-
1
-
-
0345099501
-
The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity
-
Burnett B, Li F, Pittman RN, (2003) The polyglutamine neurodegenerative protein ataxin-3 binds polyubiquitylated proteins and has ubiquitin protease activity. Hum Mol Genet 12 (23): 3195-3205.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.23
, pp. 3195-3205
-
-
Burnett, B.1
Li, F.2
Pittman, R.N.3
-
2
-
-
24744447434
-
Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin3
-
Berke SJ, Chai Y, Marrs GL, Wen H, Paulson HL, (2005) Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin3. J Biol Chem 280 (36): 32026-32034.
-
(2005)
J Biol Chem
, vol.280
, Issue.36
, pp. 32026-32034
-
-
Berke, S.J.1
Chai, Y.2
Marrs, G.L.3
Wen, H.4
Paulson, H.L.5
-
3
-
-
55549086868
-
The deubiquitinating enzyme ataxin-3, a polyglutamine protein, edits Lys63 linkages in mixed linkage ubiquitin chains
-
Winborn BJ, Travis SM, Todi SV, Scaglione KM, Xu P, et al. (2008) The deubiquitinating enzyme ataxin-3, a polyglutamine protein, edits Lys63 linkages in mixed linkage ubiquitin chains. J Biol Chem 283 (39): 26436-26443.
-
(2008)
J Biol Chem
, vol.283
, Issue.39
, pp. 26436-26443
-
-
Winborn, B.J.1
Travis, S.M.2
Todi, S.V.3
Scaglione, K.M.4
Xu, P.5
-
4
-
-
65849514220
-
SCA3: Neurological features, pathogenesis and animal models
-
Riess O, Rüb U, Pastore A, Bauer P, Schöls L, (2008) SCA3: Neurological features, pathogenesis and animal models. Cerebellum 7: 125-137.
-
(2008)
Cerebellum
, vol.7
, pp. 125-137
-
-
Riess, O.1
Rüb, U.2
Pastore, A.3
Bauer, P.4
Schöls, L.5
-
5
-
-
34147131206
-
Dominantly inherited ataxias: lessons learned from Machado-Joseph disease/spinocerebellar ataxia type 3
-
Paulson HL, (2007) Dominantly inherited ataxias: lessons learned from Machado-Joseph disease/spinocerebellar ataxia type 3. Semin Neurol 27 (2): 133-142.
-
(2007)
Semin Neurol
, vol.27
, Issue.2
, pp. 133-142
-
-
Paulson, H.L.1
-
6
-
-
69949170793
-
The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies
-
Bauer PO, Nukina N, (2009) The pathogenic mechanisms of polyglutamine diseases and current therapeutic strategies. J Neurochem 110 (6): 1737-1765.
-
(2009)
J Neurochem
, vol.110
, Issue.6
, pp. 1737-1765
-
-
Bauer, P.O.1
Nukina, N.2
-
7
-
-
77956184558
-
Neurotoxic protein oligomerisation associated with polyglutamine diseases
-
Hands SL, Wyttenbach A, (2010) Neurotoxic protein oligomerisation associated with polyglutamine diseases. Acta Neuropathol 120: 419-437.
-
(2010)
Acta Neuropathol
, vol.120
, pp. 419-437
-
-
Hands, S.L.1
Wyttenbach, A.2
-
8
-
-
0030850412
-
Intranuclear inclusions of expanded polyglutamine protein in spinocerebelar ataxia type 3
-
Paulson HL, Perez MK, Trottier Y, Trojanowski JQ, Subramony SH, et al. (1997) Intranuclear inclusions of expanded polyglutamine protein in spinocerebelar ataxia type 3. Neuron 19 (2): 333-344.
