-
1
-
-
0031031523
-
Evidence for the requirement of autocrine growth factors for development of mouse preimplantation embryos in vitro
-
O'Neill C. Evidence for the requirement of autocrine growth factors for development of mouse preimplantation embryos in vitro. Biol Reprod 1997; 56:229-237.
-
(1997)
Biol Reprod
, vol.56
, pp. 229-237
-
-
O'Neill, C.1
-
2
-
-
0031965747
-
Autocrine mediators are required to act on the embryo by the 2- cell stage to promote normal development and survival of mouse preimplantation embryos in vitro
-
O'Neill C. Autocrine mediators are required to act on the embryo by the 2- cell stage to promote normal development and survival of mouse preimplantation embryos in vitro. Biol Reprod 1998; 58:1303-1309.
-
(1998)
Biol Reprod
, vol.58
, pp. 1303-1309
-
-
O'Neill, C.1
-
3
-
-
0036714938
-
Quiet please, do not disturb: A hypothesis of embryo metabolism and viability
-
Leese HJ. Quiet please, do not disturb: a hypothesis of embryo metabolism and viability. Bioessays 2002; 24:845-849.
-
(2002)
Bioessays
, vol.24
, pp. 845-849
-
-
Leese, H.J.1
-
4
-
-
0032450756
-
Human assisted conception: A cautionary tale. Lessons from domestic animals
-
Leese HJ, Donnay I, Thompson JG. Human assisted conception: a cautionary tale. Lessons from domestic animals. Hum Reprod 1998; 13(Suppl4):184-202.
-
(1998)
Hum Reprod
, vol.13
, Issue.SUPPL.4
, pp. 184-202
-
-
Leese, H.J.1
Donnay, I.2
Thompson, J.G.3
-
5
-
-
0025953465
-
The origin of reactive oxygen species in mouse embryos cultured in vitro
-
Nasr-Esfahani MM, Johnson MH. The origin of reactive oxygen species in mouse embryos cultured in vitro. Development 1991; 113:551-560.
-
(1991)
Development
, vol.113
, pp. 551-560
-
-
Nasr-Esfahani, M.M.1
Johnson, M.H.2
-
6
-
-
33947135830
-
Impact of transient stress and stress enzymes on development
-
Rappolee DA. Impact of transient stress and stress enzymes on development. Dev Biol 2007; 304:1-8.
-
(2007)
Dev Biol
, vol.304
, pp. 1-8
-
-
Rappolee, D.A.1
-
7
-
-
0031009264
-
Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients
-
Delhanty JD, Harper JC, Ao A, Handyside AH, Winston RM. Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients. Hum Genet 1997; 99:755-760.
-
(1997)
Hum Genet
, vol.99
, pp. 755-760
-
-
Delhanty, J.D.1
Harper, J.C.2
Ao, A.3
Handyside, A.H.4
Winston, R.M.5
-
8
-
-
0036851172
-
Epigenetic risks related to assisted reproductive technologies: Short- and long-term consequences for the health of children conceived through assisted reproduction technology: more reason for caution?
-
Thompson JG, Kind KL, Roberts CT, Robertson SA, Robinson JS. Epigenetic risks related to assisted reproductive technologies: short- and long-term consequences for the health of children conceived through assisted reproduction technology: more reason for caution? Hum Reprod 2002; 17:2783-2786.
-
(2002)
Hum Reprod
, vol.17
, pp. 2783-2786
-
-
Thompson, J.G.1
Kind, K.L.2
Roberts, C.T.3
Robertson, S.A.4
Robinson, J.S.5
-
9
-
-
0031982545
-
The p53 network
-
Agarwal M, Taylor WR, Chernov MV, Chernova OB, Stark GR. The p53 network. J Biol Chem 1998; 273:1-4
-
(1998)
J Biol Chem
, vol.273
, pp. 1-4
-
-
Agarwal, M.1
Taylor, W.R.2
Chernov, M.V.3
Chernova, O.B.4
Stark, G.R.5
-
10
-
-
33847217998
-
Culture of zygotes increases p53 expression in B6 mouse embryos which reduces embryo viability
-
Li A, Chandrakanthan V, Chami O, O'Neill C. Culture of zygotes increases p53 expression in B6 mouse embryos which reduces embryo viability. Biol Reprod 2007; 76:362-367.
-
(2007)
Biol Reprod
, vol.76
, pp. 362-367
-
-
Li, A.1
Chandrakanthan, V.2
Chami, O.3
O'Neill, C.4
-
11
-
-
36849003569
-
Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts
-
Chandrakanthan V, Chami O, Stojanov T, O'Neill C. Variable expressivity of the tumour suppressor protein TRP53 in cryopreserved human blastocysts. Reprod Biol Endocrinol 2007; 5:39.
