses: multiple fates of GABA signalling in epilepsies. Trends Neurosci. 28,108-115.
    • (2005) Trends Neurosci , vol.28 , pp. 108-115
    • Cossart, R.1    Bernard, C.2    Ben-Ari, Y.3
  • 42
    • 36448995383 scopus 로고    scopus 로고
    • Does glutamate released by astrocytes cause focal epilepsy?
    • D'Ambrosio, R. (2006). Does glutamate released by astrocytes cause focal epilepsy? Epilepsy Curr. 6, 173-176.
    • (2006) Epilepsy Curr , vol.6 , pp. 173-176
    • D'Ambrosio, R.1
  • 43
    • 0026503603 scopus 로고
    • Neuronal activity triggers calcium waves in hippocampal astrocyte networks
    • Dani, J. W., Chernjavsky, A., and Smith, S. J. (1992). Neuronal activity triggers calcium waves in hippocampal astrocyte networks. Neuron 8, 429-440.
    • (1992) Neuron , vol.8 , pp. 429-440
    • Dani, J.W.1    Chernjavsky, A.2    Smith, S.J.3
  • 44
    • 69449102409 scopus 로고    scopus 로고
    • Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?
    • David, Y., Cacheaux, L. P., Ivens, S., Lapilover, E., Heinemann, U., Kaufer, D., and Friedman, A. (2009). Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? J. Neurosci. 29, 10588-10599.
    • (2009) J Neurosci , vol.29 , pp. 10588-10599
    • David, Y.1    Cacheaux, L.P.2    Ivens, S.3    Lapilover, E.4    Heinemann, U.5    Kaufer, D.6    Friedman, A.7
  • 47
    • 35448989687 scopus 로고    scopus 로고
    • Conditional knock-out of Kir 4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation
    • Djukic, B., Casper, K. B., Philpot, B. D., Chin, L. S., and McCarthy, K. D. (2007). Conditional knock-out of Kir 4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J. Neurosci. 27, 11354-11365.
    • (2007) J. Neurosci. , vol.27 , pp. 11354-11365
    • Djukic, B.1    Casper, K.B.2    Philpot, B.D.3    Chin, L.S.4    McCarthy, K.D.5
  • 48
    • 0025635679 scopus 로고
    • Osmolality-induced changes in extracellular volume alter epileptiform bursts independent of chemical synapses in the rat: importance of non-synaptic mechanisms in hippocampal epileptogenesis
    • Dudek, F. E., Obenaus, A., and Tasker, J. G. (1990). Osmolality-induced changes in extracellular volume alter epileptiform bursts independent of chemical synapses in the rat: importance of non-synaptic mechanisms in hippocampal epileptogenesis. Neurosci. Lett. 120, 267-270.
    • (1990) Neurosci. Lett. , vol.120 , pp. 267-270
    • Dudek, F.E.1    Obenaus, A.2    Tasker, J.G.3
  • 49
    • 0032293649 scopus 로고    scopus 로고
    • 'Non-synaptic' mechanisms in seizures and epileptogenesis
    • Dudek, F. E., Yasumura, T., and Rash, J. E. (1998). 'Non-synaptic' mechanisms in seizures and epileptogenesis. Cell Biol. Int. 22, 793-805.
    • (1998) Cell Biol. Int. , vol.22 , pp. 793-805
    • Dudek, F.E.1    Yasumura, T.2    Rash, J.E.3
  • 50
    • 0029117646 scopus 로고
    • Adrenergic calcium signaling in astrocyte networks within the hippocampal slice
    • Duffy, S., and MacVicar, B. A. (1995). Adrenergic calcium signaling in astrocyte networks within the hippocampal slice. J. Neurosci. 15, 5535-5550.
    • (1995) J. Neurosci. , vol.15 , pp. 5535-5550
    • Duffy, S.1    MacVicar, B.A.2
  • 51
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During, M. J., and Spencer, D. D. (1993). Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 341,1607-1610.
    • (1993) Lancet , vol.341 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 53
    • 38449093605 scopus 로고    scopus 로고
    • Glutamate and astrocytes - key players in human mesial temporal lobe epilepsy?
    • Eid, T., Williamson, A., Lee, T. S., Petroff, O. A., and De Lanerolle, N. C. (2008b). Glutamate and astrocytes - key players in human mesial temporal lobe epilepsy? Epilepsia 49(SUPPL. 2), 42-52.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 2 , pp. 42-52
    • Eid, T.1    Williamson, A.2    Lee, T.S.3    Petroff, O.A.4    De Lanerolle, N.C.5
  • 54
    • 9144228368 scopus 로고    scopus 로고
    • Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy
    • Eid, T., Thomas, M. J., Spencer, D. D., Runden-Pran, E., Lai, J. C., Malthankar, G. V., Kim, J. H., Danbolt, N. C., Ottersen, O. P., and De Lanerolle, N. C. (2004). Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy. Lancet 363, 28-37.
    • (2004) Lancet , vol.363 , pp. 28-37
    • Eid, T.1    Thomas, M.J.2    Spencer, D.D.3    Runden-Pran, E.4    Lai, J.C.5    Malthankar, G.V.6    Kim, J.H.7    Dan-bolt, N.C.8    Ottersen, O.P.9    De Lanerolle, N.C.10
  • 55
  • 56
    • 37249054686 scopus 로고    scopus 로고
    • Astrocytes control neuronal excitability in the nucleus accumbens
    • Fellin, T., D'Ascenzo, M., and Hay-don, P. G. (2007). Astrocytes control neuronal excitability in the nucleus accumbens. ScientificWorld-Journal 7, 89-97.