-
(1997)
Neuron
, vol.19
, Issue.2
, pp. 333-344
-
-
Paulson, H.L.1
Perez, M.K.2
Trottier, Y.3
Trojanowski, J.Q.4
Subramony, S.H.5
-
9
-
-
9244225693
-
Spinocerebellar ataxia 3 and Machado-Joseph disease: clinical, molecular and neuroathological features
-
Dürr A, Stevanin G, Cancel G, Duyckaerts C, Abbas N, et al. (1996) Spinocerebellar ataxia 3 and Machado-Joseph disease: clinical, molecular and neuroathological features. Ann Neurol 39 (4): 490-499.
-
(1996)
Ann Neurol
, vol.39
, Issue.4
, pp. 490-499
-
-
Dürr, A.1
Stevanin, G.2
Cancel, G.3
Duyckaerts, C.4
Abbas, N.5
-
10
-
-
0035833997
-
An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta-fibrils
-
Bevinino AE, Loll PJ, (2001) An expanded glutamine repeat destabilizes native ataxin-3 structure and mediates formation of parallel beta-fibrils. Proc Natl Acad Sci USA 98 (21): 11955-11960.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.21
, pp. 11955-11960
-
-
Bevinino, A.E.1
Loll, P.J.2
-
11
-
-
33947586837
-
Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein
-
Ellisdon AM, Pearce MC, Bottomley SP, (2007) Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein. J Mol Biol 368 (2): 595-605.
-
(2007)
J Mol Biol
, vol.368
, Issue.2
, pp. 595-605
-
-
Ellisdon, A.M.1
Pearce, M.C.2
Bottomley, S.P.3
-
12
-
-
0030936575
-
Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain
-
Paulson HL, Das SS, Crino PB, Perrez MK, Patel SC, et al. (1997) Machado-Joseph disease gene product is a cytoplasmic protein widely expressed in brain. Ann Neurol 41 (4): 453-462.
-
(1997)
Ann Neurol
, vol.41
, Issue.4
, pp. 453-462
-
-
Paulson, H.L.1
Das, S.S.2
Crino, P.B.3
Perrez, M.K.4
Patel, S.C.5
-
13
-
-
0032517816
-
Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation
-
Perez MK, Paulson HL, Pendse SJ, Saionz SJ, Bonini NM, et al. (1998) Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation. J Cell Biol 143 (6): 1457-1470.
-
(1998)
J Cell Biol
, vol.143
, Issue.6
, pp. 1457-1470
-
-
Perez, M.K.1
Paulson, H.L.2
Pendse, S.J.3
Saionz, S.J.4
Bonini, N.M.5
-
14
-
-
32144436256
-
Proteolytic cleavage of polyglutamine-expanded ataxin-3 is crucial for aggregation and sequestration of non-expanded ataxin-3
-
Haacke A, Broadley SA, Boteva R, Tzvetkov N, Hartl FU, et al. (2006) Proteolytic cleavage of polyglutamine-expanded ataxin-3 is crucial for aggregation and sequestration of non-expanded ataxin-3. Hum Mol Genet 15 (4): 555-568.
-
(2006)
Hum Mol Genet
, vol.15
, Issue.4
, pp. 555-568
-
-
Haacke, A.1
Broadley, S.A.2
Boteva, R.3
Tzvetkov, N.4
Hartl, F.U.5
-
15
-
-
26244434741
-
Towards a structural understannding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3
-
Gales L, Cortes L, Almeida C, Melo CV, do Carmo Costa M, et al. (2005) Towards a structural understannding of the fibrillization pathway in Machado-Joseph's disease: trapping early oligomers of non-expanded ataxin-3. J Mol Biol 353 (3): 642-654.
-
(2005)
J Mol Biol
, vol.353
, Issue.3
, pp. 642-654
-
-
Gales, L.1
Cortes, L.2
Almeida, C.3
Melo, C.V.4
do Carmo, C.M.5
-
16
-
-
33745195252
-
The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
-
Ellisdon AM, Thomas B, Bottomley SP, (2006) The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. J Biol Chem 281 (25): 16888-16896.
