Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency

American Journal of Physiology - Endocrinology and Metabolism

Volumn 303, Issue 5, 2012, Pages

  De Jonghe, Bart C ^a   Hayes, Matthew R ^b   Zimmer, Derek J ^a   Kanoski, Scott E ^a   Grill, Harvey J ^a   Bence, Kendra K ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Energy expenditure; Melanocortin 4 receptor; Melanotan II; Phosphatase; Proopiomelanocortin; Protein tyrosine phosphatase 1B

Indexed keywords

LEPTIN; MELANOCORTIN 4 RECEPTOR; MELANOTAN II; MESSENGER RNA; PROOPIOMELANOCORTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; BRAIN FOURTH VENTRICLE; CONTROLLED STUDY; CORE TEMPERATURE; ENERGY BALANCE; ENERGY EXPENDITURE; FEMALE; FOOD INTAKE; HYPOPHOSPHATASIA; HYPOPHYSIS; INTRACELLULAR SIGNALING; MALE; MOUSE; NERVE CELL; NONHUMAN; PHENOTYPE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TYROSINE PHOSPHATASE 1B DEFICIENCY; RHOMBENCEPHALON; SOLITARY TRACT NUCLEUS; WILD TYPE;

ALPHA-MSH; ANIMALS; APPETITE DEPRESSANTS; APPETITE REGULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION; INJECTIONS, INTRAVENTRICULAR; LEPTIN; MALE; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURONS; ORGAN SPECIFICITY; PEPTIDES, CYCLIC; PRO-OPIOMELANOCORTIN; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RECEPTOR, MELANOCORTIN, TYPE 3; RECEPTOR, MELANOCORTIN, TYPE 4; RHOMBENCEPHALON; RNA, MESSENGER;

EID: 84865748408     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00009.2012     Document Type: Article

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