Casein kinase 2 interacts with and phosphorylates ataxin-3

Neuroscience Bulletin

Volumn 24, Issue 5, 2008, Pages 271-277

  Tao, Rui Song ^a,b   Fei, Er Kang ^a   Ying, Zheng ^a   Wang, Hong Feng ^a   Wang, Guang Hui ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b HEFEI NORMAL UNIVERSITY   (China)

Author keywords

Ataxin 3; Casein kinase 2; Machado Joseph disease spinocerebellar ataxia type 3; Phosphorylation

Indexed keywords

ATAXIN 3; CASEIN KINASE II; GLUTATHIONE TRANSFERASE;

ALPHA CHAIN; ARTICLE; BETA CHAIN; EMBRYO; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; WILD TYPE;

CASEIN KINASE II; CELL LINE, TRANSFORMED; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOPRECIPITATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHOSPHORYLATION; REPRESSOR PROTEINS; TRANSFECTION;

EID: 53949117951     PISSN: 16737067     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12264-008-0605-5     Document Type: Article

References (34)

1. Y. Kawaguchi T. Okamoto M. Taniwaki M. Aizawa M. Inoue S. Katayama 1994 CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1 Nat Genet 8 221 228
2. C.J. Cummings H.Y. Zoghbi 2000 Trinucleotide repeats: mechanisms and pathophysiology Annu Rev Genomics Hum Genet 1 281 328
3. K. Nishiyama S. Murayama J. Goto M. Watanabe H. Hashida S. Katayama 1996 Regional and cellular expression of the Machado-Joseph disease gene in brains of normal and affected individuals Ann Neurol 40 776 781
4. M. Matsumoto M. Yada S. Hatakeyama H. Ishimoto T. Tanimura S. Tsuji 2004 Molecular clearance of ataxin-3 is regulated by a mammalian E4 Embo J 23 659 669
5. H.L. Paulson M.K. Perez Y. Trottier J.Q. Trojanowski S.H. Subramony S.S. Das 1997 Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3 Neuron 19 333 344
6. Y.E. Yan H. Wang M. Fan 2006 Molecular chaperones and neurodegenerative diseases Neurosci Bull 22 118 123
7. J.J. Lucas F. Hernandez P. Gomez-Ramos M.A. Moran R. Hen J. Avila 2001 Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice Embo J 20 27 39
8. G.R. Jackson M. Wiedau-Pazos T.K. Sang N. Wagle C.A. Brown S. Massachi 2002 Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila Neuron 34 509 519
9. S. Humbert E.A. Bryson F.P. Cordelieres N.C. Connors S.R. Datta S. Finkbeiner 2002 The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt Dev Cell 2 831 837
10. S.C. Warby E.Y. Chan M. Metzler L. Gan R.R. Singaraja S.F. Crocker 2005 Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo Hum Mol Genet 14 1569 1577
11. S. Luo C. Vacher J.E. Davies D.C. Rubinsztein 2005 Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity J Cell Biol 169 647 656
12. H.K. Chen P. Fernandez-Funez S.F. Acevedo Y.C. Lam M.D. Kaytor M.H. Fernandez 2003 Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1 Cell 113 457 468
13. E.S. Emamian M.D. Kaytor L.A. Duvick T. Zu S.K. Tousey H.Y. Zoghbi 2003 Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice Neuron 38 375 387
14. M. Okochi J. Walter A. Koyama S. Nakajo M. Baba T. Iwatsubo 2000 Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein J Biol Chem 275 390 397
15. C.C. Allende J.E. Allende 1998 Promiscuous subunit interactions: a possible mechanism for the regulation of protein kinase CK2 J Cell Biochem Suppl 30-31 129 136
16. L.A. Pinna 2002 Protein kinase CK2: a challenge to canons J Cell Sci 115 Pt20 3873 3878
17. B. Guerra O.G. Issinger 1999 Protein kinase CK2 and its role in cellular proliferation, development and pathology Electrophoresis 20 391 408
18. D.Y. Lou I. Dominguez P. Toselli E. Landesman-Bollag C. O'Brien D.C. Seldin 2008 The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development Mol Cell Biol 28 131 139
19. H. Fujiwara M. Hasegawa N. Dohmae A. Kawashima E. Masliah M.S. Goldberg 2002 Alpha-synuclein is phosphorylated in synucleinopathy lesions Nat Cell Biol 4 160 164
20. C. Liu E. Fei N. Jia H. Wang R. Tao A. Iwata 2007 Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated alpha-synuclein implies Lewy body biogenesis J Biol Chem 282 14558 14566
21. E. Fei N. Jia T. Zhang X. Ma H. Wang C. Liu 2007 Phosphorylation of ataxin-3 by glycogen synthase kinase 3beta at serine 256 regulates the aggregation of ataxin-3 Biochem Biophys Res Commun 357 487 492
22. A. Iwata M. Maruyama I. Kanazawa N. Nukina 2001 Alpha-synuclein affects the MAPK pathway and accelerates cell death J Biol Chem 276 45320 45329
23. G. Wang K. Ide N. Nukina J. Goto Y. Ichikawa K. Uchida 1997 Machado-Joseph disease gene product identified in lymphocytes and brain Biochem Biophys Res Commun 233 476 479
24. J.E. Allende C.C. Allende 1995 Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation Faseb J 9 313 323
25. M. Faust M. Montenarh 2000 Subcellular localization of protein kinase CK2. A key to its function? Cell Tissue Res 301 329 340
26. D. Tait M. Riccio A. Sittler E. Scherzinger S. Santi A. Ognibene 1998 Ataxin-3 is transported into the nucleus and associates with the nuclear matrix Hum Mol Genet 7 991 997
27. M. Albrecht M. Golatta U. Wullner T. Lengauer 2004 Structural and functional analysis of ataxin-2 and ataxin-3 Eur J Biochem 271 3155 3170
28. H.P. Rihs D.A. Jans H. Fan R. Peters 1991 The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen Embo J 10 633 639
29. U. Bichelmeier T. Schmidt J. Hubener J. Boy L. Ruttiger K. Habig 2007 Nuclear localization of ataxin-3 is required for the manifestation of symptoms in SCA3: in vivo evidence J Neurosci 27 7418 7428
30. L. Faccio C. Fusco A. Chen S. Martinotti J.V. Bonventre A.S. Zervos 2000 Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia J Biol Chem 275 2581 2588
31. C.W. Gray R.V. Ward E. Karran S. Turconi A. Rowles D. Viglienghi 2000 Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response Eur J Biochem 267 5699 5710
32. K.M. Strauss L.M. Martins H. Plun-Favreau F.P. Marx S. Kautzmann D. Berg 2005 Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease Hum Mol Genet 14 2099 2111
33. L. Yang M. Sun X.M. Sun G.Z. Cheng S.V. Nicosia J.Q. Cheng 2007 Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212 J Biol Chem 282 10981 10987
34. H. Plun-Favreau K. Klupsch N. Moisoi S. Gandhi S. Kjaer D. Frith 2007 The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1 Nat Cell Biol 9 1243 1252