-
(2006)
J Biol Chem
, vol.281
, Issue.25
, pp. 16888-16896
-
-
Ellisdon, A.M.1
Thomas, B.2
Bottomley, S.P.3
-
17
-
-
0035968933
-
Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation
-
Nozaki K, Onodera O, Takano H, Tsuji S, (2001) Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation. Neuroreport 12 (15): 3357-3364.
-
(2001)
Neuroreport
, vol.12
, Issue.15
, pp. 3357-3364
-
-
Nozaki, K.1
Onodera, O.2
Takano, H.3
Tsuji, S.4
-
18
-
-
70349199064
-
Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins
-
Saunders HM, Bottomley SP, (2009) Multi-domain misfolding: understanding the aggregation pathway of polyglutamine proteins. Protein Eng Des Sel 22 (8): 447-451.
-
(2009)
Protein Eng Des Sel
, vol.22
, Issue.8
, pp. 447-451
-
-
Saunders, H.M.1
Bottomley, S.P.2
-
19
-
-
34247160537
-
Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3
-
Fei E, Jia N, Zhang T, Ma X, Wang H, et al. (2007) Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3. Biochem Biophys Res Commun 357 (2): 487-492.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, Issue.2
, pp. 487-492
-
-
Fei, E.1
Jia, N.2
Zhang, T.3
Ma, X.4
Wang, H.5
-
20
-
-
34447520352
-
Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence
-
Bichelmeier U, Schmidt T, Hubener J, Boy J, Ruttiger L, et al. (2007) Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence. J Neurosci 27 (28): 7418-7428.
-
(2007)
J Neurosci
, vol.27
, Issue.28
, pp. 7418-7428
-
-
Bichelmeier, U.1
Schmidt, T.2
Hubener, J.3
Boy, J.4
Ruttiger, L.5
-
21
-
-
60549100850
-
Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3
-
Todi SV, Winborn BJ, Scaglione KM, Blount JR, Travis SM, et al. (2009) Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin-3. EMBO J 28 (4): 372-382.
-
(2009)
EMBO J
, vol.28
, Issue.4
, pp. 372-382
-
-
Todi, S.V.1
Winborn, B.J.2
Scaglione, K.M.3
Blount, J.R.4
Travis, S.M.5
-
22
-
-
67149129949
-
Nucleocytoplasmic shuttling activity of ataxin-3
-
Macedo-Ribeiro S, Cortes L, Maciel P, Carvalho AL, (2009) Nucleocytoplasmic shuttling activity of ataxin-3. PLoS One 4 (6): e5834.
-
(2009)
PLoS One
, vol.4
, Issue.6
-
-
Macedo-Ribeiro, S.1
Cortes, L.2
Maciel, P.3
Carvalho, A.L.4
-
23
-
-
68749103450
-
CK2-dependent phosporylation determines cellular localization and stability of ataxin-3
-
Mueller T, Breuer P, Schmitt I, Walter J, Evert BO, et al. (2009) CK2-dependent phosporylation determines cellular localization and stability of ataxin-3. Hum Mol Genet 18 (17): 3334-3343.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.17
, pp. 3334-3343
-
-
Mueller, T.1
Breuer, P.2
Schmitt, I.3
Walter, J.4
Evert, B.O.5
-
24
-
-
34548410374
-
Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination
-
Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, et al. (2007) Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination. Biochem Biophys Res Commun 362 (3): 734-739.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, Issue.3
, pp. 734-739
-
-
Schmitt, I.1
Linden, M.2
Khazneh, H.3
Evert, B.O.4
Breuer, P.5
-
25
-
-
33747891213
-
Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates
-
Zhong X, Pittman RN, (2006) Ataxin-3 binds VCP/p97 and regulates retrotranslocation of ERAD substrates. Hum Mol Genet 15 (16): 2409-2420.