    • (2007) ScientificWorld-Journal , vol.7 , pp. 89-97
    • Fellin, T.1    D'Ascenzo, M.2    Hay-don, P.G.3
  • 57
    • 33748518188 scopus 로고    scopus 로고
    • Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices
    • Fellin, T., Gomez-Gonzalo, M., Gobbo, S., Carmignoto, G., and Haydon, P. G. (2006a). Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices. J. Neurosci. 26, 9312-9322.
    • (2006) J. Neurosci. , vol.26 , pp. 9312-9322
    • Fellin, T.1    Gomez-Gonzalo, M.2    Gobbo, S.3    Carmignoto, G.4    Haydon, P.G.5
  • 58
    • 33645223314 scopus 로고    scopus 로고
    • Purinergic receptors mediate two distinct glutamate release pathways in hippocampal astrocytes
    • Fellin, T., Pozzan, T., and Carmignoto, G. (2006b). Purinergic receptors mediate two distinct glutamate release pathways in hippocampal astrocytes. J. Biol. Chem. 281, 4274-4284.
    • (2006) J. Biol. Chem. , vol.281 , pp. 4274-4284
    • Fellin, T.1    Pozzan, T.2    Carmignoto, G.3
  • 59
    • 28244439209 scopus 로고    scopus 로고
    • Do astrocytes contribute to excitation underlying seizures?
    • Fellin, T., and Haydon, P. G. (2005). Do astrocytes contribute to excitation underlying seizures? Trends Mol.Med. 11,530-533.
    • (2005) Trends Mol Med , vol.11 , pp. 530-533
    • Fellin, T.1    Haydon, P.G.2
  • 60
    • 4444320120 scopus 로고    scopus 로고
    • Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynap-tic NMDA receptors
    • Fellin, T., Pascual, O., Gobbo, S., Pozzan, T., Haydon, P. G., and Carmignoto, G. (2004). Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynap-tic NMDA receptors. Neuron 43, 729-743.
    • (2004) Neuron , vol.43 , pp. 729-743
    • Fellin, T.1    Pascual, O.2    Gobbo, S.3    Pozzan, T.4    Haydon, P.G.5    Carmignoto, G.6
  • 62
    • 79956307099 scopus 로고    scopus 로고
    • Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice
    • Florian, C., Vecsey, C. G., Halassa, M. M., Haydon, P. G., and Abel, T. (2011). Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice. J. Neurosci. 31, 6956-6962.
    • (2011) J. Neurosci. , vol.31 , pp. 6956-6962
    • Florian, C.1    Vecsey, C.G.2    Halassa, M.M.3    Haydon, P.G.4    Abel, T.5
  • 63
    • 67650465533 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy
    • Friedman, A., Kaufer, D., and Heine-mann, U. (2009). Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy. Epilepsy Res. 85, 142-149.
    • (2009) Epilepsy Res , vol.85 , pp. 142-149
    • Friedman, A.1    Kaufer, D.2    Heine-mann, U.3
  • 64
    • 84890883246 scopus 로고    scopus 로고
    • Epilepsy E/I balance and GABAA receptor plasticity
    • doi:10.3389/neuro.02.005.2008
    • Fritschy, J. M. (2008). Epilepsy, E/I balance and GABAA receptor plasticity. Front. Mol. Neurosci. 1:5. doi:10.3389/neuro.02.005.2008
    • (2008) Front. Mol. Neurosci. , vol.1 , pp. 5
    • Fritschy, J.M.1
  • 65
    • 0028845558 scopus 로고
    • Neurochemical and morphological changes associated with human epilepsy
    • Glass, M., and Dragunow, M. (1995). Neurochemical and morphological changes associated with human epilepsy. Brain Res. Brain Res. Rev. 21,29-41.
    • (1995) Brain Res. Brain Res. Rev , vol.21 , pp. 29-41
    • Glass, M.1    Dragunow, M.2
  • 67
    • 0842284006 scopus 로고    scopus 로고
    • Over-expression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis
    • Gouder, N., Scheurer, L., Fritschy, J. M., and Boison, D. (2004). Over-expression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. J. Neurosci. 24, 692-701.
    • (2004) J. Neurosci. , vol.24 , pp. 692-701
    • Gouder, N.1    Scheurer, L.2    Fritschy, J.M.3    Boison, D.4
  • 68
    • 68749119353 scopus 로고    scopus 로고
    • Tripartite synapses: roles for astrocytic purines in the control of synaptic physiology and behavior
    • Halassa, M. M., Fellin, T., and Haydon, P. G. (2009). Tripartite synapses: roles for astrocytic purines in the control of synaptic physiology and behavior. Neuropharmacology 57, 343-346.
    • (2009) Neuropharmacology , vol.57 , pp. 343-346
    • Halassa, M.M.1    Fellin, T.2    Haydon, P.G.3
  • 69
    • 77957090798 scopus 로고    scopus 로고
    • Reactive astrocytes as therapeutic targets for CNS disorders
    • Hamby, M. E., and Sofroniew, M. V. (2010). Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics 7, 494-506.
    • (2010) Neurotherapeutics , vol.7 , pp. 494-506
    • Hamby, M.E.1    Sofroniew, M.V.2
  • 70
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovas-cular coupling
    • Haydon, P. G., and Carmignoto, G. (2006). Astrocyte control of synaptic transmission and neurovas-cular coupling. Physiol. Rev. 86, 1009-1031.
    • (2006) Physiol. Rev. , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 72
    • 0022586049 scopus 로고
    • Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue
    • Heinemann, U., Konnerth, A., Pumain, R., and Wadman, W. J. (1986). Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue. Adv. Neurol. 44, 641-661.