-
(2007)
Reprod Biol Endocrinol
, vol.5
, pp. 39
-
-
Chandrakanthan, V.1
Chami, O.2
Stojanov, T.3
O'Neill, C.4
-
12
-
-
33845618080
-
Effects of in vitro fertilization and embryo culture on TRP53 and Bax expression in B6 mouse embryos
-
Chandrakanthan V, Li A, Chami O, O'Neill C. Effects of in vitro fertilization and embryo culture on TRP53 and Bax expression in B6 mouse embryos. Reprod Biol Endocrinol 2006; 4:61-67.
-
(2006)
Reprod Biol Endocrinol
, vol.4
, pp. 61-67
-
-
Chandrakanthan, V.1
Li, A.2
Chami, O.3
O'Neill, C.4
-
13
-
-
0031728455
-
Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways
-
Moley KH, Chi MM-Y, Knudson CM, Korsmeyer SJ, Mueckler MM. Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways. Nat Med 1998; 4:1421-1424.
-
(1998)
Nat Med
, vol.4
, pp. 1421-1424
-
-
Moley, K.H.1
Chi, M.M.-Y.2
Knudson, C.M.3
Korsmeyer, S.J.4
Mueckler, M.M.5
-
14
-
-
0034842413
-
Hyperglycemia-induced apoptotic cell death in the mouse blastocyst is dependent on expression of p53
-
Keim AL, Chi MM-Y, Moley KH. Hyperglycemia-induced apoptotic cell death in the mouse blastocyst is dependent on expression of p53. Mol Reprod Dev 2001; 60:214-224.
-
(2001)
Mol Reprod Dev
, vol.60
, pp. 214-224
-
-
Keim, A.L.1
Chi, M.M.-Y.2
Moley, K.H.3
-
15
-
-
0031987284
-
Transcriptional regulation of the p53 tumor suppressor gene
-
Reisman D, Loging WT. Transcriptional regulation of the p53 tumor suppressor gene. Semin Cancer Biol 1997; 8:317-324.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 317-324
-
-
Reisman, D.1
Loging, W.T.2
-
16
-
-
20344401786
-
Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development
-
Wells D, Bermudez MG, Steuerwald N, Thornhill AR, Walker DL, Malter H, Delhanty JDA, Cohen J. Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development. Hum Reprod 2005; 20:1339-1348.
-
(2005)
Hum Reprod
, vol.20
, pp. 1339-1348
-
-
Wells, D.1
Bermudez, M.G.2
Steuerwald, N.3
Thornhill, A.R.4
Walker, D.L.5
Malter, H.6
Delhanty, J.D.A.7
Cohen, J.8
-
17
-
-
20344373765
-
Association of abnormal morphology and altered gene expression in human preimplantation embryos
-
Wells D, Bermudez MG, Steuerwald N, Malter HE, Thornhill AR, Cohen J. Association of abnormal morphology and altered gene expression in human preimplantation embryos. Fertil Steril 2005; 84:343-355.
-
(2005)
Fertil Steril
, vol.84
, pp. 343-355
-
-
Wells, D.1
Bermudez, M.G.2
Steuerwald, N.3
Malter, H.E.4
Thornhill, A.R.5
Cohen, J.6
-
18
-
-
18344377030
-
The p53 pathway: Positive and negative feedback loops
-
Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005; 24:2899-2908.
-
(2005)
Oncogene
, vol.24
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
19
-
-
18144371656
-
The p53 response: Emerging levels of co-factor complexity
-
Coutts AS, Thangue NB. The p53 response: emerging levels of co-factor complexity. Biochem Biophys Res Commun 2005; 331:778-785.
-
(2005)
Biochem Biophys Res Commun
, vol.331
, pp. 778-785
-
-
Coutts, A.S.1
Thangue, N.B.2
-
21
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
Fang S, Jensen JP, Ludwig RL, Vousden KH, Weissman AM. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J Biol Chem 2000; 275:8945-8951.
-
(2000)
J Biol Chem
, vol.275
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.P.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
22
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
-
Jones SN, Roe AE, Donehower LA, Bradley A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 1995; 378: 206-208.
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
23
-
-
0028823020
-
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 1995; 378:203-205.
-
Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 1995; 378:203-205.
-
-
-
-
24
-
-
0041854343
-
A study of the nature of embryonic lethality in LIS1-/- mice
-
Cahana A, Jin XL, Reiner O, Wynshaw-Boris A, O'Neill C. A study of the nature of embryonic lethality in LIS1-/- mice. Mol Reprod Dev 2003; 66: 134-142.