-
(2006)
Hum Mol Genet
, vol.15
, Issue.16
, pp. 2409-2420
-
-
Zhong, X.1
Pittman, R.N.2
-
26
-
-
77949450752
-
Proteotoxic stress increases nuclear localization of ataxin-3
-
Reina CP, Zhong X, Pittman RN, (2010) Proteotoxic stress increases nuclear localization of ataxin-3. Hum Mol Genet 19 (2): 235-249.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.2
, pp. 235-249
-
-
Reina, C.P.1
Zhong, X.2
Pittman, R.N.3
-
27
-
-
0033867992
-
Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, hHR23A and hHR23B
-
Wang G, Sawai N, Kotliarova S, Kanazawa I, Nukina N, (2000) Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, hHR23A and hHR23B. Hum Mol Genet 9 (12): 1795-1803.
-
(2000)
Hum Mol Genet
, vol.9
, Issue.12
, pp. 1795-1803
-
-
Wang, G.1
Sawai, N.2
Kotliarova, S.3
Kanazawa, I.4
Nukina, N.5
-
28
-
-
33645735557
-
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis
-
Boeddrich A, Gaumer S, Haacke A, Tzvetkov N, Albrecht M, et al. (2006) An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis. EMBO J 25 (7): 1547-1558.
-
(2006)
EMBO J
, vol.25
, Issue.7
, pp. 1547-1558
-
-
Boeddrich, A.1
Gaumer, S.2
Haacke, A.3
Tzvetkov, N.4
Albrecht, M.5
-
29
-
-
33750962224
-
Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation
-
Evert BO, Araujo J, Vieira-Saecker AM, de Vos RA, Harendza S, et al. (2006) Ataxin-3 represses transcription via chromatin binding, interaction with histone deacetylase 3, and histone deacetylation. J Neurosci 26 (44): 11474-11486.
-
(2006)
J Neurosci
, vol.26
, Issue.44
, pp. 11474-11486
-
-
Evert, B.O.1
Araujo, J.2
Vieira-Saecker, A.M.3
de Vos, R.A.4
Harendza, S.5
-
30
-
-
70350339099
-
Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin
-
Mazzucchelli S, De Palma A, Riva M, D'Urzo A, Pozzi C, et al. (2009) Proteomic and biochemical analyses unveil tight interaction of ataxin-3 with tubulin. Int J Biochem Cell Biol 41 (12): 2485-2492.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, Issue.12
, pp. 2485-2492
-
-
Mazzucchelli, S.1
de Palma, A.2
Riva, M.3
D'Urzo, A.4
Pozzi, C.5
-
31
-
-
63049109748
-
The ubiquitin receptor Rad23: at the crossroads of nucleotide excision repair and proteasomal degradation
-
Dantuma NP, Heinen C, Hoogstraten D, (2009) The ubiquitin receptor Rad23: at the crossroads of nucleotide excision repair and proteasomal degradation. DNA repair (Amst) 8 (4): 449-460.
-
(2009)
DNA Repair (Amst
, vol.8
, Issue.4
, pp. 449-460
-
-
Dantuma, N.P.1
Heinen, C.2
Hoogstraten, D.3
-
32
-
-
4143061786
-
Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of hHR23A
-
Raasi S, Orlov I, Fleming KG, Pickart CM, (2004) Binding of polyubiquitin chains to ubiquitin-associated (UBA) domains of hHR23A. J Mol Biol 341 (5): 1367-1379.
-
(2004)
J Mol Biol
, vol.341
, Issue.5
, pp. 1367-1379
-
-
Raasi, S.1
Orlov, I.2
Fleming, K.G.3
Pickart, C.M.4
-
33
-
-
70350297658
-
New ATPase regulators - p97 goes to the PUB
-
Madsen L, Seeger M, Semple CA, Hartmann-Petersen R, (2009) New ATPase regulators- p97 goes to the PUB. Int J Biochem Cell Biol 41 (12): 2380-2388.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, Issue.12
, pp. 2380-2388
-
-
Madsen, L.1
Seeger, M.2
Semple, C.A.3
Hartmann-Petersen, R.4
-
34
-
-
35748947239
-
Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity
-
Todi SV, Laco MN, Winborn BL, Travis SM, Wem HM, et al. (2007) Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity. J Biol Chem 282 (40): 29348-29358.