    • (1986) Adv. Neurol. , vol.44 , pp. 641-661
    • Heinemann, U.1    Konnerth, A.2    Pumain, R.3    Wadman, W.J.4
  • 73
    • 0017362119 scopus 로고
    • Extracellular free calcium and potassium during paroxsmal activity in the cerebral cortex of the cat. Exp
    • Heinemann, U., Lux, H. D., and Gut-nick, M. J. (1977). Extracellular free calcium and potassium during paroxsmal activity in the cerebral cortex of the cat. Exp. Brain Res. 27, 237-243.
    • (1977) Brain Res , vol.27 , pp. 237-243
    • Heinemann, U.1    Lux, H.D.2    Gut-nick, M.J.3
  • 74
    • 0034838263 scopus 로고    scopus 로고
    • An inwardly rectifying K+ channel, Kir4.1, expressed in astrocytes surrounds synapses and bloodvessels in brain
    • Higashi, K., Fujita, A., Inanobe, A., Tanemoto, M., Doi, K., Kubo, T., and Kurachi,Y. (2001). An inwardly rectifying K+ channel, Kir4.1, expressed in astrocytes surrounds synapses and bloodvessels in brain. Am. J. Physiol. Cell Physiol. 281, C922-C931.
    • (2001) Am. J. Physiol. Cell Physiol. , vol.281
    • Higashi, K.1    Fujita, A.2    Inanobe, A.3    Tanemoto, M.4    Doi, K.5    Kubo, T.6    Kurachi, Y.7
  • 77
    • 2442699087 scopus 로고    scopus 로고
    • Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excita tion of hippocampal interneurons
    • Huang, Y. H., Sinha, S. R., Tanaka, K., Rothstein, J. D., and Bergles, D. E. (2004). Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excita tion of hippocampal interneurons. J. Neurosci. 24, 4551-4559.
    • (2004) J. Neurosci. , vol.24 , pp. 4551-4559
    • Huang, Y.H.1    Sinha, S.R.2    Tanaka, K.3    Rothstein, J.D.4    Bergles, D.E.5
  • 80
    • 0030831943 scopus 로고    scopus 로고
    • Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals
    • Ishii, M., Horio, Y., Tada, Y., Hibino, H., Inanobe, A., Ito, M., Yamada, M., Gotow, T., Uchiyama, Y., and Kurachi, Y (1997). Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals. J.Neurosci. 17,7725-7735.
    • (1997) J. Neurosci. , vol.17 , pp. 7725-7735
    • Ishii, M.1    Horio, Y.2    Tada, Y.3    Hibino, H.4    Inanobe, A.5    Ito, M.6    Yamada, M.7    Gotow, T.8    Uchiyama, Y.9    Kurachi, Y.10
  • 82
    • 0347623321 scopus 로고    scopus 로고
    • Models and mechanisms of experimental epilepsies
    • Jefferys, J. G. R. (2003). Models and mechanisms of experimental epilepsies. Epilepsia 44(SUPPL. 12), 44-50.
    • (2003) Epilepsia , vol.44 , Issue.SUPPL 12 , pp. 44-50
    • Jefferys, J.G.R.1
  • 84
    • 34548178798 scopus 로고    scopus 로고
    • Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle
    • Kam, K., and Nicoll, R. (2007). Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle. J. Neurosci. 27, 9192-9200.
    • (2007) J. Neurosci. , vol.27 , pp. 9192-9200
    • Kam, K.1    Nicoll, R.2
  • 85
    • 0032247897 scopus 로고    scopus 로고
    • Astrocyte-mediated potentiation of inhibitory synaptic transmission
    • Kang, J., Jiang, L., Goldman, S. A., and Nedergaard, M. (1998). Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat. Neurosci. 1,683-692.
    • (1998) Nat. Neurosci. , vol.1 , pp. 683-692
    • Kang, J.1    Jiang, L.2    Goldman, S.A.3    Nedergaard, M.4
  • 86
    • 28044436908 scopus 로고    scopus 로고
    • Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons
    • Kang, N., Xu, J., Xu, Q., Nedergaard, M., and Kang, J. (2005). Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. J. Neurophysiol. 94, 4121-4130.
    • (2005) J. Neurophysiol. , vol.94 , pp. 4121-4130
    • Kang, N.1    Xu, J.2    Xu, Q.3    Nedergaard, M.4    Kang, J.5
  • 88
    • 0034255132 scopus 로고    scopus 로고
    • Genetic inac-tivation of an inwardly rectifying potassium channel (Kir4 1 subunit) in mice: phenotypic impact in retina
    • Kofuji, P., Ceelen, P., Zahs, K. R., Surbeck, L. W., Lester, H. A., and Newman,E. A. (2000). Genetic inac-tivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina. J. Neurosci. 20, 5733-5740.
    • (2000) J. Neurosci. , vol.20 , pp. 5733-5740
    • Kofuji, P.1    Ceelen, P.2    Zahs, K.R.3    Surbeck, L.W.4    Lester, H.A.5    Newman, E.A.6
  • 89
    • 9344266325 scopus 로고    scopus 로고
    • Potassium buffering in the central nervous system
    • Kofuji, P., and Newman, E. A. (2004). Potassium buffering in the central nervous system. Neuroscience 129, 1045-1056.
    • (2004) Neuroscience , vol.129 , pp. 1045-1056
    • Kofuji, P.1    Newman, E.A.2
  • 90
    • 74549174601 scopus 로고    scopus 로고
    • + oscillations: involvement of ATP release in astrocytes
    • + oscillations: involvement of ATP release in astrocytes. FEBS J. 277,286-292.