-
(2003)
Mol Reprod Dev
, vol.66
, pp. 134-142
-
-
Cahana, A.1
Jin, X.L.2
Reiner, O.3
Wynshaw-Boris, A.4
O'Neill, C.5
-
25
-
-
0037999028
-
Ligand-activated signal transduction in the 2-cell embryo
-
Lu DP, Li Y, Bathgate R, Day M, O'Neill C. Ligand-activated signal transduction in the 2-cell embryo. Biol Reprod 2003; 69:106-116.
-
(2003)
Biol Reprod
, vol.69
, pp. 106-116
-
-
Lu, D.P.1
Li, Y.2
Bathgate, R.3
Day, M.4
O'Neill, C.5
-
26
-
-
0037387947
-
Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death
-
Schafer T, Scheuer C, Roemer K, Menger MD, Vollmar B. Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death. FASEB J 2003; 17:660-667.
-
(2003)
FASEB J
, vol.17
, pp. 660-667
-
-
Schafer, T.1
Scheuer, C.2
Roemer, K.3
Menger, M.D.4
Vollmar, B.5
-
27
-
-
0035949588
-
A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus
-
Mayo LD, Donner DB. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus. Proc Natl Acad Sci U S A 2001; 98:11598-11603.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11598-11603
-
-
Mayo, L.D.1
Donner, D.B.2
-
28
-
-
2342417682
-
Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre- implantation mouse embryo development
-
Lu DP, Chandrakanthan V, Cahana A, Ishii S, O'Neill C. Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre- implantation mouse embryo development. J Cell Sci 2004; 117:1567-1576.
-
(2004)
J Cell Sci
, vol.117
, pp. 1567-1576
-
-
Lu, D.P.1
Chandrakanthan, V.2
Cahana, A.3
Ishii, S.4
O'Neill, C.5
-
29
-
-
35548941073
-
-
Li Y, Chandrakanthan V, Day ML, O'Neill C. Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biol Reprod 2007; 77:813-821.
-
Li Y, Chandrakanthan V, Day ML, O'Neill C. Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biol Reprod 2007; 77:813-821.
-
-
-
-
30
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, Fotouhi N, Liu EA. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 2004; 303:844-848.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
32
-
-
0035145726
-
In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice
-
Stojanov T, O'Neill C. In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice. Biol Reprod 2001; 64:696-705.
-
(2001)
Biol Reprod
, vol.64
, pp. 696-705
-
-
Stojanov, T.1
O'Neill, C.2
-
33
-
-
4544284777
-
Effects of embryo culture on global pattern of gene expression in preimplantation mouse embryos
-
Rinaudo P, Schultz RM. Effects of embryo culture on global pattern of gene expression in preimplantation mouse embryos. Reprod 2004; 128: 301-311.
-
(2004)
Reprod
, vol.128
, pp. 301-311
-
-
Rinaudo, P.1
Schultz, R.M.2
-
34
-
-
34547843538
-
Effect of in vitro fertilization on gene expression and development of mouse preimplantation embryos
-
Giritharan G, Talb S, Donjacour A, Di Sebastiano F, Dobson A, Rinaudo P. Effect of in vitro fertilization on gene expression and development of mouse preimplantation embryos. Reprod 2007; 134:63-72.
-
(2007)
Reprod
, vol.134
, pp. 63-72
-
-
Giritharan, G.1
Talb, S.2
Donjacour, A.3
Di Sebastiano, F.4
Dobson, A.5
Rinaudo, P.6
-
35
-
-
0032996964
-
Ontogeny of expression of a receptor for platelet- activating factor in mouse preimplantation embryos and the effects of fertilisation and culture in vitro
-
Stojanov T, O'Neill C. Ontogeny of expression of a receptor for platelet- activating factor in mouse preimplantation embryos and the effects of fertilisation and culture in vitro. Biol Reprod 1999; 60:674-682.
-
(1999)
Biol Reprod
, vol.60
, pp. 674-682
-
-
Stojanov, T.1
O'Neill, C.2
-
36
-
-
0022343861
-
Partial characterisation of the embryo-derived platelet activating factor in mice
-
O'Neill C. Partial characterisation of the embryo-derived platelet activating factor in mice. J Reprod Fertil 1985; 75:375-380.