-
(2007)
J Biol Chem
, vol.282
, Issue.40
, pp. 29348-29358
-
-
Todi, S.V.1
Laco, M.N.2
Winborn, B.L.3
Travis, S.M.4
Wem, H.M.5
-
35
-
-
33744552664
-
Evidence for distinct functions for hman DNA repair factors hHR23A and hHR23B
-
Chen L, Madura K, (2006) Evidence for distinct functions for hman DNA repair factors hHR23A and hHR23B. FEBS Lett 580 (14): 3401-3408.
-
(2006)
FEBS Lett
, vol.580
, Issue.14
, pp. 3401-3408
-
-
Chen, L.1
Madura, K.2
-
36
-
-
0032425541
-
Heterogeneous intracellular localization and expression of ataxin-3
-
Trottier Y, Cancel G, An-Gourfinkel I, Lutz Y, Weber C, et al. (1998) Heterogeneous intracellular localization and expression of ataxin-3. Neurobiol Dis 5 (5): 335-347.
-
(1998)
Neurobiol Dis
, vol.5
, Issue.5
, pp. 335-347
-
-
Trottier, Y.1
Cancel, G.2
An-Gourfinkel, I.3
Lutz, Y.4
Weber, C.5
-
37
-
-
70349780383
-
Identification and functional dissection of localization signals within ataxin-3
-
Antony PM, Mämtele S, Mollenkopf P, Boy J, Kehlenbach RH, et al. (2009) Identification and functional dissection of localization signals within ataxin-3. Neurobiol Dis 36 (2): 280-292.
-
(2009)
Neurobiol Dis
, vol.36
, Issue.2
, pp. 280-292
-
-
Antony, P.M.1
Mämtele, S.2
Mollenkopf, P.3
Boy, J.4
Kehlenbach, R.H.5
-
38
-
-
23044515498
-
The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition
-
Nicastro G, Menon RP, Masino L, Knowles PP, McDonald NQ, et al. (2005) The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition. Proc Natl Acad Sci USA 102 (30): 10493-10498.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.30
, pp. 10493-10498
-
-
Nicastro, G.1
Menon, R.P.2
Masino, L.3
Knowles, P.P.4
McDonald, N.Q.5
-
39
-
-
77957879514
-
Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3
-
Nicastro G, Todi SV, Karaca E, Bonvin AM, Paulson HL, et al. (2010) Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3. PloS One 5 (8): e12430.
-
(2010)
PloS One
, vol.5
, Issue.8
-
-
Nicastro, G.1
Todi, S.V.2
Karaca, E.3
Bonvin, A.M.4
Paulson, H.L.5
-
40
-
-
67650457634
-
ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans
-
Rodrigues AJ, Neves-Carvalho A, Ferro A, Rokka A, Corthals G, et al. (2009) ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans. Biochem Biophys Res Commun 386 (4): 575-581.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, Issue.4
, pp. 575-581
-
-
Rodrigues, A.J.1
Neves-Carvalho, A.2
Ferro, A.3
Rokka, A.4
Corthals, G.5
-
41
-
-
0035846895
-
Membrane traffic: what drives the AAA motor?
-
Dalal S, Hanson PI, (2001) Membrane traffic: what drives the AAA motor? Cell 104: 5-8.
-
(2001)
Cell
, vol.104
, pp. 5-8
-
-
Dalal, S.1
Hanson, P.I.2
-
42
-
-
63349112395
-
p97/valosin-containing protein (VCP/p97) is highly modulated by phosphorylation and acetylation
-
Mori-Konya C, Kato N, Maeda R, Yasuda K, Higashimae N, et al. (2009) p97/valosin-containing protein (VCP/p97) is highly modulated by phosphorylation and acetylation. Genes Cells 14 (4): 483-497.