    • (2010) FEBS J , vol.277 , pp. 286-292
    • Koizumi, S.1
  • 91
    • 0022470412 scopus 로고
    • Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro I. Development of seizurelike activity in low extracellular calcium
    • Konnerth, A., Heinemann, U., and Yaari, Y (1986). Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium. J. Neurophysiol. 56, 409-423.
    • (1986) J. Neurophysiol. , vol.56 , pp. 409-423
    • Konnerth, A.1    Heinemann, U.2    Yaari, Y.3
  • 92
    • 33846862901 scopus 로고    scopus 로고
    • Downregulation of Kir4 1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes
    • Kucheryavykh, Y V., Kucheryavykh, L. Y., Nichols, C. G., Maldonado, H. M., Baksi, K., Reichenbach, A., Skatchkov, S. N., and Eaton, M. J. (2007). Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes. Glia 55,274-281.
    • (2007) Glia , vol.55 , pp. 274-281
    • Kucheryavykh, Y.V.1    Kucheryavykh, L.Y.2    Nichols, C.G.3    Maldonado, H.M.4    Baksi, K.5    Reichenbach, A.6    Skatchkov, S.N.7    Eaton, M.J.8
  • 93
    • 0013924555 scopus 로고
    • Physiological properties of glial cells in the central nervous system of amphibia
    • Kuffler, S. W., Nicholls, J. G., and Orkand, R. K. (1966). Physiological properties of glial cells in the central nervous system of amphibia. J. Neurophysiol. 29, 768-787.
    • (1966) J. Neurophysiol. , vol.29 , pp. 768-787
    • Kuffler, S.W.1    Nicholls, J.G.2    Orkand, R.K.3
  • 94
    • 0033216110 scopus 로고    scopus 로고
    • Neuron-glia signaling via α1 adrenoceptor-mediated Ca2+ release in Bergmann glial cells in situ
    • Kulik, A., Haentzsch, A., Luckermann, M., Reichelt, W., and Ballanyi, K. (1999). Neuron-glia signaling via α1 adrenoceptor-mediated Ca2+ release in Bergmann glial cells in situ. J. Neurosci. 19, 8401-8408.
    • (1999) J. Neurosci. , vol.19 , pp. 8401-8408
    • Kulik, A.1    Haentzsch, A.2    Luckermann, M.3    Reichelt, W.4    Ballanyi, K.5
  • 97
    • 84862782256 scopus 로고    scopus 로고
    • Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis
    • Lee, D. J., Hsu, M. S., Seldin, M. M., Arellano, J. L., and Binder, D. K. (2012). Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis. Exp. Neurol. 235, 246-255.
    • (2012) Exp. Neurol. , vol.235 , pp. 246-255
    • Lee, D.J.1    Hsu, M.S.2    Seldin, M.M.3    Arellano, J.L.4    Binder, D.K.5
  • 99
    • 17044437090 scopus 로고    scopus 로고
    • Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy
    • Lenzen, K. P., Heils, A., Lorenz, S., Hempelmann, A., Hofels, S., Lohoff, E W., Schmitz, B., and Sander, T. (2005). Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy. Epilepsy Res. 63, 113-118.
    • (2005) Epilepsy Res , vol.63 , pp. 113-118
    • Lenzen, K.P.1    Heils, A.2    Lorenz, S.3    Hempelmann, A.4    Hofels, S.5    Lohoff, E.W.6    Schmitz, B.7    Sander, T.8
  • 100
    • 0035138079 scopus 로고    scopus 로고
    • Identification of an inward rectifier potassium channel gene expressed in mouse cortical astrocytes
    • Li, L., Head, V., and Timpe, L. C. (2001). Identification of an inward rectifier potassium channel gene expressed in mouse cortical astrocytes. Glia 33, 57-71.
    • (2001) Glia , vol.33 , pp. 57-71
    • Li, L.1    Head, V.2    Timpe, L.C.3
  • 101
    • 70350440498 scopus 로고    scopus 로고
    • Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice
    • Li, T., Lan, J. Q., and Boison, D. (2008). Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice. Neuron Glia Biol. 4, 91-99.
    • (2008) Neuron Glia Biol , vol.4 , pp. 91-99
    • Li, T.1    Lan, J.Q.2    Boison, D.3
  • 102
    • 46749132311 scopus 로고    scopus 로고
    • Adenosine dysfunction in astrogliosis: cause for seizure generation?
    • Li, T., Quan Lan, J., Fredholm, B. B., Simon, R. P., and Boison, D. (2007). Adenosine dysfunction in astrogliosis: cause for seizure generation? Neuron Glia Biol. 3, 353-366.
    • (2007) Neuron Glia Biol , vol.3 , pp. 353-366
    • Li, T.1    Quan Lan, J.2    Fredholm, B.B.3    Simon, R.P.4    Boison, D.5
  • 103
    • 33748203626 scopus 로고    scopus 로고
    • Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hip-pocampal area CA1
    • Liang, S. L., Carlson, G. C., and Coulter, D. A. (2006). Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hip-pocampal area CA1. J. Neurosci. 26, 8537-8548.
    • (2006) J. Neurosci. , vol.26 , pp. 8537-8548
    • Liang, S.L.1    Carlson, G.C.2    Coulter, D.A.3
  • 104
    • 61849173014 scopus 로고    scopus 로고
    • Rapid plasticity at inhibitory and excitatory synapses in the hippocampus induced by ictal epileptiform discharges
    • Lopantsev, V., Both, M., and Draguhn, A. (2009). Rapid plasticity at inhibitory and excitatory synapses in the hippocampus induced by ictal epileptiform discharges. Eur. J. Neurosci. 29, 1153-1164.
