Voltage-dependent behavior of a 'ball-and-chain' gramicidin channel

Biophysical Journal

Volumn 73, Issue 5, 1997, Pages 2465-2475

  Woolley, G Andrew ^a   Zunic, Valentin ^a   Karanicolas, John ^a   Jaikaran, Anna S I ^a   Starostin, Andrei V ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMIC ACID; GRAMICIDIN; GRAMICIDIN DERIVATIVE; GRAMICIDIN ETHYLENEDIAMINE; GRAMICIDIN N,N DIMETHYLETHYLENEDIAMINE; ION CHANNEL; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CIS TRANS ISOMERISM; ELECTRIC POTENTIAL; LIPID BILAYER; PH;

EID: 0030731890     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(97)78275-4     Document Type: Article

References (33)

1. Andersen, O. S. 1983. Ion movement through gramicidin A channels. Single-channel measurements at very high potentials. Biophys. J. 41:119-133.
2. Apell, H. J., E. Bamberg, H. Alpes, and P. Lauger. 1977. Formation of ion channels by a negatively charged analog of gramicidin A. J. Membr. Biol. 31:171-188.
3. Apell, H. J., E. Bamberg, and P. Lauger. 1979. Effects of surface charge on the conductance of the gramicidin channel. Biochim. Biophys. Acta. 552:369-378.
4. Bamberg, E., H. J. Apell, H. Alpes, E. Gross, J. L. Morell, J. F. Harbaugh, K. Janko, and P. Lauger. 1978. Ion channels formed by chemical analogs of gramicidin A. Fed. Proc. 37:2633-2638.
5. Busath, D. 1993. The use of physical methods in determining gramicidin channel structure and function. Annu. Rev. Physiol. 55:473-501.
6. 6.3-helices. Biophys. J. 53:689-695.
7. Cifu, A. S., R. E. Koeppe, II, and O. S. Andersen. 1992. On the supramolecular structure of gramicidin channels. The elementary conducting unit is a dimer. Biophys. J. 61:189-203.
8. Eisenman, G., J. Sandblom, and E. Neher. 1977. Ionic selectivity, saturation, binding, and block in the gramicidin A channel: a preliminary report. In Metal-Ligand Interactions in Organic Chemistry and Biochemistry. Part Two. D. Reidel Publishing Company, Dordrecht, the Netherlands. 1-36.
9. Heinemann, S. H., and F. J. Sigworth. 1988. Open channel noise. IV. Estimation of rapid kinetics of formamide block in gramicidin A channels. Biophys. J. 54:757-764.
10. Heinemann, S. H., and F. J. Sigworth. 1990. Open channel noise. V. Fluctuating barriers to ion entry in gramicidin A channels. Biophys. J. 57:499-.514.
11. Hemsley, G., and D. Busath. 1991. Small iminium ions block gramicidin channels in lipid bilayers. Biophys. J. 59:901-908.
12. Hille, B. 1992. Ionic Channels of Excitable Membranes. Sinauer Associates. Sunderland, MA.
13. Hinton, J. F., J. Q. Fernandez, D. C. Shungu, W. L. Whaley, R. E. Koeppe. II, and F. S. Millett. 1988. Tl-205 nuclear magnetic resonance determination of the thermodynamic parameters for the binding of monovalent cations to gramicidins A and C. Biophys. J. 54:527-533.
14. Jaikaran, D. C. J., and G. A. Woolley. 1995. Characterization of thermal isomerization at the single molecule level. J. Phys. Chem. 99: 13352-13355.
15. 16-gramicidin channel. Ph.D. thesis. Brown University, Providence, RI.
16. Jordan, P. C., R. J. Bacquct, J. A. McCammon, and P. Tran. 1989. How electrolyte shielding influences the electrical potential in transmembrane ion channels. Biophys. J. 55:1041-1052.
17. Ketchem, R. R., W. Hu, and T. A. Cross. 1993. High resolution structure of gramicidin in a lipid bilayer by solid-state NMR, Science. 261: 1457-1460.
18. Kirby, A. J. 1980. Effective molarities for intramolecular reactions. Adv. Phys. Org. Chem. 17:183-278.
19. Koeppe, R. E., II, and O. S. Andersen. 1996. Engineering the gramicidin channel. Annu. Rev. Biophys. Biomol. Struct. 25:231-258.
20. Lien, L., D. C. J. Jaikaran, Z. Zhang, and G. A. Woolley. 1996. Photo-modulated blocking of gramicidin ion channels. J. Am. Chem. Soc. 118:12222-12223.
21. + channel. Biochemistry. 28:8092-8099.
22. Myers, V. B., and D. A. Haydon. 1972. Ion transfer across lipid membranes in the presence of gramicidin A. II. The ion selectivity. Biochim. Biophys. Acta. 274:313-322.
23. Oiki, S., R. E. Koeppe, II, and O. S. Andersen. 1995. Voltage-dependent gating of an asymmetric gramicidin channel, Proc. Natl. Acad. Sci. USA. 92:2121-2125.
24. + translation along the single-file water chain in the gramicidin A channel. Biophys. J. 71:19-39.
25. + conduction in proton wires. Biophys. J. 72:A246.
26. Reinhardt, R., K. Janko, and E. Bamberg. 1986. Single channel conductance changes of the desethanolamine-gramicidin through pH variations. In Electrical Double Layers in Biology. Plenum Press, New York. 91-102.
27. 16]-gramicidin A. Biochim. Biophys. Acta. 982:223-227.
28. Roux, B., and M. Karplus. 1994. Molecular dynamics simulations of the gramicidin channel. Annu. Rev. Biophys. Biomol. Struct. 23:731-761.
29. Seoh, S. A., and D. Busath. 1993. The permeation properties of small organic cations in gramicidin A channels. Biophys. J. 64:1017-1028.
30. Stankovic, C. J., S. H. Heinemann, and S. L. Schreiber. 1991. Photo-modulated ion channels based on covalently linked gramicidins. Biochim. Biophys. Acta. 1061:163-170.
31. Sukhanov, S. V., B. B. Ivanov, S. Y. Orekhov, L. I. Barsukov, and A. S. Arseniev. 1993. Molecular design of photo-modulated ion channels based on gramicidin A and their electrochemical properties (in Russian). Biol. Membr. 10:535-543.
32. Woolley, G. A., A. S. I. Jaikaran, Z. Zhang, and S. Peng. 1995. Design of regulated ion channels using measurements of cis-trans isomerization in single molecules. J. Am. Chem. Soc. 117:4448-4454.
33. Woolley, G. A., A. S. I. Jaikaran, Z. Zhang, and S. Peng. 1996. Voltage-dependence of a designed ion channel. In Peptides: Chemistry, Structure and Biology. Mayflower Scientific, Kingswinford, England. 601-602.