The synergistic anti-inflammatory effects of lycopene, lutein, β-carotene, and carnosic acid combinations via redox-based inhibition of NF-κB signaling

Free Radical Biology and Medicine

Volumn 53, Issue 7, 2012, Pages 1381-1391

  Hadad, Nurit ^a   Levy, Rachel ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Carotenoids; Free radicals; Lycopene; NOX2 NADPH oxidase; Polyphenols; Proinflammatory mediators

Indexed keywords

BETA CAROTENE; CARNOSIC ACID; CYCLOOXYGENASE 2; DRINKING WATER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; LYC O MATO; LYCOPENE; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XANTHOPHYLL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATION REDUCTION REACTION; PERITONEAL CAVITY; PERITONEUM MACROPHAGE; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SUPPLEMENTATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETA CAROTENE; CAROTENOIDS; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; DITERPENES, ABIETANE; DRUG SYNERGISM; GENE EXPRESSION REGULATION; LIPOPOLYSACCHARIDES; LUTEIN; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED ICR; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; PERITONITIS; PLANT EXTRACTS; SIGNAL TRANSDUCTION; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84865742284     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.078     Document Type: Article

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