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 1153-1164
    • Lopantsev, V.1    Both, M.2    Draguhn, A.3
  • 106
    • 76749145072 scopus 로고    scopus 로고
    • Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs
    • Madsen, K. K., White, H. S., and Schous-boe, A. (2010). Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs. Pharmacol. Ther. 125,394-401.
    • (2010) Pharmacol. Ther. , vol.125 , pp. 394-401
    • Madsen, K.K.1    White, H.S.2    Schous-boe, A.3
  • 107
    • 33751237994 scopus 로고    scopus 로고
    • Mechanisms of disease: astrocytes in neurodegenerative disease
    • Maragakis, N. J., and Rothstein, J. D. (2006). Mechanisms of disease: astrocytes in neurodegenerative disease. Nat. Clin. Pract. Neurol. 2, 679-689.
    • (2006) Nat. Clin. Pract. Neurol. , vol.2 , pp. 679-689
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 110
    • 0033923678 scopus 로고    scopus 로고
    • Intraoperative hippocampal electro-corticography to predict the extent of hippocampal resection in temporal lobe epilepsy surgery
    • McKhann, G. M. II, Schoenfeld-McNeill, J., Born, D. E., Haglund, M. M., and Ojemann, G. A. (2000). Intraoperative hippocampal electro-corticography to predict the extent of hippocampal resection in temporal lobe epilepsy surgery. J. Neuro-surg. 93, 44-52.
    • (2000) J. Neuro-surg. , vol.93 , pp. 44-52
    • McKhann, G.M.I.I.1    Schoenfeld-McNeill, J.2    Born, D.E.3    Haglund, M.M.4    Ojemann, G.A.5
  • 111
    • 78650425783 scopus 로고    scopus 로고
    • Aquaporin 4 expression in control and epileptic human cerebral cortex
    • Medici, V., Frassoni, C., Tassi, L., Spreafico, R., and Garbelli, R. (2011). Aquaporin 4 expression in control and epileptic human cerebral cortex. Brain Res. 1367,330-339.
    • (2011) Brain Res , vol.1367 , pp. 330-339
    • Medici, V.1    Frassoni, C.2    Tassi, L.3    Spreafico, R.4    Garbelli, R.5
  • 112
    • 0032956181 scopus 로고    scopus 로고
    • Neu-rosteroids: expression of steroido-genic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan, A. G., Do-Rego, J. L., Beaujean, D., Luu-the, V., Pelletier, G., and Vaudry, H. (1999). Neu-rosteroids: expression of steroido-genic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol. Rev. 51, 63-81.
    • (1999) Pharmacol. Rev. , vol.51 , pp. 63-81
    • Mensah-Nyagan, A.G.1    Do-Rego, J.L.2    Beaujean, D.3    Luu-the, V.4    Pelletier, G.5    Vaudry, H.6
  • 113
    • 84860274847 scopus 로고    scopus 로고
    • Astro-cyte signaling controls spike timing-dependent depression at neocortical synapses
    • Min, R., and Nevian, T. (2012). Astro-cyte signaling controls spike timing-dependent depression at neocortical synapses. Nat. Neurosci. 15,746-753.
    • (2012) Nat. Neurosci. , vol.15 , pp. 746-753
    • Min, R.1    Nevian, T.2
  • 114
    • 1542345501 scopus 로고    scopus 로고
    • Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function
    • Müller, S., Ronfani, L., and Bianchi, M. E. (2004). Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function. J. Intern. Med. 255, 332-343.
    • (2004) J. Intern. Med. , vol.255 , pp. 332-343
    • Müller, S.1    Ronfani, L.2    Bianchi, M.E.3
  • 115
    • 9344269387 scopus 로고    scopus 로고
    • Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR41
    • Nagelhus, E. A., Mathiisen, T. M., and Ottersen, O. P. (2004). Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4.1. Neuro-science 129,905-913.
    • (2004) Neuro-science , vol.129 , pp. 905-913
    • Nagelhus, E.A.1    Mathiisen, T.M.2    Ottersen, O.P.3
  • 116
    • 40849100074 scopus 로고    scopus 로고
    • Endocannabinoids mediate neuron-astrocyte communication
    • Navarrete, M., and Araque, A. (2008). Endocannabinoids mediate neuron-astrocyte communication. Neuron 57, 883-893.
    • (2008) Neuron , vol.57 , pp. 883-893
    • Navarrete, M.1    Araque, A.2
  • 117
    • 77957299242 scopus 로고    scopus 로고
    • Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes
    • Navarrete, M., and Araque, A. (2010). Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes. Neuron 68, 113-126.
    • (2010) Neuron , vol.68 , pp. 113-126
    • Navarrete, M.1    Araque, A.2
  • 119
    • 0028212163 scopus 로고
    • Direct signaling from astrocytes to neurons in cultures of mammalian brain cells
    • Nedergaard, M. (1994). Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science 263, 1768-1771.
    • (1994) Science , vol.263 , pp. 1768-1771
    • Nedergaard, M.1
  • 121
    • 0027184270 scopus 로고
    • Inward-rectifying potassium channels in retinal glial (Müller) cells
    • Newman, E. A. (1993). Inward-rectifying potassium channels in retinal glial (Müller) cells. J. Neurosci. 13, 3333-3345.
    • (1993) J. Neurosci. , vol.13 , pp. 3333-3345
    • Newman, E.A.1
  • 122
    • 77951590218 scopus 로고    scopus 로고
    • Estimation of the burden of active and life-time epilepsy: a meta-analytic approach
    • Ngugi, A. K., Bottomley, C., Klein-schmidt, I., Sander, J. W., and Newton, C. R. (2010). Estimation of the burden of active and life-time epilepsy: a meta-analytic approach. Epilepsia 51, 883-890.
