D-Proline-based peptidomimetic inhibitors of anthrax lethal factor

European Journal of Medicinal Chemistry

Volumn 56, Issue , 2012, Pages 96-107

  Calugi, Chiara ^a   Trabocchi, Andrea ^a   Lalli, Claudia ^b   Guarna, Antonio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CNRS   (France)

Author keywords

Amino acid; Drug design; Enzyme; Molecular docking; Small molecule

Indexed keywords

3 (BENZYLOXY) 1 [(3,4 DICHLOROPHENYL)SULFONYL] N HYDROXYPYRROLIDINE 2 CARBOXAMIDE; HYDROXAMIC ACID DERIVATIVE; PEPTIDOMIMETIC AGENT; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG; ZINC;

ANTHRAX; ARTICLE; BINDING AFFINITY; DRUG BINDING SITE; DRUG CONFORMATION; DRUG DESIGN; DRUG SYNTHESIS; HYDROPHOBICITY; IC 50; LETHAL GENE; MOLECULAR DOCKING; MOLECULAR MODEL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANTIGENS, BACTERIAL; BACTERIAL TOXINS; HYDROXAMIC ACIDS; MODELS, MOLECULAR; PEPTIDOMIMETICS; PROLINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84865776101     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.08.028     Document Type: Article

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