Understanding the role of the josephin domain in the polyub binding and cleavage properties of ataxin-3

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Nicastro, Giuseppe ^a   Todi, Sokol V ^b   Karaca, Ezgi ^c   Bonvin, Alexandre M J J ^c   Paulson, Henry L ^b   Pastore, Annalisa ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 3; POLYUBIQUITIN; ATXN3 PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; REPRESSOR PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; STRUCTURE ANALYSIS; CHEMISTRY; CONFORMATION; GENETICS; HUMAN; MACHADO JOSEPH DISEASE; METABOLISM; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE;

BINDING SITES; HUMANS; MACHADO-JOSEPH DISEASE; MOLECULAR CONFORMATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; POLYUBIQUITIN; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS;

EID: 77957879514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012430     Document Type: Article

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