    • (2010) Epilepsia , vol.51 , pp. 883-890
    • Ngugi, A.K.1    Bottomley, C.2    Klein-schmidt, I.3    Sander, J.W.4    Newton, C.R.5
  • 123
    • 0031022918 scopus 로고    scopus 로고
    • Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
    • Nielsen, S., Nagelhus, E. A., Amiry-Moghaddam, M., Bourque, C., Agre, P., and Ottersen, O. P. (1997). Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J. Neurosci. 17, 171-180.
    • (1997) J. Neurosci. , vol.17 , pp. 171-180
    • Nielsen, S.1    Nagelhus, E.A.2    Amiry-Moghaddam, M.3    Bourque, C.4    Agre, P.5    Ottersen, O.P.6
  • 125
  • 126
    • 53749085877 scopus 로고    scopus 로고
    • Functional implications for Kir4 1 channels in glial biology: from K+ buffering to cell differentiation
    • Olsen, M. L., and Sontheimer, H. (2008). Functional implications for Kir4.1 channels in glial biology: from K+ buffering to cell differentiation. J. Neurochem. 107, 589-601.
    • (2008) J. Neurochem. , vol.107 , pp. 589-601
    • Olsen, M.L.1    Sontheimer, H.2
  • 127
    • 0013926565 scopus 로고
    • Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia
    • Orkand, R. K., Nicholls, J. G., and Kuffler, S. W. (1966). Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J. Neurophysiol. 29, 788-806.
    • (1966) J. Neurophysiol. , vol.29 , pp. 788-806
    • Orkand, R.K.1    Nicholls, J.G.2    Kuffler, S.W.3
  • 129
    • 0032531028 scopus 로고    scopus 로고
    • Anion currents and predicted glutamate flux through a neuronal glutamate transporter
    • Otis, T. S., and Jahr, C. E. (1998). Anion currents and predicted glutamate flux through a neuronal glutamate transporter. J. Neurosci. 18, 7099-7110.
    • (1998) J. Neurosci. , vol.18 , pp. 7099-7110
    • Otis, T.S.1    Jahr, C.E.2
  • 130
    • 0029944481 scopus 로고    scopus 로고
    • Influence of osmolality on seizure amplitude and propagation in the rat dentate gyrus
    • Pan, E., and Stringer, J. L. (1996). Influence of osmolality on seizure amplitude and propagation in the rat dentate gyrus. Neurosci. Lett. 207, 9-12.
    • (1996) Neurosci. Lett. , vol.207 , pp. 9-12
    • Pan, E.1    Stringer, J.L.2
  • 132
    • 80052294692 scopus 로고    scopus 로고
    • Astrocytes are endogenous regulators of Basal transmission at central synapses
    • Panatier, A., Vallee, J., Haber, M., Murai, K. K., Lacaille, J. C., and Robitaille, R. (2011). Astrocytes are endogenous regulators of Basal transmission at central synapses. Cell 146, 785-798.
    • (2011) Cell , vol.146 , pp. 785-798
    • Panatier, A.1    Vallee, J.2    Haber, M.3    Murai, K.K.4    Lacaille, J.C.5    Robitaille, R.6
  • 135
    • 0030820823 scopus 로고    scopus 로고
    • Intracellu-lar calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ
    • Pasti, L., Volterra, A., Pozzan, T., and Carmignoto, G. (1997). Intracellu-lar calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ. J. Neurosci. 17, 7817-7830.
    • (1997) J. Neurosci. , vol.17 , pp. 7817-7830
    • Pasti, L.1    Volterra, A.2    Pozzan, T.3    Carmignoto, G.4
  • 136
    • 0017087432 scopus 로고
    • Regulation of extracellular potassium concentration in epileptogenesis
    • Pedley, T. A., Fisher, R. S., Futamachi, K. J., and Prince, D. A. (1976). Regulation of extracellular potassium concentration in epileptogenesis. Fed. Proc. 35, 1254-1259.
    • (1976) Fed. Proc. , vol.35 , pp. 1254-1259
    • Pedley, T.A.1    Fisher, R.S.2    Futamachi, K.J.3    Prince, D.A.4
  • 138
    • 14644388122 scopus 로고    scopus 로고
    • Perea, G., and Araque, A. (2005). Properties of synaptically evoked astro-cyte calcium signal reveal synaptic information processing by astrocytes. J. Nptically evoked astro-cyte calcium signal reveal synaptic information processing by astrocytes
    • (2005) J. Neurosci. , vol.25 , pp. 2192-2203
    • Perea, G.1    Araque, A.2
  • 139
    • 34548203204 scopus 로고    scopus 로고
    • Astrocytes potentiate transmitter release at single hippocampal synapses
    • Perea, G., and Araque, A. (2007). Astrocytes potentiate transmitter release at single hippocampal synapses. Science 317, 1083-1086.
    • (2007) Science , vol.317 , pp. 1083-1086
    • Perea, G.1    Araque, A.2
  • 140
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: astrocytes process and control synaptic information
    • Perea, G., Navarrete, M., and Araque, A. (2009). Tripartite synapses: astrocytes process and control synaptic information. Trends Neurosci. 32, 421-431.
    • (2009) Trends Neurosci , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 141
    • 80052419916 scopus 로고    scopus 로고
    • Role of astrocytes in neurovascular coupling
    • Petzold,G.C.,and Murthy,V.N. (2011). Role of astrocytes in neurovascular coupling. Neuron 71, 782-797.
    • (2011) Neuron , vol.71 , pp. 782-797
    • Petzold, G.C.1    Murthy, V.N.2
  • 143
    • 0029758991 scopus 로고    scopus 로고
    • Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals
    • Porter, J. T., and McCarthy, K. D. (1996). Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J. Neurosci. 16, 5073-5081.