-
(2009)
Genes Cells
, vol.14
, Issue.4
, pp. 483-497
-
-
Mori-Konya, C.1
Kato, N.2
Maeda, R.3
Yasuda, K.4
Higashimae, N.5
-
43
-
-
0042691818
-
Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis
-
Doss-Pepe EW, Stenroos ES, Johnson WG, Madura K, (2003) Ataxin-3 interactions with rad23 and valosin-containing protein and its associations with ubiquitin chains and the proteasome are consistent with a role in ubiquitin-mediated proteolysis. Mol Cell Biol 23 (18): 6469-6483.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.18
, pp. 6469-6483
-
-
Doss-Pepe, E.W.1
Stenroos, E.S.2
Johnson, W.G.3
Madura, K.4
-
44
-
-
33748188085
-
Proteasome recruitment and activation of the Ucn37 deubiquitinating enzyme by Adrm1
-
Yao T, Song L, Xu W, DeMartino GN, Florens L, et al. (2006) Proteasome recruitment and activation of the Ucn37 deubiquitinating enzyme by Adrm1. Nat Cell Biol 8 (9): 994-1002.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.9
, pp. 994-1002
-
-
Yao, T.1
Song, L.2
Xu, W.3
DeMartino, G.N.4
Florens, L.5
-
45
-
-
36749082959
-
A UAF1-containing multisubunit complex regulates the Faconi anemia pathway
-
Cohn MA, Kowal P, Yang K, Haas W, Huang TT, et al. (2007) A UAF1-containing multisubunit complex regulates the Faconi anemia pathway. Mol Cell 28 (5): 786-797.
-
(2007)
Mol Cell
, vol.28
, Issue.5
, pp. 786-797
-
-
Cohn, M.A.1
Kowal, P.2
Yang, K.3
Haas, W.4
Huang, T.T.5
-
46
-
-
79952280797
-
The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis
-
Kuhlbrodt K, Janiesch PC, Kevei É, Segref A, Barikbin R, et al. (2011) The Machado-Joseph disease deubiquitylase ATX-3 couples longevity and proteostasis. Nat Cell Biol 13 (3): 273-281.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.3
, pp. 273-281
-
-
Kuhlbrodt, K.1
Janiesch, P.C.2
Kevei, É.3
Segref, A.4
Barikbin, R.5
-
47
-
-
33646582995
-
Conformational changes in the AAA ATPase p97-p47 adaptor complex
-
Beuron F, Dreveny I, Yuan X, Pye VE, McKeown C, et al. (2006) Conformational changes in the AAA ATPase p97-p47 adaptor complex. EMBO J 25 (9): 1967-1976.
-
(2006)
EMBO J
, vol.25
, Issue.9
, pp. 1967-1976
-
-
Beuron, F.1
Dreveny, I.2
Yuan, X.3
Pye, V.E.4
McKeown, C.5
-
48
-
-
0031803642
-
Ataxin-3 is transported into the nucleus and associates with the nuclear matrix
-
Tait D, Riccio M, Sittler A, Scerzinger E, Santi S, et al. (1998) Ataxin-3 is transported into the nucleus and associates with the nuclear matrix. Hum Mol Genet 7 (6): 991-997.
-
(1998)
Hum Mol Genet
, vol.7
, Issue.6
, pp. 991-997
-
-
Tait, D.1
Riccio, M.2
Sittler, A.3
Scerzinger, E.4
Santi, S.5
-
49
-
-
42649132458
-
Study of subcellular localization and proteolysis of ataxin-3
-
Pozzi C, Valtorta M, Tedeschi G, Galbusera E, Pastori V, et al. (2008) Study of subcellular localization and proteolysis of ataxin-3. Neurobiol Dis 30 (2): 190-200.