-
(1985)
J Reprod Fertil
, vol.75
, pp. 375-380
-
-
O'Neill, C.1
-
37
-
-
0034698166
-
Characterization and functional significance of calcium transients in the 2-cell mouse embryo induced by an autocrine growth factor
-
Emerson M, Travis AR, Bathgate R, Stojanov T, Cook DI, Harding E, Lu DP, O'Neill C. Characterization and functional significance of calcium transients in the 2-cell mouse embryo induced by an autocrine growth factor. J Biol Chem 2000; 275:21905-21913.
-
(2000)
J Biol Chem
, vol.275
, pp. 21905-21913
-
-
Emerson, M.1
Travis, A.R.2
Bathgate, R.3
Stojanov, T.4
Cook, D.I.5
Harding, E.6
Lu, D.P.7
O'Neill, C.8
-
38
-
-
18744401393
-
The role of paf in embryo physiology
-
O'Neill C. The role of paf in embryo physiology. Hum Reprod Update 2005; 11:215-228.
-
(2005)
Hum Reprod Update
, vol.11
, pp. 215-228
-
-
O'Neill, C.1
-
39
-
-
42549156818
-
The potential roles for embryotrophic ligands in preimplantation embryo development
-
O'Neill C. The potential roles for embryotrophic ligands in preimplantation embryo development. Hum Reprod Update 2008; 14:275-288.
-
(2008)
Hum Reprod Update
, vol.14
, pp. 275-288
-
-
O'Neill, C.1
-
40
-
-
50249176485
-
Phosphatidylinositol 3-kinase signaling in mammalian preimplantation embryo development
-
O'Neill C. Phosphatidylinositol 3-kinase signaling in mammalian preimplantation embryo development. Reprod 2008 136:147-156.
-
(2008)
Reprod
, vol.136
, pp. 147-156
-
-
O'Neill, C.1
-
41
-
-
33744492081
-
Glucose utilization and the PI3-K pathway: Mechanisms for cell survival in preimplantation embryos
-
Riley JK, Moley KH. Glucose utilization and the PI3-K pathway: mechanisms for cell survival in preimplantation embryos. Reprod 2006; 131:823-835.
-
(2006)
Reprod
, vol.131
, pp. 823-835
-
-
Riley, J.K.1
Moley, K.H.2
-
42
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
Marte BM, Downward J. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem Sci 1997; 22:355-358.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
43
-
-
0037053364
-
Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide- dependent protein kinase-1 in cells
-
Wick MJ, Wick KR, Chen H, He H, Dong LQ, Quon MJ, Liu F. Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide- dependent protein kinase-1 in cells. J Biol Chem 2002; 277:16632-16638.
-
(2002)
J Biol Chem
, vol.277
, pp. 16632-16638
-
-
Wick, M.J.1
Wick, K.R.2
Chen, H.3
He, H.4
Dong, L.Q.5
Quon, M.J.6
Liu, F.7
-
44
-
-
34548699897
-
p21 provides stage specific DNA damage control to preimplantation embryos
-
Adiga SK, Toyoshima M, Shiraishi K, Shimura T, Takeda J, Taga M, Nagai H, Kumar P, Niwa O. p21 provides stage specific DNA damage control to preimplantation embryos. Oncogene 2007; 26:6141-6149.
-
(2007)
Oncogene
, vol.26
, pp. 6141-6149
-
-
Adiga, S.K.1
Toyoshima, M.2
Shiraishi, K.3
Shimura, T.4
Takeda, J.5
Taga, M.6
Nagai, H.7
Kumar, P.8
Niwa, O.9
-
45
-
-
23944508588
-
The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo
-
Riley JK, Carayannopoulos MO, Wyman AH, Chi M, Ratajczak CK, Moley KH. The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo. Develop Biol 2005; 284:377-386.
-
(2005)
Develop Biol
, vol.284
, pp. 377-386
-
-
Riley, J.K.1
Carayannopoulos, M.O.2
Wyman, A.H.3
Chi, M.4
Ratajczak, C.K.5
Moley, K.H.6
-
46
-
-
12844273496
-
Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis
-
Gross V, Hess M, Cooper G. Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis. Mol Reprod Dev 2005; 70:324-332.
-
(2005)
Mol Reprod Dev
, vol.70
, pp. 324-332
-
-
Gross, V.1
Hess, M.2
Cooper, G.3
-
47
-
-
33947519632
-
Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system
-
Kawamura K, Kawamura N, Kumagai J, Fukuda J, Tanaka T. Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system. Biol Reprod 2007; 76:611-618.
-
(2007)
Biol Reprod
, vol.76
, pp. 611-618
-
-
Kawamura, K.1
Kawamura, N.2
Kumagai, J.3
Fukuda, J.4
Tanaka, T.5
-
48
-
-
34548284351
-
Involvement of protein kinase B/AKT in early development of mouse fertilized eggs
-
Feng C, Yu A, Liu Y, Zhang J, Zong Z, Su W, Zhang Z, Yu D, Sun Q-Y, Yu B. Involvement of protein kinase B/AKT in early development of mouse fertilized eggs. Biol Reprod 2007; 77:560-568.