    • (1996) J. Neurosci. , vol.16 , pp. 5073-5081
    • Porter, J.T.1    McCarthy, K.D.2
  • 144
    • 0014057494 scopus 로고
    • Control mechanisms in cortical epileptogenic foci "Surround" inhibition
    • Prince, D. A., and Wilder, B. J. (1967). Control mechanisms in cortical epileptogenic foci. "Surround" inhibition. Arch. Neurol. 16, 194-202.
    • (1967) Arch. Neurol. , vol.16 , pp. 194-202
    • Prince, D.A.1    Wilder, B.J.2
  • 146
    • 0028873970 scopus 로고
    • Biophysical and pharmacological characterization of inwardly rectifying K+ currents in rat spinal cord astrocytes
    • Ransom, C. B., and Sontheimer, H. (1995). Biophysical and pharmacological characterization of inwardly rectifying K+ currents in rat spinal cord astrocytes. J. Neurophysiol. 73, 333-346.
    • (1995) J. Neurophysiol. , vol.73 , pp. 333-346
    • Ransom, C.B.1    Sontheimer, H.2
  • 147
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: endogenous role in the human brain and therapeutic potentials. Prog
    • Reddy, D. S. (2010). Neurosteroids: endogenous role in the human brain and therapeutic potentials. Prog. Brain Res. 186,113-137.
    • (2010) Brain Res , vol.186 , pp. 113-137
    • Reddy, D.S.1
  • 149
    • 0028897095 scopus 로고
    • Cell death, glio-sis, and synaptic remodeling in the hippocampus of epileptic rats
    • Represa, A., Niquet, J., Pollard, H., and Ben-Ari, Y. (1995). Cell death, glio-sis, and synaptic remodeling in the hippocampus of epileptic rats. J. Neurobiol. 26,413-425.
    • (1995) J. Neurobiol. , vol.26 , pp. 413-425
    • Represa, A.1    Niquet, J.2    Pollard, H.3    Ben-Ari, Y.4
  • 151
    • 3042798891 scopus 로고    scopus 로고
    • The neurobiology of antiepileptic drugs
    • Rogawski, M. A., and Loscher, W. (2004). The neurobiology of antiepileptic drugs. Nat. Rev. Neurosci. 5, 553-564.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 553-564
    • Rogawski, M.A.1    Loscher, W.2
  • 152
    • 0026543575 scopus 로고
    • Osmolality and nonsy-naptic epileptiform bursts in rat CA1 and dentate gyrus
    • Roper, S. N., Obenaus, A., and Dudek, F. E. (1992). Osmolality and nonsy-naptic epileptiform bursts in rat CA1 and dentate gyrus. Ann. Neurol. 31, 81-85.
    • (1992) Ann. Neurol. , vol.31 , pp. 81-85
    • Roper, S.N.1    Obenaus, A.2    Dudek, F.E.3
  • 156
    • 0021286989 scopus 로고
    • Voltage-dependent inactivation of inward-rectifying single-channel currents in the guinea-pig heart cell membrane
    • Sakmann, B., and Trube, G. (1984). Voltage-dependent inactivation of inward-rectifying single-channel currents in the guinea-pig heart cell membrane. J. Physiol. 347, 659-683.
    • (1984) J. Physiol. , vol.347 , pp. 659-683
    • Sakmann, B.1    Trube, G.2
  • 157
    • 79952234841 scopus 로고    scopus 로고
    • TNFα controls glutamater-gic gliotransmission in the hippocampal dentate gyrus
    • Santello, M., Bezzi, P., and Volterra, A. (2011). TNFα controls glutamater-gic gliotransmission in the hippocampal dentate gyrus. Neuron 69, 988-1001.
    • (2011) Neuron , vol.69 , pp. 988-1001
    • Santello, M.1    Bezzi, P.2    Volterra, A.3
  • 158
    • 63449118968 scopus 로고    scopus 로고
    • Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy
    • Sarac, S., Afzal, S., Broholm, H., Mad-sen, E E, Ploug, T., and Laursen, H. (2009). Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy. APMIS 117,291-301.
    • (2009) APMIS , vol.117 , pp. 291-301
    • Sarac, S.1    Afzal, S.2    Broholm, H.3    Mad-sen, E.E.4    Ploug, T.5    Laursen, H.6
  • 160
    • 0033811922 scopus 로고    scopus 로고
    • Functional and molecular proper ties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy
    • Schroder, W., Hinterkeuser, S., Seifert, G., Schramm, J., Jabs, R., Wilkin, G. P., and Steinhauser, C. (2000). Functional and molecular proper ties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy. Epilepsia 41(SUPPL. 6), S181-S184.
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 6
    • Schroder, W.1    Hinterkeuser, S.2    Seifert, G.3    Schramm, J.4    Jabs, R.5    Wilkin, G.P.6    Steinhauser, C.7
  • 162
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: a molecular perspective
    • Seifert, G., Schilling, K., and Steinhauser, C. (2006). Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat. Rev. Neurosci. 7, 194-206.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3
  • 163
    • 4544312032 scopus 로고    scopus 로고
    • Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex
    • Seiffert, E., Dreier, J. P., Ivens, S., Bech-mann, I., Tomkins, O., Heinemann, U., and Friedman, A. (2004). Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J. Neurosci. 24, 7829-7836.
    • (2004) J. Neurosci. , vol.24 , pp. 7829-7836
    • Seiffert, E.1    Dreier, J.P.2    Ivens, S.3    Bech-mann, I.4    Tomkins, O.5    Heinemann, U.6    Friedman, A.7
  • 164
    • 33744999630 scopus 로고    scopus 로고
    • GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression
    • Serrano, A., Haddjeri, N., Lacaille, J. C., and Robitaille, R. (2006). GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression. J. Neurosci. 26,5370-5382.
