Insulin increases epiblast cell number of in vitro cultured mouse embryos via the PI3K/GSK3/p53 pathway

Stem Cells and Development

Volumn 21, Issue 13, 2012, Pages 2430-2441

  Campbell, Jared M ^a   Nottle, Mark B ^a   Vassiliev, Ivan ^a   Mitchell, Megan ^a   Lane, Michelle ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CT 99021; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN DERIVATIVE; INSULIN RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NICOTINAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; PHOSPHATIDYLINOSITOL 3 KINASE; PIFITHRIN ALPHA; PROTEIN P53; SIRTUIN 1; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BLASTOCYST; CELL COUNT; CELL CULTURE; CELL MATURATION; CONTROLLED STUDY; CULTURE MEDIUM; DRUG INHIBITION; DRUG MECHANISM; ECTODERM; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; BENZOTHIAZOLES; CELL COUNT; CHROMONES; CULTURE MEDIA; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; FEMALE; GERM LAYERS; GLYCOGEN SYNTHASE KINASE 3; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; INSULIN; ISOQUINOLINES; MALE; MICE; MICE, INBRED C57BL; MORPHOLINES; OCTAMER TRANSCRIPTION FACTOR-3; PHOSPHATIDYLINOSITOL 3-KINASES; PYRIDINES; PYRIMIDINES; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; SULFONAMIDES; TOLUENE; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865733458     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2011.0598     Document Type: Article

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