Design, synthesis and functional analysis of dansylated polytheonamide mimic: An artificial peptide ion channel

Journal of the American Chemical Society

Volumn 134, Issue 34, 2012, Pages 14011-14018

  Itoh, Hiroaki ^a   Matsuoka, Shigeru ^a   Kreir, Mohamed ^b   Inoue, Masayuki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NANION TECHNOLOGIES GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; AMINO ACID SEQUENCE; ARTIFICIAL PEPTIDES; CYTOTOXIC; CYTOTOXINS; DEPROTECTION; EFFICIENT CONSTRUCTION; ION CHANNEL; ION TRANSPORTS; KEY FEATURE; LEUKEMIA CELLS; MEMBRANE LOCALIZATION; MULTI-STEP; POLYTHEONAMIDE B; PROPARGYL; PROTECTIVE GROUP; SCAFFOLD STRUCTURES; SOLID PHASE PEPTIDE SYNTHESIS; SYNTHETIC ION CHANNELS; TOTAL SYNTHESIS;

AMINO ACIDS; CHEMICAL BONDS; CYTOTOXICITY; FUNCTIONAL ANALYSIS; IONS; LIPID BILAYERS; LIPOSOMES; MOLECULES; PEPTIDES;

SYNTHESIS (CHEMICAL);

AMIDE; AMINO ACID; CYTOTOXIN; DANSYLATED POLYTHEONAMIDE; ION CHANNEL; POLYTHEONAMIDE B; PROPARGYLGLYCINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SYNTHESIS; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYTOTOXICITY; PROTEIN CLEAVAGE; PROTEIN SYNTHESIS; SOLID; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; BIOMIMETIC MATERIALS; CELL LINE, TUMOR; CELL SURVIVAL; ION CHANNELS; ION TRANSPORT; LEUKEMIA; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEINS; SOLID-PHASE SYNTHESIS TECHNIQUES; THEONELLA;

EID: 84865646614     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja303831a     Document Type: Article

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