    • (2006) J. Neurosci. , vol.26 , pp. 5370-5382
    • Serrano, A.1    Haddjeri, N.2    Lacaille, J.C.3    Robitaille, R.4
  • 165
    • 0033978239 scopus 로고    scopus 로고
    • +-elevating muscarinic cholinergic and histaminergic receptors in situ
    • +-elevating muscarinic cholinergic and histaminergic receptors in situ. J. Neurochem. 74, 555-563.
    • (2000) J. Neurochem. , vol.74 , pp. 555-563
    • Shelton, M.K.1    McCarthy, K.D.2
  • 166
    • 84555172978 scopus 로고    scopus 로고
    • TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3
    • Shigetomi, E., Tong, X., Kwan, K. Y., Corey, D. P., and Khakh, B. S. (2011). TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3. Nat. Neurosci. 15, 70-80.
    • (2011) Nat. Neurosci. , vol.15 , pp. 70-80
    • Shigetomi, E.1    Tong, X.2    Kwan, K.Y.3    Corey, D.P.4    Khakh, B.S.5
  • 172
    • 0032890096 scopus 로고    scopus 로고
    • Expression of the glutamate transporters in human temporal lobe epilepsy
    • Tessler, S., Danbolt, N. C., Faull, R. L., Storm-Mathisen, J., and Emson, P. C. (1999). Expression of the glutamate transporters in human temporal lobe epilepsy. Neuroscience 88, 1083-1091.
    • (1999) Neuroscience , vol.88 , pp. 1083-1091
    • Tessler, S.1    Danbolt, N.C.2    Faull, R.L.3    Storm-Mathisen, J.4    Emson, P.C.5
  • 179
    • 2942555126 scopus 로고    scopus 로고
    • Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy
    • Turrin, N. P., and Rivest, S. (2004). Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy. Neurobiol. Dis. 16, 321-334.
    • (2004) Neurobiol. Dis. , vol.16 , pp. 321-334
    • Turrin, N.P.1    Rivest, S.2
  • 180
    • 0034083370 scopus 로고    scopus 로고
    • Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures
    • Ulas, J., Satou, T., Ivins, K. J., Kesslak, J. P., Cotman, C. W., and Balazs, R. (2000). Expression of metabotropic glutamate receptor 5 is increased in astrocytes after kainate-induced epileptic seizures. Glia 30, 352-361.
    • (2000) Glia , vol.30 , pp. 352-361
    • Ulas, J.1    Satou, T.2    Ivins, K.J.3    Kesslak, J.P.4    Cotman, C.W.5    Balazs, R.6
  • 182
    • 46049103354 scopus 로고    scopus 로고
    • The role of cytokines in the pathophysiology of epilepsy
    • Vezzani, A., Balosso, S., and Rav-izza, T. (2008). The role of cytokines in the pathophysiology of epilepsy. Brain Behav. Immun. 22, 797-803.
    • (2008) Brain Behav. Immun. , vol.22 , pp. 797-803
    • Vezzani, A.1    Balosso, S.2    Ravizza, T.3
  • 183
    • 33644625777 scopus 로고    scopus 로고
    • Brain inflammation in epilepsy: experimental and clinical evidence
    • Vezzani, A., and Granata, T. (2005). Brain inflammation in epilepsy: experimental and clinical evidence. Epilepsia 46, 1724-1743.
    • (2005) Epilepsia , vol.46 , pp. 1724-1743
    • Vezzani, A.1    Granata, T.2
  • 185
    • 71549141314 scopus 로고    scopus 로고
    • The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroen-cephalographic study
    • Wang, Y., Zaveri, H. P., Lee, T. S., and Eid, T. (2009). The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroen-cephalographic study. Exp. Neurol. 220,293-302.
    • (2009) Exp. Neurol. , vol.220 , pp. 293-302
    • Wang, Y.1    Zaveri, H.P.2    Lee, T.S.3    Eid, T.4
  • 186
  • 187
    • 0029804572 scopus 로고    scopus 로고
    • Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide
    • Ye, Z. C., and Sontheimer, H. (1996). Cytokine modulation of glial glutamate uptake: a possible involvement of nitric oxide. Neuroreport 7, 2181-2185.
    • (1996) Neuroreport , vol.7 , pp. 2181-2185
    • Ye, Z.C.1    Sontheimer, H.2
  • 188
    • 0346599160 scopus 로고    scopus 로고
    • ATP released by astrocytes mediates glutamater-gic activity-dependent heterosynaptic suppression
    • Zhang, J.-M., Wang, H.-K., Ye, C.-Q., Ge, W., Chen, Y., Jiang, Z.-L., Wu, C.-P., Poo, M.-M., and Duan, S. (2003). ATP released by astrocytes mediates glutamater-gic activity-dependent heterosynaptic suppression. Neuron 40,971-982.
    • (2003) Neuron , vol.40 , pp. 971-982
    • Zhang, J.-M.1    Wang, H.-K.2    Ye, C.-Q.3    Ge, W.4    Chen, Y.5    Jiang, Z.-L.6    Wu, C.-P.7    Poo, M.-M.8    Duan, S.9
  • 190
    • 0036556337 scopus 로고    scopus 로고
    • Calcium oscillations encoding neuron-to-astrocyte communication
    • Zonta, M., and Carmignoto, G. (2002). Calcium oscillations encoding neuron-to-astrocyte communication. J. Physiol. Paris 96, 193-198.
    • (2002) J. Physiol. Paris , vol.96 , pp. 193-198
    • Zonta, M.1    Carmignoto, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.