Identification of direct forkhead box O1 targets involved in palmitate-induced apoptosis in clonal insulin-secreting cells using chromatin immunoprecipitation coupled to DNA selection and ligation

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2703-2712

  Lin, H Y ^a   Yin, Y ^a   Zhang, J X ^a   Xuan, H ^a   Zheng, Y ^a   Zhan, S S ^a   Zhu, Y X ^a   Han, X ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Clonal insulin secreting cells; Direct targets; FOXO1; Palmitate

Indexed keywords

DNA; FORKHEAD TRANSCRIPTION FACTOR; MESSENGER RNA; PALMITIC ACID; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DOWNSTREAM PROCESSING; GENE EXPRESSION; GENE TARGETING; GENETIC IDENTIFICATION; INSULIN RELEASE; MOUSE; NICK END LABELING; NONHUMAN; PALMITATE INDUCED APOPTOSIS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; DNA; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; INORGANIC PYROPHOSPHATASE; INSULIN-SECRETING CELLS; INSULINOMA; LUCIFERASES; MICE; MICE, INBRED STRAINS; NERVE GROWTH FACTORS; PALMITATES; PANCREATIC NEOPLASMS; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84866088263     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2643-9     Document Type: Article

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