-
(2008)
Neurobiol Dis
, vol.30
, Issue.2
, pp. 190-200
-
-
Pozzi, C.1
Valtorta, M.2
Tedeschi, G.3
Galbusera, E.4
Pastori, V.5
-
50
-
-
0037047123
-
Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis
-
Chai Y, Shao J, Miller VM, Williams A, Paulson HL, (2002) Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis. Proc Natl Acad Sci USA 99 (14): 9310-9315.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.14
, pp. 9310-9315
-
-
Chai, Y.1
Shao, J.2
Miller, V.M.3
Williams, A.4
Paulson, H.L.5
-
51
-
-
29244480602
-
Proteasomes degrade proteins in focal subdomains of the human cell nucleus
-
Rockel TD, Stuhlmann D, von Mikecz A, (2005) Proteasomes degrade proteins in focal subdomains of the human cell nucleus. J Cell Sci 118 (22): 5231-5242.
-
(2005)
J Cell Sci
, vol.118
, Issue.22
, pp. 5231-5242
-
-
Rockel, T.D.1
Stuhlmann, D.2
von Mikecz, A.3
-
52
-
-
34249934582
-
Localization of proteasomes and proteasomal proteolysis in the mammalian interphase cell nucleus by systematic application of immunocytochemistry
-
Scharf A, Rockel TD, von Mikecz A, (2007) Localization of proteasomes and proteasomal proteolysis in the mammalian interphase cell nucleus by systematic application of immunocytochemistry. Histochem Cell Biol 127 (6): 591-601.
-
(2007)
Histochem Cell Biol
, vol.127
, Issue.6
, pp. 591-601
-
-
Scharf, A.1
Rockel, T.D.2
von Mikecz, A.3
-
53
-
-
34247349494
-
Defining how ubiquitin receptors hHR23A and S5a bind polyubiquitin
-
Kang Y, Chen X, Lary JW, Cole JL, Walters KJ, (2007) Defining how ubiquitin receptors hHR23A and S5a bind polyubiquitin. J Mol Biol 369 (1): 168-76.
-
(2007)
J Mol Biol
, vol.369
, Issue.1
, pp. 168-176
-
-
Kang, Y.1
Chen, X.2
Lary, J.W.3
Cole, J.L.4
Walters, K.J.5
-
54
-
-
25144453387
-
HHR23A, a human homolog of Saccharomyces cerevisiae Rad23, regulates xeroderma pigmentosum C protein and is required for nucleotide excision repair
-
Hsieh HC, Hsieh YH, Huang YH, Shen FC, Tsai FC, et al. (2005) HHR23A, a human homolog of Saccharomyces cerevisiae Rad23, regulates xeroderma pigmentosum C protein and is required for nucleotide excision repair. Biochem Biophys Res Commun 335 (19): 181-187.
-
(2005)
Biochem Biophys Res Commun
, vol.335
, Issue.19
, pp. 181-187
-
-
Hsieh, H.C.1
Hsieh, Y.H.2
Huang, Y.H.3
Shen, F.C.4
Tsai, F.C.5
-
55
-
-
0141891166
-
Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3
-
Evert BO, Vogt IR, Vieira-Saecker AM, Ozimek L, de Vos RA, et al. (2003) Gene expression profiling in ataxin-3 expressing cell lines reveals distinct effects of normal and mutant ataxin-3. J Neuropathol Exp Neurol 62 (10): 1006-1018.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, Issue.10
, pp. 1006-1018
-
-
Evert, B.O.1
Vogt, I.R.2
Vieira-Saecker, A.M.3
Ozimek, L.4
de Vos, R.A.5
-
56
-
-
0035425649
-
Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains
-
Evert BO, Vogt IR, Kindermann C, Ozimek L, de Vos RA, et al. (2001) Inflammatory genes are upregulated in expanded ataxin-3-expressing cell lines and spinocerebellar ataxia type 3 brains. J Neurosci 21 (15): 5389-5396.
