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Volumn 357, Issue 2, 2007, Pages 487-492

Phosphorylation of ataxin-3 by glycogen synthase kinase 3β at serine 256 regulates the aggregation of ataxin-3

Author keywords

Ataxin 3 (AT3); Glycogen synthase kinase 3 (GSK 3 ); Heat shock protein 70 (Hsp70); Machado Joseph disease (MJD); Phosphorylation

Indexed keywords

ATAXIN 1; ATAXIN 3; CHAPERONE; GLYCOGEN SYNTHASE KINASE 3BETA; HEAT SHOCK PROTEIN 70; HUNTINGTIN; POLYGLUTAMINE;

EID: 34247160537     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.03.160     Document Type: Article
Times cited : (47)

References (32)
  • 5
    • 0042027771 scopus 로고    scopus 로고
    • Polyglutamine diseases and molecular chaperones
    • Kimura Y., and Kakizuka A. Polyglutamine diseases and molecular chaperones. IUBMB Life 55 (2003) 337-345
    • (2003) IUBMB Life , vol.55 , pp. 337-345
    • Kimura, Y.1    Kakizuka, A.2
  • 6
    • 0034641589 scopus 로고    scopus 로고
    • Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity
    • Jana N.R., Tanaka M., Wang G., and Nukina N. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity. Human Molecular Genetics 9 (2000) 2009-2018
    • (2000) Human Molecular Genetics , vol.9 , pp. 2009-2018
    • Jana, N.R.1    Tanaka, M.2    Wang, G.3    Nukina, N.4
  • 7
    • 0037160106 scopus 로고    scopus 로고
    • Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities
    • Li F., Macfarlan T., Pittman R.N., and Chakravarti D. Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities. The Journal of Biological Chemistry 277 (2002) 45004-45012
    • (2002) The Journal of Biological Chemistry , vol.277 , pp. 45004-45012
    • Li, F.1    Macfarlan, T.2    Pittman, R.N.3    Chakravarti, D.4
  • 8
    • 0036198110 scopus 로고    scopus 로고
    • Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions
    • Schmidt T., Lindenberg K.S., Krebs A., Schols L., Laccone F., Herms J., Rechsteiner M., Riess O., and Landwehrmeyer G.B. Protein surveillance machinery in brains with spinocerebellar ataxia type 3: redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions. Annals of Neurology 51 (2002) 302-310
    • (2002) Annals of Neurology , vol.51 , pp. 302-310
    • Schmidt, T.1    Lindenberg, K.S.2    Krebs, A.3    Schols, L.4    Laccone, F.5    Herms, J.6    Rechsteiner, M.7    Riess, O.8    Landwehrmeyer, G.B.9
  • 11
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas J.J., Hernandez F., Gomez-Ramos P., Moran M.A., Hen R., and Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. The EMBO Journal 20 (2001) 27-39
    • (2001) The EMBO Journal , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 12
    • 22344439156 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity
    • Luo S., Vacher C., Davies J.E., and Rubinsztein D.C. Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity. The Journal of Cell Biology 169 (2005) 647-656
    • (2005) The Journal of Cell Biology , vol.169 , pp. 647-656
    • Luo, S.1    Vacher, C.2    Davies, J.E.3    Rubinsztein, D.C.4
  • 13
    • 0036606693 scopus 로고    scopus 로고
    • The GSK3 beta signaling cascade and neurodegenerative disease
    • Kaytor M.D., and Orr H.T. The GSK3 beta signaling cascade and neurodegenerative disease. Current Opinion in Neurobiology 12 (2002) 275-278
    • (2002) Current Opinion in Neurobiology , vol.12 , pp. 275-278
    • Kaytor, M.D.1    Orr, H.T.2
  • 14
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • Jope R.S., and Johnson G.V. The glamour and gloom of glycogen synthase kinase-3. Trends in Biochemical Sciences 29 (2004) 95-102
    • (2004) Trends in Biochemical Sciences , vol.29 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 15
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: tricks of the trade for a multi-tasking kinase
    • Doble B.W., and Woodgett J.R. GSK-3: tricks of the trade for a multi-tasking kinase. Journal of Cell Science 116 (2003) 1175-1186
    • (2003) Journal of Cell Science , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 16
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • Woodgett J.R. Molecular cloning and expression of glycogen synthase kinase-3/factor A. The EMBO Journal 9 (1990) 2431-2438
    • (1990) The EMBO Journal , vol.9 , pp. 2431-2438
    • Woodgett, J.R.1
  • 17
    • 0032989714 scopus 로고    scopus 로고
    • Developmental expression and localization of glycogen synthase kinase-3beta in rat brain
    • Leroy K., and Brion J.P. Developmental expression and localization of glycogen synthase kinase-3beta in rat brain. Journal of Chemical Neuroanatomy 16 (1999) 279-293
    • (1999) Journal of Chemical Neuroanatomy , vol.16 , pp. 279-293
    • Leroy, K.1    Brion, J.P.2
  • 18
    • 0034175688 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal
    • Hetman M., Cavanaugh J.E., Kimelman D., and Xia Z. Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal. Journal of Neuroscience 20 (2000) 2567-2574
    • (2000) Journal of Neuroscience , vol.20 , pp. 2567-2574
    • Hetman, M.1    Cavanaugh, J.E.2    Kimelman, D.3    Xia, Z.4
  • 19
    • 0037118247 scopus 로고    scopus 로고
    • Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
    • Jackson G.R., Wiedau-Pazos M., Sang T.K., Wagle N., Brown C.A., Massachi S., and Geschwind D.H. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34 (2002) 509-519
    • (2002) Neuron , vol.34 , pp. 509-519
    • Jackson, G.R.1    Wiedau-Pazos, M.2    Sang, T.K.3    Wagle, N.4    Brown, C.A.5    Massachi, S.6    Geschwind, D.H.7
  • 26
    • 33745195252 scopus 로고    scopus 로고
    • The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step
    • Ellisdon A.M., Thomas B., and Bottomley S.P. The two-stage pathway of ataxin-3 fibrillogenesis involves a polyglutamine-independent step. The Journal of Biological Chemistry 281 (2006) 16888-16896
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 16888-16896
    • Ellisdon, A.M.1    Thomas, B.2    Bottomley, S.P.3
  • 28
    • 0038039288 scopus 로고    scopus 로고
    • Polyglutamine protein aggregation and toxicity are linked to the cellular stress response
    • Cowan K.J., Diamond M.I., and Welch W.J. Polyglutamine protein aggregation and toxicity are linked to the cellular stress response. Human Molecular Genetics 12 (2003) 1377-1391
    • (2003) Human Molecular Genetics , vol.12 , pp. 1377-1391
    • Cowan, K.J.1    Diamond, M.I.2    Welch, W.J.3
  • 29
    • 33749177252 scopus 로고    scopus 로고
    • The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions
    • Tam S., Geller R., Spiess C., and Frydman J. The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions. Nature Cell Biology 8 (2006) 1155-1162
    • (2006) Nature Cell Biology , vol.8 , pp. 1155-1162
    • Tam, S.1    Geller, R.2    Spiess, C.3    Frydman, J.4
  • 31
    • 11144243412 scopus 로고    scopus 로고
    • Modulation of neurodegeneration by molecular chaperones
    • Muchowski P.J., and Wacker J.L. Modulation of neurodegeneration by molecular chaperones. Nature Reviews. Neuroscience 6 (2005) 11-22
    • (2005) Nature Reviews. Neuroscience , vol.6 , pp. 11-22
    • Muchowski, P.J.1    Wacker, J.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.