-
(2007)
Biol Reprod
, vol.77
, pp. 560-568
-
-
Feng, C.1
Yu, A.2
Liu, Y.3
Zhang, J.4
Zong, Z.5
Su, W.6
Zhang, Z.7
Yu, D.8
Sun, Q.-Y.9
Yu, B.10
-
49
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic M, Alessi DR, Meier R, Fernandez A, Lamb NJC, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. Role of translocation in the activation and function of protein kinase B. J Biol Chem 1997; 272: 31515-31524.
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.J.C.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
50
-
-
4143053880
-
Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation
-
Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA. Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation. J Biol Chem 2004; 279: 35510-35517.
-
(2004)
J Biol Chem
, vol.279
, pp. 35510-35517
-
-
Feng, J.1
Tamaskovic, R.2
Yang, Z.3
Brazil, D.P.4
Merlo, A.5
Hess, D.6
Hemmings, B.A.7
-
51
-
-
0032518917
-
Nucleo- cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
-
Roth J, Dobbelstein M, Freedman DA, Shenk T, Levine AJ. Nucleo- cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J (1998); 17:554-564.
-
(1998)
EMBO J
, vol.17
, pp. 554-564
-
-
Roth, J.1
Dobbelstein, M.2
Freedman, D.A.3
Shenk, T.4
Levine, A.J.5
-
52
-
-
0042692785
-
Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination
-
O'Keefe K, Li H, Zhang Y. Nucleocytoplasmic shuttling of p53 is essential for MDM2-mediated cytoplasmic degradation but not ubiquitination. Mol Cell Biol 2003; 23:6396-6405.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 6396-6405
-
-
O'Keefe, K.1
Li, H.2
Zhang, Y.3
-
53
-
-
0348134742
-
Mono- versus polyubiquitination: Differential control of p53 fate by Mdm2
-
Li M, Brooks CL, Wu-Baer F, Chen D, Baer R, Gu W. Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science 2003; 302:1972-1975.
-
(2003)
Science
, vol.302
, pp. 1972-1975
-
-
Li, M.1
Brooks, C.L.2
Wu-Baer, F.3
Chen, D.4
Baer, R.5
Gu, W.6
-
54
-
-
0030665146
-
Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53
-
Mayo LD, Turchi JJ, Berberich SJ. Mdm-2 phosphorylation by DNA-dependent protein kinase prevents interaction with p53. Cancer Res 1997 57:5013-5016.
-
(1997)
Cancer Res
, vol.57
, pp. 5013-5016
-
-
Mayo, L.D.1
Turchi, J.J.2
Berberich, S.J.3
-
55
-
-
0035839460
-
Cyclin A-CDK phosphorylation regulates MDM2 protein interactions
-
Zhang T, Prives C. Cyclin A-CDK phosphorylation regulates MDM2 protein interactions. J Biol Chem 2001; 276:29702-29710.
-
(2001)
J Biol Chem
, vol.276
, pp. 29702-29710
-
-
Zhang, T.1
Prives, C.2
-
56
-
-
0033486046
-
Identification of a CK2 phosphorylation site in mdm2
-
Gotz C, Kartarius S, Scholtes P, Nastainczyk W, Montenarh M. Identification of a CK2 phosphorylation site in mdm2. Eur J Biochem 1999; 266:493-501.
-
(1999)
Eur J Biochem
, vol.266
, pp. 493-501
-
-
Gotz, C.1
Kartarius, S.2
Scholtes, P.3
Nastainczyk, W.4
Montenarh, M.5
-
57
-
-
0035339357
-
ATM-dependent phosphorylation of Mdm2 on serine 395: Role in p53 activation by DNA damage
-
Maya R, Balass M, Kim S-T, Shkedy D, Leal J-FM, Shifman O, Moas M, Buschmann T, Ronai Ze, Shiloh Y, Kastan MB, Katzir E, Oren M. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Genes Dev 2001; 15:1067-1077.
-
(2001)
Genes Dev
, vol.15
, pp. 1067-1077
-
-
Maya, R.1
Balass, M.2
Kim, S.-T.3
Shkedy, D.4
Leal, J.-F.M.5
Shifman, O.6
Moas, M.7
Buschmann, T.8
Ze, R.9
Shiloh, Y.10
Kastan, M.B.11
Katzir, E.12
Oren, M.13
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