-
(2001)
J Neurosci
, vol.21
, Issue.15
, pp. 5389-5396
-
-
Evert, B.O.1
Vogt, I.R.2
Kindermann, C.3
Ozimek, L.4
de Vos, R.A.5
-
57
-
-
35548938484
-
NEDD8: a new ataxin-3 interactor
-
Ferro A, Carvalho AL, Teixeira-Castro A, Almeida C, Tomé RJ, et al. (2007) NEDD8: a new ataxin-3 interactor. Biochem Biophys Acta 1773 (11): 1619-1627.
-
(2007)
Biochem Biophys Acta
, vol.1773
, Issue.11
, pp. 1619-1627
-
-
Ferro, A.1
Carvalho, A.L.2
Teixeira-Castro, A.3
Almeida, C.4
Tomé, R.J.5
-
58
-
-
53949117951
-
Casein kinase 2 interacts with and phosporylates ataxin-3
-
Tao RS, Fei EK, Ying Z, Wang HF, Wang GH, (2008) Casein kinase 2 interacts with and phosporylates ataxin-3. Neurosci Bull 24 (5): 271-7.
-
(2008)
Neurosci Bull
, vol.24
, Issue.5
, pp. 271-277
-
-
Tao, R.S.1
Fei, E.K.2
Ying, Z.3
Wang, H.F.4
Wang, G.H.5
-
59
-
-
79955964218
-
The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
-
Durcan TM, Kontogiannea M, Thorarinsdottir T, Fallon L, Williams AJ, et al. (2011) The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Hum Mol Genet 20 (1): 141-154.
-
(2011)
Hum Mol Genet
, vol.20
, Issue.1
, pp. 141-154
-
-
Durcan, T.M.1
Kontogiannea, M.2
Thorarinsdottir, T.3
Fallon, L.4
Williams, A.J.5
-
60
-
-
79952934390
-
Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain
-
Takeshita Y, Fujinaga R, Kokubu K, Islam MN, Jahan MR, et al. (2011) Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain. Neuroreport 22 (5): 232-238.
-
(2011)
Neuroreport
, vol.22
, Issue.5
, pp. 232-238
-
-
Takeshita, Y.1
Fujinaga, R.2
Kokubu, K.3
Islam, M.N.4
Jahan, M.R.5
-
61
-
-
43149099696
-
Inhibition of p97-dependent protein degradation by Eeyarestatin I
-
Wang Q, Li L, Ye Y, (2008) Inhibition of p97-dependent protein degradation by Eeyarestatin I. J Biol Chem 283 (12): 7445-7454.
-
(2008)
J Biol Chem
, vol.283
, Issue.12
, pp. 7445-7454
-
-
Wang, Q.1
Li, L.2
Ye, Y.3
-
62
-
-
20444391345
-
Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain
-
Varadan R, Assfalg M, Raasi S, Pickart C, Fushman D, (2005) Structural determinants for selective recognition of a Lys48-linked polyubiquitin chain by a UBA domain. Mol Cell 18 (6): 687-698.
-
(2005)
Mol Cell
, vol.18
, Issue.6
, pp. 687-698
-
-
Varadan, R.1
Assfalg, M.2
Raasi, S.3
Pickart, C.4
Fushman, D.5
-
63
-
-
1842766144
-
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
-
Venkatraman P, Wetzel R, Tanaka M, Nukina N, Goldberg AL, (2004) Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol Cell 14 (1): 95-104.
-
(2004)
Mol Cell
, vol.14
, Issue.1
, pp. 95-104
-
-
Venkatraman, P.1
Wetzel, R.2
Tanaka, M.3
Nukina, N.4
Goldberg, A.L.5
-
64
-
-
33746932115
-
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain
-
Díaz-Hernández M, Valera AG, Morán MA, Gómez-Ramos P, Alvarez-Castelao B, et al. (2006) Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain. J Neurochem 9: 1585-1596.
-
(2006)
J Neurochem
, vol.9
, pp. 1585-1596
-
-
Díaz-Hernández, M.1
Valera, A.G.2
Morán, M.A.3
Gómez-Ramos, P.4
Alvarez-Castelao, B.5
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